PL3533875T3 - Corynebacterium do wytwarzania L-lizyny przez fermentację - Google Patents

Corynebacterium do wytwarzania L-lizyny przez fermentację

Info

Publication number
PL3533875T3
PL3533875T3 PL17844780.1T PL17844780T PL3533875T3 PL 3533875 T3 PL3533875 T3 PL 3533875T3 PL 17844780 T PL17844780 T PL 17844780T PL 3533875 T3 PL3533875 T3 PL 3533875T3
Authority
PL
Poland
Prior art keywords
corynebacterium
lysine
fermentation
producing
Prior art date
Application number
PL17844780.1T
Other languages
English (en)
Inventor
Gang Meng
Aiying WEI
Fengyong MA
Huiping Jia
Jiyin MA
Original Assignee
Ningxia Eppen Biotech Co. Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CN201610800567.6A external-priority patent/CN106318964B/zh
Priority claimed from CN201610800601.XA external-priority patent/CN106367432B/zh
Application filed by Ningxia Eppen Biotech Co. Ltd filed Critical Ningxia Eppen Biotech Co. Ltd
Publication of PL3533875T3 publication Critical patent/PL3533875T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/34—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/15—Corynebacterium

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PL17844780.1T 2016-09-01 2017-01-09 Corynebacterium do wytwarzania L-lizyny przez fermentację PL3533875T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201610800567.6A CN106318964B (zh) 2016-09-01 2016-09-01 棒杆菌发酵生产l‑赖氨酸的方法及其启动子改造
CN201610800601.XA CN106367432B (zh) 2016-09-01 2016-09-01 发酵生产l‑赖氨酸的方法及改造的棒杆菌
PCT/CN2017/070629 WO2018040469A1 (zh) 2016-09-01 2017-01-09 发酵生产l-赖氨酸的棒杆菌

Publications (1)

Publication Number Publication Date
PL3533875T3 true PL3533875T3 (pl) 2023-06-12

Family

ID=61299966

Family Applications (1)

Application Number Title Priority Date Filing Date
PL17844780.1T PL3533875T3 (pl) 2016-09-01 2017-01-09 Corynebacterium do wytwarzania L-lizyny przez fermentację

Country Status (8)

Country Link
US (2) US11242545B2 (pl)
EP (1) EP3533875B1 (pl)
JP (1) JP6739651B2 (pl)
CA (1) CA3035466C (pl)
DK (1) DK3533875T5 (pl)
ES (1) ES2939979T3 (pl)
PL (1) PL3533875T3 (pl)
WO (1) WO2018040469A1 (pl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11242545B2 (en) * 2016-09-01 2022-02-08 Ningxia Eppen Biotech Co., Ltd Corynebacterium for producing L-lysine by fermentation
KR20230042224A (ko) * 2020-06-08 2023-03-28 이너 몽골리아, 에펜 바이오테크 컴퍼니 리미티드 L-아미노산을 생산하는 재조합 균주 및 이의 구축 방법과 응용
JP7644133B2 (ja) * 2020-06-08 2025-03-11 黒竜江伊品生物科技有限公司 L-リジン産生組換え菌株、その構築方法及び使用
CN112662603B (zh) * 2020-11-09 2024-07-02 黑龙江省万里润达生物科技有限公司 一种用于发酵生产l-赖氨酸的基因工程菌及其构建方法
CN114835783B (zh) * 2022-06-01 2024-06-25 宁夏伊品生物科技股份有限公司 NCgl2747基因突变体及其在制备L-赖氨酸中的应用

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0655149B2 (ja) 1985-03-12 1994-07-27 協和醗酵工業株式会社 L―リジンの製造法
MY113040A (en) * 1994-02-24 2001-11-30 Ajinomoto Kk Novel gene derived from coryneform bacteria and use thereof
CN1103819C (zh) 1994-06-14 2003-03-26 味之素株式会社 α-酮戊二酸脱氢酶基因
JP4075087B2 (ja) 1996-12-05 2008-04-16 味の素株式会社 L−リジンの製造法
ATE532870T1 (de) 1999-09-30 2011-11-15 Ajinomoto Kk Verfahren zur herstellung von transglutaminase
DE60234247D1 (de) 2001-03-30 2009-12-17 Ajinomoto Kk Verfahren zur sekretion und produktion von protein
JP2003088380A (ja) * 2001-09-18 2003-03-25 Railway Technical Res Inst ビフェニル又はその誘導体の分解法、及びそれに用いられる微生物
EP1939296A3 (en) 2003-12-18 2010-08-25 Basf Se Methods for the preparation of a fine chemical by fermentation
JP4595506B2 (ja) 2004-11-25 2010-12-08 味の素株式会社 L−アミノ酸生産菌及びl−アミノ酸の製造方法
DE102005032426A1 (de) * 2004-12-18 2006-06-22 Degussa Ag Allele des gnd-Gens aus coryneformen Bakterien
CN101578361A (zh) 2005-06-17 2009-11-11 米克罗比亚精密工程股份有限公司 改进的氨基酸和代谢物生物合成
EP3170889A1 (en) * 2006-09-15 2017-05-24 CJ Cheiljedang Corporation A corynebacteria having enhanced l-lysine productivity and a method of producing l-lysine using the same
KR100838038B1 (ko) * 2006-12-29 2008-06-12 씨제이제일제당 (주) L-라이신 생산능이 향상된 코리네박테리움 속 미생물 및그를 이용한 l-라이신 생산 방법
JP2010110217A (ja) * 2007-02-22 2010-05-20 Ajinomoto Co Inc L−アミノ酸生産菌及びl−アミノ酸の製造法
BRPI0817698A2 (pt) 2007-09-26 2014-11-25 Archer Daniels Midland Co Produção de aminoácidos a partir de sacarose em corynebacterium glutamicum
KR100930203B1 (ko) 2008-01-28 2009-12-07 씨제이제일제당 (주) 개량된 프로모터 및 이를 이용한 l-라이신의 생산 방법
KR101226384B1 (ko) 2010-03-05 2013-01-25 씨제이제일제당 (주) 개량된 프로모터 및 이를 이용한 l-라이신의 생산 방법
JP5945336B2 (ja) 2012-01-10 2016-07-05 シージェイ チェイルジェダン コーポレイション キシロース利用能が付与されたコリネバクテリウム属微生物、及びそれを用いたl−リジンの生産方法
US20160002684A1 (en) 2013-02-08 2016-01-07 Ningxia Eppen Biotech Co., Ltd Method for Producing L-Lysine by Modifying Aconitase Gene and/or Regulatory Elements thereof
EP3061828B1 (en) * 2013-10-23 2024-08-28 Ajinomoto Co., Inc. Method for producing target substance
CN106367432B (zh) * 2016-09-01 2017-07-18 宁夏伊品生物科技股份有限公司 发酵生产l‑赖氨酸的方法及改造的棒杆菌
US11242545B2 (en) * 2016-09-01 2022-02-08 Ningxia Eppen Biotech Co., Ltd Corynebacterium for producing L-lysine by fermentation

Also Published As

Publication number Publication date
WO2018040469A1 (zh) 2018-03-08
ES2939979T3 (es) 2023-04-28
US20190241918A1 (en) 2019-08-08
US11242545B2 (en) 2022-02-08
DK3533875T5 (da) 2024-09-02
EP3533875A1 (en) 2019-09-04
CA3035466C (en) 2023-08-29
CA3035466A1 (en) 2018-03-08
DK3533875T3 (da) 2023-04-03
EP3533875B1 (en) 2023-02-15
US11905540B2 (en) 2024-02-20
JP6739651B2 (ja) 2020-08-12
US20220112529A1 (en) 2022-04-14
JP2019526283A (ja) 2019-09-19
EP3533875A4 (en) 2020-01-22

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