PL3448848T3 - Postać polimorficzna N-{6-(2-hydroksypropan-2-ylo)-2-[2-(metylosulfonylo)etylo]-2H-indazol-5-ilo}-6-(trifluorometylo)pirydyno-2-karboksyamidu - Google Patents

Postać polimorficzna N-{6-(2-hydroksypropan-2-ylo)-2-[2-(metylosulfonylo)etylo]-2H-indazol-5-ilo}-6-(trifluorometylo)pirydyno-2-karboksyamidu

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Publication number
PL3448848T3
PL3448848T3 PL17718560.0T PL17718560T PL3448848T3 PL 3448848 T3 PL3448848 T3 PL 3448848T3 PL 17718560 T PL17718560 T PL 17718560T PL 3448848 T3 PL3448848 T3 PL 3448848T3
Authority
PL
Poland
Prior art keywords
methylsulphonyl
hydroxypropan
indazol
carboxamide
trifluoromethyl
Prior art date
Application number
PL17718560.0T
Other languages
English (en)
Inventor
Tobias THALER
Johannes Platzek
Nicolas GUIMOND
Original Assignee
Bayer Pharma Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Pharma Aktiengesellschaft filed Critical Bayer Pharma Aktiengesellschaft
Publication of PL3448848T3 publication Critical patent/PL3448848T3/pl

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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/86—Hydrazides; Thio or imino analogues thereof
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    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
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    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
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PL17718560.0T 2016-04-29 2017-04-25 Postać polimorficzna N-{6-(2-hydroksypropan-2-ylo)-2-[2-(metylosulfonylo)etylo]-2H-indazol-5-ilo}-6-(trifluorometylo)pirydyno-2-karboksyamidu PL3448848T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16167652 2016-04-29
PCT/EP2017/059767 WO2017186703A1 (en) 2016-04-29 2017-04-25 Polymorphic form of n-{6-(2-hydroxypropan-2-yl)-2-[2-(methylsulphonyl)ethyl]-2h-indazol-5-yl}-6-(trifluoromethyl)pyridine-2-carboxamide

Publications (1)

Publication Number Publication Date
PL3448848T3 true PL3448848T3 (pl) 2024-03-11

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PL17718560.0T PL3448848T3 (pl) 2016-04-29 2017-04-25 Postać polimorficzna N-{6-(2-hydroksypropan-2-ylo)-2-[2-(metylosulfonylo)etylo]-2H-indazol-5-ilo}-6-(trifluorometylo)pirydyno-2-karboksyamidu
PL17718558T PL3448846T3 (pl) 2016-04-29 2017-04-25 Synteza indazoli

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US (2) US10759758B2 (pl)
EP (4) EP4275754A3 (pl)
JP (2) JP6954924B2 (pl)
KR (2) KR102373220B1 (pl)
CN (3) CN109415340B (pl)
AR (1) AR108245A1 (pl)
AU (2) AU2017256626B2 (pl)
CA (1) CA3022324C (pl)
CL (2) CL2018003087A1 (pl)
CO (2) CO2018011644A2 (pl)
CU (1) CU20180131A7 (pl)
DK (2) DK3448848T3 (pl)
DO (1) DOP2018000237A (pl)
EA (2) EA038035B1 (pl)
EC (1) ECSP18081437A (pl)
ES (2) ES2883298T3 (pl)
FI (1) FI3448848T3 (pl)
GE (1) GEP20217214B (pl)
HR (2) HRP20211072T1 (pl)
HU (2) HUE056460T2 (pl)
IL (2) IL262414B2 (pl)
JO (2) JOP20170099B1 (pl)
LT (2) LT3448848T (pl)
MA (1) MA44759B1 (pl)
MX (2) MX380032B (pl)
MY (2) MY190319A (pl)
NI (1) NI201800112A (pl)
PE (1) PE20190107A1 (pl)
PH (1) PH12018502289B1 (pl)
PL (2) PL3448848T3 (pl)
PT (2) PT3448846T (pl)
RS (2) RS62112B1 (pl)
SA (1) SA518400333B1 (pl)
SG (2) SG11201808108XA (pl)
SI (2) SI3448848T1 (pl)
SV (1) SV2018005775A (pl)
TN (1) TN2018000352A1 (pl)
TW (2) TWI657084B (pl)
UA (2) UA123169C2 (pl)
UY (2) UY37216A (pl)
WO (2) WO2017186703A1 (pl)
ZA (1) ZA201808057B (pl)

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SI3448848T1 (sl) * 2016-04-29 2024-01-31 Bayer Pharma Aktiengesellschaft Polimorfna oblika N-(6-(2-hidroksipropan-2-il)-2-(2-(metilsulfonil)etil)-2H-indazol-5-il) -6-(trifluormetil)piridin-2-karboksamida
PE20240651A1 (es) 2016-04-29 2024-04-04 Bayer Pharma AG Sintesis de indazoles
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JOP20180011A1 (ar) 2017-02-16 2019-01-30 Gilead Sciences Inc مشتقات بيرولو [1، 2-b]بيريدازين
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