PL366134A1 - Sposób wytwarzania aktywnego fizjologicznie polipeptydu IL-18 - Google Patents

Sposób wytwarzania aktywnego fizjologicznie polipeptydu IL-18

Info

Publication number
PL366134A1
PL366134A1 PL01366134A PL36613401A PL366134A1 PL 366134 A1 PL366134 A1 PL 366134A1 PL 01366134 A PL01366134 A PL 01366134A PL 36613401 A PL36613401 A PL 36613401A PL 366134 A1 PL366134 A1 PL 366134A1
Authority
PL
Poland
Prior art keywords
polypeptide
preparing
physiologically active
physiologically
active
Prior art date
Application number
PL01366134A
Other languages
English (en)
Inventor
Kyung O. Johanson
Robert B. Kirkpatrick
Allan R. Shatzman
Yen Sen Ho
Patrick Mcdevitt
Original Assignee
Smithkline Beecham Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corporation filed Critical Smithkline Beecham Corporation
Publication of PL366134A1 publication Critical patent/PL366134A1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL01366134A 2000-06-15 2001-06-11 Sposób wytwarzania aktywnego fizjologicznie polipeptydu IL-18 PL366134A1 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US21183200P 2000-06-15 2000-06-15
US22412800P 2000-08-10 2000-08-10
US26492301P 2001-01-20 2001-01-20

Publications (1)

Publication Number Publication Date
PL366134A1 true PL366134A1 (pl) 2005-01-24

Family

ID=27395664

Family Applications (2)

Application Number Title Priority Date Filing Date
PL387774A PL208592B1 (pl) 2000-06-15 2001-06-11 Sposób wytwarzania aktywnego ludzkiego polipeptydu IL-18 z ludzkiego polipeptydu prekursora IL-18
PL01366134A PL366134A1 (pl) 2000-06-15 2001-06-11 Sposób wytwarzania aktywnego fizjologicznie polipeptydu IL-18

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL387774A PL208592B1 (pl) 2000-06-15 2001-06-11 Sposób wytwarzania aktywnego ludzkiego polipeptydu IL-18 z ludzkiego polipeptydu prekursora IL-18

Country Status (24)

Country Link
US (2) US7186528B2 (pl)
EP (1) EP1292697B1 (pl)
JP (1) JP5121109B2 (pl)
KR (1) KR20030022144A (pl)
CN (1) CN100390281C (pl)
AR (1) AR033979A1 (pl)
AT (1) ATE437234T1 (pl)
AU (2) AU2001280442B2 (pl)
BR (1) BR0111692A (pl)
CA (1) CA2412730C (pl)
CZ (1) CZ20024085A3 (pl)
DE (1) DE60139316D1 (pl)
DK (1) DK1292697T3 (pl)
ES (1) ES2329875T3 (pl)
HU (1) HUP0501002A3 (pl)
IL (2) IL153422A0 (pl)
MX (1) MXPA02012292A (pl)
MY (1) MY136526A (pl)
NO (1) NO330682B1 (pl)
NZ (1) NZ522845A (pl)
PL (2) PL208592B1 (pl)
PT (1) PT1292697E (pl)
SI (1) SI1292697T1 (pl)
WO (1) WO2001098455A2 (pl)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK12942002A3 (sk) * 2000-02-10 2003-05-02 Abbott Laboratories Protilátky viažuce ľudský interleukín-18, spôsoby ich výroby a použitia
EP1613274B1 (en) 2003-04-15 2010-03-03 GlaxoSmithKline LLC Human il-18 substitution mutants and their conjugates
ATE495189T1 (de) 2003-08-15 2011-01-15 Univ Florida Die identifikation von polynukleotiden von porphyromonas gingivalis-virulenz zur diagnose, behandlung und beobachtung von periodontalerkrankungen
US7968684B2 (en) * 2003-11-12 2011-06-28 Abbott Laboratories IL-18 binding proteins
CA2545024A1 (en) * 2003-11-24 2005-06-02 Novo Nordisk A/S Fusion proteins and methods of cleavage of such proteins
ATE526057T1 (de) * 2004-08-20 2011-10-15 Glaxosmithkline Llc Wundheilung durch verabreichung von menschlichem il-18
US20100061958A1 (en) 2006-09-14 2010-03-11 The Trustees Of The University Of Pennsylvania Modulation of Regulatory T Cells by Human IL-18
AR065803A1 (es) * 2007-03-23 2009-07-01 Smithkline Beecham Corp Uso de un polipeptido de il- 18 humana y un anticuerpo anti- cd para preparar unmedicamento
US11219672B2 (en) 2014-08-07 2022-01-11 Haruki Okamura Therapeutic agent for cancer which comprises combination of IL-18 and molecule-targeting antibody
JP2019023165A (ja) * 2015-12-11 2019-02-14 国立大学法人京都大学 インターロイキン−１８活性阻害剤
JP7795181B2 (ja) 2017-09-06 2026-01-07 イェール ユニバーシティー インターロイキン－１８バリアントとその利用法
KR20200080749A (ko) * 2018-12-27 2020-07-07 주식회사 폴루스 N-말단의 메티오닌이 절단된 목적 단백질 발현용 유전자 발현 카세트 및 이를 이용하여 n-말단의 메티오닌이 절단된 목적 단백질을 생산하는 방법
AU2023226512A1 (en) 2022-02-23 2024-08-29 Bright Peak Therapeutics Ag Immune antigen specific il-18 immunocytokines and uses thereof

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6204261B1 (en) * 1995-12-20 2001-03-20 Vertex Pharmaceuticals Incorporated Inhibitors of interleukin-1β Converting enzyme inhibitors
US5985863A (en) * 1996-09-12 1999-11-16 Vertex Pharmaceuticals, Inc. Compositions and methods for decreasing IGIF and IFN-γ production by administering an ICE inhibitor
US5192324A (en) 1982-02-18 1993-03-09 Howmedica Inc. Bone prosthesis with porous coating
EP0324789B1 (en) * 1986-10-02 2003-08-20 Massachusetts Institute Of Technology Methods of regulating metabolic stability of proteins
US5212058A (en) 1990-05-09 1993-05-18 Massachusetts Institute Of Technology Nucleic acid encoding ubiquitin-specific proteases
ES2071315T3 (es) 1990-05-09 1995-06-16 Massachusetts Inst Technology Proteasa especifica de ubiquitina.
US5914254A (en) * 1993-08-02 1999-06-22 Celtrix Pharmaceuticals, Inc. Expression of fusion polypeptides transported out of the cytoplasm without leader sequences
US6110701A (en) 1994-04-08 2000-08-29 Merck Frosst Canada & Co. DNA encoding precursor of interleukin-1β converting enzyme--related cysteine proteinase II (ICErel -II)
US5552536A (en) 1994-04-08 1996-09-03 Merck Frosst Canada, Inc. DNA encoding precursor of interleukin-1 beta converting enzyme - related cysteine proteinase III (ice rel-III)
DE69519454T2 (de) 1994-07-14 2001-05-03 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo, Okayama Protein, das Interferon-Gamma Herstellung induziert und monoklonaler Antikörper dagegen
JP2724987B2 (ja) 1994-11-15 1998-03-09 株式会社林原生物化学研究所 インターフェロン−γの産生を誘導するポリペプチド
TW581771B (en) 1994-11-15 2004-04-01 Hayashibara Biochem Lab Recombinant production of a polypeptide for inducing interferon-gamma production, and monoclonal antibody against the polypeptide
US6074050A (en) 1997-12-03 2000-06-13 Hewlett-Packard Company Method and apparatus for venting an ink container
CA2238885A1 (en) 1995-12-29 1997-07-10 Incyte Pharmaceuticals, Inc. Nucleic acids encoding interferon gamma inducing factor-2
JPH1080270A (ja) * 1996-07-19 1998-03-31 Hayashibara Biochem Lab Inc ポリペプチドをプロセッシングする酵素
TW515843B (en) * 1996-07-25 2003-01-01 Hayashibara Biochem Lab Process for producing an active polypeptide inducing interferon-γ production
JP4010606B2 (ja) * 1996-07-25 2007-11-21 株式会社林原生物化学研究所 ポリペプチドの製造方法
US6054487A (en) * 1997-03-18 2000-04-25 Basf Aktiengesellschaft Methods and compositions for modulating responsiveness to corticosteroids
WO1999037793A1 (en) * 1998-01-23 1999-07-29 Novo Nordisk A/S Process for making desired polypeptides in yeast

Also Published As

Publication number Publication date
CZ20024085A3 (cs) 2003-05-14
AU2001280442B2 (en) 2005-10-27
MY136526A (en) 2008-10-31
US7186528B2 (en) 2007-03-06
HUP0501002A3 (en) 2010-01-28
WO2001098455A2 (en) 2001-12-27
NZ522845A (en) 2005-07-29
US7442526B2 (en) 2008-10-28
DE60139316D1 (de) 2009-09-03
EP1292697A2 (en) 2003-03-19
CN1436246A (zh) 2003-08-13
NO20026002L (no) 2003-02-12
KR20030022144A (ko) 2003-03-15
JP2004523204A (ja) 2004-08-05
MXPA02012292A (es) 2003-04-25
HUP0501002A2 (en) 2006-01-30
BR0111692A (pt) 2005-08-30
IL153422A (en) 2011-03-31
ATE437234T1 (de) 2009-08-15
CN100390281C (zh) 2008-05-28
JP5121109B2 (ja) 2013-01-16
US20030143198A1 (en) 2003-07-31
CA2412730A1 (en) 2001-12-27
PT1292697E (pt) 2009-10-28
WO2001098455A3 (en) 2002-08-08
SI1292697T1 (sl) 2009-12-31
HK1055138A1 (en) 2003-12-24
CA2412730C (en) 2011-08-16
US20060177422A1 (en) 2006-08-10
AU8044201A (en) 2002-01-02
DK1292697T3 (da) 2009-11-16
EP1292697B1 (en) 2009-07-22
NO20026002D0 (no) 2002-12-13
ES2329875T3 (es) 2009-12-02
AR033979A1 (es) 2004-01-21
IL153422A0 (en) 2003-07-06
NO330682B1 (no) 2011-06-06
EP1292697A4 (en) 2005-08-10
PL208592B1 (pl) 2011-05-31

Similar Documents

Publication Publication Date Title
IL153282A0 (en) Method for preparing a pharmaceutical composition
AU2398101A (en) Method for manufacturing seamless capsule
HUP0301268A3 (en) Method for producing powdery formulations
AU9564401A (en) Method for preparing a trademark registration request
IL153422A0 (en) Method for preparing a physiologically active il-18 polypeptide
IL144454A0 (en) Method for producing l-phenylephrine hydrochloride
AU7901300A (en) Method for producing a channel-forming protein
GB0119019D0 (en) Structure for connecting battery termin al
IL144176A0 (en) Method for preparing a benzylic-type ether
PL371763A1 (pl) Sposób wytwarzania pochodnych echinokandyny
AU5031801A (en) Memno peptides, a process for their preparation and their use
AU2002210585A1 (en) Method for modifying a protein structure
PL349857A1 (en) Method for producing film-type dosage forms
AU4663601A (en) Method for preparing 9-deoxo-8a-aza-(8a-alkyl)-8a-homoerythromycin derivativesfrom 9-deoxo-9(z)-hydroxyiminoerythromycin
GB2372406B (en) Preparing for handover in a communication system
SG99292A1 (en) A method for producing oxide compounds
SI1229860T1 (en) Method for manufacturing a medical implant
TW417472U (en) Cut-off structure for tissue machine
GB2352625B (en) A high chair
TW507560U (en) Bedstand for sickbed
TJ20000636A (en) A method of obtaining of a biologically active preparation chormagz
TW483380U (en) Structure improvement for stem
AU7618601A (en) A method of preparing a pharmaceutical composition
AU146252S (en) A couch
TW433047U (en) Structure improvement for stethoscope

Legal Events

Date Code Title Description
REFS Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)