PL2961407T3 - Sole pochodnych 2-amino-1-hydroksyetylo-8-hydroksychinolin-2(1h)-onu wykazujące zarówno aktywność agonisty receptora β2-adrenergicznego jak i aktywność antagonisty receptora muskarynowego M3 - Google Patents

Sole pochodnych 2-amino-1-hydroksyetylo-8-hydroksychinolin-2(1h)-onu wykazujące zarówno aktywność agonisty receptora β2-adrenergicznego jak i aktywność antagonisty receptora muskarynowego M3

Info

Publication number
PL2961407T3
PL2961407T3 PL14706652T PL14706652T PL2961407T3 PL 2961407 T3 PL2961407 T3 PL 2961407T3 PL 14706652 T PL14706652 T PL 14706652T PL 14706652 T PL14706652 T PL 14706652T PL 2961407 T3 PL2961407 T3 PL 2961407T3
Authority
PL
Poland
Prior art keywords
hydroxyquinolin
hydroxyethyl
derivatives
salts
amino
Prior art date
Application number
PL14706652T
Other languages
English (en)
Inventor
Francesc Carrera Carrera
Francesca Pajuelo Lorenzo
Juan Antonio Perez Andres
Maria PRAT QUIÑONES
Carlos Puig Duran
Montserrat Julia Jane
Original Assignee
Almirall S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47827112&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2961407(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Almirall S.A. filed Critical Almirall S.A.
Publication of PL2961407T3 publication Critical patent/PL2961407T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01—Sulfonic acids
    • C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
    • C07C309/03—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C309/05—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing at least two sulfo groups bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235—Saturated compounds containing more than one carboxyl group
    • C07C59/245—Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
    • C07C59/255—Tartaric acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D275/06—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to the ring sulfur atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs
PL14706652T 2013-02-27 2014-02-27 Sole pochodnych 2-amino-1-hydroksyetylo-8-hydroksychinolin-2(1h)-onu wykazujące zarówno aktywność agonisty receptora β2-adrenergicznego jak i aktywność antagonisty receptora muskarynowego M3 PL2961407T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP13382060 2013-02-27
US201361804558P 2013-03-22 2013-03-22
PCT/EP2014/053871 WO2014131851A1 (en) 2013-02-27 2014-02-27 SALTS OF 2-AMINO-1-HYDROXYETHYL-8-HYDROXYQUINOLIN-2(1H)-ONE DERIVATIVES HAVING BOTH β2 ADRENERGIC RECEPTOR AGONIST AND M3 MUSCARINIC RECEPTOR ANTAGONIST ACTIVITIES
EP14706652.6A EP2961407B1 (en) 2013-02-27 2014-02-27 Salts of 2-amino-1-hydroxyethyl-8-hydroxyquinolin-2(1h)-one derivatives having both 2 adrenergic receptor agonist and m3 muscarinic receptor antagonist activities

Publications (1)

Publication Number Publication Date
PL2961407T3 true PL2961407T3 (pl) 2018-10-31

Family

ID=47827112

Family Applications (1)

Application Number Title Priority Date Filing Date
PL14706652T PL2961407T3 (pl) 2013-02-27 2014-02-27 Sole pochodnych 2-amino-1-hydroksyetylo-8-hydroksychinolin-2(1h)-onu wykazujące zarówno aktywność agonisty receptora β2-adrenergicznego jak i aktywność antagonisty receptora muskarynowego M3

Country Status (33)

Country Link
US (1) US9562039B2 (pl)
EP (1) EP2961407B1 (pl)
JP (1) JP6364429B2 (pl)
KR (1) KR102002668B1 (pl)
CN (1) CN105025897B (pl)
AR (2) AR094911A1 (pl)
AU (1) AU2014222645B2 (pl)
BR (1) BR112015020152B1 (pl)
CA (1) CA2901865C (pl)
CL (1) CL2015002402A1 (pl)
CR (1) CR20150427A (pl)
DK (1) DK2961407T3 (pl)
DO (1) DOP2015000197A (pl)
EA (1) EA028566B1 (pl)
ES (1) ES2674085T3 (pl)
HK (1) HK1212246A1 (pl)
HR (1) HRP20181097T1 (pl)
HU (1) HUE039303T2 (pl)
IL (1) IL240278B (pl)
LT (1) LT2961407T (pl)
MX (2) MX358624B (pl)
MY (1) MY180350A (pl)
PE (1) PE20151602A1 (pl)
PH (1) PH12015501754A1 (pl)
PL (1) PL2961407T3 (pl)
PT (1) PT2961407T (pl)
RS (1) RS57297B1 (pl)
SG (1) SG11201505868QA (pl)
SI (1) SI2961407T1 (pl)
TW (1) TWI643853B (pl)
UY (1) UY35355A (pl)
WO (1) WO2014131851A1 (pl)
ZA (1) ZA201505374B (pl)

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TW201617343A (zh) 2014-09-26 2016-05-16 阿爾米雷爾有限公司 具有β２腎上腺素促效劑及Ｍ３蕈毒拮抗劑活性之新穎雙環衍生物

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KR102002668B1 (ko) 2019-07-23
CR20150427A (es) 2015-11-18
CN105025897A (zh) 2015-11-04
JP6364429B2 (ja) 2018-07-25
EA201500875A1 (ru) 2016-06-30
AU2014222645A1 (en) 2015-08-13
TWI643853B (zh) 2018-12-11
HRP20181097T1 (hr) 2018-09-07
IL240278B (en) 2019-08-29
BR112015020152A2 (pt) 2017-07-18
MX2015010680A (es) 2017-09-08
US9562039B2 (en) 2017-02-07
DOP2015000197A (es) 2015-09-30
UY35355A (es) 2014-09-30
RS57297B1 (sr) 2018-08-31
DK2961407T3 (en) 2018-05-28
SG11201505868QA (en) 2015-09-29
AU2014222645B2 (en) 2017-11-30
PT2961407T (pt) 2018-05-18
HUE039303T2 (hu) 2018-12-28
HK1212246A1 (en) 2016-06-10
BR112015020152B1 (pt) 2021-01-26
SI2961407T1 (en) 2018-07-31
TW201443043A (zh) 2014-11-16
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