PL3351620T3 - Hodowla komórek zoptymalizowana metabolicznie - Google Patents

Hodowla komórek zoptymalizowana metabolicznie

Info

Publication number
PL3351620T3
PL3351620T3 PL18161278T PL18161278T PL3351620T3 PL 3351620 T3 PL3351620 T3 PL 3351620T3 PL 18161278 T PL18161278 T PL 18161278T PL 18161278 T PL18161278 T PL 18161278T PL 3351620 T3 PL3351620 T3 PL 3351620T3
Authority
PL
Poland
Prior art keywords
cell culture
optimized cell
metabolically optimized
metabolically
culture
Prior art date
Application number
PL18161278T
Other languages
English (en)
Polish (pl)
Inventor
Shawn Lawrence
Ann KIM
Amy Johnson
Original Assignee
Regeneron Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=52813657&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL3351620(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Regeneron Pharmaceuticals, Inc. filed Critical Regeneron Pharmaceuticals, Inc.
Publication of PL3351620T3 publication Critical patent/PL3351620T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
    • C12N5/12Fused cells, e.g. hybridomas
    • C12N5/16Animal cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0681Cells of the genital tract; Non-germinal cells from gonads
    • C12N5/0682Cells of the female genital tract, e.g. endometrium; Non-germinal cells from ovaries, e.g. ovarian follicle cells
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/10Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14Specific host cells or culture conditions, e.g. components, pH or temperature
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/60Buffer, e.g. pH regulation, osmotic pressure
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2511/00Cells for large scale production

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Reproductive Health (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Peptides Or Proteins (AREA)
PL18161278T 2013-10-11 2014-10-10 Hodowla komórek zoptymalizowana metabolicznie PL3351620T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201361889815P 2013-10-11 2013-10-11
EP14851841.8A EP3055409B1 (en) 2013-10-11 2014-10-10 Metabolically optimized cell culture
PCT/US2014/059993 WO2015054554A1 (en) 2013-10-11 2014-10-10 Metabolically optimized cell culture
EP18161278.9A EP3351620B1 (en) 2013-10-11 2014-10-10 Metabolically optimized cell culture

Publications (1)

Publication Number Publication Date
PL3351620T3 true PL3351620T3 (pl) 2021-03-08

Family

ID=52813657

Family Applications (2)

Application Number Title Priority Date Filing Date
PL18161278T PL3351620T3 (pl) 2013-10-11 2014-10-10 Hodowla komórek zoptymalizowana metabolicznie
PL14851841T PL3055409T3 (pl) 2013-10-11 2014-10-10 Metabolicznie zoptymalizowana hodowla komórkowa

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL14851841T PL3055409T3 (pl) 2013-10-11 2014-10-10 Metabolicznie zoptymalizowana hodowla komórkowa

Country Status (17)

Country Link
US (2) US20160244725A1 (enExample)
EP (3) EP3351620B1 (enExample)
JP (3) JP6663854B2 (enExample)
KR (4) KR102510238B1 (enExample)
CN (2) CN114717196A (enExample)
AU (2) AU2014331776B2 (enExample)
CA (1) CA2926049C (enExample)
DK (2) DK3055409T3 (enExample)
EA (2) EA033783B1 (enExample)
ES (2) ES2833471T3 (enExample)
HU (2) HUE051049T2 (enExample)
IL (2) IL244511A0 (enExample)
MX (2) MX376623B (enExample)
PL (2) PL3351620T3 (enExample)
SG (2) SG10201800772TA (enExample)
WO (1) WO2015054554A1 (enExample)
ZA (1) ZA201601550B (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11390663B2 (en) 2013-10-11 2022-07-19 Regeneron Pharmaceuticals, Inc. Metabolically optimized cell culture
MX376623B (es) 2013-10-11 2025-03-07 Regeneron Pharma Cultivo celular metabolicamente optimizado.
US20160244726A1 (en) * 2013-10-11 2016-08-25 Regeneron Pharmaceuticals, Inc. Metabolically optimized cell culture
JP7260018B2 (ja) * 2017-03-31 2023-04-18 株式会社三洋物産 遊技機
JP7260020B2 (ja) * 2017-03-31 2023-04-18 株式会社三洋物産 遊技機
JP7260011B2 (ja) * 2017-03-31 2023-04-18 株式会社三洋物産 遊技機
JP7310945B2 (ja) * 2017-04-27 2023-07-19 株式会社三洋物産 遊技機
JP7310952B2 (ja) * 2017-04-27 2023-07-19 株式会社三洋物産 遊技機
JP7310947B2 (ja) * 2017-04-27 2023-07-19 株式会社三洋物産 遊技機
JP7272480B2 (ja) * 2017-04-27 2023-05-12 株式会社三洋物産 遊技機
JP7260013B2 (ja) * 2017-04-27 2023-04-18 株式会社三洋物産 遊技機
JP7260021B2 (ja) * 2017-04-27 2023-04-18 株式会社三洋物産 遊技機
JP7260009B2 (ja) * 2017-04-27 2023-04-18 株式会社三洋物産 遊技機
JP7260012B2 (ja) * 2017-04-27 2023-04-18 株式会社三洋物産 遊技機
IL273549B2 (en) 2017-10-06 2023-10-01 Lonza Ag Automated control of cell culture using Raman spectroscopy
ES2919850T3 (es) 2017-10-16 2022-07-28 Regeneron Pharma Procedimientos de perfusión
WO2019106097A1 (en) * 2017-11-30 2019-06-06 F.Hoffmann-La Roche Ag Process for culturing mammalian cells
KR20200135510A (ko) * 2018-03-29 2020-12-02 제넨테크, 인크. 포유류 세포들에서 젖분비자극 활성의 조절
GB201810772D0 (en) 2018-06-29 2018-08-15 Ge Healthcare Bio Sciences Ab Method in bioprocess purification system
JP7231355B2 (ja) * 2018-08-22 2023-03-01 日機装株式会社 細胞培養方法および細胞培養装置
MY204234A (en) 2018-08-27 2024-08-16 Regeneron Pharma Use of raman spectroscopy in downstream purification
JP2020151560A (ja) * 2020-06-24 2020-09-24 株式会社三洋物産 遊技機
JP2020151559A (ja) * 2020-06-24 2020-09-24 株式会社三洋物産 遊技機
EP3985097A1 (en) * 2020-10-14 2022-04-20 Sartorius Stedim Biotech GmbH A method and system for configuring and/or setup of a downstream process for processing a biomass

Family Cites Families (26)

* Cited by examiner, † Cited by third party
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US5703055A (en) 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
KR970029803A (ko) 1995-11-03 1997-06-26 김광호 반도체 메모리장치의 프리차지 회로
US6165741A (en) 1997-05-30 2000-12-26 The Trustees Of The University Of Pennsylvania Method for rapid detection of bacterial growth in cultures
US5972650A (en) 1997-06-26 1999-10-26 Brigham And Women's Hospital Tetracycline repressor regulated mammalian cell transcription and viral replication switch
DE60211329T2 (de) 2001-01-16 2007-05-24 Regeneron Pharmaceuticals, Inc. Isolierung von sezernierte proteine exprimierenden zellen
US6953692B2 (en) * 2001-12-18 2005-10-11 Bayer Pharmaceuticals Corporation Device and method for seed-train expansion of mammalian cells
CA2417689C (en) 2002-03-05 2006-05-09 F. Hoffmann-La Roche Ag Improved methods for growing mammalian cells in vitro
US7039770B1 (en) 2002-03-05 2006-05-02 Juniper Networks, Inc. Low latency request dispatcher
US8673589B2 (en) 2002-05-29 2014-03-18 Regeneron Pharmaceuticals, Inc. Inducible eukaryotic expression system
DK1623019T4 (en) 2003-05-15 2017-03-27 Wyeth Llc LIMITED GLUCOSE SUPPLY TO ANIMAL CELL CULTURE
US7531327B2 (en) * 2004-07-23 2009-05-12 Immunomedics, Inc. Methods and compositions for increasing longevity and protein yield from a cell culture
TWI364458B (en) * 2004-08-27 2012-05-21 Wyeth Res Ireland Ltd Production of tnfr-lg
US7335491B2 (en) 2004-08-27 2008-02-26 Wyeth Research Ireland Limited Production of anti-abeta
CN101300342A (zh) * 2005-11-02 2008-11-05 惠氏公司 用于使哺乳动物细胞具备适应性的方法
US10155816B2 (en) 2005-11-28 2018-12-18 Genmab A/S Recombinant monovalent antibodies and methods for production thereof
US7575890B2 (en) 2006-01-18 2009-08-18 Oxygen Enterprises, Ltd. Method for rapid detection and evaluation of cultured cell growth
EP2064315B1 (en) 2006-11-03 2015-05-13 Wyeth LLC Glycolysis-inhibiting substances in cell culture
US7771997B2 (en) 2007-06-04 2010-08-10 Regeneron Pharmaceuticals, Inc. Enhanced expression and stability regions
EP2188371B1 (en) 2007-08-09 2017-12-20 Wyeth LLC Use of perfusion to enhance production of fed-batch cell culture in bioreactors
EP2331678B1 (en) * 2008-06-13 2015-09-30 Janssen Biotech, Inc. Methods for obtaining high viable cell density in mammalian cell culture
US8470552B2 (en) * 2009-10-12 2013-06-25 Keck Graduate Institute Strategy to reduce lactic acid production and control PH in animal cell culture
CN102858952B (zh) * 2010-04-26 2015-10-14 诺瓦提斯公司 改进的细胞培养基
KR20190067277A (ko) * 2010-05-28 2019-06-14 제넨테크, 인크. 락테이트 데히드로게나제 및 피루베이트 데히드로게나제 키나제의 발현의 하향조절에 의한 락테이트 수준의 감소 및 폴리펩티드 생산의 증가
TWI637057B (zh) 2012-11-09 2018-10-01 拜爾沙納有限公司 具交替生物反應器用途之不連續進料批次製程
US20140199728A1 (en) * 2013-01-14 2014-07-17 Amgen Inc. Methods of using cell-cycle inhibitors to modulate one or more properties of a cell culture
MX376623B (es) 2013-10-11 2025-03-07 Regeneron Pharma Cultivo celular metabolicamente optimizado.

Also Published As

Publication number Publication date
US20210087535A1 (en) 2021-03-25
KR20210046835A (ko) 2021-04-28
DK3351620T3 (da) 2020-10-26
PL3055409T3 (pl) 2018-10-31
MX2020011334A (es) 2021-07-30
IL244511A0 (en) 2016-04-21
EA201991976A1 (ru) 2020-04-02
MX2016004564A (es) 2016-07-12
AU2021200193B2 (en) 2023-08-24
EP3351620B1 (en) 2020-09-02
CN114717196A (zh) 2022-07-08
HK1223122A1 (en) 2017-07-21
HUE051049T2 (hu) 2021-01-28
JP6663854B2 (ja) 2020-03-13
SG10201800772TA (en) 2018-03-28
KR20230038324A (ko) 2023-03-17
KR102358807B1 (ko) 2022-02-08
EA201690600A1 (ru) 2016-09-30
SG11201601681QA (en) 2016-04-28
EP3055409A4 (en) 2016-09-28
KR102510238B1 (ko) 2023-03-16
KR102610425B1 (ko) 2023-12-06
MX384960B (es) 2025-03-14
AU2014331776A1 (en) 2016-03-24
JP2020072760A (ja) 2020-05-14
EP3351620A1 (en) 2018-07-25
AU2014331776B2 (en) 2020-10-22
CA2926049C (en) 2023-09-05
EA033783B1 (ru) 2019-11-25
US20160244725A1 (en) 2016-08-25
JP2016532457A (ja) 2016-10-20
HK1253275A1 (en) 2019-06-14
JP2022009453A (ja) 2022-01-14
EP3055409A1 (en) 2016-08-17
DK3055409T3 (en) 2018-07-30
JP7377243B2 (ja) 2023-11-09
MX376623B (es) 2025-03-07
KR20160062032A (ko) 2016-06-01
WO2015054554A1 (en) 2015-04-16
ZA201601550B (en) 2023-05-31
CN105637085A (zh) 2016-06-01
ES2833471T3 (es) 2021-06-15
JP6967620B2 (ja) 2021-11-17
EP3812453A1 (en) 2021-04-28
HUE039551T2 (hu) 2019-01-28
CA2926049A1 (en) 2015-04-16
ES2678945T3 (es) 2018-08-21
EP3055409B1 (en) 2018-04-25
IL262833A (en) 2018-12-31
AU2021200193A1 (en) 2021-03-18
KR102243980B1 (ko) 2021-04-26
KR20220020415A (ko) 2022-02-18

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