DK3310340T3 - Formulering med høj koncentration - Google Patents
Formulering med høj koncentrationInfo
- Publication number
- DK3310340T3 DK3310340T3 DK16733703.9T DK16733703T DK3310340T3 DK 3310340 T3 DK3310340 T3 DK 3310340T3 DK 16733703 T DK16733703 T DK 16733703T DK 3310340 T3 DK3310340 T3 DK 3310340T3
- Authority
- DK
- Denmark
- Prior art keywords
- high concentration
- concentration formulation
- formulation
- concentration
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/28—Antiandrogens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dispersion Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562182988P | 2015-06-22 | 2015-06-22 | |
| EP15173860.6A EP3108879A1 (en) | 2015-06-25 | 2015-06-25 | High concentration formulation |
| PCT/IB2016/053662 WO2016207778A1 (en) | 2015-06-22 | 2016-06-20 | High concentration formulation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3310340T3 true DK3310340T3 (da) | 2025-12-15 |
Family
ID=53491322
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK16733703.9T DK3310340T3 (da) | 2015-06-22 | 2016-06-20 | Formulering med høj koncentration |
Country Status (14)
| Country | Link |
|---|---|
| US (6) | US10603327B2 (da) |
| EP (3) | EP3108879A1 (da) |
| JP (4) | JP6916744B2 (da) |
| KR (1) | KR102636936B1 (da) |
| CN (1) | CN107979999B (da) |
| AU (1) | AU2016284935B2 (da) |
| BR (1) | BR112017027721A2 (da) |
| CA (1) | CA2987701C (da) |
| DK (1) | DK3310340T3 (da) |
| FI (1) | FI3310340T3 (da) |
| MX (1) | MX391040B (da) |
| RU (1) | RU2731564C2 (da) |
| WO (1) | WO2016207778A1 (da) |
| ZA (1) | ZA201708173B (da) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITMI20071616A1 (it) | 2007-08-03 | 2009-02-04 | Cosmo Spa | Processo enzimatico per l'ottenimento di 17-alfa monoesteri del cortexolone e/o suoi 9,11-deidroderivati. |
| EP3108879A1 (en) | 2015-06-25 | 2016-12-28 | Cassiopea S.p.A. | High concentration formulation |
| CN115068423A (zh) * | 2021-03-12 | 2022-09-20 | 浙江万晟药业有限公司 | 一种克拉司酮泡沫剂及其制备方法 |
| CN113425845B (zh) * | 2021-08-10 | 2022-12-02 | 成都倍特药业股份有限公司 | 一种预防和/或治疗脱发症的传递体制剂及其制备方法和用途 |
| WO2024211282A1 (en) * | 2023-04-07 | 2024-10-10 | Amplifica Holdings Group, Inc. | Compositions and methods for treatment of androgenetic alopecia |
| TW202444338A (zh) | 2023-04-07 | 2024-11-16 | 義大利商卡斯歐皮亞股份公司 | 克拉司酮與米諾地爾之組合療法 |
| WO2025068281A1 (en) | 2023-09-26 | 2025-04-03 | Cassiopea S.P.A. | CORTEXOLONE-17α-PROPIONATE FOR TREATING ACNEIFORM ERUPTIONS |
| EP4529925A1 (en) | 2023-09-26 | 2025-04-02 | Cassiopea S.p.A. | Cortexolone-17-alpha- propionate for treating acneiform eruptions |
| WO2025094021A1 (en) * | 2023-10-31 | 2025-05-08 | Lupin Limited | Stable topical cream formulation of clascoterone |
| WO2025125508A1 (en) | 2023-12-14 | 2025-06-19 | Cassiopea S.P.A. | Cortexolone-17αlpha-propionate combinations for treating acne |
| US20250213594A1 (en) * | 2023-12-27 | 2025-07-03 | Inventage Lab Inc. | Novel long-acting injectable composition for preventing or treating androgenetic alopecia containing finasteride |
| WO2025172818A1 (en) | 2024-02-14 | 2025-08-21 | Cassiopea S.P.A. | Pyrilutamide combination therapy |
Family Cites Families (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB791771A (en) | 1954-07-29 | 1958-03-12 | Merck & Co Inc | Steroid compounds |
| US2985650A (en) | 1958-05-28 | 1961-05-23 | Syntex Sa | 6alpha-ammonio-derivatives of 11-keto cortical hormones |
| DE1195748B (de) | 1961-06-24 | 1965-07-01 | Vismara Francesco Spa | Verfahren zur Herstellung von 1'-substituierten 17alpha, 21-(1'-Alkoxy)-methylendioxysterioden |
| NL6605515A (da) | 1966-04-25 | 1967-10-26 | ||
| NL6605514A (da) | 1966-04-25 | 1967-10-26 | ||
| US3780177A (en) | 1967-06-16 | 1973-12-18 | Warner Lambert Co | 17-butyrate,21-ester derivatives of 6alpha,9alpha-difluoroprednisolone,compositions and use |
| US3733318A (en) | 1972-03-23 | 1973-05-15 | Syntex Corp | 21-orthoesters of cortical steroids and methods of preparing same |
| JPS5910799B2 (ja) | 1975-07-15 | 1984-03-12 | 大正製薬株式会社 | プレグナン系ステロイド １７−エステル類の製法 |
| DE3243482A1 (de) | 1982-11-22 | 1984-05-24 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue 6(alpha)-methylkortikoide, ihre herstellung und verwendung |
| DE3402330A1 (de) | 1984-01-20 | 1985-07-25 | Schering AG, 1000 Berlin und 4709 Bergkamen | 1(alpha),2(alpha)-methylen-6-methylen- und 6(alpha)-methyl-pregnene, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate |
| US4920216A (en) | 1987-05-28 | 1990-04-24 | The Trustees Of Columbia In The City Of New York | Selective chlorination of steroids and other substrates directed by covalently linked pyridine derivatives acting as templates |
| US5264428A (en) | 1990-02-16 | 1993-11-23 | Kanoldt Arzneimittel Gmbh | Use of stigmasta-4-en-3-one in the treatment of androgen dependent diseases |
| DE19653730C2 (de) | 1996-12-11 | 1999-06-24 | Schering Ag | Immobilisierte Proteine aus Rohextrakt und deren Verwendung zur Umsetzung von Estern |
| DE69829279T2 (de) | 1997-06-25 | 2006-03-30 | Teijin Ltd. | Vitamin-d3-derivate und aus diesen hergestellte heilmittel gegen entzündliche erkrankungen der atemwege |
| SK14402003A3 (sk) | 2001-05-22 | 2004-06-08 | Pfizer Products Inc. | Kryštalické formy azitromycínu |
| ITMI20011762A1 (it) | 2001-08-10 | 2003-02-10 | Cosmo Spa | Esteri di 17alfa,21-diidrossipregnene, loro uso come agenti anti-androgenetici e procedimenti per la loro preparazione |
| WO2004060347A2 (en) | 2002-09-03 | 2004-07-22 | Transform Pharmaceuticals, Inc. | Pharmaceutical propylene glycol solvate compositions |
| JPWO2003080042A1 (ja) | 2002-03-27 | 2005-07-21 | 塩野義製薬株式会社 | 軟骨細胞外基質分解阻害剤 |
| JP2005539016A (ja) | 2002-08-02 | 2005-12-22 | シエーリング アクチエンゲゼルシャフト | 女性用受胎調節及びホルモン置換療法のための高められた抗ゴナドトロピン活性を有するプロゲステロン受容体モジュレーター |
| DE10236405A1 (de) | 2002-08-02 | 2004-02-19 | Schering Ag | Progesteronrezeptormodulatoren mit erhöhter antigonadotroper Aktivität für die weibliche Fertilitätskontrolle und Hormonersatztherapie |
| US20040138187A1 (en) | 2002-08-28 | 2004-07-15 | Reading Christopher L. | Therapeutic treatment methods |
| WO2004103955A1 (en) | 2003-03-05 | 2004-12-02 | Merck Frosst Company | Nitric oxide releasing prodrugs of diaryl-2-(5h)-furanones as cyclooxygenase-2 inhibitors |
| US20050008704A1 (en) | 2003-07-11 | 2005-01-13 | Ray Anup Kumar | Pharmaceutical composition for solubility enhancement of hydrophobic drugs |
| JP3997255B2 (ja) | 2004-02-13 | 2007-10-24 | ワーナー−ランバート カンパニー リミテッド ライアビリティー カンパニー | アンドロゲンレセプターモジュレーター |
| AU2005232511B2 (en) | 2004-04-14 | 2008-07-03 | Eun-Joo Lee | Pharmaceutical composition for treating hair loss and benign prostatic hyperplasia |
| JP2008189549A (ja) | 2005-05-12 | 2008-08-21 | Astellas Pharma Inc | カルボン酸誘導体またはその塩 |
| PE20070343A1 (es) | 2005-07-29 | 2007-05-12 | Medivir Ab | Inhibidores macrociclicos del virus de la hepatitis c |
| ITMI20051695A1 (it) | 2005-09-14 | 2007-03-15 | Cosmo Spa | Uso di 17a-esteri c3-c10 del 9,11-deidrocortexolone cme agenti anti-gonadotropinici |
| AU2014233572B2 (en) * | 2007-08-03 | 2016-03-03 | Cassiopea S.P.A. | Enzymatic process for obtaining 17 alpha-monoesters of cortexolone and/or its 9,11-dehydroderivatives |
| ITMI20071616A1 (it) | 2007-08-03 | 2009-02-04 | Cosmo Spa | Processo enzimatico per l'ottenimento di 17-alfa monoesteri del cortexolone e/o suoi 9,11-deidroderivati. |
| CA2772579C (en) * | 2009-09-10 | 2015-12-08 | Youzhi Tong | Thioimidazolidinone androgen receptor antagonists and uses thereof |
| JP2014500275A (ja) | 2010-12-06 | 2014-01-09 | フォリカ，インコーポレイテッド | 禿頭症を治療するため、および毛髪の成長を促進するための方法 |
| HK1207961A1 (zh) * | 2011-11-25 | 2016-02-19 | 阿德里安娜‧贾内尔‧杰克逊 | 用於增加毛髮生長和/或預防毛髮損失的油組合物和方法 |
| US9433268B2 (en) | 2013-03-12 | 2016-09-06 | Mark J. S. Ma | Umbrella having a pivot joint to provide additional degrees of freedom of orientation of its canopy |
| CA2900285A1 (en) * | 2013-03-14 | 2014-10-02 | Allergan, Inc. | Topical compositions comprising bimatoprost and methods for stimulating hair growth therewith |
| ITMI20132157A1 (it) | 2013-12-20 | 2015-06-21 | Cosmo Dermatos Srl | Cortexolone 17alfa-propionate for use in the treatment of skin wounds and/or atrophic skin disorders . cortexolone 17alfa-propionato per uso nel trattamento delle ferite della pelle e/o disordini atrofici della pelle. |
| EP3108879A1 (en) | 2015-06-25 | 2016-12-28 | Cassiopea S.p.A. | High concentration formulation |
-
2015
- 2015-06-25 EP EP15173860.6A patent/EP3108879A1/en not_active Ceased
-
2016
- 2016-06-20 WO PCT/IB2016/053662 patent/WO2016207778A1/en not_active Ceased
- 2016-06-20 US US15/738,151 patent/US10603327B2/en active Active
- 2016-06-20 BR BR112017027721A patent/BR112017027721A2/pt not_active Application Discontinuation
- 2016-06-20 EP EP25205438.2A patent/EP4650000A2/en active Pending
- 2016-06-20 EP EP16733703.9A patent/EP3310340B1/en active Active
- 2016-06-20 KR KR1020187001619A patent/KR102636936B1/ko active Active
- 2016-06-20 AU AU2016284935A patent/AU2016284935B2/en active Active
- 2016-06-20 CA CA2987701A patent/CA2987701C/en active Active
- 2016-06-20 DK DK16733703.9T patent/DK3310340T3/da active
- 2016-06-20 CN CN201680036665.5A patent/CN107979999B/zh active Active
- 2016-06-20 FI FIEP16733703.9T patent/FI3310340T3/fi active
- 2016-06-20 RU RU2018101870A patent/RU2731564C2/ru active
- 2016-06-20 JP JP2017566315A patent/JP6916744B2/ja active Active
- 2016-06-20 MX MX2017017119A patent/MX391040B/es unknown
-
2017
- 2017-11-30 ZA ZA2017/08173A patent/ZA201708173B/en unknown
-
2019
- 2019-05-01 US US16/400,262 patent/US20190282589A1/en not_active Abandoned
- 2019-08-01 US US16/529,214 patent/US10980819B2/en active Active
-
2020
- 2020-03-24 US US16/828,727 patent/US11213531B2/en active Active
-
2021
- 2021-07-16 JP JP2021117906A patent/JP7196247B2/ja active Active
- 2021-11-23 US US17/456,218 patent/US11883415B2/en active Active
-
2022
- 2022-12-14 JP JP2022199305A patent/JP7458464B2/ja active Active
-
2023
- 2023-12-14 US US18/539,531 patent/US20240189324A1/en active Pending
-
2024
- 2024-03-18 JP JP2024042141A patent/JP2024069534A/ja active Pending
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