PL3010537T3 - Sposoby zapobiegania agregacji komponentów wirusowych - Google Patents
Sposoby zapobiegania agregacji komponentów wirusowychInfo
- Publication number
- PL3010537T3 PL3010537T3 PL14734942T PL14734942T PL3010537T3 PL 3010537 T3 PL3010537 T3 PL 3010537T3 PL 14734942 T PL14734942 T PL 14734942T PL 14734942 T PL14734942 T PL 14734942T PL 3010537 T3 PL3010537 T3 PL 3010537T3
- Authority
- PL
- Poland
- Prior art keywords
- aggregation
- prevention
- methods
- viral components
- viral
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/125—Picornaviridae, e.g. calicivirus
- A61K39/13—Poliovirus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/145—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5252—Virus inactivated (killed)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16051—Methods of production or purification of viral material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18051—Methods of production or purification of viral material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/32011—Picornaviridae
- C12N2770/32051—Methods of production or purification of viral material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/32011—Picornaviridae
- C12N2770/32311—Enterovirus
- C12N2770/32323—Virus like particles [VLP]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/32011—Picornaviridae
- C12N2770/32311—Enterovirus
- C12N2770/32334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/32011—Picornaviridae
- C12N2770/32311—Enterovirus
- C12N2770/32351—Methods of production or purification of viral material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/32011—Picornaviridae
- C12N2770/32611—Poliovirus
- C12N2770/32634—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/32011—Picornaviridae
- C12N2770/32611—Poliovirus
- C12N2770/32651—Methods of production or purification of viral material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/32011—Picornaviridae
- C12N2770/32611—Poliovirus
- C12N2770/32661—Methods of inactivation or attenuation
- C12N2770/32663—Methods of inactivation or attenuation by chemical treatment
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Mycology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13172263 | 2013-06-17 | ||
| EP14734942.7A EP3010537B1 (en) | 2013-06-17 | 2014-06-17 | Methods for the prevention of aggregation of viral components |
| PCT/NL2014/050395 WO2014204303A2 (en) | 2013-06-17 | 2014-06-17 | Methods for the prevention of aggregation of viral components |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3010537T3 true PL3010537T3 (pl) | 2019-03-29 |
Family
ID=48625913
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL14734942T PL3010537T3 (pl) | 2013-06-17 | 2014-06-17 | Sposoby zapobiegania agregacji komponentów wirusowych |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US10080793B2 (pl) |
| EP (1) | EP3010537B1 (pl) |
| KR (1) | KR102219672B1 (pl) |
| CN (1) | CN105517568B (pl) |
| BR (1) | BR112015031541A2 (pl) |
| DK (1) | DK3010537T3 (pl) |
| ES (1) | ES2689150T3 (pl) |
| HK (1) | HK1223845A1 (pl) |
| HR (1) | HRP20181606T1 (pl) |
| HU (1) | HUE040108T2 (pl) |
| LT (1) | LT3010537T (pl) |
| PL (1) | PL3010537T3 (pl) |
| PT (1) | PT3010537T (pl) |
| RS (1) | RS57864B1 (pl) |
| SI (1) | SI3010537T1 (pl) |
| WO (1) | WO2014204303A2 (pl) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11160857B2 (en) * | 2015-06-15 | 2021-11-02 | Emory University | Multivalent enterovirus vaccine compositions and uses related thereto |
| WO2019155492A1 (en) * | 2018-02-07 | 2019-08-15 | Bharat Biotech International Limited | A process for enterovirus purification and inactivation and vaccine compositions obtained thereof |
| WO2019191586A2 (en) * | 2018-03-30 | 2019-10-03 | Biological Mimetics, Inc. | Irradiation-inactivated poliovirus, compositions including the same, and methods of preparation |
| CN108578399B (zh) * | 2018-07-10 | 2020-01-07 | 湖北工业大学 | 氨基酸酯化合物在制备抗cvb3病毒药物中的应用 |
| JP2022546400A (ja) * | 2019-08-30 | 2022-11-04 | カシーヴ バイオサイエンシズ，リミテッド・ライアビリティ・カンパニー | 高濃度の薬理学的に活性な抗体の新規製剤 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE163547T1 (de) * | 1989-08-15 | 1998-03-15 | Massachusetts Inst Technology | Stabilisierte impfstoffzusammensetzungen |
| BRPI0418093A (pt) | 2003-12-24 | 2007-04-17 | Nederlanden Staat | vìrion de um pneumovìrus, método para produzir vìrions pneumovirais, composição, uso de um vìrion, e, método para a prevenção ou tratamento de uma infecção pneumoviral |
| US8084032B2 (en) | 2004-01-21 | 2011-12-27 | Ajinomoto Co., Inc. | Purification method which prevents denaturation of an antibody |
| CN101018858A (zh) * | 2004-06-01 | 2007-08-15 | 建新公司 | 防止aav载体聚集的组合物和方法 |
| EP4170024A1 (en) | 2004-06-01 | 2023-04-26 | Genzyme Corporation | Compositions and methods to prevent aav vector aggregation |
| EA010057B1 (ru) * | 2004-08-27 | 2008-06-30 | Панацея Биотек Лтд. | Инактивированная полиомиелитная вакцина, полученная из штамма сейбина вируса полиомиелита |
| EP3124044A1 (en) | 2007-09-14 | 2017-02-01 | Sanofi Pasteur Biologics, LLC | Pharmaceutical compositions containing clostridium difficile toxoids a and b |
| SG177655A1 (en) | 2009-07-16 | 2012-02-28 | Crucell Holland Bv | Production of polio virus at high titers for vaccine production |
| TW201307561A (zh) * | 2011-04-29 | 2013-02-16 | 腫瘤防治生化科技公司 | 使用凝膠滲透層析法純化病毒之方法 |
-
2014
- 2014-06-17 RS RS20181159A patent/RS57864B1/sr unknown
- 2014-06-17 DK DK14734942.7T patent/DK3010537T3/en active
- 2014-06-17 KR KR1020157037129A patent/KR102219672B1/ko active IP Right Grant
- 2014-06-17 ES ES14734942.7T patent/ES2689150T3/es active Active
- 2014-06-17 EP EP14734942.7A patent/EP3010537B1/en active Active
- 2014-06-17 WO PCT/NL2014/050395 patent/WO2014204303A2/en active Application Filing
- 2014-06-17 LT LTEP14734942.7T patent/LT3010537T/lt unknown
- 2014-06-17 SI SI201430844T patent/SI3010537T1/sl unknown
- 2014-06-17 PT PT147349427T patent/PT3010537T/pt unknown
- 2014-06-17 PL PL14734942T patent/PL3010537T3/pl unknown
- 2014-06-17 HU HUE14734942A patent/HUE040108T2/hu unknown
- 2014-06-17 BR BR112015031541A patent/BR112015031541A2/pt not_active Application Discontinuation
- 2014-06-17 US US14/898,654 patent/US10080793B2/en active Active
- 2014-06-17 CN CN201480034489.2A patent/CN105517568B/zh active Active
-
2016
- 2016-10-25 HK HK16112260.0A patent/HK1223845A1/zh unknown
-
2018
- 2018-10-04 HR HRP20181606TT patent/HRP20181606T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HK1223845A1 (zh) | 2017-08-11 |
| HUE040108T2 (hu) | 2019-02-28 |
| CN105517568A (zh) | 2016-04-20 |
| SI3010537T1 (sl) | 2018-09-28 |
| CN105517568B (zh) | 2020-07-07 |
| KR102219672B1 (ko) | 2021-02-25 |
| EP3010537A2 (en) | 2016-04-27 |
| BR112015031541A2 (pt) | 2017-07-25 |
| EP3010537B1 (en) | 2018-07-11 |
| US10080793B2 (en) | 2018-09-25 |
| PT3010537T (pt) | 2019-12-03 |
| DK3010537T3 (en) | 2018-09-24 |
| US20160184423A1 (en) | 2016-06-30 |
| KR20160019477A (ko) | 2016-02-19 |
| WO2014204303A2 (en) | 2014-12-24 |
| RS57864B1 (sr) | 2018-12-31 |
| HRP20181606T1 (hr) | 2018-11-30 |
| ES2689150T3 (es) | 2018-11-08 |
| WO2014204303A3 (en) | 2015-10-08 |
| LT3010537T (lt) | 2018-10-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HK1223402A1 (zh) | 免疫溶瘤療法 | |
| ZA201509117B (en) | Process for the preparation of butadiene | |
| TWI562535B (en) | High frequency component | |
| HRP20181606T1 (hr) | Postupci za sprječavanje agregacije virusnih komponenti | |
| AU353247S (en) | Single suite | |
| IL245474A0 (en) | Process for the preparation of 5-fluoro-1h-pyrazoles | |
| IL245476B (en) | Process for the preparation of 5-fluoro-1h-pyrazoles | |
| IL281072B (en) | Processes for the preparation of pyrimidinylcyclopentane compounds | |
| IL229326A (en) | Process for making n-iodine-affluent | |
| GB201308442D0 (en) | Duplexer | |
| PL2995007T3 (pl) | Duplekser | |
| EP2975687A4 (en) | DUPLEXER | |
| IL246188B (en) | A process for the preparation of tiacomycin | |
| GB201314063D0 (en) | Virus | |
| GB201306812D0 (en) | Virus | |
| EP3070122A4 (en) | INTERIOR COMPONENT | |
| PT2984100T (pt) | Processo para a preparação de drospirenona | |
| GB201308362D0 (en) | Rumbles |