PL378291A1 - Wytwarzanie komórek dendrytycznych z monocytarnych prekursorów komórek dendrytycznych z zastosowaniem GM-CSF w nieobecności dodatkowych cytokin - Google Patents

Wytwarzanie komórek dendrytycznych z monocytarnych prekursorów komórek dendrytycznych z zastosowaniem GM-CSF w nieobecności dodatkowych cytokin

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Publication number
PL378291A1
PL378291A1 PL378291A PL37829104A PL378291A1 PL 378291 A1 PL378291 A1 PL 378291A1 PL 378291 A PL378291 A PL 378291A PL 37829104 A PL37829104 A PL 37829104A PL 378291 A1 PL378291 A1 PL 378291A1
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Poland
Prior art keywords
cells
csf
dendritic
monocytes
dendritic cells
Prior art date
Application number
PL378291A
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English (en)
Other versions
PL209998B1 (pl
Inventor
Benjamin A. Tjoa
Marnix L. Bosch
Original Assignee
Northwest Biotherapeutics, Inc.
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Publication date
Application filed by Northwest Biotherapeutics, Inc. filed Critical Northwest Biotherapeutics, Inc.
Publication of PL378291A1 publication Critical patent/PL378291A1/pl
Publication of PL209998B1 publication Critical patent/PL209998B1/pl

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    • C—CHEMISTRY; METALLURGY
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    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0639—Dendritic cells, e.g. Langherhans cells in the epidermis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/70—Undefined extracts
    • C12N2500/72—Undefined extracts from bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/22—Colony stimulating factors (G-CSF, GM-CSF)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/24—Interferons [IFN]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/70—Non-animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/10—Mineral substrates
    • C12N2533/12—Glass

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
PL378291A 2003-02-27 2004-02-27 Sposób in vitro lub ex vivo różnicowania monocytarnych prekursorów komórek dendrytycznych w niedojrzale komórki dendrytyczne PL209998B1 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45101503P 2003-02-27 2003-02-27
PCT/US2004/006119 WO2004076651A2 (en) 2003-02-27 2004-02-27 Generation of dendritic cells from monocytic dendritic precursor cells with gm-csf in the absence of additional cytokines

Publications (2)

Publication Number Publication Date
PL378291A1 true PL378291A1 (pl) 2006-03-20
PL209998B1 PL209998B1 (pl) 2011-11-30

Family

ID=32927693

Family Applications (1)

Application Number Title Priority Date Filing Date
PL378291A PL209998B1 (pl) 2003-02-27 2004-02-27 Sposób in vitro lub ex vivo różnicowania monocytarnych prekursorów komórek dendrytycznych w niedojrzale komórki dendrytyczne

Country Status (20)

Country Link
US (4) US8389278B2 (pl)
EP (1) EP1604016B1 (pl)
JP (1) JP4762887B2 (pl)
KR (2) KR20110106474A (pl)
CN (1) CN1784488B (pl)
AT (1) ATE420946T1 (pl)
AU (2) AU2004214896A1 (pl)
BR (1) BRPI0407900A (pl)
CA (1) CA2517295C (pl)
CY (1) CY1109099T1 (pl)
DE (1) DE602004019057D1 (pl)
DK (1) DK1604016T3 (pl)
ES (1) ES2321939T3 (pl)
IL (1) IL170512A (pl)
MX (1) MXPA05009178A (pl)
NZ (1) NZ542071A (pl)
PL (1) PL209998B1 (pl)
RU (1) RU2364625C2 (pl)
TW (1) TW200506061A (pl)
WO (1) WO2004076651A2 (pl)

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US7939090B2 (en) * 2003-10-21 2011-05-10 Cedars-Sinai Medical Center System and method for the treatment of cancer, including cancers of the central nervous system
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US8129184B2 (en) * 2006-09-26 2012-03-06 Cedars-Sinai Medical Center Cancer stem cell antigen vaccines and methods
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AU2010307075B2 (en) 2009-10-12 2014-12-18 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Granulysin in immunotherapy
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JP5577472B2 (ja) * 2012-02-10 2014-08-20 医療法人社団博心厚生会 単球増殖剤、単球増殖用培地、単球の製造方法、樹状細胞の製造方法、及び樹状細胞ワクチンの製造方法
US20140234351A1 (en) 2013-02-14 2014-08-21 Immunocellular Therapeutics, Ltd. Cancer vaccines and vaccination methods
WO2016011878A1 (zh) * 2014-07-23 2016-01-28 国家纳米科学中心 一种抑制肿瘤转移和治疗白血病的多肽和多肽复合物、其制备方法及其应用
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Also Published As

Publication number Publication date
JP4762887B2 (ja) 2011-08-31
ES2321939T3 (es) 2009-06-15
US20040203143A1 (en) 2004-10-14
US20210102169A1 (en) 2021-04-08
EP1604016B1 (en) 2009-01-14
CA2517295A1 (en) 2004-09-10
CN1784488B (zh) 2010-07-28
NZ542071A (en) 2007-11-30
US20130273654A1 (en) 2013-10-17
AU2004214896A1 (en) 2004-09-10
KR20050107471A (ko) 2005-11-11
DK1604016T3 (da) 2009-05-18
RU2005129561A (ru) 2006-03-10
US11827903B2 (en) 2023-11-28
KR101201875B1 (ko) 2012-11-15
HK1086597A1 (en) 2006-09-22
ATE420946T1 (de) 2009-01-15
MXPA05009178A (es) 2006-03-08
US20160024472A1 (en) 2016-01-28
US9102917B2 (en) 2015-08-11
IL170512A (en) 2013-12-31
TW200506061A (en) 2005-02-16
EP1604016A4 (en) 2006-03-08
CY1109099T1 (el) 2014-07-02
KR20110106474A (ko) 2011-09-28
JP2006519021A (ja) 2006-08-24
DE602004019057D1 (de) 2009-03-05
BRPI0407900A (pt) 2006-03-21
WO2004076651A3 (en) 2005-03-10
EP1604016A2 (en) 2005-12-14
RU2364625C2 (ru) 2009-08-20
US8389278B2 (en) 2013-03-05
WO2004076651A2 (en) 2004-09-10
AU2010201319A1 (en) 2010-04-29
CN1784488A (zh) 2006-06-07
AU2010201319B2 (en) 2012-09-06
US10731130B2 (en) 2020-08-04
PL209998B1 (pl) 2011-11-30
CA2517295C (en) 2016-01-12

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