PT1005458E - Derivados de carboestirilo para inibicao do eritema cutaneo e/ou da pigmentacao cutanea - Google Patents
Derivados de carboestirilo para inibicao do eritema cutaneo e/ou da pigmentacao cutaneaInfo
- Publication number
- PT1005458E PT1005458E PT98937851T PT98937851T PT1005458E PT 1005458 E PT1005458 E PT 1005458E PT 98937851 T PT98937851 T PT 98937851T PT 98937851 T PT98937851 T PT 98937851T PT 1005458 E PT1005458 E PT 1005458E
- Authority
- PT
- Portugal
- Prior art keywords
- cutaneous
- pct
- lower alkyl
- erythema
- carboxyryl
- Prior art date
Links
- 206010015150 Erythema Diseases 0.000 title abstract 2
- 231100000321 erythema Toxicity 0.000 title 1
- 230000005764 inhibitory process Effects 0.000 title 1
- 230000019612 pigmentation Effects 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- LISFMEBWQUVKPJ-UHFFFAOYSA-N quinolin-2-ol Chemical class C1=CC=C2NC(=O)C=CC2=C1 LISFMEBWQUVKPJ-UHFFFAOYSA-N 0.000 abstract 2
- 208000012641 Pigmentation disease Diseases 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 239000011203 carbon fibre reinforced carbon Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP22243197 | 1997-08-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT1005458E true PT1005458E (pt) | 2005-01-31 |
Family
ID=16782296
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT98937851T PT1005458E (pt) | 1997-08-19 | 1998-08-18 | Derivados de carboestirilo para inibicao do eritema cutaneo e/ou da pigmentacao cutanea |
Country Status (20)
Country | Link |
---|---|
US (1) | US6133264A (pt) |
EP (1) | EP1005458B1 (pt) |
JP (1) | JPH11124366A (pt) |
KR (1) | KR100397201B1 (pt) |
CN (1) | CN1141298C (pt) |
AR (1) | AR013945A1 (pt) |
AT (1) | ATE279395T1 (pt) |
AU (1) | AU725464B2 (pt) |
BR (1) | BR9811307A (pt) |
CA (1) | CA2297439C (pt) |
DE (1) | DE69827014T2 (pt) |
DK (1) | DK1005458T3 (pt) |
EG (1) | EG24161A (pt) |
ES (1) | ES2232001T3 (pt) |
HK (1) | HK1029346A1 (pt) |
ID (1) | ID23521A (pt) |
MY (1) | MY115907A (pt) |
PT (1) | PT1005458E (pt) |
TW (1) | TW436483B (pt) |
WO (1) | WO1999009011A1 (pt) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020034772A1 (en) | 1999-06-29 | 2002-03-21 | Orlow Seth J. | Methods and compositions that affect melanogenesis |
US20020114769A1 (en) * | 2000-09-14 | 2002-08-22 | Rotenberg Susan A. | Novel dequalinium analogs |
WO2011094016A1 (en) | 2010-01-28 | 2011-08-04 | New York University | Compounds, compositions and methods for preventing skin darkening |
US8772252B2 (en) | 2011-01-27 | 2014-07-08 | New York University | Coumarin compounds as melanogenesis modifiers and uses thereof |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1219587A (en) * | 1981-12-14 | 1987-03-24 | Norman P. Jensen | Hydroxybenzylaminobenzenes as anti-inflammatory agents |
US5082847A (en) * | 1990-07-18 | 1992-01-21 | Syntex (U.S.A.) Inc. | Carbostyril compounds connected via an oxyalkyl group with a piperidine ring and having pharmaceutical utility |
WO1993022317A1 (en) * | 1992-05-01 | 1993-11-11 | Kowa Co., Ltd. | Quinoline derivative or salt thereof and remedy for cardiac diseases containing the same |
TW448161B (en) * | 1994-07-14 | 2001-08-01 | Otsuka Pharma Co Ltd | Cyclic amide derivatives |
CA2226292C (en) * | 1995-07-07 | 2001-12-11 | Pfizer Inc. | Substituted benzolactam compounds as substance p antagonists |
JP2000511182A (ja) * | 1996-05-20 | 2000-08-29 | メルク エンド カンパニー インコーポレーテッド | 性腺刺激ホルモン放出ホルモンのアンタゴニスト |
EP0901471A4 (en) * | 1996-05-20 | 1999-08-25 | Merck & Co Inc | GONADOTROPIN RELEASING HORMONE ANTAGONISTS |
-
1998
- 1998-07-23 TW TW087112066A patent/TW436483B/zh not_active IP Right Cessation
- 1998-08-13 EG EG94298A patent/EG24161A/xx active
- 1998-08-17 JP JP10230407A patent/JPH11124366A/ja active Pending
- 1998-08-18 CA CA002297439A patent/CA2297439C/en not_active Expired - Fee Related
- 1998-08-18 AR ARP980104065A patent/AR013945A1/es active IP Right Grant
- 1998-08-18 MY MYPI98003752A patent/MY115907A/en unknown
- 1998-08-18 PT PT98937851T patent/PT1005458E/pt unknown
- 1998-08-18 KR KR10-2000-7001705A patent/KR100397201B1/ko not_active IP Right Cessation
- 1998-08-18 EP EP98937851A patent/EP1005458B1/en not_active Expired - Lifetime
- 1998-08-18 ID IDW20000312A patent/ID23521A/id unknown
- 1998-08-18 BR BR9811307-0A patent/BR9811307A/pt not_active IP Right Cessation
- 1998-08-18 US US09/485,454 patent/US6133264A/en not_active Expired - Fee Related
- 1998-08-18 DE DE69827014T patent/DE69827014T2/de not_active Expired - Fee Related
- 1998-08-18 ES ES98937851T patent/ES2232001T3/es not_active Expired - Lifetime
- 1998-08-18 AT AT98937851T patent/ATE279395T1/de not_active IP Right Cessation
- 1998-08-18 DK DK98937851T patent/DK1005458T3/da active
- 1998-08-18 WO PCT/JP1998/003657 patent/WO1999009011A1/en active IP Right Grant
- 1998-08-18 CN CNB988082772A patent/CN1141298C/zh not_active Expired - Fee Related
- 1998-08-18 AU AU86500/98A patent/AU725464B2/en not_active Ceased
-
2001
- 2001-01-11 HK HK01100255A patent/HK1029346A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE69827014T2 (de) | 2005-03-17 |
DE69827014D1 (de) | 2004-11-18 |
KR20010023086A (ko) | 2001-03-26 |
DK1005458T3 (da) | 2005-01-31 |
MY115907A (en) | 2003-09-30 |
TW436483B (en) | 2001-05-28 |
AU8650098A (en) | 1999-03-08 |
CA2297439C (en) | 2006-12-19 |
ES2232001T3 (es) | 2005-05-16 |
BR9811307A (pt) | 2000-08-29 |
AR013945A1 (es) | 2001-01-31 |
JPH11124366A (ja) | 1999-05-11 |
KR100397201B1 (ko) | 2003-09-13 |
EP1005458A1 (en) | 2000-06-07 |
HK1029346A1 (en) | 2001-03-30 |
ID23521A (id) | 2000-04-27 |
EP1005458B1 (en) | 2004-10-13 |
US6133264A (en) | 2000-10-17 |
CN1141298C (zh) | 2004-03-10 |
WO1999009011A1 (en) | 1999-02-25 |
CA2297439A1 (en) | 1999-02-25 |
ATE279395T1 (de) | 2004-10-15 |
AU725464B2 (en) | 2000-10-12 |
CN1267284A (zh) | 2000-09-20 |
EG24161A (en) | 2008-08-20 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HUP0002348A2 (hu) | A bőr mesterséges színezésére szolgáló szantalinokat vagy szantarubinokat tartalmazó kozmetikai készítmények | |
TR200202200T2 (tr) | Glükopiranosiloksibenzilbenzen türevleri, bu türevleri ihtiva eden tıbbi bileşimler ve türevlerin hazırlanması için ara-maddeler. | |
TW200420542A (en) | A compound having TGF β inhibition activity and a medicinal composition containing the same | |
EP1130017A3 (en) | Azole derivatives and their use as superoxide radical inhibitors | |
BR0014060A (pt) | Derivado de quinolil propil piperidina, processo para preparação do mesmo, e, composição farmacêutica | |
BRPI0616799B8 (pt) | derivado de piridina e derivado de pirimidina, composições farmacêuticas, usos, inibidores de angiogênese, contra receptor de fator de crescimento de hepatócito e contra metástase de câncer, e agente antitumor | |
BR9713417A (pt) | Composto de açúcar, agente gelificante, composição de agente gelificante, processos para suas preparações e composição de gel. | |
BR0109851A (pt) | Composto, método para produzir o mesmo ou um sal deste, pró medicamento, composição farmacêutica, método para inibir a tirosina cinase, método para prevenir ou tratar câncer, e, uso de um composto ou de um sal ou pró medicamento deste | |
HK1107814A1 (en) | Thiadiazoline derivatives for treating cancer | |
NO20004485D0 (no) | Sykloalkenderivater, deres fremstilling og anvendelse | |
EP1348706A4 (en) | SUBSTITUTED THIAZOLE DERIVATIVES CARRYING 3-PYRIDYL GROUPS, PROCESS FOR THEIR PRODUCTION AND USE THEREOF | |
CA2280905A1 (en) | Highly lipophilic camptothecin derivatives | |
KR960022486A (ko) | 신규 티아졸리딘-4-온 유도체 | |
PT1005458E (pt) | Derivados de carboestirilo para inibicao do eritema cutaneo e/ou da pigmentacao cutanea | |
BR0014615A (pt) | Derivado de ácido fosfÈnico que apresenta atividade inibidora contra carboxipeptidase b | |
AU7950100A (en) | 1-substituted phenyl-1-(1h-imidazol-4-yl) alcohols, process for producing the same and use thereof | |
MX9301985A (es) | Derivados de perhidroisoindol y procedimiento para su preparacion. | |
HUP0000966A2 (hu) | Izoflavonszármazékok és ilyen vegyületeket hatóanyagként tartalmazó gyógyszerkészítmények | |
ATE155791T1 (de) | Etoposid-derivate, ihre herstellung, ihre verwendung als medikament und ihre verwendung zur herstellung eines antikrebsmittels | |
BR0009856A (pt) | Sìntese de 3-amino-3-aril propanoatos | |
DE60203029D1 (de) | Benzopyran Derivate und diese enthaltende Antiallergisches Mittel | |
DE69528984T2 (de) | Hemmung der leukotrienbiosynthese mittels harnstoffderivaten | |
NO940984L (no) | Benzen-derivater |