PL3067349T3 - Pochodna karboksymetylopiperydyny - Google Patents
Pochodna karboksymetylopiperydynyInfo
- Publication number
- PL3067349T3 PL3067349T3 PL14860761T PL14860761T PL3067349T3 PL 3067349 T3 PL3067349 T3 PL 3067349T3 PL 14860761 T PL14860761 T PL 14860761T PL 14860761 T PL14860761 T PL 14860761T PL 3067349 T3 PL3067349 T3 PL 3067349T3
- Authority
- PL
- Poland
- Prior art keywords
- piperidine derivative
- carboxymethyl piperidine
- carboxymethyl
- derivative
- piperidine
- Prior art date
Links
- VRDBIJCCXDEZJN-UHFFFAOYSA-N 2-piperidin-1-ylacetic acid Chemical class OC(=O)CN1CCCCC1 VRDBIJCCXDEZJN-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2013231773 | 2013-11-08 | ||
PCT/JP2014/079384 WO2015068744A1 (ja) | 2013-11-08 | 2014-11-06 | カルボキシメチルピペリジン誘導体 |
EP14860761.7A EP3067349B1 (en) | 2013-11-08 | 2014-11-06 | Carboxymethyl piperidine derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
PL3067349T3 true PL3067349T3 (pl) | 2018-06-29 |
Family
ID=53041521
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL14860761T PL3067349T3 (pl) | 2013-11-08 | 2014-11-06 | Pochodna karboksymetylopiperydyny |
Country Status (15)
Country | Link |
---|---|
US (1) | US10100030B2 (pl) |
EP (1) | EP3067349B1 (pl) |
JP (1) | JP5806420B1 (pl) |
KR (1) | KR20160078997A (pl) |
CN (1) | CN105745198B (pl) |
AU (1) | AU2014347644B2 (pl) |
BR (1) | BR112016009811A2 (pl) |
CA (1) | CA2930008A1 (pl) |
ES (1) | ES2671418T3 (pl) |
IL (1) | IL245286B (pl) |
MX (1) | MX368070B (pl) |
PL (1) | PL3067349T3 (pl) |
RU (1) | RU2673084C2 (pl) |
TW (1) | TWI657082B (pl) |
WO (1) | WO2015068744A1 (pl) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI649307B (zh) | 2014-05-07 | 2019-02-01 | 日商橘生藥品工業股份有限公司 | Cyclohexylpyridine derivative |
JP6609253B2 (ja) * | 2014-08-06 | 2019-11-20 | キッセイ薬品工業株式会社 | シアノチオフェン誘導体 |
US10399949B2 (en) | 2015-12-07 | 2019-09-03 | Kissei Pharmaceutical Co., Ltd. | NK1 receptor antagonist |
TWI745383B (zh) | 2016-06-21 | 2021-11-11 | 日商Dic股份有限公司 | 經醇改質之聚醯胺醯亞胺樹脂及其製造方法 |
KR20220101090A (ko) | 2019-11-15 | 2022-07-19 | 칸디 테라퓨틱스 리미티드 | Nt-814의 핵심 중간체인 6-클로로-4-(4-플루오로-2-메틸페닐)피리딘-3-아민의 새로운 화학적 제조 방법 |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT1394150E (pt) * | 1999-02-24 | 2011-02-17 | Hoffmann La Roche | Derivados de 4-fenilpiridina e a sua utilização como antagonistas dos receptores de nc-1 |
RU2236402C2 (ru) | 1999-02-24 | 2004-09-20 | Ф.Хоффманн-Ля Рош Аг | Производные 3-фенилпиридина и фармацевтическая композиция на их основе |
EP1103545B1 (en) | 1999-11-29 | 2003-11-05 | F. Hoffmann-La Roche Ag | 2-(3,5-Bis-trifluoromethyl-phenyl)-N-methyl-N-(6-morpholin-4-yl-4-o-tolyl-pyridin-3-yl)-isobutyramide |
SI1303490T1 (sl) | 2000-07-14 | 2008-10-31 | Hoffmann La Roche | N-oksidi kot predzdravila NK 1 receptorskega antagonista 4-fenil-piridin derivatov |
TWI287003B (en) | 2000-07-24 | 2007-09-21 | Hoffmann La Roche | 4-phenyl-pyridine derivatives |
TWI259180B (en) | 2000-08-08 | 2006-08-01 | Hoffmann La Roche | 4-Phenyl-pyridine derivatives |
JP4146730B2 (ja) | 2001-04-23 | 2008-09-10 | エフ.ホフマン−ラ ロシュ アーゲー | 良性前立腺肥大に対するnk−1受容体拮抗薬の使用 |
US20030083345A1 (en) | 2001-07-10 | 2003-05-01 | Torsten Hoffmann | Method of treatment and/or prevention of brain, spinal or nerve injury |
US6849624B2 (en) | 2001-07-31 | 2005-02-01 | Hoffmann-La Roche Inc. | Aromatic and heteroaromatic substituted amides |
EP1643998B1 (en) | 2003-07-03 | 2007-08-29 | F. Hoffmann-La Roche Ag | Dual nk1/nk3 antagonists for treating schizophrenia |
US20060030600A1 (en) | 2004-08-06 | 2006-02-09 | Patrick Schnider | Dual NK1/NK3 receptor antagonists for the treatment of schizophrenia |
ATE425144T1 (de) | 2005-03-23 | 2009-03-15 | Hoffmann La Roche | Metaboliten für nk-i-antagonisten zur emesis |
KR101292348B1 (ko) | 2005-09-09 | 2013-09-09 | 네르 쎄라퓨틱스 리미티드 | 피리딘 유도체 및 그의 정신병적 장애의 치료에 있어서의용도 |
BRPI0616108A2 (pt) | 2005-09-23 | 2011-06-07 | Hoffmann La Roche | formulação de dosagem |
AR060403A1 (es) * | 2006-04-12 | 2008-06-11 | Sanofi Aventis | Compuestos de amino- pirimidina 2,6- sustituidos -4- monosustituidos como antagonistas del receptor de prostaglandina d2 |
MX2009001494A (es) * | 2006-08-07 | 2009-04-23 | Albany Molecular Res Inc | 2-aminobenzoxazol carboxamidas como moduladores 5ht3. |
GB0808747D0 (en) | 2008-05-14 | 2008-06-18 | Glaxo Wellcome Mfg Pte Ltd | Novel compounds |
WO2011054773A1 (en) | 2009-11-03 | 2011-05-12 | Glaxosmithkline Llc | Novel lactam compounds |
US8426450B1 (en) | 2011-11-29 | 2013-04-23 | Helsinn Healthcare Sa | Substituted 4-phenyl pyridines having anti-emetic effect |
-
2014
- 2014-11-06 CN CN201480060999.7A patent/CN105745198B/zh not_active Expired - Fee Related
- 2014-11-06 MX MX2016006004A patent/MX368070B/es active IP Right Grant
- 2014-11-06 RU RU2016122464A patent/RU2673084C2/ru not_active IP Right Cessation
- 2014-11-06 ES ES14860761.7T patent/ES2671418T3/es active Active
- 2014-11-06 EP EP14860761.7A patent/EP3067349B1/en not_active Not-in-force
- 2014-11-06 US US15/034,808 patent/US10100030B2/en not_active Expired - Fee Related
- 2014-11-06 JP JP2014555442A patent/JP5806420B1/ja not_active Expired - Fee Related
- 2014-11-06 WO PCT/JP2014/079384 patent/WO2015068744A1/ja active Application Filing
- 2014-11-06 KR KR1020167013135A patent/KR20160078997A/ko active IP Right Grant
- 2014-11-06 TW TW103138516A patent/TWI657082B/zh not_active IP Right Cessation
- 2014-11-06 BR BR112016009811A patent/BR112016009811A2/pt not_active IP Right Cessation
- 2014-11-06 AU AU2014347644A patent/AU2014347644B2/en not_active Ceased
- 2014-11-06 CA CA2930008A patent/CA2930008A1/en not_active Abandoned
- 2014-11-06 PL PL14860761T patent/PL3067349T3/pl unknown
-
2016
- 2016-04-21 IL IL245286A patent/IL245286B/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
TW201605823A (zh) | 2016-02-16 |
MX2016006004A (es) | 2016-08-12 |
IL245286B (en) | 2019-09-26 |
US20160289206A1 (en) | 2016-10-06 |
RU2673084C2 (ru) | 2018-11-22 |
EP3067349A1 (en) | 2016-09-14 |
AU2014347644B2 (en) | 2018-06-14 |
US10100030B2 (en) | 2018-10-16 |
WO2015068744A1 (ja) | 2015-05-14 |
EP3067349B1 (en) | 2018-02-28 |
RU2016122464A3 (pl) | 2018-06-25 |
IL245286A0 (en) | 2016-06-30 |
MX368070B (es) | 2019-09-18 |
AU2014347644A1 (en) | 2016-05-19 |
CN105745198B (zh) | 2018-09-21 |
BR112016009811A2 (pt) | 2017-12-05 |
ES2671418T3 (es) | 2018-06-06 |
JPWO2015068744A1 (ja) | 2017-03-09 |
CA2930008A1 (en) | 2015-05-14 |
TWI657082B (zh) | 2019-04-21 |
RU2016122464A (ru) | 2017-12-11 |
JP5806420B1 (ja) | 2015-11-10 |
KR20160078997A (ko) | 2016-07-05 |
EP3067349A4 (en) | 2016-12-28 |
CN105745198A (zh) | 2016-07-06 |
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