PL359409A1 - Związki przydatne do wytwarzania leków o działaniu inhibitującym fosfodiesterazę IV - Google Patents
Związki przydatne do wytwarzania leków o działaniu inhibitującym fosfodiesterazę IVInfo
- Publication number
- PL359409A1 PL359409A1 PL01359409A PL35940901A PL359409A1 PL 359409 A1 PL359409 A1 PL 359409A1 PL 01359409 A PL01359409 A PL 01359409A PL 35940901 A PL35940901 A PL 35940901A PL 359409 A1 PL359409 A1 PL 359409A1
- Authority
- PL
- Poland
- Prior art keywords
- medicaments
- preparation
- phosphodiesterase
- inhibitory activity
- compounds useful
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C229/36—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/47—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/734—Ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/09—Geometrical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT2000RM000341A IT1317049B1 (it) | 2000-06-23 | 2000-06-23 | Composti utili per la preparazione di medicamenti ad attivita'inibitrice della fosfodiesterasi iv. |
PCT/IT2001/000312 WO2002000593A2 (en) | 2000-06-23 | 2001-06-15 | Compounds useful for the preparation of medicaments with phosphodiesterase iv inhibitory activity |
Publications (1)
Publication Number | Publication Date |
---|---|
PL359409A1 true PL359409A1 (pl) | 2004-08-23 |
Family
ID=11454800
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL01359409A PL359409A1 (pl) | 2000-06-23 | 2001-06-15 | Związki przydatne do wytwarzania leków o działaniu inhibitującym fosfodiesterazę IV |
Country Status (13)
Country | Link |
---|---|
US (1) | US7169808B2 (pl) |
EP (1) | EP1292563A2 (pl) |
JP (1) | JP2004501888A (pl) |
KR (1) | KR100764885B1 (pl) |
AU (1) | AU2001269420A1 (pl) |
CA (1) | CA2411162A1 (pl) |
CZ (1) | CZ20023948A3 (pl) |
HU (2) | HUP0301205A3 (pl) |
IT (1) | IT1317049B1 (pl) |
MX (1) | MXPA02012589A (pl) |
PL (1) | PL359409A1 (pl) |
SK (1) | SK17302002A3 (pl) |
WO (1) | WO2002000593A2 (pl) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8026280B2 (en) * | 2001-03-27 | 2011-09-27 | Errant Gene Therapeutics, Llc | Histone deacetylase inhibitors |
US7842727B2 (en) | 2001-03-27 | 2010-11-30 | Errant Gene Therapeutics, Llc | Histone deacetylase inhibitors |
US7312247B2 (en) * | 2001-03-27 | 2007-12-25 | Errant Gene Therapeutics, Llc | Histone deacetylase inhibitors |
WO2003099272A1 (en) | 2002-05-22 | 2003-12-04 | Errant Gene Therapeutics, Llc | Histone deacetylase inhibitors based on alpha-ketoepoxide compounds |
JP2006508986A (ja) | 2002-11-20 | 2006-03-16 | エルラント ゲネ セラペウチクス エルエルシー | ヒストンデアセチラーゼ阻害剤による肺細胞の治療方法 |
US20080132539A1 (en) * | 2003-12-25 | 2008-06-05 | Junji Kakuchi | Hydroxamic Acid Derivative And Age Generation Inhibitor Containing The Derivative |
GB0818907D0 (en) * | 2008-10-15 | 2008-11-19 | Isis Innovation | Histone lysine demethylase inhibitors |
KR20200061381A (ko) | 2017-10-05 | 2020-06-02 | 바이오젠 인크. | 알파-카르복스아미드 피롤리딘 유도체를 제조하기 위한 공정 |
JP2022526431A (ja) * | 2019-04-10 | 2022-05-24 | バイオジェン インコーポレイテッド | アルファ-カルボキサミドピロリジン誘導体を調製するためのプロセス |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3714356A (en) * | 1971-01-18 | 1973-01-30 | Morton Norwich Products Inc | Antibacterial composition and method |
GB1419968A (en) | 1972-12-21 | 1975-12-31 | Wyeth John & Brother Ltd | Aziridine derivatives |
AU6889274A (en) * | 1973-05-17 | 1975-11-20 | Astra Laekemedel Ab | Treatment of neurological disorders |
DE3160641D1 (en) * | 1980-05-13 | 1983-08-25 | Ciba Geigy Ag | Process for the preparation of benzene or naphthalene alkenyl carboxylic acid derivatives |
US4820828A (en) * | 1987-03-04 | 1989-04-11 | Ortho Pharmaceutical Corporation | Cinnamohydroxamic acids |
US4971959A (en) * | 1987-04-14 | 1990-11-20 | Warner-Lambert Company | Trisubstituted phenyl analogs having activity for congestive heart failure |
US5232735A (en) * | 1990-06-01 | 1993-08-03 | Bioresearch, Inc. | Ingestibles containing substantially tasteless sweetness inhibitors as bitter taste reducers or substantially tasteless bitter inhibitors as sweet taste reducers |
ZW9091A1 (en) | 1990-07-10 | 1992-04-29 | Smithkline Beecham Corp | Oxamides |
US5191084A (en) * | 1991-05-01 | 1993-03-02 | American Home Products Corporation | Phenyl pyrazolidinones as bronchodilators and anti-inflammatory agents |
PT100441A (pt) | 1991-05-02 | 1993-09-30 | Smithkline Beecham Corp | Pirrolidinonas, seu processo de preparacao, composicoes farmaceuticas que as contem e uso |
US5665754A (en) * | 1993-09-20 | 1997-09-09 | Glaxo Wellcome Inc. | Substituted pyrrolidines |
DE69616357T2 (de) * | 1995-07-26 | 2002-07-11 | Takeda Chemical Industries Ltd | Benzocycloalken-verbindungen mit bindungsaffinität an den melatonin-rezeptor, ihre herstellung und verwendung |
ATE197038T1 (de) * | 1995-07-26 | 2000-11-15 | Pfizer | N-aroyl-glycin-hydroxamsäure-derivate und verwandte verbindungen |
JP4017214B2 (ja) * | 1996-06-11 | 2007-12-05 | 興和創薬株式会社 | 5−フェニル−3−ピリダジノン誘導体 |
ATE236872T1 (de) * | 1996-08-12 | 2003-04-15 | Celgene Corp | Immunotherapeutische mittel und ihre anwendung in der reduzierung der cytokininwerte |
GB9618349D0 (en) * | 1996-09-03 | 1996-10-16 | Pharmacia Spa | N-substituted 2-amino-4-phenyl-4-oxo-butanoic acid derivatives with kynurenine-3-hydroxylase inhibitory activity |
TW530058B (en) * | 1997-07-22 | 2003-05-01 | Astra Pharma Prod | Triazolo [4,5-d]pyrimidine compounos and their use and process for preparation |
IT1294931B1 (it) * | 1997-09-22 | 1999-04-23 | Sigma Tau Ind Farmaceuti | Derivati della 2-amminotetralina procedimento per la loro preparazione e composizioni farmaceutiche che li contengono, attive nella |
CA2315370A1 (en) | 1997-12-17 | 1999-06-24 | Merck & Co., Inc. | Integrin receptor antagonists |
US6028116A (en) * | 1998-04-03 | 2000-02-22 | Cell Pathways, Inc. | Substituted condensation products of 1H-indenyl-hydroxyalkanes with aldehydes for neoplasia |
ATE321042T1 (de) * | 1998-12-14 | 2006-04-15 | Astellas Pharma Inc | Piperazin-derivate |
DE19952146A1 (de) | 1999-10-29 | 2001-06-07 | Boehringer Ingelheim Pharma | Arylalkane, Arylalkene und Aryl-azaalkane, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
-
2000
- 2000-06-23 IT IT2000RM000341A patent/IT1317049B1/it active
-
2001
- 2001-06-15 PL PL01359409A patent/PL359409A1/pl not_active Application Discontinuation
- 2001-06-15 EP EP01947782A patent/EP1292563A2/en not_active Withdrawn
- 2001-06-15 AU AU2001269420A patent/AU2001269420A1/en not_active Abandoned
- 2001-06-15 JP JP2002505343A patent/JP2004501888A/ja active Pending
- 2001-06-15 US US10/311,756 patent/US7169808B2/en not_active Expired - Fee Related
- 2001-06-15 HU HU0301205A patent/HUP0301205A3/hu unknown
- 2001-06-15 WO PCT/IT2001/000312 patent/WO2002000593A2/en active Application Filing
- 2001-06-15 CZ CZ20023948A patent/CZ20023948A3/cs unknown
- 2001-06-15 MX MXPA02012589A patent/MXPA02012589A/es active IP Right Grant
- 2001-06-15 HU HU0303399A patent/HUP0303399A3/hu unknown
- 2001-06-15 KR KR1020027016531A patent/KR100764885B1/ko not_active IP Right Cessation
- 2001-06-15 CA CA002411162A patent/CA2411162A1/en not_active Abandoned
- 2001-06-15 SK SK1730-2002A patent/SK17302002A3/sk unknown
Also Published As
Publication number | Publication date |
---|---|
CZ20023948A3 (cs) | 2003-04-16 |
HUP0301205A2 (hu) | 2003-11-28 |
US20030195257A1 (en) | 2003-10-16 |
ITRM20000341A0 (it) | 2000-06-23 |
IT1317049B1 (it) | 2003-05-26 |
US7169808B2 (en) | 2007-01-30 |
KR100764885B1 (ko) | 2007-10-09 |
WO2002000593A3 (en) | 2002-05-16 |
KR20030012870A (ko) | 2003-02-12 |
SK17302002A3 (sk) | 2003-05-02 |
MXPA02012589A (es) | 2003-05-14 |
HUP0301205A3 (en) | 2004-03-01 |
HUP0303399A2 (hu) | 2004-01-28 |
EP1292563A2 (en) | 2003-03-19 |
WO2002000593A2 (en) | 2002-01-03 |
CA2411162A1 (en) | 2002-01-03 |
AU2001269420A1 (en) | 2002-01-08 |
JP2004501888A (ja) | 2004-01-22 |
HUP0303399A3 (en) | 2004-10-28 |
ITRM20000341A1 (it) | 2001-12-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
REFS | Decisions on refusal to grant patents (taken after the publication of the particulars of the applications) |