PL2946791T3 - Przeciwciała anty-CD277 i ich zastosowania - Google Patents

Przeciwciała anty-CD277 i ich zastosowania

Info

Publication number
PL2946791T3
PL2946791T3 PL15151003T PL15151003T PL2946791T3 PL 2946791 T3 PL2946791 T3 PL 2946791T3 PL 15151003 T PL15151003 T PL 15151003T PL 15151003 T PL15151003 T PL 15151003T PL 2946791 T3 PL2946791 T3 PL 2946791T3
Authority
PL
Poland
Prior art keywords
antibodies
Prior art date
Application number
PL15151003T
Other languages
English (en)
Inventor
Daniel Olive
Marc Bonneville
Emmanuel Scotet
Christelle HARLY
Yves GUILLAUME
Original Assignee
INSERM (Institut National de la Santé et de la Recherche Médicale)
Université D'aix-Marseille
Institut Jean Paoli & Irène Calmettes
Universite De Nantes
Centre National De La Recherche Scientifique (Cnrs)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by INSERM (Institut National de la Santé et de la Recherche Médicale), Université D'aix-Marseille, Institut Jean Paoli & Irène Calmettes, Universite De Nantes, Centre National De La Recherche Scientifique (Cnrs) filed Critical INSERM (Institut National de la Santé et de la Recherche Médicale)
Publication of PL2946791T3 publication Critical patent/PL2946791T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55Fab or Fab'
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/75Agonist effect on antigen

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Transplantation (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Fats And Perfumes (AREA)
PL15151003T 2010-12-15 2011-12-14 Przeciwciała anty-CD277 i ich zastosowania PL2946791T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
PCT/IB2010/003417 WO2012080769A1 (en) 2010-12-15 2010-12-15 Anti-cd277 antibodies and uses thereof
EP15151003.9A EP2946791B1 (en) 2010-12-15 2011-12-14 Anti-CD277 antibodies and uses thereof
PCT/EP2011/072787 WO2012080351A1 (en) 2010-12-15 2011-12-14 Anti-cd277 antibodies and uses thereof
EP11802346.4A EP2651441A1 (en) 2010-12-15 2011-12-14 Anti-cd277 antibodies and uses thereof

Publications (1)

Publication Number Publication Date
PL2946791T3 true PL2946791T3 (pl) 2022-02-21

Family

ID=43828073

Family Applications (1)

Application Number Title Priority Date Filing Date
PL15151003T PL2946791T3 (pl) 2010-12-15 2011-12-14 Przeciwciała anty-CD277 i ich zastosowania

Country Status (14)

Country Link
US (1) US20140322235A1 (pl)
EP (3) EP3915582A3 (pl)
JP (2) JP6138693B2 (pl)
CY (1) CY1125057T1 (pl)
ES (1) ES2899733T3 (pl)
HR (1) HRP20211823T1 (pl)
HU (1) HUE057004T2 (pl)
LT (1) LT2946791T (pl)
PL (1) PL2946791T3 (pl)
PT (1) PT2946791T (pl)
RS (1) RS62700B1 (pl)
SI (1) SI2946791T1 (pl)
SM (1) SMT202100676T1 (pl)
WO (2) WO2012080769A1 (pl)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU653752B2 (en) 1990-09-25 1994-10-13 Ethicon Inc. Bone fastener
US20150353643A1 (en) * 2013-09-24 2015-12-10 Universite De La Mediterranee - Aix-Marseille Ii Anti-cd277 antibodies and uses thereof
EP3490675A4 (en) * 2016-07-29 2020-07-29 New York University T GAMMA DELTA LYMPHOCYTES USED AS A TARGET FOR THE TREATMENT OF SOLID TUMORS
WO2018082590A1 (zh) * 2016-11-02 2018-05-11 北京蛋白质组研究中心 肿瘤免疫治疗靶标及其应用
WO2018201130A1 (en) * 2017-04-28 2018-11-01 The Brigham And Women's Hospital, Inc. Targeting gamma-delta t cells in obesity and cachexia
MX2020003219A (es) * 2017-09-21 2020-07-20 Imcheck Therapeutics Sas Anticuerpos que tienen especificidad para btn2 y usos de los mismos.
US10519236B2 (en) 2018-01-23 2019-12-31 New York University Antibodies specific to delta 1 chain of T cell receptor
WO2019211369A1 (en) * 2018-05-03 2019-11-07 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical compositions for treating cancer
WO2019211370A1 (en) 2018-05-03 2019-11-07 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical compositions for treating cancer
IL280563B2 (en) 2018-08-01 2024-10-01 Imcheck Therapeutics Sas Anti-btn3a antibodies and their use in treating cancer or infectious disorders
US12460004B2 (en) 2018-08-09 2025-11-04 Compass Therapeutics Llc Antibodies that bind CD277 and uses thereof
WO2020033925A2 (en) * 2018-08-09 2020-02-13 Compass Therapeutics Llc Antibodies that bind cd277 and uses thereof
US20210388089A1 (en) * 2018-08-09 2021-12-16 Compass Therapeutics Llc Antigen binding agents that bind cd277 and uses thereof
AU2019406662A1 (en) * 2018-12-18 2021-06-17 Merck Sharp & Dohme Llc Methods of using butyrophilin antibodies for treating HIV infection
CN113412281B (zh) * 2018-12-26 2024-07-23 感应检查疗法公司 Btn3a结合蛋白及其用途
WO2020154548A2 (en) 2019-01-23 2020-07-30 New York University Antibodies specific to delta 1 chain of t cell receptor
JP7652705B2 (ja) 2019-03-20 2025-03-27 イムチェック セラピューティクス エスエーエス Btn2に対する特異性を有する抗体及びその使用
JP2024507735A (ja) * 2021-02-08 2024-02-21 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア ブチロフィリンサブファミリー3メンバーa1(btn3a1、cd277)の制御
TW202313695A (zh) 2021-09-15 2023-04-01 法商感應檢查療法公司 抗btn3a抗體在製備用於治療腫瘤的藥物的用途
WO2023052541A1 (en) 2021-09-30 2023-04-06 Imcheck Therapeutics Combination of an anti-btn3a activating antibody and an il-2 agonist for use in therapy
US20250129165A1 (en) 2021-10-27 2025-04-24 Imcheck Therapeutics Butyrophilin (btn) 3a activating antibodies for use in methods for treating infectious disorders
CN119173528A (zh) 2022-02-27 2024-12-20 勃林格殷格翰国际公司 针对cd277和肿瘤抗原的双特异性抗体
US20250353909A1 (en) 2022-05-10 2025-11-20 Imcheck Therapeutics Anti-btn3a antibodies for use in methods of treating gastro-intestinal inflammatory disorders
CA3266717A1 (en) 2022-10-04 2024-04-11 Institut Jean Paoli & Irene Calmettes COMBINATION OF A BTN3A ACTIVATING ANTIBODY, A BCL2 INHIBITOR AND A HYPOMETHYLATING AGENT INTENDED FOR USE IN THE TREATMENT OF CANCER
CN120813377A (zh) 2023-02-23 2025-10-17 感应检查疗法公司 Btn3a活化抗体和免疫检查点抑制剂的组合
TW202506731A (zh) 2023-04-27 2025-02-16 法商感應檢查療法公司 治療多重抗藥性細菌感染之方法
WO2024261239A1 (en) 2023-06-23 2024-12-26 Imcheck Therapeutics Bispecific antibodies targeting btn3a and the pd-1/pd-l1 inhibitory axis
CN119193482A (zh) * 2024-11-26 2024-12-27 北京国卫生物科技有限公司 一种γδT细胞体外诱导培养方法

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4179337A (en) 1973-07-20 1979-12-18 Davis Frank F Non-immunogenic polypeptides
JPS6023084B2 (ja) 1979-07-11 1985-06-05 味の素株式会社 代用血液
US4640835A (en) 1981-10-30 1987-02-03 Nippon Chemiphar Company, Ltd. Plasminogen activator derivatives
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4496689A (en) 1983-12-27 1985-01-29 Miles Laboratories, Inc. Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer
EP0173494A3 (en) 1984-08-27 1987-11-25 The Board Of Trustees Of The Leland Stanford Junior University Chimeric receptors by dna splicing and expression
EP0206448B1 (en) 1985-06-19 1990-11-14 Ajinomoto Co., Inc. Hemoglobin combined with a poly(alkylene oxide)
JPS63501765A (ja) 1985-11-01 1988-07-21 インタ−ナショナル、ジェネティック、エンジニアリング インコ−ポレ−テッド 抗体遺伝子のモジュ−ル組立体、それにより産生された抗体及び用途
WO1987005330A1 (en) 1986-03-07 1987-09-11 Michel Louis Eugene Bergh Method for enhancing glycoprotein stability
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
US4861719A (en) 1986-04-25 1989-08-29 Fred Hutchinson Cancer Research Center DNA constructs for retrovirus packaging cell lines
US4791192A (en) 1986-06-26 1988-12-13 Takeda Chemical Industries, Ltd. Chemically modified protein with polyethyleneglycol
US5202238A (en) 1987-10-27 1993-04-13 Oncogen Production of chimeric antibodies by homologous recombination
US5204244A (en) 1987-10-27 1993-04-20 Oncogen Production of chimeric antibodies by homologous recombination
US5278056A (en) 1988-02-05 1994-01-11 The Trustees Of Columbia University In The City Of New York Retroviral packaging cell lines and process of using same
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
GB8928874D0 (en) 1989-12-21 1990-02-28 Celltech Ltd Humanised antibodies
US5859205A (en) 1989-12-21 1999-01-12 Celltech Limited Humanised antibodies
US5670488A (en) 1992-12-03 1997-09-23 Genzyme Corporation Adenovirus vector for gene therapy
DE69233482T2 (de) 1991-05-17 2006-01-12 Merck & Co., Inc. Verfahren zur Verminderung der Immunogenität der variablen Antikörperdomänen
US5565332A (en) 1991-09-23 1996-10-15 Medical Research Council Production of chimeric antibodies - a combinatorial approach
US5639641A (en) 1992-09-09 1997-06-17 Immunogen Inc. Resurfacing of rodent antibodies
DE69434860T2 (de) 1993-02-22 2007-03-15 The Rockefeller University Herstellung von helfer-freien retroviren mit hohem titer mittels transienter transfektion
FR2712812B1 (fr) 1993-11-23 1996-02-09 Centre Nat Rech Scient Composition pour la production de produits thérapeutiques in vivo.
HU221385B1 (en) 1994-07-13 2002-09-28 Chugai Pharmaceutical Co Ltd Reconstituted human antibody against human interleukin-8
IL116816A (en) 1995-01-20 2003-05-29 Rhone Poulenc Rorer Sa Cell for the production of a defective recombinant adenovirus or an adeno-associated virus and the various uses thereof
CN1241944C (zh) 1995-09-11 2006-02-15 协和发酵工业株式会社 抗人白介素-5受体α链的抗体
US6013516A (en) 1995-10-06 2000-01-11 The Salk Institute For Biological Studies Vector and method of use for nucleic acid delivery to non-dividing cells
EP0971952A2 (en) 1997-04-10 2000-01-19 Royal Netherlands Academy of Arts and Sciences Diagnosis method and reagents

Also Published As

Publication number Publication date
HUE057004T2 (hu) 2022-04-28
EP2946791A1 (en) 2015-11-25
EP2651441A1 (en) 2013-10-23
LT2946791T (lt) 2022-01-10
WO2012080769A1 (en) 2012-06-21
JP2014503522A (ja) 2014-02-13
CY1125057T1 (el) 2023-06-09
EP3915582A3 (en) 2021-12-08
EP3915582A2 (en) 2021-12-01
US20140322235A1 (en) 2014-10-30
WO2012080351A1 (en) 2012-06-21
ES2899733T3 (es) 2022-03-14
JP6138693B2 (ja) 2017-05-31
JP2017061502A (ja) 2017-03-30
RS62700B1 (sr) 2022-01-31
SI2946791T1 (sl) 2022-02-28
SMT202100676T1 (it) 2022-01-10
EP2946791B1 (en) 2021-09-08
JP6408534B2 (ja) 2018-10-17
HRP20211823T1 (hr) 2022-03-04
PT2946791T (pt) 2021-12-07

Similar Documents

Publication Publication Date Title
IL288203B (en) Meditops and Meditop binding antibodies and their use
IL281250A (en) Anti-PHF-tau antibodies and uses thereof
IL259436A (en) Antibodies against 3angptl and their uses
SMT202100676T1 (it) Anticorpi anti-cd277 e loro usi
IL232399A0 (en) Anti-2fgfr antibodies and their use
EP2533810A4 (en) CD20 ANTIBODIES AND ITS USE
IL225484A0 (en) Anti-48cd antibodies and their uses
EP2756094A4 (en) ANTI-B7-H4 ANTIBODIES AND USES THEREOF
EP2494062A4 (en) ANTI-GLP-1R ANTIBODIES AND THEIR USES
ZA201107486B (en) Anti-tnf-x antibodies and their uses
PL2621955T3 (pl) Przeciwciała anty-CEACAM6 i ich zastosowania
SG10201501285RA (en) Anti-alpha2 integrin antibodies and their uses
IL220536A0 (en) Anti - bv8 antibodies and uses thereof
IL214527A0 (en) Anti-mst1r antibodies and uses thereof
HK1188458A (en) Anti-sod1 antibodies and uses thereof