PL48716B1 - - Google Patents
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- Publication number
- PL48716B1 PL48716B1 PL101553A PL10155363A PL48716B1 PL 48716 B1 PL48716 B1 PL 48716B1 PL 101553 A PL101553 A PL 101553A PL 10155363 A PL10155363 A PL 10155363A PL 48716 B1 PL48716 B1 PL 48716B1
- Authority
- PL
- Poland
- Prior art keywords
- phthalazine
- hydrochloride
- carboethoxyhydrazine
- ethanol
- hydrazinophthalazine
- Prior art date
Links
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 20
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims description 18
- RPTUSVTUFVMDQK-UHFFFAOYSA-N Hidralazin Chemical compound C1=CC=C2C(NN)=NN=CC2=C1 RPTUSVTUFVMDQK-UHFFFAOYSA-N 0.000 claims description 10
- RIFGWPKJUGCATF-UHFFFAOYSA-N ethyl chloroformate Chemical compound CCOC(Cl)=O RIFGWPKJUGCATF-UHFFFAOYSA-N 0.000 claims description 7
- 238000000034 method Methods 0.000 claims description 5
- OAKJQQAXSVQMHS-UHFFFAOYSA-N hydrazine Substances NN OAKJQQAXSVQMHS-UHFFFAOYSA-N 0.000 claims description 2
- VVZNYMSMDNYBQQ-UHFFFAOYSA-N phthalazin-3-ium;chloride Chemical compound Cl.C1=NN=CC2=CC=CC=C21 VVZNYMSMDNYBQQ-UHFFFAOYSA-N 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 description 4
- ZUXNZUWOTSUBMN-UHFFFAOYSA-N hydralazine hydrochloride Chemical compound Cl.C1=CC=C2C(NN)=NN=CC2=C1 ZUXNZUWOTSUBMN-UHFFFAOYSA-N 0.000 description 3
- 230000000144 pharmacologic effect Effects 0.000 description 3
- 239000000725 suspension Substances 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 238000009835 boiling Methods 0.000 description 2
- 238000009833 condensation Methods 0.000 description 2
- 230000005494 condensation Effects 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- 239000012043 crude product Substances 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- VYSYZMNJHYOXGN-UHFFFAOYSA-N ethyl n-aminocarbamate Chemical compound CCOC(=O)NN VYSYZMNJHYOXGN-UHFFFAOYSA-N 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 239000011541 reaction mixture Substances 0.000 description 1
- 239000002002 slurry Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
Priority Applications (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR973991A FR1447942A (fr) | 1963-05-11 | 1964-05-11 | Procédé de préparation de chlorhydrate de 1-carbéthoxyhydrazino-phtalazine |
| GB19565/64A GB1038548A (en) | 1963-05-11 | 1964-05-11 | A process for the preparation of 1-carboethoxyhydrazinophthalazine hydrochloride |
| BE647722D BE647722A (de) | 1963-05-11 | 1964-05-11 | |
| DE19641470165 DE1470165A1 (de) | 1963-05-11 | 1964-05-11 | Verfahren zum Herstellen von 1-Carboaethxyhydrazinophthalazin-Hydrochlorid |
| FR984817A FR4231M (de) | 1963-05-11 | 1964-08-11 | |
| CH1564764A CH481925A (de) | 1963-05-11 | 1964-12-03 | Verfahren zur Herstellung von 1-Carbäthoxy-hydrazinophthalazin-hydrochlorid |
| ES0306849A ES306849A1 (es) | 1963-05-11 | 1964-12-07 | Un procedimiento para la preparacion de clorhidrato de 1- carboetoxihidrazinoftalazina. |
| NL6414265A NL6414265A (de) | 1963-05-11 | 1964-12-08 | |
| DK603564A DK133098C (da) | 1963-05-11 | 1964-12-09 | Fremgangsmade til fremstilling af 1-carbethoxyhydrazinophthalazinhydrochlorid |
| US773977A US3591588A (en) | 1963-05-11 | 1968-10-29 | Process for the preparation of 1-carboethoxyhydrazinophthalazine hydrochloride |
| DK421975A DK134989C (da) | 1963-05-11 | 1975-09-19 | Fremgangsmade til fremstilling af 1-carbethoxyhydrazinophthalazinhydrochlorid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL48716B1 true PL48716B1 (de) | 1964-10-15 |
Family
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