PL4126040T3 - Lipofilowe enancjomery deacetyloglukozamino–muramylodipeptydu o aktywności przeciwzapalnej i wspomagającej wzrost - Google Patents
Lipofilowe enancjomery deacetyloglukozamino–muramylodipeptydu o aktywności przeciwzapalnej i wspomagającej wzrostInfo
- Publication number
- PL4126040T3 PL4126040T3 PL21774898.7T PL21774898T PL4126040T3 PL 4126040 T3 PL4126040 T3 PL 4126040T3 PL 21774898 T PL21774898 T PL 21774898T PL 4126040 T3 PL4126040 T3 PL 4126040T3
- Authority
- PL
- Poland
- Prior art keywords
- desacetylglucosamine
- lipophilic
- enantiomers
- inflammatory
- growth promoting
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/142—Amino acids; Derivatives thereof
- A23K20/147—Polymeric derivatives, e.g. peptides or proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/5555—Muramyl dipeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Polymers & Plastics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Food Science & Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Husbandry (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
- Fodder In General (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063000364P | 2020-03-26 | 2020-03-26 | |
| PCT/US2021/024142 WO2021195372A1 (en) | 2020-03-26 | 2021-03-25 | Lipophilic enantiomers of desacetylglucosamine muramyl dipeptide with anti-inflammatory and growth promoting activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL4126040T3 true PL4126040T3 (pl) | 2025-04-28 |
Family
ID=77892334
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL21774898.7T PL4126040T3 (pl) | 2020-03-26 | 2021-03-25 | Lipofilowe enancjomery deacetyloglukozamino–muramylodipeptydu o aktywności przeciwzapalnej i wspomagającej wzrost |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP4126040B1 (pl) |
| JP (1) | JP7667177B2 (pl) |
| CN (1) | CN115605226A (pl) |
| AU (1) | AU2021241625B2 (pl) |
| BR (1) | BR112022019202A2 (pl) |
| CA (1) | CA3172936A1 (pl) |
| ES (1) | ES3014076T3 (pl) |
| MX (1) | MX2022011751A (pl) |
| NZ (1) | NZ792610A (pl) |
| PL (1) | PL4126040T3 (pl) |
| WO (1) | WO2021195372A1 (pl) |
| ZA (1) | ZA202210586B (pl) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3929293A3 (en) | 2015-04-03 | 2022-03-16 | University Of Massachusetts | Fully stabilized asymmetric sirna |
| US10633653B2 (en) | 2015-08-14 | 2020-04-28 | University Of Massachusetts | Bioactive conjugates for oligonucleotide delivery |
| EP3408391A4 (en) | 2016-01-31 | 2019-08-28 | University of Massachusetts | BRANCHED OLIGONUCLEOTIDES |
| CA3064590A1 (en) | 2017-06-23 | 2018-12-27 | University Of Massachusetts | Two-tailed self-delivering sirna and related methods |
| US11279930B2 (en) | 2018-08-23 | 2022-03-22 | University Of Massachusetts | O-methyl rich fully stabilized oligonucleotides |
| WO2020150636A1 (en) | 2019-01-18 | 2020-07-23 | University Of Massachusetts | Dynamic pharmacokinetic-modifying anchors |
| JP2022528840A (ja) | 2019-03-26 | 2022-06-16 | ユニバーシティ・オブ・マサチューセッツ | 安定性が増加した修飾オリゴヌクレオチド |
| US12024706B2 (en) | 2019-08-09 | 2024-07-02 | University Of Massachusetts | Modified oligonucleotides targeting SNPs |
| US12365894B2 (en) | 2019-09-16 | 2025-07-22 | University Of Massachusetts | Branched lipid conjugates of siRNA for specific tissue delivery |
| US12146136B2 (en) | 2020-03-26 | 2024-11-19 | University Of Massachusetts | Synthesis of modified oligonucleotides with increased stability |
| WO2024102639A1 (en) * | 2022-11-08 | 2024-05-16 | The Scripps Research Institute | N-arylpyrazole nod2 agonists as promoters of immune checkpoint inhibitor therapy |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX9301789A (es) * | 1992-04-03 | 1993-10-01 | Iaf Biochem Int | Nuevos oligopeptidos lipofilicos con actividad inmunomoduladora. |
| EP2975046A1 (en) * | 2014-07-16 | 2016-01-20 | The Provost, Fellows, Foundation Scholars, and The Other Members of Board, of The College of The Holy and Undivided Trinity of Queen Elizabeth | Novel compounds |
| US10927147B2 (en) * | 2015-12-10 | 2021-02-23 | Bharat Biotech International Limited | Muramyl peptide derivative compound, synthesis and uses thereof |
| TWI634902B (zh) | 2017-10-28 | 2018-09-11 | 醫療財團法人徐元智先生醫藥基金會亞東紀念醫院 | Use of glucosamine peptide compounds for the treatment of abnormal liver metabolism |
-
2021
- 2021-03-25 EP EP21774898.7A patent/EP4126040B1/en active Active
- 2021-03-25 MX MX2022011751A patent/MX2022011751A/es unknown
- 2021-03-25 WO PCT/US2021/024142 patent/WO2021195372A1/en not_active Ceased
- 2021-03-25 PL PL21774898.7T patent/PL4126040T3/pl unknown
- 2021-03-25 ES ES21774898T patent/ES3014076T3/es active Active
- 2021-03-25 CN CN202180038086.5A patent/CN115605226A/zh active Pending
- 2021-03-25 NZ NZ792610A patent/NZ792610A/en unknown
- 2021-03-25 BR BR112022019202A patent/BR112022019202A2/pt unknown
- 2021-03-25 AU AU2021241625A patent/AU2021241625B2/en active Active
- 2021-03-25 JP JP2022558084A patent/JP7667177B2/ja active Active
- 2021-03-25 CA CA3172936A patent/CA3172936A1/en active Pending
-
2022
- 2022-09-23 ZA ZA2022/10586A patent/ZA202210586B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP4126040B1 (en) | 2025-02-19 |
| JP2023518973A (ja) | 2023-05-09 |
| EP4126040C0 (en) | 2025-02-19 |
| JP7667177B2 (ja) | 2025-04-22 |
| MX2022011751A (es) | 2022-12-02 |
| CA3172936A1 (en) | 2021-09-30 |
| AU2021241625A1 (en) | 2022-11-10 |
| EP4126040A1 (en) | 2023-02-08 |
| ZA202210586B (en) | 2023-05-31 |
| US20230174577A1 (en) | 2023-06-08 |
| AU2021241625B2 (en) | 2025-04-24 |
| ES3014076T3 (en) | 2025-04-16 |
| NZ792610A (en) | 2025-07-25 |
| WO2021195372A1 (en) | 2021-09-30 |
| EP4126040A4 (en) | 2024-04-24 |
| CN115605226A (zh) | 2023-01-13 |
| KR20220158773A (ko) | 2022-12-01 |
| BR112022019202A2 (pt) | 2022-11-08 |
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