PL3455222T3 - Środki do obrazowania jądrowego oraz radioterapeutyki celujące w anhydrazę węglanową IX oraz ich zastosowania - Google Patents
Środki do obrazowania jądrowego oraz radioterapeutyki celujące w anhydrazę węglanową IX oraz ich zastosowaniaInfo
- Publication number
- PL3455222T3 PL3455222T3 PL17796928T PL17796928T PL3455222T3 PL 3455222 T3 PL3455222 T3 PL 3455222T3 PL 17796928 T PL17796928 T PL 17796928T PL 17796928 T PL17796928 T PL 17796928T PL 3455222 T3 PL3455222 T3 PL 3455222T3
- Authority
- PL
- Poland
- Prior art keywords
- carbonic anhydrase
- nuclear imaging
- agents targeting
- radiotherapeutics
- targeting carbonic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0446—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0453—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
- C07F1/08—Copper compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/06—Aluminium compounds
- C07F5/069—Aluminium compounds without C-aluminium linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Physics & Mathematics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662336043P | 2016-05-13 | 2016-05-13 | |
| EP17796928.4A EP3455222B1 (en) | 2016-05-13 | 2017-05-12 | Nuclear imaging and radiotherapeutics agents targeting carbonic anhydrase ix and uses thereof |
| PCT/US2017/032384 WO2017197251A1 (en) | 2016-05-13 | 2017-05-12 | Nuclear imaging and radiotherapeutics agents targeting carbonic anhydrase ix and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3455222T3 true PL3455222T3 (pl) | 2022-07-11 |
Family
ID=60266891
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL17796928T PL3455222T3 (pl) | 2016-05-13 | 2017-05-12 | Środki do obrazowania jądrowego oraz radioterapeutyki celujące w anhydrazę węglanową IX oraz ich zastosowania |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20190192699A1 (pl) |
| EP (1) | EP3455222B1 (pl) |
| JP (1) | JP7030061B2 (pl) |
| KR (1) | KR102531494B1 (pl) |
| CN (1) | CN109476655B (pl) |
| AU (1) | AU2017263630B2 (pl) |
| DK (1) | DK3455222T3 (pl) |
| ES (1) | ES2912947T3 (pl) |
| LT (1) | LT3455222T (pl) |
| PL (1) | PL3455222T3 (pl) |
| WO (1) | WO2017197251A1 (pl) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11524082B2 (en) * | 2017-08-22 | 2022-12-13 | Purdue Research Foundation | FBSA-based therapeutic and radioimaging conjugates targeting carbonic anhydrase positive cancers |
| KR20210052435A (ko) * | 2018-08-30 | 2021-05-10 | 니혼 메디피직스 가부시키가이샤 | 방사성 이미다조티아디아졸 유도체 화합물 |
| CA3243979A1 (en) * | 2022-02-11 | 2025-04-30 | C-Biomex Co., Ltd. | Peptide ligand targeting carbonic anhydrase IX, peptide construction comprising it, and associated uses |
| CN117186087A (zh) * | 2022-02-15 | 2023-12-08 | 无锡诺宇医药科技有限公司 | 碳酸酐酶ix靶向放射性诊疗药物及其制备方法 |
| CN118812636B (zh) * | 2023-04-21 | 2025-12-23 | 中国科学院上海应用物理研究所 | 一种多肽类化合物、含其的药物组合物及其应用 |
| WO2025044924A1 (zh) * | 2023-08-25 | 2025-03-06 | 无锡诺宇医药科技有限公司 | 靶向碳酸酐酶放射性药物 |
| WO2025106958A1 (en) * | 2023-11-17 | 2025-05-22 | The Johns Hopkins University | A simplified and more accessible method for production of 111inin-xyimsr-01 for patient use |
| CN117659128B (zh) * | 2023-11-30 | 2024-07-02 | 北京大学第一医院 | 一种碳酸酐酶ix靶向化合物及应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20090127433A (ko) * | 2007-04-05 | 2009-12-11 | 지멘스 메디컬 솔루션즈 유에스에이, 인크. | 클릭 화학을 이용한 탄산탈수효소―ⅰⅹ에 대한 분자 영상화 프로브의 제조 |
| CN102083427B (zh) * | 2008-01-09 | 2014-12-10 | 分子洞察制药公司 | 碳酸酐酶ix的抑制剂 |
| CN103687854A (zh) * | 2011-05-09 | 2014-03-26 | 文森医学公司 | 碳酸酐酶靶向剂及其使用方法 |
| CA3151947A1 (en) * | 2014-02-03 | 2015-08-06 | Eidgenoessische Technische Hochschule Zuerich | Low molecular weight drug conjugates for binding to carbonic anhydrase ix |
| WO2016196628A1 (en) * | 2015-06-01 | 2016-12-08 | The Johns Hopkins University | Nuclear imaging and radiotherapeutics agents targeting carbonic anhydrase ix and uses thereof |
-
2017
- 2017-05-12 PL PL17796928T patent/PL3455222T3/pl unknown
- 2017-05-12 AU AU2017263630A patent/AU2017263630B2/en active Active
- 2017-05-12 CN CN201780043433.7A patent/CN109476655B/zh active Active
- 2017-05-12 ES ES17796928T patent/ES2912947T3/es active Active
- 2017-05-12 JP JP2018558351A patent/JP7030061B2/ja active Active
- 2017-05-12 WO PCT/US2017/032384 patent/WO2017197251A1/en not_active Ceased
- 2017-05-12 EP EP17796928.4A patent/EP3455222B1/en active Active
- 2017-05-12 DK DK17796928.4T patent/DK3455222T3/da active
- 2017-05-12 LT LTEPPCT/US2017/032384T patent/LT3455222T/lt unknown
- 2017-05-12 KR KR1020187035954A patent/KR102531494B1/ko active Active
- 2017-05-12 US US16/301,338 patent/US20190192699A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CN109476655B (zh) | 2022-03-08 |
| KR20180136567A (ko) | 2018-12-24 |
| CN109476655A (zh) | 2019-03-15 |
| US20190192699A1 (en) | 2019-06-27 |
| EP3455222A4 (en) | 2019-12-18 |
| JP7030061B2 (ja) | 2022-03-04 |
| AU2017263630B2 (en) | 2021-11-04 |
| WO2017197251A1 (en) | 2017-11-16 |
| CA3024097A1 (en) | 2017-11-16 |
| AU2017263630A1 (en) | 2018-11-22 |
| ES2912947T3 (es) | 2022-05-30 |
| JP2019514984A (ja) | 2019-06-06 |
| EP3455222B1 (en) | 2022-03-02 |
| AU2017263630A8 (en) | 2019-01-17 |
| EP3455222A1 (en) | 2019-03-20 |
| LT3455222T (lt) | 2022-06-27 |
| DK3455222T3 (da) | 2022-05-23 |
| KR102531494B1 (ko) | 2023-05-10 |
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