PL39910B1 - - Google Patents

Info

Publication number

PL39910B1

PL39910B1 PL39910A PL3991056A PL39910B1 PL 39910 B1 PL39910 B1 PL 39910B1 PL 39910 A PL39910 A PL 39910A PL 3991056 A PL3991056 A PL 3991056A PL 39910 B1 PL39910 B1 PL 39910B1

Authority

PL

Poland

Prior art keywords

sulfadine

coupling

temperature

acetyl

amino

Prior art date

1956-02-24

Links

• Espacenet
• Global Dossier
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• ASWVTGNCAZCNNR-UHFFFAOYSA-N Sulfadimidine Chemical compound CC1=CC(C)=NC(NS(=O)(=O)C=2C=CC(N)=CC=2)=N1 ASWVTGNCAZCNNR-UHFFFAOYSA-N 0.000 claims description 8
• OKTJSMMVPCPJKN-UHFFFAOYSA-N carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 7
• 239000000243 solution Substances 0.000 claims description 7
• 230000001808 coupling Effects 0.000 claims description 6
• 238000010168 coupling process Methods 0.000 claims description 6
• 238000005859 coupling reaction Methods 0.000 claims description 6
• 238000000034 method Methods 0.000 claims description 4
• JUJWROOIHBZHMG-UHFFFAOYSA-N pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 claims description 4
• CDBYLPFSWZWCQE-UHFFFAOYSA-L sodium carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 claims description 4
• KJFMBFZCATUALV-UHFFFAOYSA-N Phenolphthalein Chemical compound C1=CC(O)=CC=C1C1(C=2C=CC(O)=CC=2)C2=CC=CC=C2C(=O)O1 KJFMBFZCATUALV-UHFFFAOYSA-N 0.000 claims description 3
• LDKDGDIWEUUXSH-UHFFFAOYSA-N Thymolphthalein Chemical compound C1=C(O)C(C(C)C)=CC(C2(C3=CC=CC=C3C(=O)O2)C=2C(=CC(O)=C(C(C)C)C=2)C)=C1C LDKDGDIWEUUXSH-UHFFFAOYSA-N 0.000 claims description 3
• 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 claims description 3
• 238000002360 preparation method Methods 0.000 claims description 3
• 238000007127 saponification reaction Methods 0.000 claims description 3
• GPRYKVSEZCQIHD-UHFFFAOYSA-N 1-(4-aminophenyl)ethanone Chemical compound CC(=O)C1=CC=C(N)C=C1 GPRYKVSEZCQIHD-UHFFFAOYSA-N 0.000 claims description 2
• 239000001187 sodium carbonate Substances 0.000 claims description 2
• 229910000029 sodium carbonate Inorganic materials 0.000 claims description 2
• FAPWRFPIFSIZLT-UHFFFAOYSA-M sodium chloride Chemical class [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 2
• FDDDEECHVMSUSB-UHFFFAOYSA-N Sulfanilamide Chemical compound NC1=CC=C(S(N)(=O)=O)C=C1 FDDDEECHVMSUSB-UHFFFAOYSA-N 0.000 claims 2
• 229910052799 carbon Inorganic materials 0.000 claims 1
• XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
• HEMHJVSKTPXQMS-UHFFFAOYSA-M sodium hydroxide Inorganic materials [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 14
• 239000000047 product Substances 0.000 description 5
• VEXZGXHMUGYJMC-UHFFFAOYSA-N HCl Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 4
• XEEYBQQBJWHFJM-UHFFFAOYSA-N iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 4
• 230000015572 biosynthetic process Effects 0.000 description 3
• 238000003786 synthesis reaction Methods 0.000 description 3
• 230000002194 synthesizing Effects 0.000 description 3
• ICSNLGPSRYBMBD-UHFFFAOYSA-N 2-Aminopyridine Chemical compound NC1=CC=CC=N1 ICSNLGPSRYBMBD-UHFFFAOYSA-N 0.000 description 2
• 238000002425 crystallisation Methods 0.000 description 2
• 230000005712 crystallization Effects 0.000 description 2
• LFQSCWFLJHTTHZ-UHFFFAOYSA-N ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
• 229910052742 iron Inorganic materials 0.000 description 2
• 238000004519 manufacturing process Methods 0.000 description 2
• -1 p-amino - benzene - sulfonoamido Chemical group 0.000 description 2
• 238000000746 purification Methods 0.000 description 2
• 239000012047 saturated solution Substances 0.000 description 2
• BVKZGUZCCUSVTD-UHFFFAOYSA-N Carbonic acid Chemical compound OC(O)=O BVKZGUZCCUSVTD-UHFFFAOYSA-N 0.000 description 1
• 238000010521 absorption reaction Methods 0.000 description 1
• 229910052782 aluminium Inorganic materials 0.000 description 1
• XAGFODPZIPBFFR-UHFFFAOYSA-N aluminum Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
• QGZKDVFQNNGYKY-UHFFFAOYSA-N ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 1
• 239000004599 antimicrobial Substances 0.000 description 1
• 238000006243 chemical reaction Methods 0.000 description 1
• 238000004140 cleaning Methods 0.000 description 1
• 238000002845 discoloration Methods 0.000 description 1
• 238000010438 heat treatment Methods 0.000 description 1
• 238000009776 industrial production Methods 0.000 description 1
• 239000000543 intermediate Substances 0.000 description 1
• 230000002262 irrigation Effects 0.000 description 1
• 238000003973 irrigation Methods 0.000 description 1
• 238000002156 mixing Methods 0.000 description 1
• 230000001264 neutralization Effects 0.000 description 1
• 239000002244 precipitate Substances 0.000 description 1
• 230000008929 regeneration Effects 0.000 description 1
• 238000011069 regeneration method Methods 0.000 description 1
• KEAYESYHFKHZAL-UHFFFAOYSA-N sodium Chemical compound [Na] KEAYESYHFKHZAL-UHFFFAOYSA-N 0.000 description 1
• 229910052708 sodium Inorganic materials 0.000 description 1
• 239000011734 sodium Substances 0.000 description 1
• 239000011780 sodium chloride Substances 0.000 description 1
• 235000002639 sodium chloride Nutrition 0.000 description 1
• 239000002904 solvent Substances 0.000 description 1
• 238000003756 stirring Methods 0.000 description 1
• 150000003512 tertiary amines Chemical class 0.000 description 1