PL3207124T3 - Sposoby i kompozycje do wytwarzania lub utrzymywania komórek pluripotencjalnych - Google Patents
Sposoby i kompozycje do wytwarzania lub utrzymywania komórek pluripotencjalnychInfo
- Publication number
- PL3207124T3 PL3207124T3 PL15787382T PL15787382T PL3207124T3 PL 3207124 T3 PL3207124 T3 PL 3207124T3 PL 15787382 T PL15787382 T PL 15787382T PL 15787382 T PL15787382 T PL 15787382T PL 3207124 T3 PL3207124 T3 PL 3207124T3
- Authority
- PL
- Poland
- Prior art keywords
- compositions
- generating
- methods
- pluripotent cells
- maintaining pluripotent
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/32—Amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/38—Vitamins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/44—Thiols, e.g. mercaptoethanol
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/60—Buffer, e.g. pH regulation, osmotic pressure
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/235—Leukemia inhibitory factor [LIF]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/70—Enzymes
- C12N2501/72—Transferases [EC 2.]
- C12N2501/727—Kinases (EC 2.7.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2509/00—Methods for the dissociation of cells, e.g. specific use of enzymes
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Developmental Biology & Embryology (AREA)
- Microbiology (AREA)
- Transplantation (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462064384P | 2014-10-15 | 2014-10-15 | |
| PCT/US2015/055776 WO2016061374A1 (en) | 2014-10-15 | 2015-10-15 | Methods and compositions for generating or maintaining pluripotent cells |
| EP15787382.9A EP3207124B1 (en) | 2014-10-15 | 2015-10-15 | Methods and compositions for generating or maintaining pluripotent cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3207124T3 true PL3207124T3 (pl) | 2019-11-29 |
Family
ID=54361190
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL15787382T PL3207124T3 (pl) | 2014-10-15 | 2015-10-15 | Sposoby i kompozycje do wytwarzania lub utrzymywania komórek pluripotencjalnych |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US10428310B2 (pl) |
| EP (2) | EP3207124B1 (pl) |
| JP (1) | JP2017536811A (pl) |
| KR (1) | KR20170070136A (pl) |
| CN (1) | CN107002042A (pl) |
| AU (1) | AU2015332451A1 (pl) |
| BR (1) | BR112017007770A2 (pl) |
| CA (1) | CA2963315A1 (pl) |
| CY (1) | CY1122179T1 (pl) |
| DK (1) | DK3207124T3 (pl) |
| ES (1) | ES2741387T3 (pl) |
| IL (1) | IL251576A0 (pl) |
| MX (1) | MX2017004890A (pl) |
| PL (1) | PL3207124T3 (pl) |
| PT (1) | PT3207124T (pl) |
| RU (1) | RU2706965C2 (pl) |
| SG (2) | SG11201702309RA (pl) |
| WO (1) | WO2016061374A1 (pl) |
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| WO2011156723A1 (en) | 2010-06-11 | 2011-12-15 | Regeneron Pharmaceuticals, Inc. | Production of fertile xy female animals from xy es cells |
| US10323236B2 (en) | 2011-07-22 | 2019-06-18 | President And Fellows Of Harvard College | Evaluation and improvement of nuclease cleavage specificity |
| EP2746386A1 (en) * | 2012-12-21 | 2014-06-25 | Lonza Cologne GmbH | Materials and methods for cell culture |
| HRP20181648T1 (hr) | 2013-04-16 | 2019-01-25 | Regeneron Pharmaceuticals, Inc. | Ciljana modifikacija genoma štakora |
| US10738323B2 (en) | 2013-07-12 | 2020-08-11 | Cedars-Sinai Medical Center | Generation of induced pluripotent stem cells from normal human mammary epithelial cells |
| US9163284B2 (en) | 2013-08-09 | 2015-10-20 | President And Fellows Of Harvard College | Methods for identifying a target site of a Cas9 nuclease |
| US9359599B2 (en) | 2013-08-22 | 2016-06-07 | President And Fellows Of Harvard College | Engineered transcription activator-like effector (TALE) domains and uses thereof |
| US9340799B2 (en) | 2013-09-06 | 2016-05-17 | President And Fellows Of Harvard College | MRNA-sensing switchable gRNAs |
| US9526784B2 (en) | 2013-09-06 | 2016-12-27 | President And Fellows Of Harvard College | Delivery system for functional nucleases |
| US9322037B2 (en) | 2013-09-06 | 2016-04-26 | President And Fellows Of Harvard College | Cas9-FokI fusion proteins and uses thereof |
| MX388127B (es) | 2013-12-11 | 2025-03-19 | Regeneron Pharma | Metodos y composiciones para la modificacion dirigida de un genoma. |
| US20150165054A1 (en) | 2013-12-12 | 2015-06-18 | President And Fellows Of Harvard College | Methods for correcting caspase-9 point mutations |
| CA2950173C (en) | 2014-06-06 | 2023-10-10 | Regeneron Pharmaceuticals, Inc. | Methods and compositions for modifying a targeted locus |
| KR102386101B1 (ko) | 2014-06-26 | 2022-04-14 | 리제너론 파마슈티칼스 인코포레이티드 | 표적화된 유전자 변형을 위한 방법 및 그 조성물, 및 사용 방법 |
| US10077453B2 (en) | 2014-07-30 | 2018-09-18 | President And Fellows Of Harvard College | CAS9 proteins including ligand-dependent inteins |
| PL3207124T3 (pl) | 2014-10-15 | 2019-11-29 | Regeneron Pharma | Sposoby i kompozycje do wytwarzania lub utrzymywania komórek pluripotencjalnych |
| ES2731437T3 (es) | 2014-11-21 | 2019-11-15 | Regeneron Pharma | Métodos y composiciones para la modificación genética dirigida mediante el uso de pares de ARN guías |
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| CN107429261A (zh) * | 2014-12-15 | 2017-12-01 | 应用干细胞有限公司 | 在细胞中迅速产生单一或多重报告基因的方法和组合物 |
| CN107208113A (zh) | 2014-12-19 | 2017-09-26 | 瑞泽恩制药公司 | 用于通过单步多重靶向进行靶向遗传修饰的方法和组合物 |
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| US10167457B2 (en) | 2015-10-23 | 2019-01-01 | President And Fellows Of Harvard College | Nucleobase editors and uses thereof |
| EP3452055A4 (en) * | 2016-05-06 | 2019-11-06 | Tod M. Woolf | IMPROVED METHODS FOR GENERIC MODIFICATION WITH AND WITHOUT PROGRAMMABLE NUCLEASES |
| US10221395B2 (en) | 2016-06-16 | 2019-03-05 | Cedars-Sinai Medical Center | Efficient method for reprogramming blood to induced pluripotent stem cells |
| US11572545B2 (en) | 2016-06-16 | 2023-02-07 | Cedars-Sinai Medical Center | Efficient method for reprogramming blood to induced pluripotent stem cells |
| KR20250103795A (ko) | 2016-08-03 | 2025-07-07 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 아데노신 핵염기 편집제 및 그의 용도 |
| EP3497214B1 (en) | 2016-08-09 | 2023-06-28 | President and Fellows of Harvard College | Programmable cas9-recombinase fusion proteins and uses thereof |
| WO2018039438A1 (en) | 2016-08-24 | 2018-03-01 | President And Fellows Of Harvard College | Incorporation of unnatural amino acids into proteins using base editing |
| WO2018057782A1 (en) * | 2016-09-23 | 2018-03-29 | University Of Utah Research Foundation | Methods of preventing stem cell differentiation using a pask inhibitor |
| AU2017342543B2 (en) | 2016-10-14 | 2024-06-27 | President And Fellows Of Harvard College | AAV delivery of nucleobase editors |
| JP2018082639A (ja) * | 2016-11-21 | 2018-05-31 | 学校法人千葉工業大学 | 体細胞から人工多能性幹細胞を製造する方法及び人工多能性幹細胞を未分化のまま培養するための培地 |
| US10745677B2 (en) | 2016-12-23 | 2020-08-18 | President And Fellows Of Harvard College | Editing of CCR5 receptor gene to protect against HIV infection |
| EP3592853A1 (en) | 2017-03-09 | 2020-01-15 | President and Fellows of Harvard College | Suppression of pain by gene editing |
| US12390514B2 (en) | 2017-03-09 | 2025-08-19 | President And Fellows Of Harvard College | Cancer vaccine |
| US11542496B2 (en) | 2017-03-10 | 2023-01-03 | President And Fellows Of Harvard College | Cytosine to guanine base editor |
| BR112019019655A2 (pt) | 2017-03-23 | 2020-04-22 | Harvard College | editores de nucleobase que compreendem proteínas de ligação a dna programáveis por ácido nucleico |
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| US12351837B2 (en) | 2019-01-23 | 2025-07-08 | The Broad Institute, Inc. | Supernegatively charged proteins and uses thereof |
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-
2015
- 2015-10-15 PL PL15787382T patent/PL3207124T3/pl unknown
- 2015-10-15 PT PT15787382T patent/PT3207124T/pt unknown
- 2015-10-15 ES ES15787382T patent/ES2741387T3/es active Active
- 2015-10-15 AU AU2015332451A patent/AU2015332451A1/en not_active Abandoned
- 2015-10-15 SG SG11201702309RA patent/SG11201702309RA/en unknown
- 2015-10-15 EP EP15787382.9A patent/EP3207124B1/en active Active
- 2015-10-15 CN CN201580056328.8A patent/CN107002042A/zh active Pending
- 2015-10-15 MX MX2017004890A patent/MX2017004890A/es unknown
- 2015-10-15 WO PCT/US2015/055776 patent/WO2016061374A1/en not_active Ceased
- 2015-10-15 DK DK15787382.9T patent/DK3207124T3/da active
- 2015-10-15 BR BR112017007770A patent/BR112017007770A2/pt not_active Application Discontinuation
- 2015-10-15 SG SG10201913797YA patent/SG10201913797YA/en unknown
- 2015-10-15 US US14/884,293 patent/US10428310B2/en active Active
- 2015-10-15 EP EP19178485.9A patent/EP3561052A1/en not_active Withdrawn
- 2015-10-15 RU RU2017116678A patent/RU2706965C2/ru active
- 2015-10-15 CA CA2963315A patent/CA2963315A1/en not_active Abandoned
- 2015-10-15 JP JP2017520466A patent/JP2017536811A/ja active Pending
- 2015-10-15 KR KR1020177012730A patent/KR20170070136A/ko not_active Withdrawn
-
2017
- 2017-04-05 IL IL251576A patent/IL251576A0/en unknown
-
2019
- 2019-07-30 CY CY20191100817T patent/CY1122179T1/el unknown
- 2019-08-05 US US16/531,901 patent/US20190382730A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| RU2706965C2 (ru) | 2019-11-21 |
| DK3207124T3 (da) | 2019-08-12 |
| US20160108369A1 (en) | 2016-04-21 |
| SG11201702309RA (en) | 2017-04-27 |
| KR20170070136A (ko) | 2017-06-21 |
| WO2016061374A1 (en) | 2016-04-21 |
| EP3207124A1 (en) | 2017-08-23 |
| CN107002042A (zh) | 2017-08-01 |
| CA2963315A1 (en) | 2016-04-21 |
| RU2017116678A (ru) | 2018-11-22 |
| EP3207124B1 (en) | 2019-06-26 |
| IL251576A0 (en) | 2017-06-29 |
| EP3561052A1 (en) | 2019-10-30 |
| US10428310B2 (en) | 2019-10-01 |
| BR112017007770A2 (pt) | 2018-01-16 |
| SG10201913797YA (en) | 2020-03-30 |
| CY1122179T1 (el) | 2020-11-25 |
| US20190382730A1 (en) | 2019-12-19 |
| MX2017004890A (es) | 2018-02-12 |
| AU2015332451A1 (en) | 2017-04-20 |
| ES2741387T3 (es) | 2020-02-10 |
| PT3207124T (pt) | 2019-08-27 |
| JP2017536811A (ja) | 2017-12-14 |
| RU2017116678A3 (pl) | 2019-05-22 |
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