PL3310340T3 - Formulacje o wysokim stężeniu - Google Patents

Formulacje o wysokim stężeniu

Info

Publication number
PL3310340T3
PL3310340T3 PL16733703.9T PL16733703T PL3310340T3 PL 3310340 T3 PL3310340 T3 PL 3310340T3 PL 16733703 T PL16733703 T PL 16733703T PL 3310340 T3 PL3310340 T3 PL 3310340T3
Authority
PL
Poland
Prior art keywords
high concentration
concentration formulations
formulations
concentration
Prior art date
Application number
PL16733703.9T
Other languages
English (en)
Inventor
Luigi Maria Longo
Original Assignee
Cassiopea S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=53491322&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL3310340(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cassiopea S.P.A. filed Critical Cassiopea S.P.A.
Publication of PL3310340T3 publication Critical patent/PL3310340T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/14Drugs for dermatological disorders for baldness or alopecia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/28Antiandrogens
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
PL16733703.9T 2015-06-22 2016-06-20 Formulacje o wysokim stężeniu PL3310340T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562182988P 2015-06-22 2015-06-22
EP15173860.6A EP3108879A1 (en) 2015-06-25 2015-06-25 High concentration formulation
PCT/IB2016/053662 WO2016207778A1 (en) 2015-06-22 2016-06-20 High concentration formulation

Publications (1)

Publication Number Publication Date
PL3310340T3 true PL3310340T3 (pl) 2026-02-16

Family

ID=53491322

Family Applications (1)

Application Number Title Priority Date Filing Date
PL16733703.9T PL3310340T3 (pl) 2015-06-22 2016-06-20 Formulacje o wysokim stężeniu

Country Status (22)

Country Link
US (6) US10603327B2 (pl)
EP (3) EP3108879A1 (pl)
JP (4) JP6916744B2 (pl)
KR (1) KR102636936B1 (pl)
CN (1) CN107979999B (pl)
AU (1) AU2016284935B2 (pl)
BR (1) BR112017027721A2 (pl)
CA (1) CA2987701C (pl)
DK (1) DK3310340T3 (pl)
ES (1) ES3056907T3 (pl)
FI (1) FI3310340T3 (pl)
HR (1) HRP20251498T1 (pl)
LT (1) LT3310340T (pl)
MX (1) MX391040B (pl)
PL (1) PL3310340T3 (pl)
PT (1) PT3310340T (pl)
RS (1) RS67597B1 (pl)
RU (1) RU2731564C2 (pl)
SI (1) SI3310340T1 (pl)
SM (1) SMT202600032T1 (pl)
WO (1) WO2016207778A1 (pl)
ZA (1) ZA201708173B (pl)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20071616A1 (it) 2007-08-03 2009-02-04 Cosmo Spa Processo enzimatico per l'ottenimento di 17-alfa monoesteri del cortexolone e/o suoi 9,11-deidroderivati.
EP3108879A1 (en) 2015-06-25 2016-12-28 Cassiopea S.p.A. High concentration formulation
CN115068423A (zh) * 2021-03-12 2022-09-20 浙江万晟药业有限公司 一种克拉司酮泡沫剂及其制备方法
CN113425845B (zh) * 2021-08-10 2022-12-02 成都倍特药业股份有限公司 一种预防和/或治疗脱发症的传递体制剂及其制备方法和用途
TW202444338A (zh) 2023-04-07 2024-11-16 義大利商卡斯歐皮亞股份公司 克拉司酮與米諾地爾之組合療法
CN121057583A (zh) * 2023-04-07 2025-12-02 安普力菲卡控股集团公司 用于治疗雄激素性脱发的组合物和方法
WO2025068281A1 (en) 2023-09-26 2025-04-03 Cassiopea S.P.A. CORTEXOLONE-17α-PROPIONATE FOR TREATING ACNEIFORM ERUPTIONS
EP4529925A1 (en) 2023-09-26 2025-04-02 Cassiopea S.p.A. Cortexolone-17-alpha- propionate for treating acneiform eruptions
WO2025094021A1 (en) * 2023-10-31 2025-05-08 Lupin Limited Stable topical cream formulation of clascoterone
WO2025125508A1 (en) 2023-12-14 2025-06-19 Cassiopea S.P.A. Cortexolone-17αlpha-propionate combinations for treating acne
US20250213594A1 (en) * 2023-12-27 2025-07-03 Inventage Lab Inc. Novel long-acting injectable composition for preventing or treating androgenetic alopecia containing finasteride
WO2025172818A1 (en) 2024-02-14 2025-08-21 Cassiopea S.P.A. Pyrilutamide combination therapy
WO2026057588A1 (en) 2024-09-10 2026-03-19 Cassiopea S.P.A. Clascoterone and minoxidil combination therapy for use in treating hair loss

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CH429716A (de) 1961-06-24 1967-02-15 Vismara Francesco Spa Verfahren zur Herstellung von 17a-Acyloxy-21-hydroxy-Steroiden
NL6605514A (pl) 1966-04-25 1967-10-26
NL6605515A (pl) 1966-04-25 1967-10-26
US3780177A (en) 1967-06-16 1973-12-18 Warner Lambert Co 17-butyrate,21-ester derivatives of 6alpha,9alpha-difluoroprednisolone,compositions and use
US3733318A (en) 1972-03-23 1973-05-15 Syntex Corp 21-orthoesters of cortical steroids and methods of preparing same
JPS5910799B2 (ja) 1975-07-15 1984-03-12 大正製薬株式会社 プレグナン系ステロイド 17−エステル類の製法
DE3243482A1 (de) 1982-11-22 1984-05-24 Schering AG, 1000 Berlin und 4709 Bergkamen Neue 6(alpha)-methylkortikoide, ihre herstellung und verwendung
DE3402330A1 (de) 1984-01-20 1985-07-25 Schering AG, 1000 Berlin und 4709 Bergkamen 1(alpha),2(alpha)-methylen-6-methylen- und 6(alpha)-methyl-pregnene, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate
US4920216A (en) 1987-05-28 1990-04-24 The Trustees Of Columbia In The City Of New York Selective chlorination of steroids and other substrates directed by covalently linked pyridine derivatives acting as templates
US5264428A (en) 1990-02-16 1993-11-23 Kanoldt Arzneimittel Gmbh Use of stigmasta-4-en-3-one in the treatment of androgen dependent diseases
DE19653730C2 (de) 1996-12-11 1999-06-24 Schering Ag Immobilisierte Proteine aus Rohextrakt und deren Verwendung zur Umsetzung von Estern
JP3992297B2 (ja) 1997-06-25 2007-10-17 帝人株式会社 ビタミンd3誘導体、およびそれを用いる炎症性呼吸器疾患治療剤
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ITMI20011762A1 (it) 2001-08-10 2003-02-10 Cosmo Spa Esteri di 17alfa,21-diidrossipregnene, loro uso come agenti anti-androgenetici e procedimenti per la loro preparazione
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ITMI20051695A1 (it) 2005-09-14 2007-03-15 Cosmo Spa Uso di 17a-esteri c3-c10 del 9,11-deidrocortexolone cme agenti anti-gonadotropinici
ITMI20071616A1 (it) 2007-08-03 2009-02-04 Cosmo Spa Processo enzimatico per l'ottenimento di 17-alfa monoesteri del cortexolone e/o suoi 9,11-deidroderivati.
AU2014233577B2 (en) * 2007-08-03 2016-03-03 Cassiopea S.P.A. Enzymatic process for obtaining 17 alpha-monoesters of cortexolone and/or its 9,11-dehydroderivatives
WO2011029392A1 (en) * 2009-09-10 2011-03-17 Youzhi Tong Androgen receptor antagonists and uses thereof
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HK1207961A1 (zh) * 2011-11-25 2016-02-19 阿德里安娜‧贾内尔‧杰克逊 用於增加毛髮生長和/或預防毛髮損失的油組合物和方法
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ITMI20132157A1 (it) 2013-12-20 2015-06-21 Cosmo Dermatos Srl Cortexolone 17alfa-propionate for use in the treatment of skin wounds and/or atrophic skin disorders . cortexolone 17alfa-propionato per uso nel trattamento delle ferite della pelle e/o disordini atrofici della pelle.
EP3108879A1 (en) 2015-06-25 2016-12-28 Cassiopea S.p.A. High concentration formulation

Also Published As

Publication number Publication date
EP4650000A2 (en) 2025-11-19
RU2018101870A (ru) 2019-07-23
US20200222429A1 (en) 2020-07-16
MX2017017119A (es) 2018-08-01
US20220193093A1 (en) 2022-06-23
US20180169113A1 (en) 2018-06-21
LT3310340T (lt) 2026-02-10
KR102636936B1 (ko) 2024-02-16
US20190282589A1 (en) 2019-09-19
AU2016284935B2 (en) 2021-07-01
JP2023027273A (ja) 2023-03-01
RS67597B1 (sr) 2026-01-30
EP3108879A1 (en) 2016-12-28
BR112017027721A2 (pt) 2018-09-11
RU2018101870A3 (pl) 2019-11-25
US20190374553A1 (en) 2019-12-12
SMT202600032T1 (it) 2026-03-09
CN107979999A (zh) 2018-05-01
MX391040B (es) 2025-03-21
ES3056907T3 (en) 2026-02-25
US10980819B2 (en) 2021-04-20
JP2021169508A (ja) 2021-10-28
ZA201708173B (en) 2021-03-31
SI3310340T1 (sl) 2026-02-27
JP2018524325A (ja) 2018-08-30
RU2731564C2 (ru) 2020-09-04
PT3310340T (pt) 2025-12-02
CA2987701A1 (en) 2016-12-29
JP2024069534A (ja) 2024-05-21
US20240189324A1 (en) 2024-06-13
JP7458464B2 (ja) 2024-03-29
CN107979999B (zh) 2021-04-09
FI3310340T3 (fi) 2025-12-09
EP4650000A3 (en) 2026-02-25
EP3310340A1 (en) 2018-04-25
JP6916744B2 (ja) 2021-08-11
EP3310340B1 (en) 2025-11-05
CA2987701C (en) 2022-01-25
KR20180019680A (ko) 2018-02-26
US11213531B2 (en) 2022-01-04
US10603327B2 (en) 2020-03-31
DK3310340T3 (da) 2025-12-15
AU2016284935A1 (en) 2017-12-14
US11883415B2 (en) 2024-01-30
HRP20251498T1 (hr) 2026-03-13
WO2016207778A1 (en) 2016-12-29
JP7196247B2 (ja) 2022-12-26

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