PT3262047T - Derivados de imidazopirimidina e imidazotriazina e composições farmacêuticas compreendendo os mesmos - Google Patents
Derivados de imidazopirimidina e imidazotriazina e composições farmacêuticas compreendendo os mesmosInfo
- Publication number
- PT3262047T PT3262047T PT167559103T PT16755910T PT3262047T PT 3262047 T PT3262047 T PT 3262047T PT 167559103 T PT167559103 T PT 167559103T PT 16755910 T PT16755910 T PT 16755910T PT 3262047 T PT3262047 T PT 3262047T
- Authority
- PT
- Portugal
- Prior art keywords
- imidazopyrimidine
- same
- pharmaceutical composition
- imidazotriazine
- derivative
- Prior art date
Links
- XZLIYCQRASOFQM-UHFFFAOYSA-N 5h-imidazo[4,5-d]triazine Chemical class N1=NC=C2NC=NC2=N1 XZLIYCQRASOFQM-UHFFFAOYSA-N 0.000 title 1
- KDCGOANMDULRCW-UHFFFAOYSA-N 7H-purine Chemical compound N1=CNC2=NC=NC2=C1 KDCGOANMDULRCW-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20150027395 | 2015-02-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3262047T true PT3262047T (pt) | 2021-02-25 |
Family
ID=56788906
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT167559103T PT3262047T (pt) | 2015-02-26 | 2016-02-25 | Derivados de imidazopirimidina e imidazotriazina e composições farmacêuticas compreendendo os mesmos |
| PT202169298T PT3842436T (pt) | 2015-02-26 | 2016-02-25 | Composições farmacêuticas compreendendo derivados de imidazopirimidina e imidazotriazina para utilização no tratamento de esquizofrenia |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT202169298T PT3842436T (pt) | 2015-02-26 | 2016-02-25 | Composições farmacêuticas compreendendo derivados de imidazopirimidina e imidazotriazina para utilização no tratamento de esquizofrenia |
Country Status (22)
| Country | Link |
|---|---|
| US (6) | US9745310B2 (pt) |
| EP (2) | EP3262047B1 (pt) |
| JP (1) | JP6692367B2 (pt) |
| KR (1) | KR102577178B1 (pt) |
| CN (1) | CN107635994B (pt) |
| AR (1) | AR103769A1 (pt) |
| AU (1) | AU2016224227B2 (pt) |
| BR (1) | BR112017018192B1 (pt) |
| CA (1) | CA2976422C (pt) |
| CL (1) | CL2017002163A1 (pt) |
| DK (2) | DK3262047T3 (pt) |
| ES (2) | ES2964324T3 (pt) |
| FI (1) | FI3842436T3 (pt) |
| HK (1) | HK1244275A1 (pt) |
| IL (1) | IL254070B (pt) |
| MX (1) | MX2017010630A (pt) |
| PL (2) | PL3262047T3 (pt) |
| PT (2) | PT3262047T (pt) |
| RU (1) | RU2710556C2 (pt) |
| TW (1) | TWI713497B (pt) |
| WO (1) | WO2016137260A1 (pt) |
| ZA (1) | ZA201705333B (pt) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI713497B (zh) | 2015-02-26 | 2020-12-21 | 南韓商愛思開生物製藥股份有限公司 | 咪唑并嘧啶及咪唑并三衍生物及包含該衍生物之醫藥組成物 |
| WO2021080312A1 (ko) | 2019-10-21 | 2021-04-29 | 에스케이바이오팜 주식회사 | 인지 장애의 예방, 경감 또는 치료, 또는 인지 기능 향상을 위한 이미다조피리미딘 또는 이미다조트리아진 화합물의 용도 |
| JP2022552877A (ja) | 2019-10-21 | 2022-12-20 | エスケー バイオファーマスティカルズ カンパニー リミテッド | 発達障害の予防、軽減又は治療のためのイミダゾピリミジン又はイミダゾトリアジン化合物の使用 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4056589B2 (ja) * | 1996-07-19 | 2008-03-05 | 武田薬品工業株式会社 | 複素環化合物、その製造法および用途 |
| US6596731B2 (en) * | 2001-03-27 | 2003-07-22 | Hoffmann-La Roche Inc. | Substituted imidazo[1,2-A] pyridine derivatives |
| US7329662B2 (en) * | 2003-10-03 | 2008-02-12 | Hoffmann-La Roche Inc. | Pyrazolo-pyridine |
| US7902369B2 (en) * | 2004-03-05 | 2011-03-08 | Banyu Pharmaceutical Co., Ltd. | Diaryl-substituted five-membered heterocycle derivative |
| DE602006013493D1 (de) * | 2005-09-27 | 2010-05-20 | Hoffmann La Roche | Oxadiazolylpyrazolopyrimidine als mglur2-antagonisten |
| HUE026659T2 (en) * | 2006-11-22 | 2016-07-28 | Incyte Holdings Corp | Imidazotriazines and imidazopyrimidines as kinase inhibitors |
| AU2008259776A1 (en) | 2007-06-03 | 2008-12-11 | Vanderbilt University | Benzamide mGluR5 positive allosteric modulators and methods of making and using same |
| AU2010239253A1 (en) | 2009-04-23 | 2011-11-24 | Merck Sharp & Dohme Corp. | 2-alkyl piperidine mGluR5 receptor modulators |
| AR078172A1 (es) | 2009-09-15 | 2011-10-19 | Sanofi Aventis | Fenoximetil dihidro oxazolopirimidinonas sustituidas y uso de las mismas como moduladores de receptores metabotropicos de mglur |
| RU2012116124A (ru) | 2009-09-21 | 2013-10-27 | Вандербилт Юниверсити | О-БЕНЗИЛ НИКОТИНАМИДНЫЕ АНАЛОГИ КАК ПОЗИТИВНЫЕ АЛЛОСТЕРИЧЕСКИЕ МОДУЛЯТОРЫ mGluR5 |
| EP2519521B1 (en) * | 2009-12-29 | 2013-11-20 | Eli Lilly and Company | Tetrahydrotriazolopyridine compounds as selective mglu5 receptor potentiators useful for the treatment of schizophrenia |
| US8785481B2 (en) * | 2010-09-29 | 2014-07-22 | Merck Sharp & Dohme Corp. | Ether benzotriazole derivatives |
| CA2820262A1 (en) | 2010-12-08 | 2012-06-14 | Vanderbilt University | Bicyclic pyrazole compounds as allosteric modulators of mglur5 receptors |
| EP2651222A4 (en) * | 2010-12-17 | 2014-04-30 | Univ Vanderbilt | BICYCLIC TRIAZOL AND PYRAZOLLACTAME AS ALLOSTERIC MODULATORS OF MGLUR5 RECEPTORS |
| AU2012221828C1 (en) * | 2011-02-23 | 2015-10-01 | Pfizer Inc. | Imidazo[5,1-f][1,2,4]triazines for treatment of neurological disorders |
| CA2830220A1 (en) * | 2011-03-15 | 2012-09-20 | Vanderbilt University | Substituted imidazopyrimidin-5(6h)-ones as allosteric modulators of mglur5 receptors |
| US9012450B2 (en) * | 2011-12-28 | 2015-04-21 | Global Blood Therapeutics, Inc. | Substituted heteroaryl aldehyde compounds and methods for their use in increasing tissue oxygenation |
| US9422279B2 (en) * | 2013-03-15 | 2016-08-23 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| GB201321736D0 (en) | 2013-12-09 | 2014-01-22 | Ucb Pharma Sa | Therapeutic agents |
| TWI713497B (zh) | 2015-02-26 | 2020-12-21 | 南韓商愛思開生物製藥股份有限公司 | 咪唑并嘧啶及咪唑并三衍生物及包含該衍生物之醫藥組成物 |
-
2016
- 2016-02-23 TW TW105105245A patent/TWI713497B/zh active
- 2016-02-25 PT PT167559103T patent/PT3262047T/pt unknown
- 2016-02-25 MX MX2017010630A patent/MX2017010630A/es unknown
- 2016-02-25 CA CA2976422A patent/CA2976422C/en active Active
- 2016-02-25 PL PL16755910T patent/PL3262047T3/pl unknown
- 2016-02-25 AR ARP160100484A patent/AR103769A1/es active IP Right Grant
- 2016-02-25 EP EP16755910.3A patent/EP3262047B1/en active Active
- 2016-02-25 CN CN201680022588.8A patent/CN107635994B/zh active Active
- 2016-02-25 RU RU2017131514A patent/RU2710556C2/ru active
- 2016-02-25 BR BR112017018192-4A patent/BR112017018192B1/pt active IP Right Grant
- 2016-02-25 DK DK16755910.3T patent/DK3262047T3/da active
- 2016-02-25 FI FIEP20216929.8T patent/FI3842436T3/fi active
- 2016-02-25 DK DK20216929.8T patent/DK3842436T3/da active
- 2016-02-25 ES ES20216929T patent/ES2964324T3/es active Active
- 2016-02-25 PL PL20216929.8T patent/PL3842436T3/pl unknown
- 2016-02-25 AU AU2016224227A patent/AU2016224227B2/en active Active
- 2016-02-25 PT PT202169298T patent/PT3842436T/pt unknown
- 2016-02-25 WO PCT/KR2016/001887 patent/WO2016137260A1/en active Application Filing
- 2016-02-25 US US15/053,569 patent/US9745310B2/en active Active
- 2016-02-25 JP JP2017545257A patent/JP6692367B2/ja active Active
- 2016-02-25 EP EP20216929.8A patent/EP3842436B1/en active Active
- 2016-02-25 ES ES16755910T patent/ES2854288T3/es active Active
- 2016-02-25 KR KR1020160022860A patent/KR102577178B1/ko active IP Right Grant
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2017
- 2017-07-31 US US15/664,633 patent/US10100057B2/en active Active
- 2017-08-07 ZA ZA2017/05333A patent/ZA201705333B/en unknown
- 2017-08-20 IL IL254070A patent/IL254070B/en active IP Right Grant
- 2017-08-25 CL CL2017002163A patent/CL2017002163A1/es unknown
-
2018
- 2018-03-19 HK HK18103752.2A patent/HK1244275A1/zh unknown
- 2018-09-28 US US16/146,644 patent/US20190031669A1/en not_active Abandoned
-
2020
- 2020-04-17 US US16/851,493 patent/US11046702B2/en active Active
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2021
- 2021-06-01 US US17/335,196 patent/US12037338B2/en active Active
-
2024
- 2024-06-05 US US18/734,144 patent/US20240352023A1/en active Pending
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