PT1009832E - Citoquina designada lerk-6 - Google Patents
Citoquina designada lerk-6 Download PDFInfo
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- PT1009832E PT1009832E PT98945779T PT98945779T PT1009832E PT 1009832 E PT1009832 E PT 1009832E PT 98945779 T PT98945779 T PT 98945779T PT 98945779 T PT98945779 T PT 98945779T PT 1009832 E PT1009832 E PT 1009832E
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- lerk
- hek
- elk
- dna
- polypeptide
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/20—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans from protozoa
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F2013/00089—Wound bandages
- A61F2013/00153—Wound bandages coloured or with decoration pattern or printing
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
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- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (1)
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| US08/920,440 US5919905A (en) | 1994-10-05 | 1997-08-29 | Cytokine designated LERK-6 |
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| PT1009832E true PT1009832E (pt) | 2007-01-31 |
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| PT98945779T PT1009832E (pt) | 1997-08-29 | 1998-08-27 | Citoquina designada lerk-6 |
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| PT (1) | PT1009832E (enExample) |
| WO (1) | WO1999010495A1 (enExample) |
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| USRE37582E1 (en) | 1994-10-05 | 2002-03-12 | Immunex Corporation | Cytokine designated LERK-6 |
| US5919905A (en) * | 1994-10-05 | 1999-07-06 | Immunex Corporation | Cytokine designated LERK-6 |
| US20030228600A1 (en) * | 2000-07-14 | 2003-12-11 | Eppendorf 5 Prime, Inc. | DNA isolation method and kit |
| WO2003061570A2 (en) * | 2002-01-16 | 2003-07-31 | Zyomyx, Inc. | Engineered binding proteins |
| CA2486464A1 (en) | 2002-05-21 | 2003-11-27 | Resistentia Pharmaceuticals Ab | Chimeric ige polypeptides and host cells |
| AU2003268345A1 (en) | 2002-09-24 | 2004-04-19 | The Burnham Institute | Novel agents that modulate eph receptor activity |
| RS53476B (sr) | 2003-07-18 | 2014-12-31 | Amgen Fremont Inc. | Sredstva za specifično vezivanje faktora rasta hepatocita |
| CN101146822A (zh) | 2005-01-27 | 2008-03-19 | 伯纳姆研究所 | EphB受体结合肽 |
| PE20121506A1 (es) | 2006-07-14 | 2012-11-26 | Amgen Inc | Compuestos triazolopiridinas como inhibidores de c-met |
| US8217177B2 (en) | 2006-07-14 | 2012-07-10 | Amgen Inc. | Fused heterocyclic derivatives and methods of use |
| AU2008219166B2 (en) | 2007-02-16 | 2013-05-16 | Amgen Inc. | Nitrogen-containing heterocyclyl ketones and their use as c-Met inhibitors |
| TWI595005B (zh) | 2007-08-21 | 2017-08-11 | 安健股份有限公司 | 人類c-fms抗原結合蛋白質 |
| US20140302034A1 (en) * | 2010-12-08 | 2014-10-09 | Stem Centrx, Inc. | Novel modulators and methods of use |
| MY161199A (en) | 2011-03-23 | 2017-04-14 | Amgen Inc | Fused tricyclic dual inhibitors of cdk 4/6 and flt3 |
| US9745288B2 (en) | 2011-08-16 | 2017-08-29 | Indiana University Research And Technology Corporation | Compounds and methods for treating cancer by inhibiting the urokinase receptor |
| AR090263A1 (es) | 2012-03-08 | 2014-10-29 | Hoffmann La Roche | Terapia combinada de anticuerpos contra el csf-1r humano y las utilizaciones de la misma |
| US9505749B2 (en) | 2012-08-29 | 2016-11-29 | Amgen Inc. | Quinazolinone compounds and derivatives thereof |
| UY35148A (es) | 2012-11-21 | 2014-05-30 | Amgen Inc | Immunoglobulinas heterodiméricas |
| WO2014144817A2 (en) | 2013-03-15 | 2014-09-18 | Amgen Inc. | Inhibitory polypeptides specific to wnt inhibitors |
| TW201605896A (zh) | 2013-08-30 | 2016-02-16 | 安美基股份有限公司 | Gitr抗原結合蛋白 |
| WO2015035215A1 (en) | 2013-09-05 | 2015-03-12 | Amgen Inc. | Fc-containing molecules exhibiting predictable, consistent, and reproducible glycoform profiles |
| EP3065780A1 (en) | 2013-11-04 | 2016-09-14 | Pfizer Inc. | Anti-efna4 antibody-drug conjugates |
| EP3143404B1 (en) | 2014-05-16 | 2018-08-29 | Amgen Inc. | Assay for detecting th1 and th2 cell populations |
| JP6822961B2 (ja) * | 2014-12-19 | 2021-01-27 | ロレアル | 固体無水化粧用組成物、調製方法、美容処置方法及び関連キット |
| BR112018068103A2 (pt) | 2016-03-08 | 2019-01-15 | Janssen Biotech Inc | anticorpos gitr, métodos e usos |
| MX2019000514A (es) | 2016-07-14 | 2019-07-12 | Scholar Rock Inc | Anticuerpos de tgfb, métodos, y usos. |
| EP3558955B1 (en) | 2016-12-22 | 2021-08-11 | Amgen Inc. | Benzisothiazole, isothiazolo[3,4-b]pyridine, quinazoline, phthalazine, pyrido[2,3-d]pyridazine and pyrido[2,3-d]pyrimidine derivatives as kras g12c inhibitors for treating lung, pancreatic or colorectal cancer |
| CN110418846A (zh) | 2017-03-14 | 2019-11-05 | 美国安进公司 | 细胞培养物中产生的抗体的总去岩藻糖基化糖型的控制 |
| JOP20190272A1 (ar) | 2017-05-22 | 2019-11-21 | Amgen Inc | مثبطات kras g12c وطرق لاستخدامها |
| EP3679040B1 (en) | 2017-09-08 | 2022-08-03 | Amgen Inc. | Inhibitors of kras g12c and methods of using the same |
| SG11202009216YA (en) | 2018-03-26 | 2020-10-29 | Amgen Inc | Total afucosylated glycoforms of antibodies produced in cell culture |
| ES2995514T3 (en) | 2018-05-04 | 2025-02-10 | Amgen Inc | Kras g12c inhibitors and methods of using the same |
| AU2019262589B2 (en) | 2018-05-04 | 2022-07-07 | Amgen Inc. | KRAS G12C inhibitors and methods of using the same |
| MX2020011907A (es) | 2018-05-10 | 2021-01-29 | Amgen Inc | Inhibidores de kras g12c para el tratamiento de cancer. |
| ES2938987T3 (es) | 2018-06-01 | 2023-04-18 | Amgen Inc | Inhibidores de KRAS G12c y métodos de uso de los mismos |
| MX2020012204A (es) | 2018-06-11 | 2021-03-31 | Amgen Inc | Inhibidores de kras g12c para tratar el cáncer. |
| CA3100390A1 (en) | 2018-06-12 | 2020-03-12 | Amgen Inc. | Kras g12c inhibitors encompassing piperazine ring and use thereof in the treatment of cancer |
| JP7516029B2 (ja) | 2018-11-16 | 2024-07-16 | アムジエン・インコーポレーテツド | Kras g12c阻害剤化合物の重要な中間体の改良合成法 |
| JP7377679B2 (ja) | 2018-11-19 | 2023-11-10 | アムジエン・インコーポレーテツド | がん治療のためのkrasg12c阻害剤及び1種以上の薬学的に活性な追加の薬剤を含む併用療法 |
| WO2020106640A1 (en) | 2018-11-19 | 2020-05-28 | Amgen Inc. | Kras g12c inhibitors and methods of using the same |
| CA3123871A1 (en) | 2018-12-20 | 2020-06-25 | Amgen Inc. | Kif18a inhibitors |
| MA54546A (fr) | 2018-12-20 | 2022-03-30 | Amgen Inc | Amides d'hétéroaryle utiles en tant qu'inhibiteurs de kif18a |
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| JP7676308B2 (ja) | 2018-12-20 | 2025-05-14 | アムジエン・インコーポレーテツド | Kif18a阻害剤として有用なヘテロアリールアミド |
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| AU2020324406A1 (en) | 2019-08-02 | 2022-03-17 | Amgen Inc. | KIF18A inhibitors |
| MX2022001295A (es) | 2019-08-02 | 2022-02-22 | Amgen Inc | Inhibidores de kif18a. |
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| DE69334100T2 (de) * | 1992-11-13 | 2007-07-19 | Immunex Corp., Seattle | Elk ligand, ein cytokin |
| US5516658A (en) * | 1993-08-20 | 1996-05-14 | Immunex Corporation | DNA encoding cytokines that bind the cell surface receptor hek |
| US5457048A (en) * | 1993-12-03 | 1995-10-10 | La Jolla Cancer Research Foundation | Eph-related tyrosine kinases, nucleotide sequences and methods of use |
| US6268476B1 (en) * | 1994-09-19 | 2001-07-31 | President And Fellows Of Harvard College | EPH receptor ligands, and uses related thereto |
| US5795734A (en) * | 1994-09-19 | 1998-08-18 | President And Fellows Of Harvard College | EPH receptor ligands, and uses related thereto |
| ES2277335T3 (es) * | 1994-10-05 | 2007-07-01 | Immunex Corporation | Citoquina designada lerk-6. |
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| NZ301067A (en) * | 1994-12-06 | 1998-03-25 | Immunex Corp | Cytokine designated lerk-7 for activating tyrosine kinases |
| US6057124A (en) * | 1995-01-27 | 2000-05-02 | Amgen Inc. | Nucleic acids encoding ligands for HEK4 receptors |
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1998
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- 1998-08-27 ES ES98945779T patent/ES2273438T3/es not_active Expired - Lifetime
- 1998-08-27 DE DE69836088T patent/DE69836088T2/de not_active Expired - Fee Related
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- 1998-08-27 PT PT98945779T patent/PT1009832E/pt unknown
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| EP1009832B1 (en) | 2006-10-04 |
| WO1999010495A1 (en) | 1999-03-04 |
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| AU754368B2 (en) | 2002-11-14 |
| ATE341627T1 (de) | 2006-10-15 |
| NZ502884A (en) | 2002-04-26 |
| AU9294598A (en) | 1999-03-16 |
| US6232447B1 (en) | 2001-05-15 |
| ES2273438T3 (es) | 2007-05-01 |
| CA2301497A1 (en) | 1999-03-04 |
| US6472174B1 (en) | 2002-10-29 |
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| DK1009832T3 (da) | 2007-02-12 |
| EP1009832A1 (en) | 2000-06-21 |
| DE69836088T2 (de) | 2007-05-16 |
| JP2003532365A (ja) | 2003-11-05 |
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