PL371130A1 - Sól acetylowa L-karnityny z organicznymi kwasami dikarboksylowymi oraz metody jej otrzymywania - Google Patents

Sól acetylowa L-karnityny z organicznymi kwasami dikarboksylowymi oraz metody jej otrzymywania

Info

Publication number
PL371130A1
PL371130A1 PL02371130A PL37113002A PL371130A1 PL 371130 A1 PL371130 A1 PL 371130A1 PL 02371130 A PL02371130 A PL 02371130A PL 37113002 A PL37113002 A PL 37113002A PL 371130 A1 PL371130 A1 PL 371130A1
Authority
PL
Poland
Prior art keywords
acetyl
dicarboxilic
preparing same
organic acid
carnitine salt
Prior art date
Application number
PL02371130A
Other languages
English (en)
Other versions
PL207877B1 (pl
Inventor
Aldo Fassi
Original Assignee
Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. filed Critical Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.
Publication of PL371130A1 publication Critical patent/PL371130A1/pl
Publication of PL207877B1 publication Critical patent/PL207877B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/08—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to hydrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/02—Preparation of carboxylic acid esters by interreacting ester groups, i.e. transesterification
PL371130A 2001-12-12 2002-11-25 Sól acetylo L-karnityny z organicznymi kwasami dikarboksylowymi oraz metody jej otrzymywania PL207877B1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2001RM000729A ITRM20010729A1 (it) 2001-12-12 2001-12-12 Sale di acetil l-carnitina con un acido organico dicarbossilico e procedimento per la sua preparazione.

Publications (2)

Publication Number Publication Date
PL371130A1 true PL371130A1 (pl) 2005-06-13
PL207877B1 PL207877B1 (pl) 2011-02-28

Family

ID=11455916

Family Applications (1)

Application Number Title Priority Date Filing Date
PL371130A PL207877B1 (pl) 2001-12-12 2002-11-25 Sól acetylo L-karnityny z organicznymi kwasami dikarboksylowymi oraz metody jej otrzymywania

Country Status (19)

Country Link
US (1) US6673837B2 (pl)
EP (1) EP1453791B1 (pl)
JP (1) JP4902940B2 (pl)
KR (1) KR100860386B1 (pl)
CN (1) CN1250521C (pl)
AT (1) ATE457300T1 (pl)
AU (1) AU2002358989A1 (pl)
CA (1) CA2468234C (pl)
CY (1) CY1110684T1 (pl)
DE (1) DE60235318D1 (pl)
DK (1) DK1453791T3 (pl)
ES (1) ES2339432T3 (pl)
HK (1) HK1073295A1 (pl)
HU (1) HU230034B1 (pl)
IT (1) ITRM20010729A1 (pl)
PL (1) PL207877B1 (pl)
PT (1) PT1453791E (pl)
SI (1) SI1453791T1 (pl)
WO (1) WO2003053911A1 (pl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8173618B2 (en) * 2003-07-25 2012-05-08 University Of Massachusetts Formulations for reducing neuronal degeneration
CN101209975B (zh) * 2006-12-29 2010-12-01 沈阳科硕营养科技有限公司 左旋肉碱富马酸钙及其制备方法与用途
US8597640B2 (en) * 2007-10-31 2013-12-03 University Of Massachusetts Lowell Over-the-counter vitamin/nutriceutical formulation that provides neuroprotection and maintains or improves cognitive performance in alzheimer's disease and normal aging
JP2012092036A (ja) * 2010-10-26 2012-05-17 Mitsubishi Rayon Co Ltd カルニチンの塩の製造方法
CA2846632A1 (en) * 2011-08-31 2013-03-07 The Procter & Gamble Company Fastening member having bonded reinforcing layer
JP5933383B2 (ja) * 2012-07-26 2016-06-08 ロート製薬株式会社 内服用固形製剤の吸湿性・流動性の改善方法、吸湿性・流動性が改善されてなる内服用固形製剤、及び該内服用固形製剤の製造法
JP6100939B2 (ja) * 2016-02-26 2017-03-22 ロート製薬株式会社 内服用固形製剤の吸湿性・流動性の改善方法、吸湿性・流動性が改善されてなる内服用固形製剤、及び該内服用固形製剤の製造法
JP6964876B2 (ja) * 2017-11-27 2021-11-10 株式会社古川リサーチオフィス オロット酸−カルニチン混合体粉体又はフマル酸−カルニチン混合体粉体の製造方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3463261D1 (en) * 1983-12-28 1987-05-27 Sigma Tau Ind Farmaceuti Salts of l-carnitine and alkanoyl l-carnitines and process for preparing same

Also Published As

Publication number Publication date
CN1250521C (zh) 2006-04-12
JP2005513122A (ja) 2005-05-12
JP4902940B2 (ja) 2012-03-21
CA2468234C (en) 2010-02-23
DK1453791T3 (da) 2010-05-25
AU2002358989A1 (en) 2003-07-09
HU230034B1 (hu) 2015-05-28
DE60235318D1 (de) 2010-03-25
PT1453791E (pt) 2010-04-14
EP1453791B1 (en) 2010-02-10
HK1073295A1 (en) 2005-09-30
HUP0402545A3 (en) 2012-09-28
KR20040064721A (ko) 2004-07-19
ATE457300T1 (de) 2010-02-15
CN1602294A (zh) 2005-03-30
CY1110684T1 (el) 2015-06-10
HUP0402545A2 (hu) 2005-04-28
PL207877B1 (pl) 2011-02-28
ES2339432T3 (es) 2010-05-20
WO2003053911A1 (en) 2003-07-03
ITRM20010729A1 (it) 2003-06-12
US6673837B2 (en) 2004-01-06
US20030119904A1 (en) 2003-06-26
CA2468234A1 (en) 2003-07-03
EP1453791A1 (en) 2004-09-08
KR100860386B1 (ko) 2008-09-26
SI1453791T1 (sl) 2010-11-30

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