PL356096A1 - Kompleks N-formylopeptydowego receptora z czynnikiem modyfikacji ścieżki sygnału kinazy białkowej Goraz sposoby zmiany przekazywania sygnału poprzezstymulację czynnikami prozapalnymi - Google Patents

Kompleks N-formylopeptydowego receptora z czynnikiem modyfikacji ścieżki sygnału kinazy białkowej Goraz sposoby zmiany przekazywania sygnału poprzezstymulację czynnikami prozapalnymi

Info

Publication number
PL356096A1
PL356096A1 PL00356096A PL35609600A PL356096A1 PL 356096 A1 PL356096 A1 PL 356096A1 PL 00356096 A PL00356096 A PL 00356096A PL 35609600 A PL35609600 A PL 35609600A PL 356096 A1 PL356096 A1 PL 356096A1
Authority
PL
Poland
Prior art keywords
protein kinase
receptor complex
modification agent
signal pathway
peptide receptor
Prior art date
Application number
PL00356096A
Other languages
English (en)
Inventor
James A. Clagett
Craig Palmer
Original Assignee
Histatek, Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Histatek, Llc filed Critical Histatek, Llc
Publication of PL356096A1 publication Critical patent/PL356096A1/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1002Tetrapeptides with the first amino acid being neutral
    • C07K5/1005Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1013Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05Dipeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07Tetrapeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0802Tripeptides with the first amino acid being neutral
    • C07K5/0804Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/081Tripeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Transplantation (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
PL00356096A 1999-10-15 2000-10-12 Kompleks N-formylopeptydowego receptora z czynnikiem modyfikacji ścieżki sygnału kinazy białkowej Goraz sposoby zmiany przekazywania sygnału poprzezstymulację czynnikami prozapalnymi PL356096A1 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15967799P 1999-10-15 1999-10-15
PCT/US2000/028183 WO2001029069A1 (en) 1999-10-15 2000-10-12 N-formyl peptide receptor complex with a g-protein kinase signal pathway modification agent

Publications (1)

Publication Number Publication Date
PL356096A1 true PL356096A1 (pl) 2004-06-14

Family

ID=22573520

Family Applications (1)

Application Number Title Priority Date Filing Date
PL00356096A PL356096A1 (pl) 1999-10-15 2000-10-12 Kompleks N-formylopeptydowego receptora z czynnikiem modyfikacji ścieżki sygnału kinazy białkowej Goraz sposoby zmiany przekazywania sygnału poprzezstymulację czynnikami prozapalnymi

Country Status (16)

Country Link
EP (1) EP1222199A4 (pl)
JP (1) JP2004507441A (pl)
KR (1) KR20020057972A (pl)
CN (1) CN100497374C (pl)
AU (1) AU8014200A (pl)
BR (1) BR0014742A (pl)
CA (1) CA2387559A1 (pl)
CZ (1) CZ20021342A3 (pl)
EA (1) EA200200451A1 (pl)
HU (1) HUP0203688A2 (pl)
IL (1) IL149125A0 (pl)
MX (1) MXPA02003782A (pl)
NO (1) NO20021732L (pl)
PL (1) PL356096A1 (pl)
WO (1) WO2001029069A1 (pl)
ZA (1) ZA200202937B (pl)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6844315B2 (en) 1998-05-20 2005-01-18 Erasmus Universiteit Rotterdam Immunoregulator
EP1138692A1 (en) 2000-03-29 2001-10-04 Erasmus Universiteit Rotterdam Fragments of human chorionic gonadotropin (hcg) as immunoregulator
US20030220258A1 (en) 2001-12-21 2003-11-27 Robbert Benner Treatment of ischemic events
US8680059B2 (en) 1998-05-20 2014-03-25 Biotempt B.V. Oligopeptide acetate and formulations thereof
US7358330B2 (en) 2001-03-29 2008-04-15 Biotempt B.V. Immunoregulatory compositions
USRE43279E1 (en) 2000-03-29 2012-03-27 Biotemp B.V. Compositions capable of reducing elevated blood urea concentration
EP1300418A1 (en) * 2001-10-04 2003-04-09 Erasmus Universiteit Rotterdam Gene regulation by oligopeptides
US7786084B2 (en) 2001-12-21 2010-08-31 Biotempt B.V. Treatment of burns
US7560433B2 (en) 2001-12-21 2009-07-14 Biotempt B.V. Treatment of multiple sclerosis (MS)
WO2004100978A1 (en) * 2003-05-13 2004-11-25 Medvet Science Pty. Ltd. A method of modulating cellular transmigration and agents for use therein
JP4846799B2 (ja) 2005-07-05 2011-12-28 バイオテンプト ベー.フェー. 腫瘍の治療
EP1864692A1 (en) 2006-06-07 2007-12-12 Biotempt B.V. Use of peptides for the control of radiation injury
WO2011036308A1 (en) * 2009-09-28 2011-03-31 Theramab Gmbh Method for preclinical testing of immunomodulatory drugs
CN115466306B (zh) * 2022-01-25 2025-06-27 香港中文大学(深圳) 一种靶向细胞膜表面甲酰肽受体的多肽、药物组合物及其应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9815288A (pt) * 1997-11-13 2001-02-13 Histatek Llc Composição farmacêutica, processos para inibir a desgranulação de mastócitos, para tratar asma em um paciente, para tratar inflamação em um paciente, para inibir a liberação de citocinas em um paciente, para inibir a liberação de histaminas em um paciente, para inibir a liberação de leucotrienos em um paciente, para reduzir a adesão, migração e agregação de linfócitos, eosinófilos e neutrófilos para um sìtio de inflamação em um paciente, para reduzir a produção de anticorpos ige no sìtio de inflamação em um paciente, para inibir a permeabilidade vascular aumentada no sìtio de inflamação em um paciente, e, para tratar inflamação crÈnica em um paciente.

Also Published As

Publication number Publication date
CN1633447A (zh) 2005-06-29
MXPA02003782A (es) 2002-12-13
BR0014742A (pt) 2002-08-27
CZ20021342A3 (cs) 2003-01-15
ZA200202937B (en) 2003-09-23
EA200200451A1 (ru) 2002-10-31
JP2004507441A (ja) 2004-03-11
CN100497374C (zh) 2009-06-10
KR20020057972A (ko) 2002-07-12
CA2387559A1 (en) 2001-04-26
AU8014200A (en) 2001-04-30
NO20021732L (no) 2002-06-12
EP1222199A4 (en) 2003-03-12
WO2001029069A1 (en) 2001-04-26
IL149125A0 (en) 2002-11-10
HUP0203688A2 (hu) 2003-02-28
NO20021732D0 (no) 2002-04-12
EP1222199A1 (en) 2002-07-17

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