PL4172199T3 - Przeciwciała wiążące protofibryle alfa-synukleiny - Google Patents
Przeciwciała wiążące protofibryle alfa-synukleinyInfo
- Publication number
- PL4172199T3 PL4172199T3 PL21765693.3T PL21765693T PL4172199T3 PL 4172199 T3 PL4172199 T3 PL 4172199T3 PL 21765693 T PL21765693 T PL 21765693T PL 4172199 T3 PL4172199 T3 PL 4172199T3
- Authority
- PL
- Poland
- Prior art keywords
- protofibrilli
- synuclein
- alpha
- binding antibodies
- antibodies
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063044881P | 2020-06-26 | 2020-06-26 | |
| US202063071150P | 2020-08-27 | 2020-08-27 | |
| PCT/IB2021/000440 WO2021260434A1 (en) | 2020-06-26 | 2021-06-25 | α-SYNUCLEIN PROTOFIBRIL-BINDING ANTIBODIES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL4172199T3 true PL4172199T3 (pl) | 2025-09-22 |
Family
ID=77627146
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL21765693.3T PL4172199T3 (pl) | 2020-06-26 | 2021-06-25 | Przeciwciała wiążące protofibryle alfa-synukleiny |
Country Status (27)
| Country | Link |
|---|---|
| US (2) | US11339212B2 (pl) |
| EP (2) | EP4172199B1 (pl) |
| JP (2) | JP7337959B2 (pl) |
| KR (1) | KR20230027095A (pl) |
| CN (1) | CN115803341A (pl) |
| AU (1) | AU2021298222A1 (pl) |
| CA (1) | CA3181207A1 (pl) |
| DK (1) | DK4172199T3 (pl) |
| ES (1) | ES3037420T3 (pl) |
| FI (1) | FI4172199T3 (pl) |
| HR (1) | HRP20250812T1 (pl) |
| HU (1) | HUE072262T2 (pl) |
| IL (1) | IL298584B2 (pl) |
| LT (1) | LT4172199T (pl) |
| MA (1) | MA60122B1 (pl) |
| MD (1) | MD4172199T2 (pl) |
| MX (1) | MX2022016005A (pl) |
| PH (1) | PH12022552829A1 (pl) |
| PL (1) | PL4172199T3 (pl) |
| PT (1) | PT4172199T (pl) |
| RS (1) | RS66984B1 (pl) |
| SI (1) | SI4172199T1 (pl) |
| SM (1) | SMT202500274T1 (pl) |
| TW (1) | TWI879983B (pl) |
| UY (1) | UY39295A (pl) |
| WO (1) | WO2021260434A1 (pl) |
| ZA (1) | ZA202211843B (pl) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI4172199T3 (fi) | 2020-06-26 | 2025-08-12 | Bioarctic Ab | Alfa-synukleiinin protofibrilliin sitoutuvat vasta-aineet |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH09502708A (ja) * | 1993-09-07 | 1997-03-18 | スミスクライン・ビーチャム・コーポレイション | Ｉｌ４により伝達される疾患の治療に有用な組み換え型ｉｌ４抗体 |
| EP1095278B1 (en) | 1998-07-03 | 2005-12-07 | Innogenetics N.V. | Differential diagnosis of neurodegeneration |
| AU2001268005A1 (en) | 2000-07-07 | 2002-01-21 | Lars Lannfelt | Prevention and treatment of alzheimer's disease |
| US20060018918A1 (en) | 2000-12-27 | 2006-01-26 | Board Of Regents, The University Of Texas System | Production of stabilized conformational isomers of disease associated proteins |
| US20080014194A1 (en) | 2003-10-31 | 2008-01-17 | Elan Pharmaceuticals, Inc. | Prevention and Treatment of Synucleinopathic and Amyloidogenic Disease |
| TW200509968A (en) | 2002-11-01 | 2005-03-16 | Elan Pharm Inc | Prevention and treatment of synucleinopathic disease |
| US8506959B2 (en) | 2002-11-01 | 2013-08-13 | Neotope Biosciences Limited | Prevention and treatment of synucleinopathic and amyloidogenic disease |
| US7358331B2 (en) | 2003-05-19 | 2008-04-15 | Elan Pharmaceuticals, Inc. | Truncated fragments of alpha-synuclein in Lewy body disease |
| WO2005047860A2 (en) | 2003-11-08 | 2005-05-26 | Elan Pharmaceuticals, Inc. | Antibodies to alpha-synuclein |
| US20050203010A1 (en) | 2003-11-14 | 2005-09-15 | Atgen Co., Ltd. | Novel peptides conferring environmental stress resistance and fusion proteins including said peptides |
| SE0401601D0 (sv) | 2004-06-21 | 2004-06-21 | Bioarctic Neuroscience Ab | Protofibril specific antibodies and uses thereof |
| WO2007089862A2 (en) | 2006-01-31 | 2007-08-09 | Elan Pharmaceuticals, Inc. | Alpha-synuclein kinase |
| BRPI0709050B1 (pt) | 2006-03-23 | 2018-12-26 | Bioarctic Neuroscience Ab | anticorpo ou fragmento do mesmo, composição, métodos para detectar protofibrilas ab in vitro, e, uso do anticorpo |
| JP5747414B2 (ja) | 2008-04-29 | 2015-07-15 | バイオアークティック ニューロサイエンス アーベー | α−シヌクレイン関連疾患についての治療および診断方法における使用のための抗体およびワクチン |
| WO2010069603A1 (en) * | 2008-12-19 | 2010-06-24 | Neurimmune Therapeutics Ag | Human anti-alpha-synuclein autoantibodies |
| PT2448968T (pt) | 2009-06-29 | 2021-04-30 | Bioarctic Ab | ANTICORPOS SELETIVOS PARA PROTOFIBRILAS/OLIGÓMEROS DE ß- AMILOIDE TRUNCADA EM N-TERMINAL |
| JP5894939B2 (ja) | 2010-02-26 | 2016-03-30 | バイオアークティック ニューロサイエンス アーベー | プロトフィブリル結合抗体ならびにパーキンソン病、レビー小体型認知症および他のα−シヌクレイノパチーの治療および診断方法におけるこれらの使用 |
| TWI560199B (en) * | 2010-08-31 | 2016-12-01 | Sanofi Sa | Peptide or peptide complex binding to α2 integrin and methods and uses involving the same |
| LT2723379T (lt) * | 2011-06-23 | 2018-10-25 | Biogen International Neuroscience Gmbh | Anti-alfa sinukleiną rišančios molekulės |
| US9534044B2 (en) * | 2013-02-28 | 2017-01-03 | United Arab Emirates University | Alpha-synuclein antibodies and uses thereof |
| CN119775416A (zh) * | 2013-12-24 | 2025-04-08 | 杨森制药公司 | 抗vista抗体及片段 |
| US11773166B2 (en) * | 2014-11-04 | 2023-10-03 | Ichnos Sciences SA | CD3/CD38 T cell retargeting hetero-dimeric immunoglobulins and methods of their production |
| JP7725185B2 (ja) * | 2015-10-06 | 2025-08-19 | アレクトル エルエルシー | 抗ｔｒｅｍ２抗体及びその使用方法 |
| FI4172199T3 (fi) | 2020-06-26 | 2025-08-12 | Bioarctic Ab | Alfa-synukleiinin protofibrilliin sitoutuvat vasta-aineet |
-
2021
- 2021-06-25 FI FIEP21765693.3T patent/FI4172199T3/fi active
- 2021-06-25 RS RS20250669A patent/RS66984B1/sr unknown
- 2021-06-25 MA MA60122A patent/MA60122B1/fr unknown
- 2021-06-25 PH PH1/2022/552829A patent/PH12022552829A1/en unknown
- 2021-06-25 EP EP21765693.3A patent/EP4172199B1/en active Active
- 2021-06-25 WO PCT/IB2021/000440 patent/WO2021260434A1/en not_active Ceased
- 2021-06-25 LT LTEPPCT/IB2021/000440T patent/LT4172199T/lt unknown
- 2021-06-25 JP JP2021570377A patent/JP7337959B2/ja active Active
- 2021-06-25 CA CA3181207A patent/CA3181207A1/en active Pending
- 2021-06-25 HR HRP20250812TT patent/HRP20250812T1/hr unknown
- 2021-06-25 KR KR1020227046153A patent/KR20230027095A/ko active Pending
- 2021-06-25 MD MDE20230490T patent/MD4172199T2/ro unknown
- 2021-06-25 CN CN202180041047.0A patent/CN115803341A/zh active Pending
- 2021-06-25 DK DK21765693.3T patent/DK4172199T3/da active
- 2021-06-25 UY UY0001039295A patent/UY39295A/es unknown
- 2021-06-25 MX MX2022016005A patent/MX2022016005A/es unknown
- 2021-06-25 AU AU2021298222A patent/AU2021298222A1/en active Pending
- 2021-06-25 TW TW110123445A patent/TWI879983B/zh active
- 2021-06-25 EP EP25168668.9A patent/EP4570315A3/en active Pending
- 2021-06-25 US US17/359,212 patent/US11339212B2/en active Active
- 2021-06-25 PL PL21765693.3T patent/PL4172199T3/pl unknown
- 2021-06-25 SI SI202130320T patent/SI4172199T1/sl unknown
- 2021-06-25 PT PT217656933T patent/PT4172199T/pt unknown
- 2021-06-25 ES ES21765693T patent/ES3037420T3/es active Active
- 2021-06-25 HU HUE21765693A patent/HUE072262T2/hu unknown
- 2021-06-25 IL IL298584A patent/IL298584B2/en unknown
- 2021-06-25 SM SM20250274T patent/SMT202500274T1/it unknown
-
2022
- 2022-04-21 US US17/726,144 patent/US20230080536A1/en not_active Abandoned
- 2022-10-31 ZA ZA2022/11843A patent/ZA202211843B/en unknown
-
2023
- 2023-08-22 JP JP2023134451A patent/JP2023159299A/ja active Pending
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