PL380997A1 - Krystaliczne polimorfy liganda receptora chemokiny -CXC - Google Patents

Krystaliczne polimorfy liganda receptora chemokiny -CXC

Info

Publication number
PL380997A1
PL380997A1 PL380997A PL38099705A PL380997A1 PL 380997 A1 PL380997 A1 PL 380997A1 PL 380997 A PL380997 A PL 380997A PL 38099705 A PL38099705 A PL 38099705A PL 380997 A1 PL380997 A1 PL 380997A1
Authority
PL
Poland
Prior art keywords
polymorphes
cristal
cxc
ligand
chemokine receptors
Prior art date
Application number
PL380997A
Other languages
English (en)
Inventor
Mengwei Hu
Younong Yu
Michael Dwyer
Arthur G. Taveras
Agnes Kim-Meade
Jianguo Yin
Xiaoyong Fu
Timothy Mcallister
Shuyi Zhang
Kevin Klopfer
Original Assignee
Schering Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34837390&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL380997(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Corporation filed Critical Schering Corporation
Publication of PL380997A1 publication Critical patent/PL380997A1/pl

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
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    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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    • A61P9/00—Drugs for disorders of the cardiovascular system
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Endocrinology (AREA)
  • Nutrition Science (AREA)
  • Hospice & Palliative Care (AREA)
PL380997A 2004-01-30 2005-01-28 Krystaliczne polimorfy liganda receptora chemokiny -CXC PL380997A1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US54048704P 2004-01-30 2004-01-30

Publications (1)

Publication Number Publication Date
PL380997A1 true PL380997A1 (pl) 2007-04-16

Family

ID=34837390

Family Applications (1)

Application Number Title Priority Date Filing Date
PL380997A PL380997A1 (pl) 2004-01-30 2005-01-28 Krystaliczne polimorfy liganda receptora chemokiny -CXC

Country Status (26)

Country Link
US (2) US20050192345A1 (pl)
EP (1) EP1723131B1 (pl)
JP (2) JP2007519751A (pl)
KR (1) KR100883476B1 (pl)
CN (1) CN1914187B (pl)
AR (1) AR047739A1 (pl)
AT (1) ATE478061T1 (pl)
AU (1) AU2005210504B2 (pl)
BR (1) BRPI0507329A (pl)
CA (1) CA2554709C (pl)
CO (1) CO5700731A2 (pl)
DE (1) DE602005022986D1 (pl)
EC (1) ECSP066733A (pl)
ES (1) ES2349788T3 (pl)
HK (1) HK1091496A1 (pl)
IL (1) IL177033A0 (pl)
MX (1) MXPA06008599A (pl)
MY (1) MY144657A (pl)
NO (1) NO20063841L (pl)
NZ (1) NZ548499A (pl)
PE (1) PE20051093A1 (pl)
PL (1) PL380997A1 (pl)
RU (1) RU2388756C2 (pl)
TW (1) TW200536848A (pl)
WO (1) WO2005075447A1 (pl)
ZA (1) ZA200606295B (pl)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
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US7132445B2 (en) * 2001-04-16 2006-11-07 Schering Corporation 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands
US20040106794A1 (en) 2001-04-16 2004-06-03 Schering Corporation 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands
CA2574326A1 (en) * 2004-07-22 2006-05-18 Pliva-Istrazivanje I Razvoj D.O.O. Novel form of celecoxib
GB2418427A (en) 2004-09-02 2006-03-29 Univ Cambridge Tech Ligands for G-protein coupled receptors
MX2008016016A (es) * 2006-06-12 2009-02-25 Schering Corp Formulaciones y composiciones farmaceuticas de un antagonista selectivo de cxcr2 o cxcr1 y cxcr2 y metodos para usar los mismos para tratar transtornos inflamatorios.
CN101932553A (zh) * 2007-07-03 2010-12-29 先灵公司 合成1,2-取代的3,4-二氧代-1-环丁烯化合物的方法和中间体
CA2694268A1 (en) * 2007-07-05 2009-01-08 Schering Corporation Process for controlled crystal size in 1,2-substituted 3,4-dioxo-1-cyclobutene compounds
MX2010006089A (es) * 2007-12-04 2010-09-22 Schering Corp Metodos de tratamiento de enfermedad pulmonar obstructiva cronica.
GB2455539B (en) * 2007-12-12 2012-01-18 Cambridge Entpr Ltd Anti-inflammatory compositions and combinations
UA103198C2 (en) 2008-08-04 2013-09-25 Новартис Аг Squaramide derivatives as cxcr2 antagonists
WO2010063802A1 (en) * 2008-12-05 2010-06-10 Novartis Ag 3, 4-di-substituted cyclobutene- 1, 2 -diones as cxcr2 receptor antagonists
EP2509596B1 (en) 2009-12-08 2019-08-28 Case Western Reserve University Gamma aminoacids for treating ocular disorders
WO2013030803A1 (en) 2011-09-02 2013-03-07 Novartis Ag Choline salt of an anti - inflammatory substituted cyclobutenedione compound
US8865723B2 (en) 2012-10-25 2014-10-21 Tetra Discovery Partners Llc Selective PDE4 B inhibition and improvement in cognition in subjects with brain injury
US9763992B2 (en) 2014-02-13 2017-09-19 Father Flanagan's Boys' Home Treatment of noise induced hearing loss
TWI724056B (zh) 2015-11-19 2021-04-11 美商卡默森屈有限公司 Ｃｘｃｒ２抑制劑
TWI734715B (zh) 2015-11-19 2021-08-01 美商卡默森屈有限公司 趨化因子受體調節劑
CN109152780B (zh) 2016-03-11 2021-10-01 阿迪亚生命科学公司 用于治疗结晶性关节病症的cxcr-2抑制剂
TW201919599A (zh) * 2017-09-12 2019-06-01 美商亞德生化公司 用於治療病症之cxcr-2抑制劑
CN111867579B (zh) 2018-01-08 2023-11-24 凯莫森特里克斯股份有限公司 Ccr6或cxcr2拮抗剂治疗泛发性脓疱型银屑病的方法

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US5125894A (en) * 1990-03-30 1992-06-30 Alza Corporation Method and apparatus for controlled environment electrotransport
US7027859B1 (en) * 1994-09-26 2006-04-11 Alza Corporation Electrotransport delivery device having improved safety and reduced abuse potential
DE60235507D1 (de) * 2001-04-16 2010-04-08 Pharmacopeia Llc 3,4-DI-substituierte Cyclobuten-1,2-Dione als CXC-Chemokin-Rezeptorliganden
US7132445B2 (en) * 2001-04-16 2006-11-07 Schering Corporation 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands
CN100444839C (zh) * 2002-03-18 2008-12-24 先灵公司 式(i)化合物在制备治疗化学激活物中介的疾病的药物中的应用
JP4440917B2 (ja) * 2003-04-18 2010-03-24 シェーリング コーポレイション ２−ヒドロキシ−ｎ，ｎ−ジメチル−３−［［２−（１（ｒ）−５−メチル−２−フラニル）プロピル］アミノ］−３，４−ジオキソ−１−シクロブテン−１−イル］アミノ］ベンズアミドの合成

Also Published As

Publication number Publication date
ECSP066733A (es) 2006-11-24
NZ548499A (en) 2010-06-25
NO20063841L (no) 2006-10-27
ES2349788T3 (es) 2011-01-11
US20050192345A1 (en) 2005-09-01
CO5700731A2 (es) 2006-11-30
BRPI0507329A (pt) 2007-07-03
AU2005210504B2 (en) 2009-01-08
DE602005022986D1 (de) 2010-09-30
HK1091496A1 (en) 2007-01-19
MXPA06008599A (es) 2006-08-28
US8207221B2 (en) 2012-06-26
CA2554709C (en) 2011-11-15
KR100883476B1 (ko) 2009-02-16
EP1723131A1 (en) 2006-11-22
CA2554709A1 (en) 2005-08-18
TW200536848A (en) 2005-11-16
KR20060128981A (ko) 2006-12-14
US20080279822A1 (en) 2008-11-13
RU2006131050A (ru) 2008-03-10
ZA200606295B (en) 2008-02-27
RU2388756C2 (ru) 2010-05-10
PE20051093A1 (es) 2006-01-16
CN1914187B (zh) 2012-01-25
IL177033A0 (en) 2006-12-10
ATE478061T1 (de) 2010-09-15
EP1723131B1 (en) 2010-08-18
CN1914187A (zh) 2007-02-14
AU2005210504A1 (en) 2005-08-18
JP2011042692A (ja) 2011-03-03
AR047739A1 (es) 2006-02-15
JP2007519751A (ja) 2007-07-19
MY144657A (en) 2011-10-31
WO2005075447A1 (en) 2005-08-18

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