PL358333A1 - Nitroiloksylowe pochodne (R) i (S)-karnityny - Google Patents
Nitroiloksylowe pochodne (R) i (S)-karnitynyInfo
- Publication number
- PL358333A1 PL358333A1 PL00358333A PL35833300A PL358333A1 PL 358333 A1 PL358333 A1 PL 358333A1 PL 00358333 A PL00358333 A PL 00358333A PL 35833300 A PL35833300 A PL 35833300A PL 358333 A1 PL358333 A1 PL 358333A1
- Authority
- PL
- Poland
- Prior art keywords
- carnitine
- derivatives
- formula
- nitroxy derivatives
- nitroxy
- Prior art date
Links
- PHIQHXFUZVPYII-LURJTMIESA-N (S)-carnitine Chemical compound C[N+](C)(C)C[C@@H](O)CC([O-])=O PHIQHXFUZVPYII-LURJTMIESA-N 0.000 title abstract 2
- -1 Nitroxy derivatives of (r) Chemical class 0.000 title 1
- PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical class C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 206010002383 Angina Pectoris Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 208000031225 myocardial ischemia Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/16—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions not involving the amino or carboxyl groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/30—Preparation of optical isomers
- C07C227/32—Preparation of optical isomers by stereospecific synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITRM99A000508 | 1999-08-05 | ||
| IT1999RM000508A IT1306184B1 (it) | 1999-08-05 | 1999-08-05 | Nitrilossi derivati della (r) e (s)-carnitina. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL358333A1 true PL358333A1 (pl) | 2004-08-09 |
| PL203519B1 PL203519B1 (pl) | 2009-10-30 |
Family
ID=
Also Published As
| Publication number | Publication date |
|---|---|
| PT1224161E (pt) | 2005-01-31 |
| US20020119965A1 (en) | 2002-08-29 |
| KR100772205B1 (ko) | 2007-11-01 |
| HUP0203034A2 (hu) | 2003-02-28 |
| DE60013876D1 (de) | 2004-10-21 |
| HUP0203034A3 (en) | 2003-11-28 |
| CZ20025A3 (cs) | 2002-07-17 |
| ITRM990508A0 (it) | 1999-08-05 |
| ES2226896T3 (es) | 2005-04-01 |
| JP2003506429A (ja) | 2003-02-18 |
| SK287134B6 (sk) | 2010-01-07 |
| US6548693B2 (en) | 2003-04-15 |
| DE60013876T2 (de) | 2005-09-29 |
| EP1224161B1 (en) | 2004-09-15 |
| ATE276231T1 (de) | 2004-10-15 |
| CA2379047A1 (en) | 2001-02-15 |
| EP1224161A1 (en) | 2002-07-24 |
| ITRM990508A1 (it) | 2001-02-05 |
| IT1306184B1 (it) | 2001-05-30 |
| DK1224161T3 (da) | 2005-01-24 |
| US6395923B2 (en) | 2002-05-28 |
| KR20020025213A (ko) | 2002-04-03 |
| WO2001010819A1 (en) | 2001-02-15 |
| US20010011074A1 (en) | 2001-08-02 |
| AU6470400A (en) | 2001-03-05 |
| SK1752002A3 (en) | 2002-06-04 |
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