PL86974B1 - Basic ethers[au6018473a] - Google Patents
Basic ethers[au6018473a] Download PDFInfo
- Publication number
- PL86974B1 PL86974B1 PL1973165129A PL16512973A PL86974B1 PL 86974 B1 PL86974 B1 PL 86974B1 PL 1973165129 A PL1973165129 A PL 1973165129A PL 16512973 A PL16512973 A PL 16512973A PL 86974 B1 PL86974 B1 PL 86974B1
- Authority
- PL
- Poland
- Prior art keywords
- radical
- formula
- hal
- alkyl
- basic
- Prior art date
Links
- 150000002170 ethers Chemical class 0.000 title claims abstract 6
- -1 PhCH 2 Chemical group 0.000 claims abstract 19
- 150000003839 salts Chemical class 0.000 claims abstract 14
- 150000001875 compounds Chemical class 0.000 claims abstract 7
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 claims abstract 6
- 125000000217 alkyl group Chemical group 0.000 claims abstract 6
- 125000004432 carbon atom Chemical group C* 0.000 claims abstract 5
- 125000003342 alkenyl group Chemical group 0.000 claims abstract 4
- 125000000262 haloalkenyl group Chemical group 0.000 claims abstract 4
- 125000000304 alkynyl group Chemical group 0.000 claims abstract 3
- 229910052736 halogen Inorganic materials 0.000 claims abstract 3
- 150000002367 halogens Chemical class 0.000 claims abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 claims abstract 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims 20
- 238000000034 method Methods 0.000 claims 12
- 239000002253 acid Substances 0.000 claims 10
- 239000002585 base Substances 0.000 claims 8
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 7
- SLRMQYXOBQWXCR-UHFFFAOYSA-N 2154-56-5 Chemical compound [CH2]C1=CC=CC=C1 SLRMQYXOBQWXCR-UHFFFAOYSA-N 0.000 claims 4
- 229910052783 alkali metal Inorganic materials 0.000 claims 4
- 238000006243 chemical reaction Methods 0.000 claims 4
- WCYWZMWISLQXQU-UHFFFAOYSA-N methyl Chemical compound [CH3] WCYWZMWISLQXQU-UHFFFAOYSA-N 0.000 claims 4
- 150000002366 halogen compounds Chemical class 0.000 claims 3
- 125000005843 halogen group Chemical group 0.000 claims 3
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 claims 2
- 229910000102 alkali metal hydride Inorganic materials 0.000 claims 2
- 150000008046 alkali metal hydrides Chemical class 0.000 claims 2
- 238000005904 alkaline hydrolysis reaction Methods 0.000 claims 2
- 239000000010 aprotic solvent Substances 0.000 claims 2
- 239000011230 binding agent Substances 0.000 claims 2
- 125000000753 cycloalkyl group Chemical group 0.000 claims 2
- 150000003254 radicals Chemical class 0.000 claims 2
- 239000000758 substrate Substances 0.000 claims 2
- RMRFFCXPLWYOOY-UHFFFAOYSA-N allyl radical Chemical group [CH2]C=C RMRFFCXPLWYOOY-UHFFFAOYSA-N 0.000 claims 1
- 229910000147 aluminium phosphate Inorganic materials 0.000 claims 1
- GNOIPBMMFNIUFM-UHFFFAOYSA-N hexamethylphosphoric triamide Chemical compound CN(C)P(=O)(N(C)C)N(C)C GNOIPBMMFNIUFM-UHFFFAOYSA-N 0.000 claims 1
- 239000001257 hydrogen Substances 0.000 claims 1
- 125000000467 secondary amino group Chemical group [H]N([*:1])[*:2] 0.000 claims 1
- 125000004044 trifluoroacetyl group Chemical group FC(C(=O)*)(F)F 0.000 claims 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 claims 1
- 229920002554 vinyl polymer Polymers 0.000 claims 1
- ORGHESHFQPYLAO-UHFFFAOYSA-N vinyl radical Chemical compound C=[CH] ORGHESHFQPYLAO-UHFFFAOYSA-N 0.000 claims 1
- KPPVNWGJXFMGAM-UUILKARUSA-N (e)-2-methyl-1-(6-methyl-3,4-dihydro-2h-quinolin-1-yl)but-2-en-1-one Chemical compound CC1=CC=C2N(C(=O)C(/C)=C/C)CCCC2=C1 KPPVNWGJXFMGAM-UUILKARUSA-N 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 2
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 1
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 abstract 1
- 101100294115 Caenorhabditis elegans nhr-4 gene Proteins 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 229940035676 analgesics Drugs 0.000 abstract 1
- 239000000730 antalgic agent Substances 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 238000010561 standard procedure Methods 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
- C07C217/62—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT776472A AT319916B (de) | 1972-09-11 | 1972-09-11 | Verfahren zur Herstellung von neuen basischen Äthern |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL86974B1 true PL86974B1 (en) | 1976-06-30 |
Family
ID=3599253
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL1973165129A PL86974B1 (en) | 1972-09-11 | 1973-09-10 | Basic ethers[au6018473a] |
| PL1973183330A PL92115B1 (en) | 1972-09-11 | 1973-09-10 | Basic ethers[au6018473a] |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL1973183330A PL92115B1 (en) | 1972-09-11 | 1973-09-10 | Basic ethers[au6018473a] |
Country Status (18)
-
1972
- 1972-09-11 AT AT776472A patent/AT319916B/de not_active IP Right Cessation
-
1973
- 1973-08-24 FR FR7330701A patent/FR2198740B1/fr not_active Expired
- 1973-08-27 LU LU68308A patent/LU68308A1/xx unknown
- 1973-08-29 FI FI2684/73A patent/FI56826C/fi active
- 1973-09-04 HU HUCE962A patent/HU166685B/hu unknown
- 1973-09-06 GB GB4206373A patent/GB1377350A/en not_active Expired
- 1973-09-06 CA CA180,396A patent/CA986138A/en not_active Expired
- 1973-09-10 PL PL1973165129A patent/PL86974B1/pl unknown
- 1973-09-10 CH CH835576A patent/CH590206A5/xx not_active IP Right Cessation
- 1973-09-10 ZA ZA737200*A patent/ZA737200B/xx unknown
- 1973-09-10 DD DD173374A patent/DD108521A1/xx unknown
- 1973-09-10 SE SE7312280A patent/SE413892B/xx unknown
- 1973-09-10 PL PL1973183330A patent/PL92115B1/pl unknown
- 1973-09-10 SU SU1957929A patent/SU495825A3/ru active
- 1973-09-10 BE BE135522A patent/BE804692A/xx unknown
- 1973-09-10 CH CH1294973A patent/CH596144A5/xx not_active IP Right Cessation
- 1973-09-11 RO RO7384229A patent/RO68417A/ro unknown
- 1973-09-11 CS CS736291A patent/CS203904B2/cs unknown
- 1973-09-11 ES ES418687A patent/ES418687A1/es not_active Expired
- 1973-09-11 RO RO7300076047A patent/RO63980A/ro unknown
- 1973-09-11 JP JP10176373A patent/JPS5320033B2/ja not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5320033B2 (enrdf_load_stackoverflow) | 1978-06-24 |
| CH596144A5 (enrdf_load_stackoverflow) | 1978-02-28 |
| CS203904B2 (en) | 1981-03-31 |
| AT319916B (de) | 1975-01-10 |
| BE804692A (fr) | 1974-03-11 |
| JPS4962452A (enrdf_load_stackoverflow) | 1974-06-17 |
| RO68417A (ro) | 1981-09-24 |
| FI56826B (fi) | 1979-12-31 |
| SE413892B (sv) | 1980-06-30 |
| DD108521A1 (enrdf_load_stackoverflow) | 1974-09-20 |
| FR2198740B1 (enrdf_load_stackoverflow) | 1977-01-14 |
| PL92115B1 (en) | 1977-03-31 |
| AU6018473A (en) | 1975-03-13 |
| FI56826C (fi) | 1980-04-10 |
| SU495825A3 (ru) | 1975-12-15 |
| RO63980A (fr) | 1978-08-15 |
| LU68308A1 (enrdf_load_stackoverflow) | 1973-11-23 |
| ZA737200B (en) | 1974-08-28 |
| CA986138A (en) | 1976-03-23 |
| HU166685B (enrdf_load_stackoverflow) | 1975-05-28 |
| GB1377350A (en) | 1974-12-11 |
| CH590206A5 (enrdf_load_stackoverflow) | 1977-07-29 |
| FR2198740A1 (enrdf_load_stackoverflow) | 1974-04-05 |
| ES418687A1 (es) | 1976-02-16 |
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