PT100593A - 3-aril-beta-carbolinas ou 3-heteroaril-beta-carbolinas, processos para a sua preparacao e composicoes farmaceuticas que as contem - Google Patents

3-aril-beta-carbolinas ou 3-heteroaril-beta-carbolinas, processos para a sua preparacao e composicoes farmaceuticas que as contem Download PDF

Info

Publication number
PT100593A
PT100593A PT100593A PT10059392A PT100593A PT 100593 A PT100593 A PT 100593A PT 100593 A PT100593 A PT 100593A PT 10059392 A PT10059392 A PT 10059392A PT 100593 A PT100593 A PT 100593A
Authority
PT
Portugal
Prior art keywords
methoxymethyl
carboline
formula
alkyl
benzyloxy
Prior art date
Application number
PT100593A
Other languages
English (en)
Portuguese (pt)
Inventor
Lechoslaw Dr Turski
Andreas Huth
Dieter Seidelmann
Ralph Schmiechen
Herbert Schneider
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of PT100593A publication Critical patent/PT100593A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PT100593A 1991-06-15 1992-06-15 3-aril-beta-carbolinas ou 3-heteroaril-beta-carbolinas, processos para a sua preparacao e composicoes farmaceuticas que as contem PT100593A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4120109A DE4120109A1 (de) 1991-06-15 1991-06-15 3-aryl- oder 3-hetaryl-(beta)-carboline, deren herstellung und verwendung in arzneimitteln

Publications (1)

Publication Number Publication Date
PT100593A true PT100593A (pt) 1993-08-31

Family

ID=6434220

Family Applications (1)

Application Number Title Priority Date Filing Date
PT100593A PT100593A (pt) 1991-06-15 1992-06-15 3-aril-beta-carbolinas ou 3-heteroaril-beta-carbolinas, processos para a sua preparacao e composicoes farmaceuticas que as contem

Country Status (6)

Country Link
EP (1) EP0543968A1 (ja)
JP (1) JPH06501956A (ja)
CA (1) CA2089569A1 (ja)
DE (1) DE4120109A1 (ja)
PT (1) PT100593A (ja)
WO (1) WO1992022549A1 (ja)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4330175A1 (de) * 1993-08-31 1995-03-02 Schering Ag Alkoxy-substituierte beta-Carboline
EP1134221A1 (en) * 2000-03-15 2001-09-19 Aventis Pharma Deutschland GmbH Substituted beta-carbolines as lkB kinase inhibitors

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57123180A (en) * 1980-12-17 1982-07-31 Schering Ag 3-substituted beta-carboline, manufacture and psychotropic drug containing same
DE3240511A1 (de) * 1982-10-29 1984-05-03 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur herstellung von ss-carbolinderivaten
DE3322895A1 (de) * 1983-06-23 1985-01-03 Schering AG, 1000 Berlin und 4709 Bergkamen Neue ss-carboline, verfahren zur ihrer herstellung und ihre verwendung als arzneimittel (s)
DK240084D0 (da) * 1984-05-15 1984-05-15 Ferrosan As New beta-carboline-3-oxadiazolyl derivatives
DE3540654A1 (de) * 1985-11-13 1987-05-14 Schering Ag Phenoxy-substituierte ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel
DE3608089A1 (de) * 1986-03-08 1987-09-10 Schering Ag Heteroaryl-oxy-ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel
AU619203B2 (en) * 1987-08-28 1992-01-23 Schering Aktiengesellschaft Isoxazole-beta-carboline derivatives
DE3903753A1 (de) * 1989-02-06 1990-08-23 Schering Ag Verfahren zur herstellung waessriger mischmicelloesungen
DE3943225A1 (de) * 1989-12-23 1991-06-27 Schering Ag Neue ss-carboline, verfahren zu deren herstellung und deren verwendung in arzneimitteln

Also Published As

Publication number Publication date
EP0543968A1 (de) 1993-06-02
DE4120109A1 (de) 1992-12-17
WO1992022549A1 (de) 1992-12-23
CA2089569A1 (en) 1992-12-16
JPH06501956A (ja) 1994-03-03

Similar Documents

Publication Publication Date Title
AU694157B2 (en) Pyrazolopyridine adenosine antagonists
EP1605938B1 (en) Antibacterial derivatives of napthydrin and quinoline
CA3016182C (en) Substituted indole mcl-1 inhibitors
AU698133B2 (en) Heterobicyclic derivatives and use thereof as PDE IV and TNF inhibitors
US6818646B2 (en) Substituted pyrrolopyridinone derivatives useful as phosphodiesterase inhibitors
JP3569917B2 (ja) インターロイキン−１および腫瘍壊死因子阻害作用を有するピラゾリトリアジン
JP3514490B2 (ja) トリフルオロメチルピロロインドールカルボン酸エステル誘導体及びその製造方法
JP4704755B2 (ja) 抗菌剤
CN108368040A (zh) 二芳基单环β-内酰胺化合物及其用于治疗细菌感染的方法
SI9400091A (en) Substituted pyrrolo(2,3-b)pyridine derivatives
JP2008509222A (ja) 抗菌剤
WO2008113559A2 (en) Indolizines and aza-analog derivatives thereof as cns active compounds
AU2009267111A1 (en) Aza-indoles and related compounds having sphingosine-1-phosphate (S1P) receptor antagonist biological activity
CZ208496A3 (en) Pyrrolopyridazine derivatives
KR20010094731A (ko) 이미다졸 화합물 및 그의 의약 용도
FI88160B (fi) Foerfarande foer framstaellning av terapeutiskt anvaendbara isoxazolyl- -karboliner
JP2674199B2 (ja) 二環式アミン化合物およびその製造法
RU2093513C1 (ru) Производные 9-деазагуанины или их таутомеры и фармацевтическая композиция, обладающая способностью ингибировать активность пуриннуклеозид фосфорилазы у млекопитающих
JPH10237073A (ja) 新規な置換グアニジン誘導体およびその製法
PL165413B1 (pl) Sposób wytwarzania nowych pochodnych 6-arylo-5,6-dwuhydroimidazo [2,1-b] tiazolu PL PL
PT100593A (pt) 3-aril-beta-carbolinas ou 3-heteroaril-beta-carbolinas, processos para a sua preparacao e composicoes farmaceuticas que as contem
WO2009050348A1 (fr) Dérivés de λ/-hétéroaryl-carboxamides tricycliques, leur préparation et leur application en thérapeutique
WO1994021628A1 (en) Indole derivatives as dopamine d4 antagonists
EP0197533B1 (en) Dioxolobenzisoxazole derivatives and process for preparing the same
JP3068175B2 (ja) イソチアゾロ〔５，４―ｂ〕ピリジン誘導体

Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19930329

FC3A Refusal

Effective date: 19990419