PL3842436T3 - Kompozycje farmaceutyczne zawierające imidazopirymdynę lub pochodne imidazotriazyny do zastosowania w leczeniu schizofrenii - Google Patents
Kompozycje farmaceutyczne zawierające imidazopirymdynę lub pochodne imidazotriazyny do zastosowania w leczeniu schizofreniiInfo
- Publication number
- PL3842436T3 PL3842436T3 PL20216929.8T PL20216929T PL3842436T3 PL 3842436 T3 PL3842436 T3 PL 3842436T3 PL 20216929 T PL20216929 T PL 20216929T PL 3842436 T3 PL3842436 T3 PL 3842436T3
- Authority
- PL
- Poland
- Prior art keywords
- imidazopyrimidine
- schizophrenia
- treatment
- pharmaceutical compositions
- imidazotriazine
- Prior art date
Links
- XZLIYCQRASOFQM-UHFFFAOYSA-N 5h-imidazo[4,5-d]triazine Chemical class N1=NC=C2NC=NC2=N1 XZLIYCQRASOFQM-UHFFFAOYSA-N 0.000 title 1
- KDCGOANMDULRCW-UHFFFAOYSA-N 7H-purine Chemical compound N1=CNC2=NC=NC2=C1 KDCGOANMDULRCW-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 201000000980 schizophrenia Diseases 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20150027395 | 2015-02-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3842436T3 true PL3842436T3 (pl) | 2024-03-04 |
Family
ID=56788906
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL20216929.8T PL3842436T3 (pl) | 2015-02-26 | 2016-02-25 | Kompozycje farmaceutyczne zawierające imidazopirymdynę lub pochodne imidazotriazyny do zastosowania w leczeniu schizofrenii |
| PL16755910T PL3262047T3 (pl) | 2015-02-26 | 2016-02-25 | Pochodne imidazopirymidyny i imidazotriazyny i kompozycje farmaceutyczne je zawierające |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL16755910T PL3262047T3 (pl) | 2015-02-26 | 2016-02-25 | Pochodne imidazopirymidyny i imidazotriazyny i kompozycje farmaceutyczne je zawierające |
Country Status (21)
| Country | Link |
|---|---|
| US (6) | US9745310B2 (pl) |
| EP (2) | EP3262047B1 (pl) |
| JP (1) | JP6692367B2 (pl) |
| KR (1) | KR102577178B1 (pl) |
| CN (1) | CN107635994B (pl) |
| AR (1) | AR103769A1 (pl) |
| AU (1) | AU2016224227B2 (pl) |
| BR (1) | BR112017018192B1 (pl) |
| CA (1) | CA2976422C (pl) |
| CL (1) | CL2017002163A1 (pl) |
| DK (2) | DK3842436T3 (pl) |
| ES (2) | ES2964324T3 (pl) |
| FI (1) | FI3842436T3 (pl) |
| IL (1) | IL254070B (pl) |
| MX (1) | MX381323B (pl) |
| PL (2) | PL3842436T3 (pl) |
| PT (2) | PT3262047T (pl) |
| RU (1) | RU2710556C2 (pl) |
| TW (1) | TWI713497B (pl) |
| WO (1) | WO2016137260A1 (pl) |
| ZA (1) | ZA201705333B (pl) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI713497B (zh) | 2015-02-26 | 2020-12-21 | 南韓商愛思開生物製藥股份有限公司 | 咪唑并嘧啶及咪唑并三衍生物及包含該衍生物之醫藥組成物 |
| CN114929230B (zh) * | 2019-10-21 | 2024-11-29 | 爱思开生物制药株式会社 | 咪唑并嘧啶或咪唑并三嗪化合物用于预防、减轻或治疗认知障碍或者用于改善认知功能的用途 |
| EP4049661A4 (en) * | 2019-10-21 | 2023-11-08 | SK Biopharmaceuticals Co., Ltd. | USE OF AN IMIDAZOPYRIMIDINE OR IMIDAZOTRIAZINE COMPOUND TO PREVENT, RELIEF OR TREAT DEVELOPMENTAL DISABILITIES |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4056589B2 (ja) * | 1996-07-19 | 2008-03-05 | 武田薬品工業株式会社 | 複素環化合物、その製造法および用途 |
| US6596731B2 (en) * | 2001-03-27 | 2003-07-22 | Hoffmann-La Roche Inc. | Substituted imidazo[1,2-A] pyridine derivatives |
| US7329662B2 (en) * | 2003-10-03 | 2008-02-12 | Hoffmann-La Roche Inc. | Pyrazolo-pyridine |
| EP1726585A4 (en) * | 2004-03-05 | 2009-07-15 | Banyu Pharma Co Ltd | DIARYLSUBSTITUTED FIVE-GLOSS HETEROCYCLUS DERIVAT |
| ES2340321T3 (es) * | 2005-09-27 | 2010-06-01 | F.Hoffmann-La Roche Ag | Oxadiazolilpirazolo-pirimidinas, como antagonistas de mglur2. |
| KR101532256B1 (ko) * | 2006-11-22 | 2015-06-29 | 인사이트 코포레이션 | 키나제 억제제로서의 이미다조트리아진 및 이미다조피리미딘 |
| EP2162136A4 (en) | 2007-06-03 | 2012-02-15 | Univ Vanderbilt | GLUTAMATE METABOTROPIC POSITIVE RECEPTOR-BASED ALLOSTERIC-MODULATOR BENZAMIDE DERIVATIVES (MGLUR5) AND METHODS OF MAKING AND USING THEM |
| EP2421370A4 (en) | 2009-04-23 | 2012-12-12 | Merck Sharp & Dohme | 2-alkyl-piperidine-mGluR5 receptor MODULATORS |
| AR078172A1 (es) | 2009-09-15 | 2011-10-19 | Sanofi Aventis | Fenoximetil dihidro oxazolopirimidinonas sustituidas y uso de las mismas como moduladores de receptores metabotropicos de mglur |
| RU2012116124A (ru) | 2009-09-21 | 2013-10-27 | Вандербилт Юниверсити | О-БЕНЗИЛ НИКОТИНАМИДНЫЕ АНАЛОГИ КАК ПОЗИТИВНЫЕ АЛЛОСТЕРИЧЕСКИЕ МОДУЛЯТОРЫ mGluR5 |
| CA2784768C (en) * | 2009-12-29 | 2015-02-03 | Eli Lilly And Company | Tetrahydrotriazolopyridine compounds as selective mglu5 receptor potentiators useful for the treatment of schizophrenia |
| US8785481B2 (en) * | 2010-09-29 | 2014-07-22 | Merck Sharp & Dohme Corp. | Ether benzotriazole derivatives |
| US8703946B2 (en) * | 2010-12-08 | 2014-04-22 | Vanderbilt University | Substituted pyrazolo[1,5-A]pyrazine compounds as allosteric modulators of mGluR5 receptors |
| JP2013545822A (ja) * | 2010-12-17 | 2013-12-26 | ヴァンダービルト ユニバーシティー | ｍＧｌｕＲ５受容体のアロステリック調節剤としての、二環式トリアゾールラクタムおよびピラゾールラクタム |
| PE20140236A1 (es) * | 2011-02-23 | 2014-03-14 | Pfizer | IMIDAZO[5,1-f][1,2,4]TRIAZINAS PARA EL TRATAMIENTO DE TRASTORNOS NEUROLOGICOS |
| WO2012125732A1 (en) * | 2011-03-15 | 2012-09-20 | Vanderbilt University | Substituted imadazapyrinidin-5(6h)-ones as allosteric modulators of mglur5 receptors |
| ES2790358T3 (es) * | 2011-12-28 | 2020-10-27 | Global Blood Therapeutics Inc | Compuestos de heteroaril aldehído sustituido y métodos para su uso en el aumento de la oxigenación tisular |
| US9422279B2 (en) * | 2013-03-15 | 2016-08-23 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| GB201321736D0 (en) | 2013-12-09 | 2014-01-22 | Ucb Pharma Sa | Therapeutic agents |
| TWI713497B (zh) | 2015-02-26 | 2020-12-21 | 南韓商愛思開生物製藥股份有限公司 | 咪唑并嘧啶及咪唑并三衍生物及包含該衍生物之醫藥組成物 |
-
2016
- 2016-02-23 TW TW105105245A patent/TWI713497B/zh active
- 2016-02-25 PT PT167559103T patent/PT3262047T/pt unknown
- 2016-02-25 ES ES20216929T patent/ES2964324T3/es active Active
- 2016-02-25 JP JP2017545257A patent/JP6692367B2/ja active Active
- 2016-02-25 WO PCT/KR2016/001887 patent/WO2016137260A1/en not_active Ceased
- 2016-02-25 PL PL20216929.8T patent/PL3842436T3/pl unknown
- 2016-02-25 CA CA2976422A patent/CA2976422C/en active Active
- 2016-02-25 AR ARP160100484A patent/AR103769A1/es active IP Right Grant
- 2016-02-25 PT PT202169298T patent/PT3842436T/pt unknown
- 2016-02-25 MX MX2017010630A patent/MX381323B/es unknown
- 2016-02-25 AU AU2016224227A patent/AU2016224227B2/en active Active
- 2016-02-25 EP EP16755910.3A patent/EP3262047B1/en active Active
- 2016-02-25 CN CN201680022588.8A patent/CN107635994B/zh active Active
- 2016-02-25 US US15/053,569 patent/US9745310B2/en active Active
- 2016-02-25 BR BR112017018192-4A patent/BR112017018192B1/pt active IP Right Grant
- 2016-02-25 DK DK20216929.8T patent/DK3842436T3/da active
- 2016-02-25 EP EP20216929.8A patent/EP3842436B1/en active Active
- 2016-02-25 KR KR1020160022860A patent/KR102577178B1/ko active Active
- 2016-02-25 DK DK16755910.3T patent/DK3262047T3/da active
- 2016-02-25 ES ES16755910T patent/ES2854288T3/es active Active
- 2016-02-25 PL PL16755910T patent/PL3262047T3/pl unknown
- 2016-02-25 FI FIEP20216929.8T patent/FI3842436T3/fi active
- 2016-02-25 RU RU2017131514A patent/RU2710556C2/ru active
-
2017
- 2017-07-31 US US15/664,633 patent/US10100057B2/en active Active
- 2017-08-07 ZA ZA2017/05333A patent/ZA201705333B/en unknown
- 2017-08-20 IL IL254070A patent/IL254070B/en active IP Right Grant
- 2017-08-25 CL CL2017002163A patent/CL2017002163A1/es unknown
-
2018
- 2018-09-28 US US16/146,644 patent/US20190031669A1/en not_active Abandoned
-
2020
- 2020-04-17 US US16/851,493 patent/US11046702B2/en active Active
-
2021
- 2021-06-01 US US17/335,196 patent/US12037338B2/en active Active
-
2024
- 2024-06-05 US US18/734,144 patent/US20240352023A1/en active Pending
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