HK1244275A1 - 咪唑並嘧啶和咪唑並三嗪衍生物和包含其的藥物組合物 - Google Patents

咪唑並嘧啶和咪唑並三嗪衍生物和包含其的藥物組合物

Info

Publication number
HK1244275A1
HK1244275A1 HK18103752.2A HK18103752A HK1244275A1 HK 1244275 A1 HK1244275 A1 HK 1244275A1 HK 18103752 A HK18103752 A HK 18103752A HK 1244275 A1 HK1244275 A1 HK 1244275A1
Authority
HK
Hong Kong
Prior art keywords
imidazopyrimidine
same
pharmaceutical composition
imidazotriazine
derivative
Prior art date
Application number
HK18103752.2A
Other languages
English (en)
Inventor
Chun Eung Park
Young Koo Jang
Yong Je Shin
Ji Yeon Kim
Seung Mo HAM
Yong Gil Kim
Hye Kyung Min
Soo Bong Cha
Hyo Jun Jung
Ju Young Lee
Seung Nam Han
Jin Yong Chung
Eun Ju Choi
Chan Mi Joung
Jong Sil Park
Ji Won Lee
Nahm Ryune Cho
Eun Ju Ryu
Cheol Young Maeng
Original Assignee
Sk Biopharmaceuticals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sk Biopharmaceuticals Co Ltd filed Critical Sk Biopharmaceuticals Co Ltd
Publication of HK1244275A1 publication Critical patent/HK1244275A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK18103752.2A 2015-02-26 2018-03-19 咪唑並嘧啶和咪唑並三嗪衍生物和包含其的藥物組合物 HK1244275A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20150027395 2015-02-26
PCT/KR2016/001887 WO2016137260A1 (en) 2015-02-26 2016-02-25 Imidazopyrimidine and imidazotriazine derivative, and pharmaceutical composition comprising the same

Publications (1)

Publication Number Publication Date
HK1244275A1 true HK1244275A1 (zh) 2018-08-03

Family

ID=56788906

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18103752.2A HK1244275A1 (zh) 2015-02-26 2018-03-19 咪唑並嘧啶和咪唑並三嗪衍生物和包含其的藥物組合物

Country Status (22)

Country Link
US (5) US9745310B2 (zh)
EP (2) EP3842436B1 (zh)
JP (1) JP6692367B2 (zh)
KR (1) KR102577178B1 (zh)
CN (1) CN107635994B (zh)
AR (1) AR103769A1 (zh)
AU (1) AU2016224227B2 (zh)
BR (1) BR112017018192B1 (zh)
CA (1) CA2976422C (zh)
CL (1) CL2017002163A1 (zh)
DK (2) DK3262047T3 (zh)
ES (2) ES2854288T3 (zh)
FI (1) FI3842436T3 (zh)
HK (1) HK1244275A1 (zh)
IL (1) IL254070B (zh)
MX (1) MX2017010630A (zh)
PL (2) PL3262047T3 (zh)
PT (2) PT3842436T (zh)
RU (1) RU2710556C2 (zh)
TW (1) TWI713497B (zh)
WO (1) WO2016137260A1 (zh)
ZA (1) ZA201705333B (zh)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114929230A (zh) * 2019-10-21 2022-08-19 爱思开生物制药株式会社 咪唑并嘧啶或咪唑并三嗪化合物用于预防、减轻或治疗认知障碍或者用于改善认知功能的用途
CA3155013A1 (en) * 2019-10-21 2021-04-29 Ki Ho Lee Use of imidazopyrimidine or imidazotriazine compound for prevention, alleviation, or treatment of developmental disability

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4056589B2 (ja) * 1996-07-19 2008-03-05 武田薬品工業株式会社 複素環化合物、その製造法および用途
US6596731B2 (en) * 2001-03-27 2003-07-22 Hoffmann-La Roche Inc. Substituted imidazo[1,2-A] pyridine derivatives
US7329662B2 (en) * 2003-10-03 2008-02-12 Hoffmann-La Roche Inc. Pyrazolo-pyridine
CA2558278A1 (en) * 2004-03-05 2005-09-15 Banyu Pharmaceutical Co., Ltd. Diaryl-substituted five-membered heterocycle derivative
KR101121292B1 (ko) * 2005-09-27 2012-04-13 에프. 호프만-라 로슈 아게 Ｍｇｌｕｒ2 길항제로서 옥사다이아졸일 피라졸로-피리미딘
HUE026659T2 (en) * 2006-11-22 2016-07-28 Incyte Holdings Corp Imidazotriazines and imidazopyrimidines as kinase inhibitors
WO2008151184A1 (en) 2007-06-03 2008-12-11 Vanderbilt University Benzamide mglur5 positive allosteric modulators and methods of making and using same
WO2010124055A1 (en) 2009-04-23 2010-10-28 Merck Sharp & Dohme Corp. 2-alkyl piperidine mglur5 receptor modulators
AR078172A1 (es) * 2009-09-15 2011-10-19 Sanofi Aventis Fenoximetil dihidro oxazolopirimidinonas sustituidas y uso de las mismas como moduladores de receptores metabotropicos de mglur
IN2012DN03322A (zh) 2009-09-21 2015-10-23 Univ Vanderbilt
JP5775094B2 (ja) * 2009-12-29 2015-09-09 イーライ リリー アンド カンパニー 統合失調症の処置に有用な選択的ｍＧｌｕ５受容体増強因子としてのテトラヒドロトリアゾロピリジン化合物
US8785481B2 (en) * 2010-09-29 2014-07-22 Merck Sharp & Dohme Corp. Ether benzotriazole derivatives
JP2013544891A (ja) 2010-12-08 2013-12-19 ヴァンダービルト ユニバーシティー ｍＧＬＵＲ５受容体のアロステリック調節剤としての二環式ピラゾール化合物
AU2011343477A1 (en) 2010-12-17 2013-07-04 Vanderbilt University Bicyclic triazole and pyrazole lactams as allosteric modulators of mGluR5 receptors
SG192576A1 (en) * 2011-02-23 2013-09-30 Pfizer IMIDAZO[5,1-f][1,2,4]TRIAZINES FOR THE TREATMENT OF NEUROLOGICAL DISORDERS
AU2012229983A1 (en) * 2011-03-15 2013-10-03 Vanderbilt University Substituted imadazapyrinidin-5(6H)-ones as allosteric modulators of mGluR5 receptors
ES2790358T3 (es) * 2011-12-28 2020-10-27 Global Blood Therapeutics Inc Compuestos de heteroaril aldehído sustituido y métodos para su uso en el aumento de la oxigenación tisular
US9422279B2 (en) * 2013-03-15 2016-08-23 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
GB201321736D0 (en) * 2013-12-09 2014-01-22 Ucb Pharma Sa Therapeutic agents

Also Published As

Publication number Publication date
CN107635994B (zh) 2019-11-05
AU2016224227A1 (en) 2017-08-31
EP3262047B1 (en) 2021-01-06
TW201639848A (zh) 2016-11-16
CN107635994A (zh) 2018-01-26
ES2854288T3 (es) 2021-09-21
RU2017131514A (ru) 2019-03-26
IL254070A0 (en) 2017-10-31
KR20160104579A (ko) 2016-09-05
US20210300933A1 (en) 2021-09-30
BR112017018192B1 (pt) 2023-11-21
EP3262047A4 (en) 2018-08-01
US10100057B2 (en) 2018-10-16
DK3262047T3 (da) 2021-03-01
US20190031669A1 (en) 2019-01-31
US11046702B2 (en) 2021-06-29
CL2017002163A1 (es) 2018-06-22
IL254070B (en) 2020-07-30
EP3262047A1 (en) 2018-01-03
WO2016137260A1 (en) 2016-09-01
PT3262047T (pt) 2021-02-25
MX2017010630A (es) 2017-11-16
US20160251361A1 (en) 2016-09-01
PL3262047T3 (pl) 2021-05-31
EP3842436B1 (en) 2023-11-08
US9745310B2 (en) 2017-08-29
CA2976422C (en) 2023-09-26
US20200277298A1 (en) 2020-09-03
ZA201705333B (en) 2019-07-31
AR103769A1 (es) 2017-05-31
TWI713497B (zh) 2020-12-21
CA2976422A1 (en) 2016-09-01
BR112017018192A2 (pt) 2018-04-17
FI3842436T3 (fi) 2024-01-24
PT3842436T (pt) 2023-12-28
AU2016224227B2 (en) 2020-01-16
JP6692367B2 (ja) 2020-05-13
DK3842436T3 (da) 2024-02-05
ES2964324T3 (es) 2024-04-05
EP3842436A1 (en) 2021-06-30
US20170349597A1 (en) 2017-12-07
JP2018506561A (ja) 2018-03-08
RU2017131514A3 (zh) 2019-05-31
KR102577178B1 (ko) 2023-09-11
PL3842436T3 (pl) 2024-03-04
RU2710556C2 (ru) 2019-12-27

Similar Documents

Publication Publication Date Title
ZA201806576B (en) Antibodies, pharmaceutical compositions and methods
IL276695B (en) Antibodies, pharmaceutical preparations and their uses
EP3364951A4 (en) NICOTINE COMPOSITION FOR VAPOTING DEVICES AND VAPOTING DEVICES USING THE SAME
HK1254654A1 (zh) 4，6-亞嘧啶基衍生物及其用途
EP3466943A4 (en) DIPHENYLAMINOPYRIMIDINE AND TRIAZINE COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF
EP3307265A4 (en) Pharmaceutical combination and uses thereof
HK1256674A1 (zh) 氘修飾的brigatinib衍生物、含有該化合物的藥物組合物及其用途
PL3421038T3 (pl) Związek naftyrydyny, kompozycja farmaceutyczna i ich zastosowanie
IL252397A0 (en) Pharmaceutical preparations, their preparation and uses
IL252897A0 (en) Indanyl compounds, pharmaceutical preparations and their medical uses
IL290114A (en) Pharmaceutical preparations, their preparation and uses
HRP20200104T8 (hr) Novi heterociklični spoj, metoda za pripremu istog, i farmaceutska kompozicija koja sadrži isto
IL248773B (en) History -6,1-Naphthyridine-5,4-Dione and pharmaceutical preparations containing them
EP3328368A4 (en) COMPOUNDS AND PHARMACEUTICAL COMPOSITION ASSOCIATED WITH UBIQUITINATION-PROTEASOME SYSTEM
LT3229843T (lt) Farmacinė kompozicija, jos paruošimo būdas ir naudojimas
SG11202002422WA (en) Novel phenylpyridine derivative and pharmaceutical composition comprising the same
IL257621B (en) A catechol derivative and a pharmaceutical preparation that includes it
HK1244275A1 (zh) 咪唑並嘧啶和咪唑並三嗪衍生物和包含其的藥物組合物
IL262929A (en) Preparations for treatment, methods for their preparation and their uses
ZA201607353B (en) Bicyclic derivatives and pharmaceutical composition including the same
HK1253369A1 (zh) 亮氨酸衍生物、包含其的組合物及其用途
AU2015902260A0 (en) Pharmaceutical Combination and Uses Thereof