PL3823971T3 - Podstawiane pochodne triazolo chinoksaliny - Google Patents

Podstawiane pochodne triazolo chinoksaliny

Info

Publication number
PL3823971T3
PL3823971T3 PL19742596.0T PL19742596T PL3823971T3 PL 3823971 T3 PL3823971 T3 PL 3823971T3 PL 19742596 T PL19742596 T PL 19742596T PL 3823971 T3 PL3823971 T3 PL 3823971T3
Authority
PL
Poland
Prior art keywords
quinoxaline derivatives
substituted triazolo
triazolo quinoxaline
substituted
derivatives
Prior art date
Application number
PL19742596.0T
Other languages
English (en)
Inventor
Florian JAKOB
Jo ALEN
Simon Lucas
Tobias CRAAN
Ingo Konetzki
Achim Kless
Stefan Schunk
Paul Ratcliffe
Sebastian Wachten
Simon Cruwys
Original Assignee
Grünenthal GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Grünenthal GmbH filed Critical Grünenthal GmbH
Publication of PL3823971T3 publication Critical patent/PL3823971T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PL19742596.0T 2018-07-20 2019-07-22 Podstawiane pochodne triazolo chinoksaliny PL3823971T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18184613 2018-07-20
PCT/EP2019/069611 WO2020016453A1 (en) 2018-07-20 2019-07-22 Substituted triazolo quinoxaline derivatives

Publications (1)

Publication Number Publication Date
PL3823971T3 true PL3823971T3 (pl) 2023-01-09

Family

ID=63014350

Family Applications (1)

Application Number Title Priority Date Filing Date
PL19742596.0T PL3823971T3 (pl) 2018-07-20 2019-07-22 Podstawiane pochodne triazolo chinoksaliny

Country Status (20)

Country Link
US (1) US20210139488A1 (pl)
EP (1) EP3823971B1 (pl)
JP (1) JP7336506B2 (pl)
CN (1) CN112673009B (pl)
AU (1) AU2019304532A1 (pl)
BR (1) BR112021000950A2 (pl)
CA (1) CA3106752A1 (pl)
DK (1) DK3823971T3 (pl)
EA (1) EA202190271A1 (pl)
ES (1) ES2929206T3 (pl)
HR (1) HRP20221020T1 (pl)
HU (1) HUE059430T2 (pl)
IL (1) IL280212B2 (pl)
LT (1) LT3823971T (pl)
MX (1) MX2021000762A (pl)
PL (1) PL3823971T3 (pl)
PT (1) PT3823971T (pl)
RS (1) RS63671B1 (pl)
SI (1) SI3823971T1 (pl)
WO (1) WO2020016453A1 (pl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI811400B (zh) * 2018-07-20 2023-08-11 德商歌林達有限公司 經進一步取代之三唑并喹噁啉衍生物
EP4090660B1 (en) * 2020-01-17 2024-01-31 Grünenthal GmbH Quinoxaline derivatives
WO2021144440A1 (en) * 2020-01-17 2021-07-22 Grünenthal GmbH Quinoxaline derivatives as modulators of the glucocorticoid receptor
CN115124471B (zh) * 2021-03-24 2024-02-13 中国工程物理研究院化工材料研究所 一类具有高能和低熔点特性的吡唑环类炸药及其合成方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994026746A1 (en) * 1993-05-06 1994-11-24 Novo Nordisk A/S [1,2,4]TRIAZOLO[4,3-a]QUINOXALINE COMPOUNDS, THEIR PREPARATION AND USE
MXPA05010293A (es) * 2003-03-27 2005-11-17 Pfizer Prod Inc 4-amino[1,2,4]triazolo[4,3-a]quinoxalinas sustituidas.
AU2004232301B2 (en) * 2003-04-23 2009-11-12 Merck Sharp & Dohme Corp. Selective spirocyclic glucocorticoid receptor modulators
BRPI0513119A (pt) 2004-07-14 2008-04-29 Ligand Pharm Inc compostos e métodos modulares de receptores intracelulares
TWI410422B (zh) 2007-01-15 2013-10-01 Mitsubishi Tanabe Pharma Corp 縮合四氫喹啉衍生物及其醫藥用途
KR20100022456A (ko) * 2007-05-29 2010-03-02 산텐 세이야꾸 가부시키가이샤 글루코코르티코이드 수용체 결합 활성을 갖는, 술폰산에스테르 또는 술폰산아미드 구조를 도입한 페닐기를 치환기로서 갖는 신규 1,2,3,4-테트라히드로퀴녹살린 유도체
JP2009046435A (ja) 2007-08-21 2009-03-05 Mitsubishi Tanabe Pharma Corp グルココルチコイド受容体モジュレーター
JP2009084273A (ja) 2007-09-13 2009-04-23 Santen Pharmaceut Co Ltd 1,3,3−トリメチル−7−フェニル−3,4−ジヒドロ−1h−キノキサリン−2−オン誘導体からなるグルココルチコイド受容体アゴニスト
WO2009103007A2 (en) 2008-02-13 2009-08-20 Ligand Pharmaceuticals Incorporated Steroid hormone receptor modulator compounds and methods
CA2996278A1 (en) * 2015-08-25 2017-03-02 Santen Pharmaceutical Co., Ltd. [4-(1,3,3-trimethyl-2-oxo-3,4-dihydro-1h-quinoxalin-7-yl)-phenoxy]ethyloxy compound or salt thereof
TWI811400B (zh) * 2018-07-20 2023-08-11 德商歌林達有限公司 經進一步取代之三唑并喹噁啉衍生物

Also Published As

Publication number Publication date
EP3823971A1 (en) 2021-05-26
WO2020016453A1 (en) 2020-01-23
CN112673009A (zh) 2021-04-16
RS63671B1 (sr) 2022-11-30
MX2021000762A (es) 2021-03-29
US20210139488A1 (en) 2021-05-13
IL280212A (en) 2021-03-01
EP3823971B1 (en) 2022-07-27
AU2019304532A1 (en) 2021-03-18
LT3823971T (lt) 2022-09-12
CN112673009B (zh) 2023-09-19
ES2929206T3 (es) 2022-11-25
JP2021532103A (ja) 2021-11-25
IL280212B2 (en) 2023-09-01
BR112021000950A2 (pt) 2021-04-20
CA3106752A1 (en) 2020-01-23
HUE059430T2 (hu) 2022-11-28
JP7336506B2 (ja) 2023-08-31
HRP20221020T1 (hr) 2022-11-11
PT3823971T (pt) 2022-10-26
SI3823971T1 (sl) 2022-10-28
EA202190271A1 (ru) 2021-06-07
DK3823971T3 (da) 2022-09-05
IL280212B1 (en) 2023-05-01

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