ATE420946T1 - Erzeugung dendritischer zellen aus monozytischen dendritischen vorläuferzellen mit gm-csf ohne anwesenheit zusätzlicher zytokine - Google Patents
Erzeugung dendritischer zellen aus monozytischen dendritischen vorläuferzellen mit gm-csf ohne anwesenheit zusätzlicher zytokineInfo
- Publication number
- ATE420946T1 ATE420946T1 AT04715780T AT04715780T ATE420946T1 AT E420946 T1 ATE420946 T1 AT E420946T1 AT 04715780 T AT04715780 T AT 04715780T AT 04715780 T AT04715780 T AT 04715780T AT E420946 T1 ATE420946 T1 AT E420946T1
- Authority
- AT
- Austria
- Prior art keywords
- cells
- csf
- monocytes
- dendritic
- dendritic cells
- Prior art date
Links
- 102000004457 Granulocyte-Macrophage Colony-Stimulating Factor Human genes 0.000 title abstract 4
- 108010017213 Granulocyte-Macrophage Colony-Stimulating Factor Proteins 0.000 title abstract 4
- 108090000695 Cytokines Proteins 0.000 title abstract 3
- 102000004127 Cytokines Human genes 0.000 title abstract 3
- 239000002243 precursor Substances 0.000 title 1
- 210000004443 dendritic cell Anatomy 0.000 abstract 5
- 210000001616 monocyte Anatomy 0.000 abstract 4
- 108090000978 Interleukin-4 Proteins 0.000 abstract 2
- 230000004913 activation Effects 0.000 abstract 2
- 210000004027 cell Anatomy 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 230000004069 differentiation Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000009169 immunotherapy Methods 0.000 abstract 1
- 230000035800 maturation Effects 0.000 abstract 1
- 210000005259 peripheral blood Anatomy 0.000 abstract 1
- 239000011886 peripheral blood Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0639—Dendritic cells, e.g. Langherhans cells in the epidermis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/70—Undefined extracts
- C12N2500/72—Undefined extracts from bacteria
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/22—Colony stimulating factors (G-CSF, GM-CSF)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/24—Interferons [IFN]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/70—Non-animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/10—Mineral substrates
- C12N2533/12—Glass
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45101503P | 2003-02-27 | 2003-02-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE420946T1 true ATE420946T1 (de) | 2009-01-15 |
Family
ID=32927693
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04715780T ATE420946T1 (de) | 2003-02-27 | 2004-02-27 | Erzeugung dendritischer zellen aus monozytischen dendritischen vorläuferzellen mit gm-csf ohne anwesenheit zusätzlicher zytokine |
Country Status (20)
| Country | Link |
|---|---|
| US (4) | US8389278B2 (de) |
| EP (1) | EP1604016B1 (de) |
| JP (1) | JP4762887B2 (de) |
| KR (2) | KR20110106474A (de) |
| CN (1) | CN1784488B (de) |
| AT (1) | ATE420946T1 (de) |
| AU (2) | AU2004214896A1 (de) |
| BR (1) | BRPI0407900A (de) |
| CA (1) | CA2517295C (de) |
| CY (1) | CY1109099T1 (de) |
| DE (1) | DE602004019057D1 (de) |
| DK (1) | DK1604016T3 (de) |
| ES (1) | ES2321939T3 (de) |
| IL (1) | IL170512A (de) |
| MX (1) | MXPA05009178A (de) |
| NZ (1) | NZ542071A (de) |
| PL (1) | PL209998B1 (de) |
| RU (1) | RU2364625C2 (de) |
| TW (1) | TW200506061A (de) |
| WO (1) | WO2004076651A2 (de) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040057935A1 (en) * | 2002-09-20 | 2004-03-25 | Cedars-Sinai Medical Center | Intratumoral delivery of dendritic cells |
| EP2260861A1 (de) * | 2002-12-06 | 2010-12-15 | NorthWest Biotherapeutics, Inc. | Verabreichung teilgereifter dendritischer Zellen in vitro zur Behandlung von Tumoren |
| EP1670513B1 (de) * | 2003-10-06 | 2013-01-23 | Cedars-Sinai Medical Center | Cox-2-inhibitoren und dendritische zellen zur verwendung in der krebsbehandlung |
| US7939090B2 (en) * | 2003-10-21 | 2011-05-10 | Cedars-Sinai Medical Center | System and method for the treatment of cancer, including cancers of the central nervous system |
| US7790039B2 (en) | 2003-11-24 | 2010-09-07 | Northwest Biotherapeutics, Inc. | Tangential flow filtration devices and methods for stem cell enrichment |
| KR20150032915A (ko) | 2005-04-08 | 2015-03-30 | 아르고스 쎄라퓨틱스 인코포레이티드 | 수지상 세포 조성물 및 방법 |
| CA2632263C (en) * | 2005-12-08 | 2022-01-11 | Northwest Biotherapeutics, Inc. | Compositions and methods for inducing the activation of immature monocytic dendritic cells |
| EP1806395A1 (de) * | 2006-01-06 | 2007-07-11 | Stichting Sanquin Bloedvoorziening | Maturation von dendritischen Zellen |
| US8129184B2 (en) * | 2006-09-26 | 2012-03-06 | Cedars-Sinai Medical Center | Cancer stem cell antigen vaccines and methods |
| US8871211B2 (en) | 2006-09-28 | 2014-10-28 | Cedars-Sinai Medical Center | Cancer vaccines and vaccination methods |
| EP1920782A1 (de) * | 2006-11-10 | 2008-05-14 | Glycotope Gmbh | Mikroorganismen oder deren Fraktionen fähig zur Aktivierung von Zelleimmunität gegen Kohlenhydrate |
| KR100896747B1 (ko) | 2007-05-30 | 2009-05-11 | 동아대학교 산학협력단 | 후코이단 또는 그 유사체를 함유하는 수지상 세포의 성숙화유도용 조성물 |
| WO2009155332A1 (en) * | 2008-06-17 | 2009-12-23 | Cedars-Sinai Medical Center | Use of toll-like receptor ligands as adjuvants to vaccination therapy for brain tumors |
| PL2328923T3 (pl) * | 2008-09-02 | 2016-06-30 | Cedars Sinai Medical Center | Epitopy CD133 |
| JP2010063404A (ja) * | 2008-09-10 | 2010-03-25 | Olympus Corp | 幹細胞の分離方法 |
| FR2940451B1 (fr) * | 2008-12-18 | 2014-09-12 | Proteus | Procede d'evaluation de l'immunogenicite des proteines |
| ES2618573T3 (es) | 2009-05-07 | 2017-06-21 | ImmunoCellular Therapeutics,Ltd | Epítopos de CD133 |
| ES2711504T3 (es) * | 2009-07-24 | 2019-05-06 | Rhode Island Hospital | Vacunas de células dendríticas para tumores que expresan asparaginil-beta-hidroxilasa |
| AU2010307075B2 (en) | 2009-10-12 | 2014-12-18 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Granulysin in immunotherapy |
| RU2575978C2 (ru) * | 2010-03-15 | 2016-02-27 | Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания | Система и способ получения и хранения активированных зрелых дендритных клеток |
| RU2458985C1 (ru) * | 2011-03-18 | 2012-08-20 | Федеральное государственное бюджетное учреждение "Научно-исследовательский институт клинической иммунологии" Сибирского отделения Российской академии медицинских наук (ФГБУ "НИИКИ" СО РАМН) | Способ генерации антиген-специфических цитотоксических клеток с противоопухолевой активностью |
| JP5577472B2 (ja) * | 2012-02-10 | 2014-08-20 | 医療法人社団博心厚生会 | 単球増殖剤、単球増殖用培地、単球の製造方法、樹状細胞の製造方法、及び樹状細胞ワクチンの製造方法 |
| US20140234351A1 (en) | 2013-02-14 | 2014-08-21 | Immunocellular Therapeutics, Ltd. | Cancer vaccines and vaccination methods |
| WO2016011878A1 (zh) * | 2014-07-23 | 2016-01-28 | 国家纳米科学中心 | 一种抑制肿瘤转移和治疗白血病的多肽和多肽复合物、其制备方法及其应用 |
| CN104098652B (zh) * | 2014-07-23 | 2016-11-09 | 国家纳米科学中心 | 一种抑制肿瘤转移的多肽和多肽复合物、其制备方法及其应用 |
| JP6985939B2 (ja) * | 2015-06-30 | 2021-12-22 | ノースウエスト バイオセラピューティクス，インコーポレイティド | 改善または増大した抗腫瘍免疫応答を誘導する最適に活性化された樹状細胞 |
| EP3350318B1 (de) | 2015-09-15 | 2022-04-13 | NorthWest Biotherapeutics, Inc. | Verfahren im zusammenhang mit aktivierten dendritischen zellzusammensetzungen für personen mit fortgeschrittenen krebserkrankungen |
| CN105483084A (zh) * | 2016-01-04 | 2016-04-13 | 英普乐孚生物技术(上海)有限公司 | 肿瘤抗原靶向性dc细胞的制备方法 |
| US12239666B2 (en) | 2018-06-19 | 2025-03-04 | H. Lee Moffitt Cancer Center And Research Institute, Inc. Inc. | Oncolytic virus or antigen presenting cell mediated cancer therapy using type I interferon and CD40-ligand |
| KR102159766B1 (ko) * | 2018-11-12 | 2020-09-24 | 조선대학교산학협력단 | 홍조류추출물을 이용한 미성숙수지상세포 분화유도용 배지조성물 및 미성숙수지상세포 분화유도방법 |
| IL286907B2 (en) * | 2019-04-03 | 2025-11-01 | Akron Bioproducts Llc | Cryopreservation and cell culture media |
| WO2021010344A1 (ja) * | 2019-07-12 | 2021-01-21 | 国立大学法人九州大学 | 心筋収縮改善治療法および心筋細胞死抑制法の開発 |
| BR112022009560A2 (pt) * | 2019-11-18 | 2022-08-02 | Childrens Medical Center | Células dendríticas hiperativas possibilitam imunidade antitumoral baseada na transferência de células adotivas duráveis |
| KR102904431B1 (ko) * | 2021-05-07 | 2025-12-26 | (주)나노팬텍 | 수지상 세포의 배양 방법 |
| US20240207308A1 (en) * | 2021-05-07 | 2024-06-27 | NANOFAENTECH CO., Ltd. | Method for culturing dendritic cells |
| CN113881632B (zh) * | 2021-09-29 | 2023-09-29 | 四川省医学科学院·四川省人民医院 | 一种提高dc细胞活性的细胞培养基及培养方法 |
| US20230227780A1 (en) * | 2022-01-20 | 2023-07-20 | 3T Biosciences, Inc. | T cell receptor (tcr) compositions and methods for optimizing antigen reactive t-cells |
| US12584107B2 (en) * | 2022-01-20 | 2026-03-24 | 3T Biosciences, Inc. | T cell receptor (TCR) compositions and methods for optimizing antigen reactive T-cells |
| GB2624871A (en) * | 2022-11-29 | 2024-06-05 | Alv B As | Process for preparing a population of dendritic cells and immunotherapy using the same |
| CN118389430A (zh) * | 2024-04-12 | 2024-07-26 | 广东壹加再生医学研究院有限公司 | 一种高抗肿瘤特异性dc-cik细胞的制备方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3683956D1 (de) * | 1985-06-11 | 1992-04-02 | Us Commerce | In einem serumfreien medium in suspension kultivierte humane monozyten. |
| US5162504A (en) | 1988-06-03 | 1992-11-10 | Cytogen Corporation | Monoclonal antibodies to a new antigenic marker in epithelial prostatic cells and serum of prostatic cancer patients |
| DE69333433T2 (de) | 1992-04-01 | 2004-12-02 | The Rockefeller University | Verfahren zur in vitro kultivierung dendritischer vorläuferzellen und deren verwendung zur immunogen herstellung |
| US6010905A (en) * | 1995-01-27 | 2000-01-04 | The United States Of America As Represented By The Department Of Health & Human Services | Method for inducing monocytes to exhibit the phenotype of activated myeloid dendritic cells |
| US5788963A (en) | 1995-07-31 | 1998-08-04 | Pacific Northwest Cancer Foundation | Isolation and/or preservation of dendritic cells for prostate cancer immunotherapy |
| US7659119B2 (en) * | 1996-02-12 | 2010-02-09 | Argos Therapeutics, Inc. | Method and compositions for obtaining mature dendritic cells |
| US20020094545A1 (en) | 2000-11-30 | 2002-07-18 | Harris Paul E. | Growth of human dendritic cells for cancer immunotherapy in closed system using microcarrier beads |
| WO2003010292A2 (en) * | 2001-07-25 | 2003-02-06 | Northwest Biotherapeutics, Inc. | Methods and apparatus for enrichment and culture of monocytic dendritic cell precursors |
| EP2322603B1 (de) * | 2001-09-06 | 2019-10-16 | NorthWest Biotherapeutics, Inc. | Zusammensetzungen und Verfahren für die Aktivierung von monocytischen Dendritischen Zellen und T-Zellen auf Th1-Antwort |
| AU2003243673B2 (en) * | 2002-06-19 | 2010-01-21 | Northwest Biotherapeutics, Inc. | Tangential flow filtration devices and methods for leukocyte enrichment |
| CN1761744A (zh) * | 2003-02-10 | 2006-04-19 | 西北生物治疗药物公司 | 培养的cd14+抗原呈递细胞 |
-
2004
- 2004-02-27 ES ES04715780T patent/ES2321939T3/es not_active Expired - Lifetime
- 2004-02-27 TW TW093105079A patent/TW200506061A/zh unknown
- 2004-02-27 WO PCT/US2004/006119 patent/WO2004076651A2/en not_active Ceased
- 2004-02-27 CN CN2004800105421A patent/CN1784488B/zh not_active Expired - Fee Related
- 2004-02-27 US US10/789,807 patent/US8389278B2/en not_active Expired - Fee Related
- 2004-02-27 KR KR1020117021421A patent/KR20110106474A/ko not_active Ceased
- 2004-02-27 RU RU2005129561/13A patent/RU2364625C2/ru active
- 2004-02-27 NZ NZ542071A patent/NZ542071A/en not_active IP Right Cessation
- 2004-02-27 MX MXPA05009178A patent/MXPA05009178A/es active IP Right Grant
- 2004-02-27 AU AU2004214896A patent/AU2004214896A1/en not_active Abandoned
- 2004-02-27 AT AT04715780T patent/ATE420946T1/de not_active IP Right Cessation
- 2004-02-27 DK DK04715780T patent/DK1604016T3/da active
- 2004-02-27 KR KR1020057016059A patent/KR101201875B1/ko not_active Expired - Fee Related
- 2004-02-27 JP JP2006503922A patent/JP4762887B2/ja not_active Expired - Fee Related
- 2004-02-27 DE DE602004019057T patent/DE602004019057D1/de not_active Expired - Lifetime
- 2004-02-27 CA CA2517295A patent/CA2517295C/en not_active Expired - Lifetime
- 2004-02-27 BR BRPI0407900-0A patent/BRPI0407900A/pt not_active Application Discontinuation
- 2004-02-27 EP EP04715780A patent/EP1604016B1/de not_active Expired - Lifetime
- 2004-02-27 PL PL378291A patent/PL209998B1/pl unknown
-
2005
- 2005-08-25 IL IL170512A patent/IL170512A/en active IP Right Grant
-
2009
- 2009-04-14 CY CY20091100437T patent/CY1109099T1/el unknown
-
2010
- 2010-04-01 AU AU2010201319A patent/AU2010201319B2/en not_active Ceased
-
2013
- 2013-03-05 US US13/786,208 patent/US9102917B2/en not_active Expired - Lifetime
-
2015
- 2015-07-30 US US14/814,315 patent/US10731130B2/en not_active Expired - Fee Related
-
2020
- 2020-08-03 US US16/983,300 patent/US11827903B2/en not_active Expired - Lifetime
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE602004019057D1 (de) | Erzeugung dendritischer zellen aus monozytischen dendritischen vorläuferzellen mit gm-csf ohne anwesenheit zusätzlicher zytokine | |
| Santini et al. | The natural alliance between type I interferon and dendritic cells and its role in linking innate and adaptive immunity | |
| Laskarin et al. | Antigen‐presenting cells and materno‐fetal tolerance: an emerging role for dendritic cells | |
| Kadowaki | Dendritic cells—a conductor of T cell differentiation— | |
| Collins et al. | Retinoic acid attenuates ileitis by restoring the balance between T-helper 17 and T regulatory cells | |
| BRPI0212545B8 (pt) | método ex vivo ou in vitro para produzir uma população de célula dendrítica madura e método para produzir células t | |
| JP2008535493A5 (de) | ||
| Gregori | Dendritic cells in networks of immunological tolerance | |
| RU2008122550A (ru) | Композиции и способы индуцирования активации незрелых моноцитарных дендритных клеток | |
| ATE525908T1 (de) | Einstufiges schnellverfahren zurherstellung eines antigenbeladenen dendritenzellimpfstoffs aus vorstufen | |
| EP1997884A1 (de) | Neuartige menschliche t-zellenpopulation | |
| Jegatheeswaran et al. | Searching for the elusive regulatory innate lymphoid cell | |
| Lim et al. | Principal role of IL-12p40 in the decreased Th1 and Th17 responses driven by dendritic cells of mice lacking IL-12 and IL-18 | |
| Ingelsten et al. | Rapid increase of interleukin-10 plasma levels after combined auxiliary liver-kidney transplantation in presensitized patients | |
| AR128929A1 (es) | Composiciones y métodos para activar células inmunitarias | |
| CN116004533A (zh) | iNKT细胞的激活扩增方法及其培养基组合 | |
| Holtick et al. | Impact of psoralen/UVA-treatment on survival, activation, and immunostimulatory capacity of monocyte-derived dendritic cells | |
| Son et al. | Prostaglandin E2 is a negative regulator on human plasmacytoid dendritic cells | |
| Mariotti et al. | T‐cell‐mediated and antigen‐dependent differentiation of human monocyte into different dendritic cell subsets: a feedback control of Th1/Th2 responses | |
| Pizzurro et al. | Cytokine-enhanced maturation and migration to the lymph nodes of a human dying melanoma cell-loaded dendritic cell vaccine | |
| O'Connell et al. | Type‐1 polarized nature of mouse liver CD8α–and CD8α+ dendritic cells: tissue‐dependent differences offset CD8α‐related dendritic cell heterogeneity | |
| Ghaedi et al. | Different Doses of Transforming Growth Factor-β on In vitro Differentiation of Human Naïve CD4+ T Cells to T Helper 17 | |
| DE60130206D1 (de) | Zusammensetzungen und verfahren zur herstellung von antigen-präsentierenden zellen | |
| Pazmandi et al. | Modulatory effects of low-dose hydrogen peroxide on the function of human plasmacytoid dendritic cells | |
| GanjiBakhsh et al. | Mixture of fibroblast, epithelial and endothelial cells conditioned media induce monocyte-derived dendritic cell maturation |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |