PL837B1 - - Google Patents
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- Publication number
- PL837B1 PL837B1 PL837A PL83722A PL837B1 PL 837 B1 PL837 B1 PL 837B1 PL 837 A PL837 A PL 837A PL 83722 A PL83722 A PL 83722A PL 837 B1 PL837 B1 PL 837B1
- Authority
- PL
- Poland
- Prior art keywords
- acid
- sodium
- methoxysulfoxylic
- water
- derivatives
- Prior art date
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- -1 sodium methoxysulfoxylic acid Chemical compound 0.000 claims description 10
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 claims description 8
- 229910000029 sodium carbonate Inorganic materials 0.000 claims description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 4
- 150000001412 amines Chemical class 0.000 claims description 3
- 238000000034 method Methods 0.000 claims description 3
- 239000002253 acid Substances 0.000 description 4
- 159000000000 sodium salts Chemical class 0.000 description 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 3
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical group C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 229910052708 sodium Inorganic materials 0.000 description 2
- 239000011734 sodium Substances 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 239000003513 alkali Substances 0.000 description 1
- RQNWIZPPADIBDY-UHFFFAOYSA-N arsenic atom Chemical class [As] RQNWIZPPADIBDY-UHFFFAOYSA-N 0.000 description 1
- 239000002585 base Substances 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 238000006386 neutralization reaction Methods 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
Description
Obecnie znane sa dwie metody dzialania pochodnych aldehydowych kwasu sulfoksy- lowego na dwuoksyarsenoianiiline.Wedlug pierwszej z nich dzialamy sola sodowa kwasu metoksysulfoksylowego na chlorowodorek zasady, wydziela sie wiec woliny kwas metoksysulfoksylowy, który dziala na pochodne arsenowe.Druga metoda stosuje ogrzewanie w ce¬ lu wywolania reakcji miedzy amina, bedaca w zawieszeniu, i sola sodowa kwasu me- toksysulfioksylowego, bez wydzielania wol¬ nego kwasu i bez obecnosci alkaljów.Ponadto nie znano jeszcze sposobu otrzy¬ mywania pochodnych dwupodstawionych bez pomocy ciepla.Dopiero wynalazek niniejiszy pozwala wy¬ tworzyc pochodne rozpuszczalne dwuoksy¬ arsenoaniliny podstawione przez sól sodowa fcwasu meitoksysulf oksylowegO' bez wyzwala¬ nia wolnego kwasu metoksysulfoksylowego i bez stosowania ogrzewania duoga oddzia¬ lywania ta sola sodowa na amine zawieszo¬ na w wodzie w obecnosci weglanu sodu; mozna w ten sposób otrzymac pochodne-je¬ dno- lub dwupodstawione w zaleznosci tyl¬ ko od ilosci wzietej do reakcji soli sodowej kwasu metoksysulfoksylowego.• Przyklad 1.Do 36 g dwuoksyarsenoaniliny, zawie¬ szonej w 150 cm* wody o temperaturze 15* dodaje sie 12 g soli sodowej kwasu metoksy¬ sulfoksylowego; roztwór alkalizujemy zapo- moca weglanu sodu w postaci stalej, lub w roztworze. Po wstrzasaniu nastepuje roz- (piuszczenie zupelne. Zwiazek arsenowy jed- oopodstawiony mozna wyosobnic badz ja¬ ko sól sodowa, która wypada jako^ osad, pozobojetnieniu kwasem octowym w alkoholu, badz. tez jako wolny kwas po dodaniu kwa¬ su chlorowodorowego. wydzielic lak samo, jak w przykladzie po¬ przednim.Przyklad 2.Do 36 g dwuoksyarsenoaniliny w 150 cm? wody o 15° O dodaje sie 25 g soli sodo¬ wej kwasu metoksysulloksylowego; roztwór alkalizuje sie przez dodanie weglanu, sodu; po wstrzasaniu nastepuje roztwarzanie.Zwiazek arsenowy dwupodstawiony mozna PLCurrently, two methods of action of sulfoxyl aldehyde derivatives on the dioxyarsenoateiline are known. According to the first method, we use sodium methoxysulfoxylic acid on the hydrochloride of the base, thus releasing methoxysulfoxylic acid which acts on arsenic derivatives. the reaction between the amine, which is in suspension, and the sodium salt of methoxysulfoxylic acid, without the evolution of free acid and without the presence of alkali. Moreover, it is not yet known how to obtain disubstituted derivatives without the aid of heat. Only the present invention allows the preparation of soluble derivatives Dioxyarsenoanilines substituted with sodium methoxysulfoxyl acid without liberation of free methoxysulfoxylic acid and without the use of heating of the large interaction of this sodium salt on an amine suspended in water in the presence of sodium carbonate; In this way, it is possible to obtain monosubstituted or disubstituted derivatives depending only on the amount taken for the reaction of the sodium salt of methoxysulfoxylic acid. Example 1 Up to 36 g of dioxyarsenaniline, suspended in 150 cm 3 of water at 15 ° C, are added 12 g of sodium methoxy sulfoxylic acid; alkalize the solution with solid sodium carbonate or in solution. Shaking is followed by complete dissolution. The monosubstituted arsenic compound can be isolated either as a sodium salt, which appears as a precipitate, after neutralization with acetic acid in alcohol, or as free acid after adding hydrochloric acid. the same as in the previous example. Example 2: To 36 g of dioxyarsenaniline in 150 cm3 of water at 15 ° C, 25 g of sodium methoxysulloxylic acid are added, the solution is made alkaline by adding sodium carbonate, reconstitution takes place after shaking. The di-substituted arsenic compound can be PL
Claims (1)
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL837B1 true PL837B1 (en) | 1924-11-29 |
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