PL307309A1 - Prodrugs of imidazocarboxylic acids as antagonists of angiotensin ii receptors - Google Patents
Prodrugs of imidazocarboxylic acids as antagonists of angiotensin ii receptorsInfo
- Publication number
- PL307309A1 PL307309A1 PL93307309A PL30730993A PL307309A1 PL 307309 A1 PL307309 A1 PL 307309A1 PL 93307309 A PL93307309 A PL 93307309A PL 30730993 A PL30730993 A PL 30730993A PL 307309 A1 PL307309 A1 PL 307309A1
- Authority
- PL
- Poland
- Prior art keywords
- imidazocarboxylic
- angiotensin
- prodrugs
- antagonists
- receptors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/926,795 US5310929A (en) | 1992-08-06 | 1992-08-06 | Prodrugs of imidazole carboxylic acids as angiotensin II receptor antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL307309A1 true PL307309A1 (en) | 1995-05-15 |
Family
ID=25453732
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL93307309A PL307309A1 (en) | 1992-08-06 | 1993-08-02 | Prodrugs of imidazocarboxylic acids as antagonists of angiotensin ii receptors |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US5310929A (forum.php) |
| EP (1) | EP0654027A1 (forum.php) |
| JP (1) | JP2892838B2 (forum.php) |
| CN (1) | CN1090275A (forum.php) |
| AU (1) | AU688735B2 (forum.php) |
| BR (1) | BR9306911A (forum.php) |
| CA (1) | CA2141692C (forum.php) |
| FI (1) | FI950485L (forum.php) |
| HU (1) | HU9500349D0 (forum.php) |
| IL (1) | IL106553A0 (forum.php) |
| MX (1) | MX9304787A (forum.php) |
| NO (1) | NO950404D0 (forum.php) |
| PL (1) | PL307309A1 (forum.php) |
| SG (1) | SG47108A1 (forum.php) |
| SK (1) | SK13195A3 (forum.php) |
| TW (1) | TW239131B (forum.php) |
| WO (1) | WO1994003435A1 (forum.php) |
| ZA (1) | ZA935693B (forum.php) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5616599A (en) * | 1991-02-21 | 1997-04-01 | Sankyo Company, Limited | Angiotensin II antagosist 1-biphenylmethylimidazole compounds and their therapeutic use |
| CZ283315B6 (cs) * | 1992-12-17 | 1998-02-18 | Sankyo Company Limited | Bifenylové deriváty, způsob výroby a farmaceutické prostředky k léčení hypertense a srdečních onemocnění, které tyto deriváty obsahují |
| ATE266402T1 (de) * | 1994-03-16 | 2004-05-15 | Sankyo Co | Okulares hypotonikum |
| US6221335B1 (en) * | 1994-03-25 | 2001-04-24 | Isotechnika, Inc. | Method of using deuterated calcium channel blockers |
| US5510495A (en) * | 1994-09-19 | 1996-04-23 | The Du Pont Merck Pharmaceutical Company | Process for the isolation and purification of ester functionalized imidazole intermediates by selective hydrolysis |
| EP0782996B1 (en) * | 1994-09-20 | 1999-02-17 | Wakunaga Seiyaku Kabushiki Kaisha | Process for producing n-biphenylmethylthiadiazoline derivative or salt thereof and intermediate for producing the same |
| IT1292437B1 (it) | 1997-06-30 | 1999-02-08 | Zambon Spa | Processo di orto-metallazione utile per la sintesi di 1 - tetrazol- 5-il) benzeni 2-sostituiti |
| IT1295405B1 (it) | 1997-09-30 | 1999-05-12 | Merck Sharp & Dohme Italia S P | Uso di un antagonista recettoriale di angiotensina ii per la preparazione di farmaci per aumentare il tasso di sopravvivenza di |
| DE19820064A1 (de) * | 1998-05-06 | 1999-11-11 | Hoechst Marion Roussel De Gmbh | Substituierte Sulfonylcyanamide, Verfahren zu ihrer Herstellung und ihre Verwendung als Medikament |
| DE19832428A1 (de) * | 1998-07-18 | 2000-01-20 | Hoechst Marion Roussel De Gmbh | Imidazolderivate mit Biphenylsulfonylsubstitution, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE19832429A1 (de) * | 1998-07-18 | 2000-01-20 | Hoechst Marion Roussel De Gmbh | Imidazolderivate mit Biphenylsulfonylsubstitution, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| ES2154191B1 (es) * | 1998-11-24 | 2001-10-16 | Ferrer Int | Nuevos acetales derivados de los 2-alquil-5-halo-3-(2'-(tetrazol-5-il)-bifenil-4-ilmetil)-3h-imidazol-4-carbaldehidos. |
| GR20000100281A (el) * | 2000-08-17 | 2002-05-24 | Ιωαννης Ματσουκας | Ανταγωνιστες του υποδοχεα της αγγεοτενσινης ιι και συνθετικες μεθοδοι για την θεραπεια της υπερτασης και καρδιοαγγειακων ασθενειων |
| CA2449150C (en) | 2001-05-31 | 2011-07-12 | Vicore Pharma Ab | Tricyclic compounds useful as angiotensin ii agonists |
| ATE398121T1 (de) | 2003-01-16 | 2008-07-15 | Teva Pharma | Neue synthese von irbesartan |
| JP4779067B2 (ja) | 2004-01-20 | 2011-09-21 | 愛知県 | ＨＬＡ−Ａ２４０２拘束性Ｅｐ−ＣＡＭ特異的ＣＴＬが認識するエピトープ・ペプチド及びその用途 |
| US7157584B2 (en) * | 2004-02-25 | 2007-01-02 | Takeda Pharmaceutical Company Limited | Benzimidazole derivative and use thereof |
| US20070054948A1 (en) * | 2004-09-02 | 2007-03-08 | Lilach Hedvati | Purification of olmesartan medoxomil |
| WO2006029057A1 (en) * | 2004-09-02 | 2006-03-16 | Teva Pharmaceutical Industries, Ltd. | Purification of olmesartan medoxomil |
| CN101160126A (zh) * | 2005-04-20 | 2008-04-09 | 默克公司 | 血管紧张肽ⅱ受体拮抗剂 |
| ES2302671T1 (es) * | 2006-08-29 | 2008-08-01 | Teva Pharmaceutical Industries Ltd. | Procedimientos para la sintesis de 5-fenil-1-tritil-1h-tetrazol. |
| US8076492B2 (en) * | 2006-10-09 | 2011-12-13 | Cipla Limited | Process for preparing trityl olmesartan medoxomil and olmesartan medoxomil |
| WO2008067687A1 (fr) * | 2006-12-06 | 2008-06-12 | Shanghai Allist Pharmaceutical., Inc. | Sels de dérivés d'acide imidazol-5-carboxylique, procédés de préparation et utilisation |
| ES2768295T3 (es) | 2010-01-07 | 2020-06-22 | Alkermes Pharma Ireland Ltd | Profármacos de compuestos heteroaromáticos |
| EP2455388A1 (en) | 2010-11-23 | 2012-05-23 | LanthioPep B.V. | Novel angiotensin type 2 (AT2) receptor agonists and uses thereof. |
| CN109320501B (zh) * | 2013-11-01 | 2021-06-01 | 深圳信立泰药业股份有限公司 | 阿利沙坦酯无定形及其制备方法及含所述无定形的药物组合物 |
| JP2022542437A (ja) | 2019-08-02 | 2022-10-03 | ランティオペプ ベスローテン ヴェンノーツハップ | 癌の処置に用いるアンジオテンシン２型（ａｔ２）受容体アゴニスト |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5138069A (en) * | 1986-07-11 | 1992-08-11 | E. I. Du Pont De Nemours And Company | Angiotensin II receptor blocking imidazoles |
| CA1338238C (en) * | 1988-01-07 | 1996-04-09 | David John Carini | Angiotensin ii receptor blocking imidazoles and combinations thereof with diuretics and nsaids |
| SG52709A1 (en) * | 1989-06-30 | 1998-09-28 | Du Pont | Substituted imidazoles |
| FI916130A7 (fi) * | 1989-06-30 | 1991-12-27 | Du Pont | Aryylisubstituoituja imidatsoleja |
| GB8927277D0 (en) * | 1989-12-01 | 1990-01-31 | Glaxo Group Ltd | Chemical compounds |
| US5196444A (en) * | 1990-04-27 | 1993-03-23 | Takeda Chemical Industries, Ltd. | 1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylate and compositions and methods of pharmaceutical use thereof |
| US5137902A (en) * | 1990-07-13 | 1992-08-11 | E. I. Du Pont De Nemours And Company | 4-alkylimidazole derivatives and anti-hypertensive use thereof |
| ATE199548T1 (de) * | 1992-06-02 | 2001-03-15 | Sankyo Co | 4-carboxyimidazolderivate als angiotensin-ii- antagonisten und ihre therapeutische verwendung |
-
1992
- 1992-08-06 US US07/926,795 patent/US5310929A/en not_active Expired - Lifetime
-
1993
- 1993-08-02 HU HU9500349A patent/HU9500349D0/hu unknown
- 1993-08-02 AU AU47903/93A patent/AU688735B2/en not_active Ceased
- 1993-08-02 SK SK131-95A patent/SK13195A3/sk unknown
- 1993-08-02 CA CA002141692A patent/CA2141692C/en not_active Expired - Lifetime
- 1993-08-02 PL PL93307309A patent/PL307309A1/xx unknown
- 1993-08-02 BR BR9306911A patent/BR9306911A/pt not_active Application Discontinuation
- 1993-08-02 WO PCT/US1993/007103 patent/WO1994003435A1/en not_active Application Discontinuation
- 1993-08-02 SG SG1996008109A patent/SG47108A1/en unknown
- 1993-08-02 FI FI950485A patent/FI950485L/fi not_active Application Discontinuation
- 1993-08-02 JP JP6505415A patent/JP2892838B2/ja not_active Expired - Lifetime
- 1993-08-02 IL IL106553A patent/IL106553A0/xx unknown
- 1993-08-02 EP EP93918463A patent/EP0654027A1/en not_active Withdrawn
- 1993-08-05 ZA ZA935693A patent/ZA935693B/xx unknown
- 1993-08-06 CN CN93117634A patent/CN1090275A/zh active Pending
- 1993-08-06 TW TW082106302A patent/TW239131B/zh active
- 1993-08-06 MX MX9304787A patent/MX9304787A/es unknown
-
1995
- 1995-02-03 NO NO950404A patent/NO950404D0/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO950404D0 (no) | 1995-02-03 |
| CA2141692A1 (en) | 1994-02-17 |
| FI950485A0 (fi) | 1995-02-03 |
| IL106553A0 (en) | 1993-12-08 |
| FI950485A7 (fi) | 1995-02-03 |
| ZA935693B (en) | 1995-02-06 |
| TW239131B (forum.php) | 1995-01-21 |
| JPH08500103A (ja) | 1996-01-09 |
| CA2141692C (en) | 2006-05-30 |
| WO1994003435A1 (en) | 1994-02-17 |
| HU9500349D0 (en) | 1995-03-28 |
| FI950485L (fi) | 1995-02-03 |
| SK13195A3 (en) | 1995-07-11 |
| AU4790393A (en) | 1994-03-03 |
| EP0654027A1 (en) | 1995-05-24 |
| JP2892838B2 (ja) | 1999-05-17 |
| BR9306911A (pt) | 1998-12-08 |
| AU688735B2 (en) | 1998-03-19 |
| MX9304787A (es) | 1995-01-31 |
| CN1090275A (zh) | 1994-08-03 |
| SG47108A1 (en) | 1998-03-20 |
| US5310929A (en) | 1994-05-10 |
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