PL380437A1 - Antagonistyczne analogi GH-RH (2003) - Google Patents

Antagonistyczne analogi GH-RH (2003)

Info

Publication number
PL380437A1
PL380437A1 PL380437A PL38043704A PL380437A1 PL 380437 A1 PL380437 A1 PL 380437A1 PL 380437 A PL380437 A PL 380437A PL 38043704 A PL38043704 A PL 38043704A PL 380437 A1 PL380437 A1 PL 380437A1
Authority
PL
Poland
Prior art keywords
antagonistic analogs
antagonistic
analogs
Prior art date
Application number
PL380437A
Other languages
English (en)
Inventor
Andrew V. Schally
Jozsef Varga
Marta Zarandi
Ren Zhi Cai
Original Assignee
Univ Tulane
Us Health
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Tulane, Us Health filed Critical Univ Tulane
Publication of PL380437A1 publication Critical patent/PL380437A1/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/60Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/06Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
PL380437A 2003-08-05 2004-07-26 Antagonistyczne analogi GH-RH (2003) PL380437A1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US49270603P 2003-08-05 2003-08-05

Publications (1)

Publication Number Publication Date
PL380437A1 true PL380437A1 (pl) 2007-01-22

Family

ID=34193144

Family Applications (1)

Application Number Title Priority Date Filing Date
PL380437A PL380437A1 (pl) 2003-08-05 2004-07-26 Antagonistyczne analogi GH-RH (2003)

Country Status (19)

Country Link
US (1) US7452865B2 (pl)
EP (1) EP1651662A4 (pl)
JP (1) JP2007526900A (pl)
KR (1) KR20060088875A (pl)
CN (1) CN1871020A (pl)
AR (1) AR049149A1 (pl)
AU (1) AU2004265280A1 (pl)
BR (1) BRPI0413257A (pl)
CA (1) CA2534436A1 (pl)
IL (1) IL173201A0 (pl)
MX (1) MXPA06001369A (pl)
NO (1) NO20061060L (pl)
PL (1) PL380437A1 (pl)
RS (1) RS20060086A (pl)
RU (1) RU2335506C2 (pl)
SG (1) SG136958A1 (pl)
TW (1) TW200517400A (pl)
WO (1) WO2005016953A2 (pl)
ZA (1) ZA200600966B (pl)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009108364A2 (en) * 2008-02-27 2009-09-03 Ipsen Pharma S.A.S. Antagonistic analogues of ghrh
US8691942B2 (en) 2008-03-28 2014-04-08 University Of Miami N- and C- terminal substituted antagonistic analogs of GH-RH
CN101983068B (zh) * 2008-03-28 2014-12-24 迈阿密大学 N末端和c末端取代的人gh-rh拮抗类似物
US8796216B2 (en) 2008-06-12 2014-08-05 Syntaxin Limited Suppression of neuroendocrine diseases
JP5799397B2 (ja) * 2008-06-12 2015-10-28 イプセン・バイオイノベーション・リミテッドIpsen Bioinnovation Limited 癌の抑制
EP2719392B1 (en) * 2008-06-12 2019-07-24 Ipsen Bioinnovation Limited Fusion proteins for use in the treatment of acromegaly
US8227421B2 (en) * 2009-09-17 2012-07-24 University Of Miami Fluorinated GHRH antagonists
WO2011153491A2 (en) 2010-06-03 2011-12-08 University Of Miami Agonists of growth hormone releasing hormone as effectors for survival and proliferation of pancreatic islets
KR20140027284A (ko) 2011-04-21 2014-03-06 쎄러테크놀로지스 인코포레이티드 성장 호르몬 방출 인자(grf) 유사체 및 이의 용도
US9079974B2 (en) * 2011-12-21 2015-07-14 The University Of Miami GH-RH analogs with potent agonistic effects
EP2866894A4 (en) * 2012-06-27 2016-03-16 Univ Miami COMPOSITION AND METHOD FOR THE TREATMENT OF MORBUS ALZHEIMER
EP2934565B1 (en) 2012-12-21 2019-03-13 University of Miami Ghrh agonists for the treatment of ischemic disorders
WO2014100816A2 (en) 2012-12-21 2014-06-26 University Of Miami Ghrh agonists for islet cell transplantation and function and the treatment of diabetes
WO2020163833A2 (en) 2019-02-08 2020-08-13 United States Government As Represented By The Department Of Veterans Affairs Growth hormone-releasing hormone antagonists and uses thereof
WO2021222129A1 (en) 2020-04-27 2021-11-04 The University Of Miami Method of treating an inflammatory disorder
CN114195881B (zh) * 2021-12-16 2022-09-16 浙江湃肽生物股份有限公司 一种制备醋酸舍莫瑞林的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5942489A (en) * 1996-05-03 1999-08-24 The Administrators Of The Tulane Educational Fund HGH-RH(1-29)NH2 analogues having antagonistic activity
US6057422A (en) * 1998-11-25 2000-05-02 The Administrators Of The Tulane Educational Fund Antagonistic analogs of GH-RH inhibiting IGF-I and -II

Also Published As

Publication number Publication date
RS20060086A (en) 2008-08-07
WO2005016953A2 (en) 2005-02-24
CN1871020A (zh) 2006-11-29
BRPI0413257A (pt) 2006-10-03
ZA200600966B (en) 2007-05-30
RU2335506C2 (ru) 2008-10-10
NO20061060L (no) 2006-05-03
EP1651662A2 (en) 2006-05-03
IL173201A0 (en) 2006-06-11
US7452865B2 (en) 2008-11-18
AR049149A1 (es) 2006-07-05
JP2007526900A (ja) 2007-09-20
AU2004265280A1 (en) 2005-02-24
MXPA06001369A (es) 2007-02-19
EP1651662A4 (en) 2009-07-01
KR20060088875A (ko) 2006-08-07
US20070042950A1 (en) 2007-02-22
RU2006106701A (ru) 2007-09-20
SG136958A1 (en) 2007-11-29
WO2005016953A3 (en) 2006-02-09
TW200517400A (en) 2005-06-01
CA2534436A1 (en) 2005-02-24

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Legal Events

Date Code Title Description
DISC Decisions on discontinuance of the proceedings (taken after the publication of the particulars of the applications)