PL3297987T3 - Nowe pochodne azetydyny użyteczne jako modulatory korowego neuroprzekaźnictwa katecholaminergicznego - Google Patents

Nowe pochodne azetydyny użyteczne jako modulatory korowego neuroprzekaźnictwa katecholaminergicznego

Info

Publication number
PL3297987T3
PL3297987T3 PL16724046T PL16724046T PL3297987T3 PL 3297987 T3 PL3297987 T3 PL 3297987T3 PL 16724046 T PL16724046 T PL 16724046T PL 16724046 T PL16724046 T PL 16724046T PL 3297987 T3 PL3297987 T3 PL 3297987T3
Authority
PL
Poland
Prior art keywords
cathecolaminergic
neurotransmission
cortical
modulators
derivatives useful
Prior art date
Application number
PL16724046T
Other languages
English (en)
Inventor
Fredrik Pettersson
Clas Sonesson
Original Assignee
Integrative Res Laboratories Sweden Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Integrative Res Laboratories Sweden Ab filed Critical Integrative Res Laboratories Sweden Ab
Publication of PL3297987T3 publication Critical patent/PL3297987T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/04Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL16724046T 2015-05-20 2016-05-20 Nowe pochodne azetydyny użyteczne jako modulatory korowego neuroprzekaźnictwa katecholaminergicznego PL3297987T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP15168373 2015-05-20
SE1650485 2016-04-11
EP16724046.4A EP3297987B1 (en) 2015-05-20 2016-05-20 Novel azetidine derivatives useful as modulators of cortical cathecolaminergic neurotransmission
PCT/EP2016/061479 WO2016185032A1 (en) 2015-05-20 2016-05-20 Novel azetidine derivatives useful as modulators of cortical cathecolaminergic neurotransmission

Publications (1)

Publication Number Publication Date
PL3297987T3 true PL3297987T3 (pl) 2019-10-31

Family

ID=56026881

Family Applications (1)

Application Number Title Priority Date Filing Date
PL16724046T PL3297987T3 (pl) 2015-05-20 2016-05-20 Nowe pochodne azetydyny użyteczne jako modulatory korowego neuroprzekaźnictwa katecholaminergicznego

Country Status (18)

Country Link
US (2) US10087142B2 (pl)
EP (1) EP3297987B1 (pl)
JP (1) JP6679621B2 (pl)
KR (1) KR102595892B1 (pl)
CN (1) CN107646031B (pl)
AU (1) AU2016263510B2 (pl)
CA (1) CA2985710C (pl)
DK (1) DK3297987T3 (pl)
ES (1) ES2730890T3 (pl)
HK (1) HK1245251B (pl)
IL (1) IL255618B (pl)
MX (1) MX365283B (pl)
NZ (1) NZ737451A (pl)
PL (1) PL3297987T3 (pl)
PT (1) PT3297987T (pl)
RU (1) RU2716814C2 (pl)
WO (1) WO2016185032A1 (pl)
ZA (1) ZA201707936B (pl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ737451A (en) * 2015-05-20 2022-01-28 Integrative Res Laboratories Sweden Ab Novel azetidine derivatives useful as modulators of cortical catecholaminergic neurotransmission
ES2962865T3 (es) 2016-11-18 2024-03-21 Integrative Res Laboratories Sweden Ab Nuevos derivados de azetidina útiles como moduladores de la neurotransmisión catecolaminérgica cortical

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU1512969A1 (ru) * 1988-02-01 1989-10-07 Институт нефтехимического синтеза им.А.В.Топчиева Способ получени N-алкилазетидинов
FR2805818B1 (fr) * 2000-03-03 2002-04-26 Aventis Pharma Sa Derives d'azetidine, leur preparation et les compositions pharmaceutiques les contenant
EP1638939A2 (en) 2003-06-24 2006-03-29 Neurosearch A/S Aza-ring derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
KR20100038295A (ko) 2007-06-05 2010-04-14 엔에스아베 필리알 아프 뉴로서치 스웨덴 아베 스베리게 피질 카테콜아민성 신경 전달의 조정자로서의 이치환된 페닐피롤리딘
CN102224135A (zh) * 2008-11-24 2011-10-19 Nsab神经研究瑞典公司分公司 用作皮质儿茶酚胺能神经传递调节剂的新3-苯基-氮杂环丁烷衍生物
JP5716202B2 (ja) * 2008-11-24 2015-05-13 インテグレイティブ・リサーチ・ラボラトリーズ・スウェーデン・アーベー 皮質のカテコールアミン作動性神経伝達のモジュレーターとしての3−フェニル−3−メトキシピロリジン誘導体
EP2367786B1 (en) * 2008-11-24 2013-01-09 NSAB, Filial af NeuroSearch Sweden AB, Sverige Novel 1 -alkyl- 3 -hydroxy- 3 -phenylazetidine derivatives useful as modulators of cortical catecholaminergic neurotransmission
KR101273566B1 (ko) * 2011-09-05 2013-06-11 한국과학기술연구원 신규한 아제티딘 유도체 및 이를 함유하는 항우울제 조성물
NZ737451A (en) * 2015-05-20 2022-01-28 Integrative Res Laboratories Sweden Ab Novel azetidine derivatives useful as modulators of cortical catecholaminergic neurotransmission

Also Published As

Publication number Publication date
AU2016263510A1 (en) 2017-12-07
ZA201707936B (en) 2020-01-29
MX2017014577A (es) 2018-06-11
RU2017140419A (ru) 2019-06-20
CA2985710C (en) 2023-07-25
US10287247B2 (en) 2019-05-14
JP6679621B2 (ja) 2020-04-15
US20190031606A1 (en) 2019-01-31
CN107646031B (zh) 2020-11-17
NZ737451A (en) 2022-01-28
AU2016263510B2 (en) 2020-03-12
EP3297987B1 (en) 2019-05-15
DK3297987T3 (da) 2019-06-17
CA2985710A1 (en) 2016-11-24
JP2018520100A (ja) 2018-07-26
ES2730890T3 (es) 2019-11-13
RU2716814C2 (ru) 2020-03-17
CN107646031A (zh) 2018-01-30
IL255618B (en) 2020-02-27
HK1245251B (zh) 2020-04-24
MX365283B (es) 2019-05-29
EP3297987A1 (en) 2018-03-28
IL255618A (en) 2018-01-31
US20180141903A1 (en) 2018-05-24
RU2017140419A3 (pl) 2019-07-26
WO2016185032A1 (en) 2016-11-24
US10087142B2 (en) 2018-10-02
PT3297987T (pt) 2019-06-19
KR102595892B1 (ko) 2023-10-31
KR20180004742A (ko) 2018-01-12

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