BR9811307A - Derivado de carboestirila ou um sal deste, agentes para prevenir e tratar dermatopatia ou dermatite e para inibir o eritema da pele e/ou pigmentação da pele, composto, uso de um composto, e, processo para preparar um derivado de carboestirila - Google Patents

Derivado de carboestirila ou um sal deste, agentes para prevenir e tratar dermatopatia ou dermatite e para inibir o eritema da pele e/ou pigmentação da pele, composto, uso de um composto, e, processo para preparar um derivado de carboestirila

Info

Publication number
BR9811307A
BR9811307A BR9811307-0A BR9811307A BR9811307A BR 9811307 A BR9811307 A BR 9811307A BR 9811307 A BR9811307 A BR 9811307A BR 9811307 A BR9811307 A BR 9811307A
Authority
BR
Brazil
Prior art keywords
compound
carbohydrate derivative
salt
skin
dermatopathy
Prior art date
Application number
BR9811307-0A
Other languages
English (en)
Inventor
Yasuo Oshiro
Takao Nishi
Keiichi Kuwahara
Kozo Watanabe
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of BR9811307A publication Critical patent/BR9811307A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C07D215/26—Alcohols; Ethers thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)

Abstract

"DERIVADO DE CARBOESTIRILA OU UM SAL DESTE, AGENTES PARA PREVENIR E TRATAR DERMATOPATIA OU DERMATITE E PARA INIBIR O ERITEMA DA PELE E/OU PIGMENTAçãO DA PELE, COMPOSTO, USO DE UM COMPOSTO, E, PROCESSO PARA PREPARAR UM DERIVADO DE CARBOESTIRILA". A presente invenção fornece um agente para inibir eritema e/ou pigmentação da pele contendo pelo menos um selecionado do grupo consistindo do derivado de carboestirila e seu sal representado pela fórmula geral (1): onde R^ 1^ é um átomo de hidrogênio, um grupo alquila inferior ou coisa parecida; R^ 2^ é um átomo de hidrogênio, um grupo alquila inferior, um grupo alcóxi inferior ou coisa parecida, R^ 3^ e R^ 4^ são grupos alquila inferior que podem ter grupos hidroxila como substituintes ou coisa parecida, a ligação carbono-carbono entre as posições 3 e 4 na estrutura de carboestirila é uma ligação simples ou uma ligação dupla.
BR9811307-0A 1997-08-19 1998-08-18 Derivado de carboestirila ou um sal deste, agentes para prevenir e tratar dermatopatia ou dermatite e para inibir o eritema da pele e/ou pigmentação da pele, composto, uso de um composto, e, processo para preparar um derivado de carboestirila BR9811307A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP22243197 1997-08-19
PCT/JP1998/003657 WO1999009011A1 (en) 1997-08-19 1998-08-18 Carbostyril derivatives for inhibiting skin erythema and/or skin pigmentation

Publications (1)

Publication Number Publication Date
BR9811307A true BR9811307A (pt) 2000-08-29

Family

ID=16782296

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9811307-0A BR9811307A (pt) 1997-08-19 1998-08-18 Derivado de carboestirila ou um sal deste, agentes para prevenir e tratar dermatopatia ou dermatite e para inibir o eritema da pele e/ou pigmentação da pele, composto, uso de um composto, e, processo para preparar um derivado de carboestirila

Country Status (20)

Country Link
US (1) US6133264A (pt)
EP (1) EP1005458B1 (pt)
JP (1) JPH11124366A (pt)
KR (1) KR100397201B1 (pt)
CN (1) CN1141298C (pt)
AR (1) AR013945A1 (pt)
AT (1) ATE279395T1 (pt)
AU (1) AU725464B2 (pt)
BR (1) BR9811307A (pt)
CA (1) CA2297439C (pt)
DE (1) DE69827014T2 (pt)
DK (1) DK1005458T3 (pt)
EG (1) EG24161A (pt)
ES (1) ES2232001T3 (pt)
HK (1) HK1029346A1 (pt)
ID (1) ID23521A (pt)
MY (1) MY115907A (pt)
PT (1) PT1005458E (pt)
TW (1) TW436483B (pt)
WO (1) WO1999009011A1 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020034772A1 (en) 1999-06-29 2002-03-21 Orlow Seth J. Methods and compositions that affect melanogenesis
US20020114769A1 (en) * 2000-09-14 2002-08-22 Rotenberg Susan A. Novel dequalinium analogs
US8563754B2 (en) 2010-01-28 2013-10-22 New York University Compounds, compositions and methods for preventing skin darkening
WO2012103487A1 (en) 2011-01-27 2012-08-02 New York University Coumarin compounds as melanogenesis modifiers and uses thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1219587A (en) * 1981-12-14 1987-03-24 Norman P. Jensen Hydroxybenzylaminobenzenes as anti-inflammatory agents
US5082847A (en) * 1990-07-18 1992-01-21 Syntex (U.S.A.) Inc. Carbostyril compounds connected via an oxyalkyl group with a piperidine ring and having pharmaceutical utility
US5576324A (en) * 1992-05-01 1996-11-19 Kowa Co., Ltd. Quinoline derivatives or salt thereof and remedy for cardiac diseases containing the same
TW448161B (en) * 1994-07-14 2001-08-01 Otsuka Pharma Co Ltd Cyclic amide derivatives
EP0840732B1 (en) * 1995-07-07 2001-03-07 Pfizer Inc. Substituted benzolactam compounds as substance p antagonists
WO1997044321A1 (en) * 1996-05-20 1997-11-27 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
JP2000511182A (ja) * 1996-05-20 2000-08-29 メルク エンド カンパニー インコーポレーテッド 性腺刺激ホルモン放出ホルモンのアンタゴニスト

Also Published As

Publication number Publication date
AR013945A1 (es) 2001-01-31
AU8650098A (en) 1999-03-08
ES2232001T3 (es) 2005-05-16
ATE279395T1 (de) 2004-10-15
DK1005458T3 (da) 2005-01-31
EG24161A (en) 2008-08-20
CA2297439C (en) 2006-12-19
PT1005458E (pt) 2005-01-31
WO1999009011A1 (en) 1999-02-25
DE69827014T2 (de) 2005-03-17
EP1005458B1 (en) 2004-10-13
KR100397201B1 (ko) 2003-09-13
AU725464B2 (en) 2000-10-12
MY115907A (en) 2003-09-30
EP1005458A1 (en) 2000-06-07
HK1029346A1 (en) 2001-03-30
KR20010023086A (ko) 2001-03-26
JPH11124366A (ja) 1999-05-11
CN1141298C (zh) 2004-03-10
US6133264A (en) 2000-10-17
ID23521A (id) 2000-04-27
TW436483B (en) 2001-05-28
CN1267284A (zh) 2000-09-20
CA2297439A1 (en) 1999-02-25
DE69827014D1 (de) 2004-11-18

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: ALTERADA DE INT.CL: C07D 215/227, C07D 215/26, C07D 405/12, C07D 215/00, C07D 405/00, A61K 31/4704, A61K 31/47

Ipc: C07D 215/227 (2008.04), C07D 215/26 (2008.04), C07

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 12A E 13A ANUIDADE(S).

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2125 DE 27/09/2011.