PL3533875T3 - Corynebacterium do wytwarzania L-lizyny przez fermentację - Google Patents

Corynebacterium do wytwarzania L-lizyny przez fermentację

Info

Publication number
PL3533875T3
PL3533875T3 PL17844780.1T PL17844780T PL3533875T3 PL 3533875 T3 PL3533875 T3 PL 3533875T3 PL 17844780 T PL17844780 T PL 17844780T PL 3533875 T3 PL3533875 T3 PL 3533875T3
Authority
PL
Poland
Prior art keywords
corynebacterium
lysine
fermentation
producing
Prior art date
Application number
PL17844780.1T
Other languages
English (en)
Inventor
Gang Meng
Aiying WEI
Fengyong MA
Huiping Jia
Jiyin MA
Original Assignee
Ningxia Eppen Biotech Co. Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CN201610800567.6A external-priority patent/CN106318964B/zh
Priority claimed from CN201610800601.XA external-priority patent/CN106367432B/zh
Application filed by Ningxia Eppen Biotech Co. Ltd filed Critical Ningxia Eppen Biotech Co. Ltd
Publication of PL3533875T3 publication Critical patent/PL3533875T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/08Lysine; Diaminopimelic acid; Threonine; Valine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/34Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/15Corynebacterium

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PL17844780.1T 2016-09-01 2017-01-09 Corynebacterium do wytwarzania L-lizyny przez fermentację PL3533875T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201610800567.6A CN106318964B (zh) 2016-09-01 2016-09-01 棒杆菌发酵生产l‑赖氨酸的方法及其启动子改造
CN201610800601.XA CN106367432B (zh) 2016-09-01 2016-09-01 发酵生产l‑赖氨酸的方法及改造的棒杆菌
PCT/CN2017/070629 WO2018040469A1 (zh) 2016-09-01 2017-01-09 发酵生产l-赖氨酸的棒杆菌

Publications (1)

Publication Number Publication Date
PL3533875T3 true PL3533875T3 (pl) 2023-06-12

Family

ID=61299966

Family Applications (1)

Application Number Title Priority Date Filing Date
PL17844780.1T PL3533875T3 (pl) 2016-09-01 2017-01-09 Corynebacterium do wytwarzania L-lizyny przez fermentację

Country Status (8)

Country Link
US (2) US11242545B2 (pl)
EP (1) EP3533875B1 (pl)
JP (1) JP6739651B2 (pl)
CA (1) CA3035466C (pl)
DK (1) DK3533875T5 (pl)
ES (1) ES2939979T3 (pl)
PL (1) PL3533875T3 (pl)
WO (1) WO2018040469A1 (pl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018040469A1 (zh) * 2016-09-01 2018-03-08 宁夏伊品生物科技股份有限公司 发酵生产l-赖氨酸的棒杆菌
KR20230042224A (ko) * 2020-06-08 2023-03-28 이너 몽골리아, 에펜 바이오테크 컴퍼니 리미티드 L-아미노산을 생산하는 재조합 균주 및 이의 구축 방법과 응용
WO2021248890A1 (zh) * 2020-06-08 2021-12-16 黑龙江伊品生物科技有限公司 产l-赖氨酸的重组菌株及其构建方法与应用
CN112662603B (zh) * 2020-11-09 2024-07-02 黑龙江省万里润达生物科技有限公司 一种用于发酵生产l-赖氨酸的基因工程菌及其构建方法
CN114835783B (zh) * 2022-06-01 2024-06-25 宁夏伊品生物科技股份有限公司 NCgl2747基因突变体及其在制备L-赖氨酸中的应用

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0655149B2 (ja) 1985-03-12 1994-07-27 協和醗酵工業株式会社 L―リジンの製造法
MY113040A (en) * 1994-02-24 2001-11-30 Ajinomoto Kk Novel gene derived from coryneform bacteria and use thereof
US5977331A (en) 1994-06-14 1999-11-02 Ajinomoto Co., Inc. α-Ketoglutarate dehydrogenase gene
JP4075087B2 (ja) 1996-12-05 2008-04-16 味の素株式会社 L−リジンの製造法
WO2001023591A1 (en) * 1999-09-30 2001-04-05 Ajinomoto Co., Inc. Process for producing transglutaminase
EP1375664B1 (en) 2001-03-30 2009-11-04 Ajinomoto Co., Inc. Method for the secretion and production of protein
JP2003088380A (ja) * 2001-09-18 2003-03-25 Railway Technical Res Inst ビフェニル又はその誘導体の分解法、及びそれに用いられる微生物
US20080032374A1 (en) 2003-12-18 2008-02-07 Basf Aktiengesellschaft Method for the Preparation of Lysine by Fermentation of Corynebacterium Glutamicum
JP4595506B2 (ja) 2004-11-25 2010-12-08 味の素株式会社 L−アミノ酸生産菌及びl−アミノ酸の製造方法
DE102005032426A1 (de) * 2004-12-18 2006-06-22 Degussa Ag Allele des gnd-Gens aus coryneformen Bakterien
CN101578361A (zh) 2005-06-17 2009-11-11 米克罗比亚精密工程股份有限公司 改进的氨基酸和代谢物生物合成
BRPI0716980A2 (pt) * 2006-09-15 2013-10-22 Cj Cheiljedang Corp Corynebacteria com produtividade de l-lisina aumentada e método de produção da l-lisina usando a mesma
KR100838038B1 (ko) 2006-12-29 2008-06-12 씨제이제일제당 (주) L-라이신 생산능이 향상된 코리네박테리움 속 미생물 및그를 이용한 l-라이신 생산 방법
JP2010110217A (ja) * 2007-02-22 2010-05-20 Ajinomoto Co Inc L−アミノ酸生産菌及びl−アミノ酸の製造法
EP2201126A4 (en) 2007-09-26 2012-05-09 Archer Daniels Midland Co PRODUCTION OF AMINO ACIDS FROM SUCROSE IN <I> CORYNEBACTERIUM GLUTAMICUM </ I>
KR100930203B1 (ko) 2008-01-28 2009-12-07 씨제이제일제당 (주) 개량된 프로모터 및 이를 이용한 l-라이신의 생산 방법
KR101226384B1 (ko) 2010-03-05 2013-01-25 씨제이제일제당 (주) 개량된 프로모터 및 이를 이용한 l-라이신의 생산 방법
BR112014017088B1 (pt) 2012-01-10 2022-04-19 Cj Cheiljedang Corporation Microrganismos de corynebacterium que podem utilizar xilose e método para a produção de l-lisina utilizando os mesmos
CA2900580C (en) 2013-02-08 2022-05-31 Ningxia Eppen Biotech Co., Ltd Method for producing l-lysine by modifying aconitase gene and/or regulatory elements thereof
WO2015060391A1 (ja) * 2013-10-23 2015-04-30 味の素株式会社 目的物質の製造法
CN106367432B (zh) * 2016-09-01 2017-07-18 宁夏伊品生物科技股份有限公司 发酵生产l‑赖氨酸的方法及改造的棒杆菌
WO2018040469A1 (zh) * 2016-09-01 2018-03-08 宁夏伊品生物科技股份有限公司 发酵生产l-赖氨酸的棒杆菌

Also Published As

Publication number Publication date
JP6739651B2 (ja) 2020-08-12
EP3533875A4 (en) 2020-01-22
US11905540B2 (en) 2024-02-20
US20220112529A1 (en) 2022-04-14
EP3533875B1 (en) 2023-02-15
DK3533875T3 (da) 2023-04-03
CA3035466C (en) 2023-08-29
US11242545B2 (en) 2022-02-08
US20190241918A1 (en) 2019-08-08
DK3533875T5 (da) 2024-09-02
WO2018040469A1 (zh) 2018-03-08
JP2019526283A (ja) 2019-09-19
CA3035466A1 (en) 2018-03-08
ES2939979T3 (es) 2023-04-28
EP3533875A1 (en) 2019-09-04

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