PL368994A1 - Tieno-(1,3)-oksazyn-4-ony o działaniu hamującym lipazę - Google Patents
Tieno-(1,3)-oksazyn-4-ony o działaniu hamującym lipazęInfo
- Publication number
- PL368994A1 PL368994A1 PL02368994A PL36899402A PL368994A1 PL 368994 A1 PL368994 A1 PL 368994A1 PL 02368994 A PL02368994 A PL 02368994A PL 36899402 A PL36899402 A PL 36899402A PL 368994 A1 PL368994 A1 PL 368994A1
- Authority
- PL
- Poland
- Prior art keywords
- oxazin
- thieno
- ones
- inhibiting activity
- lipase inhibiting
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/14—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Cosmetics (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
- Detergent Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0121019A GB0121019D0 (en) | 2001-08-30 | 2001-08-30 | /nhibitors |
GB0206031A GB0206031D0 (en) | 2002-03-14 | 2002-03-14 | Inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
PL368994A1 true PL368994A1 (pl) | 2005-04-04 |
Family
ID=26246489
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL02368994A PL368994A1 (pl) | 2001-08-30 | 2002-08-23 | Tieno-(1,3)-oksazyn-4-ony o działaniu hamującym lipazę |
Country Status (20)
Country | Link |
---|---|
US (2) | US7407954B2 (pl) |
EP (1) | EP1446125B1 (pl) |
JP (2) | JP2005527469A (pl) |
KR (1) | KR100934256B1 (pl) |
CN (1) | CN1556706B (pl) |
AR (1) | AR036399A1 (pl) |
AT (1) | ATE429918T1 (pl) |
AU (1) | AU2002321536B2 (pl) |
CA (1) | CA2458213A1 (pl) |
DE (1) | DE60232170D1 (pl) |
HK (1) | HK1064940A1 (pl) |
HU (1) | HUP0401298A3 (pl) |
MX (1) | MXPA04001922A (pl) |
MY (1) | MY139608A (pl) |
NO (1) | NO20041295L (pl) |
NZ (1) | NZ531272A (pl) |
PL (1) | PL368994A1 (pl) |
RU (1) | RU2324696C2 (pl) |
WO (1) | WO2003020282A1 (pl) |
ZA (1) | ZA200401595B (pl) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100934256B1 (ko) * | 2001-08-30 | 2009-12-28 | 알리자임 테라퓨틱스 리미티드 | 리파제 억제 활성을 갖는 티에노(1,3)옥사진-4-온 |
CN1620439A (zh) * | 2001-12-20 | 2005-05-25 | Osi药物公司 | 胰脂肪酶抑制剂化合物、其合成方法和应用 |
JP2008517061A (ja) * | 2004-10-20 | 2008-05-22 | コンパス ファーマシューティカルズ リミティド ライアビリティ カンパニー | 抗腫瘍剤としての化合物及びそれらの使用 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1247547A (en) * | 1983-06-22 | 1988-12-28 | Paul Hadvary | Leucine derivatives |
DE3540377A1 (de) * | 1985-11-14 | 1987-05-21 | Bayer Ag | Thienooxazinone, verfahren zu ihrer herstellung und ihre verwendung als leistungsfoerderer |
IL125947A0 (en) | 1997-09-17 | 1999-04-11 | American Cyanamid Co | 3-(1,2-benzisothiazol- and isoxazol-5-yl)-2,4(1h,3h)-pyrimidinedione or thione and 3-(1,2-benzisothiazol- and isoxazol-5-yl)-4(3)-pyrimidinone or thione herbicidal agents |
EP0985670A1 (en) | 1998-08-13 | 2000-03-15 | American Cyanamid Company | 1-(3-Heterocyclylphenyl)isothiourea, -isourea, -guanidine and -amidine compounds as herbicides |
AU1375000A (en) | 1998-11-26 | 2000-06-13 | Novo Nordisk A/S | Heterocyclic compounds regulating clotting |
GB9900416D0 (en) * | 1999-01-08 | 1999-02-24 | Alizyme Therapeutics Ltd | Inhibitors |
AR022204A1 (es) | 1999-01-08 | 2002-09-04 | Norgine Bv | Compuesto, proceso para su preparacion, composicion farmaceutica y producto comestible que lo comprende. |
JP2003509538A (ja) * | 1999-09-10 | 2003-03-11 | ザ、プロクター、エンド、ギャンブル、カンパニー | 酵素インヒビター |
GB0001572D0 (en) * | 2000-01-24 | 2000-03-15 | Alizyme Therapeutics Ltd | Inhibitors |
JP2002105081A (ja) * | 2000-07-28 | 2002-04-10 | Nikken Chem Co Ltd | 新規チオフェンニ環化合物 |
KR100934256B1 (ko) * | 2001-08-30 | 2009-12-28 | 알리자임 테라퓨틱스 리미티드 | 리파제 억제 활성을 갖는 티에노(1,3)옥사진-4-온 |
CN1620439A (zh) * | 2001-12-20 | 2005-05-25 | Osi药物公司 | 胰脂肪酶抑制剂化合物、其合成方法和应用 |
-
2002
- 2002-08-23 KR KR1020047002805A patent/KR100934256B1/ko not_active IP Right Cessation
- 2002-08-23 EP EP02755241A patent/EP1446125B1/en not_active Expired - Lifetime
- 2002-08-23 MX MXPA04001922A patent/MXPA04001922A/es active IP Right Grant
- 2002-08-23 RU RU2004109588/04A patent/RU2324696C2/ru not_active IP Right Cessation
- 2002-08-23 JP JP2003524589A patent/JP2005527469A/ja not_active Withdrawn
- 2002-08-23 AT AT02755241T patent/ATE429918T1/de not_active IP Right Cessation
- 2002-08-23 CN CN028185900A patent/CN1556706B/zh not_active Expired - Fee Related
- 2002-08-23 HU HU0401298A patent/HUP0401298A3/hu unknown
- 2002-08-23 CA CA002458213A patent/CA2458213A1/en not_active Abandoned
- 2002-08-23 PL PL02368994A patent/PL368994A1/pl not_active Application Discontinuation
- 2002-08-23 WO PCT/GB2002/003903 patent/WO2003020282A1/en active IP Right Grant
- 2002-08-23 NZ NZ531272A patent/NZ531272A/en not_active IP Right Cessation
- 2002-08-23 US US10/488,045 patent/US7407954B2/en not_active Expired - Fee Related
- 2002-08-23 AU AU2002321536A patent/AU2002321536B2/en not_active Ceased
- 2002-08-23 DE DE60232170T patent/DE60232170D1/de not_active Expired - Lifetime
- 2002-08-29 MY MYPI20023211A patent/MY139608A/en unknown
- 2002-08-30 AR ARP020103295A patent/AR036399A1/es unknown
-
2004
- 2004-02-25 ZA ZA2004/01595A patent/ZA200401595B/en unknown
- 2004-03-29 NO NO20041295A patent/NO20041295L/no not_active Application Discontinuation
- 2004-10-07 HK HK04107740.4A patent/HK1064940A1/xx not_active IP Right Cessation
-
2008
- 2008-07-24 US US12/178,920 patent/US20090029978A1/en not_active Abandoned
-
2010
- 2010-01-29 JP JP2010019160A patent/JP2010159260A/ja not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
JP2005527469A (ja) | 2005-09-15 |
US20090029978A1 (en) | 2009-01-29 |
KR20040052216A (ko) | 2004-06-22 |
NO20041295L (no) | 2004-03-29 |
KR100934256B1 (ko) | 2009-12-28 |
US7407954B2 (en) | 2008-08-05 |
EP1446125B1 (en) | 2009-04-29 |
US20050075336A1 (en) | 2005-04-07 |
HUP0401298A2 (hu) | 2004-10-28 |
ATE429918T1 (de) | 2009-05-15 |
MXPA04001922A (es) | 2005-03-07 |
MY139608A (en) | 2009-10-30 |
EP1446125A1 (en) | 2004-08-18 |
HK1064940A1 (en) | 2005-02-08 |
DE60232170D1 (de) | 2009-06-10 |
AU2002321536B2 (en) | 2007-05-17 |
HUP0401298A3 (en) | 2008-03-28 |
ZA200401595B (en) | 2005-05-25 |
CN1556706A (zh) | 2004-12-22 |
AR036399A1 (es) | 2004-09-08 |
RU2324696C2 (ru) | 2008-05-20 |
CN1556706B (zh) | 2011-04-27 |
JP2010159260A (ja) | 2010-07-22 |
WO2003020282A1 (en) | 2003-03-13 |
CA2458213A1 (en) | 2003-03-13 |
NZ531272A (en) | 2006-01-27 |
RU2004109588A (ru) | 2005-05-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HK1061852A1 (en) | 4,5-dihydro-ih-pyrazole derivatives having cb1-antagonistic activity | |
MXPA01013362A (es) | Anticuerpos de humano, anti-alfavbeta3 recombinantes, °cidos nucleicos que codifican a los mismos y metodos de uso. | |
IL160081A0 (en) | Novel 4,5-dihydro-1h-pyrazole derivatives having cb1-antagonistic activity | |
ZA200200477B (en) | 2-pyrazolin-5-ones. | |
AU2002357860A8 (en) | Enzymes | |
HK1054384A1 (en) | 4-Pyrimidinyl-n-acyl-l-phenylalanines. | |
HUP0402171A3 (en) | Pyrazolopyrimidinone derivatives having pde7-inhibitory activity | |
ZA200202537B (en) | Pour-on-formulations. | |
ZA200201829B (en) | New phenylpiperazines. | |
ZA200203762B (en) | 4-pyridinyl-IN-acyl-L-phenylalanines. | |
IL154364A0 (en) | Arylalkane-sulfonamides having endothelin-antagonist activity | |
HK1048318A1 (en) | Substituted 3-phenyl-5-alkoxi-1,3,4-oxdiazol-2-ones and their use as lipase inhibitors. | |
IL162310A0 (en) | 3,4-Dihydro-1h-isoquinoloin-2-yl-derivatives | |
MXPA02000261A (es) | Aminoindanos novedosos. | |
HK1064940A1 (en) | Thieno-(1,3)-oxazin-4-ones with lipase inhibiting activity | |
GB0029720D0 (en) | I.S machine7544232001 | |
PL375417A1 (pl) | 2,3-Dihydroizoindol-1-ony o działaniu hamującym MAO-B | |
AP2003002872A0 (en) | Plant invigorator. | |
ZA200204581B (en) | Nitro-sulfobenzamides. | |
HK1031254A1 (en) | Tachogragh. | |
ZA200002987B (en) | Novel processes and intermediates. | |
GB0102946D0 (en) | Enzyme | |
GB0121840D0 (en) | Modified enzyme | |
TW452027U (en) | Improved bearing | |
GB0124575D0 (en) | Enzyme |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
REFS | Decisions on refusal to grant patents (taken after the publication of the particulars of the applications) |