PL2841593T3 - Dehydrogenaza i toksyna clostridium difficile jako biomarker - Google Patents

Dehydrogenaza i toksyna clostridium difficile jako biomarker

Info

Publication number
PL2841593T3
PL2841593T3 PL12838635T PL12838635T PL2841593T3 PL 2841593 T3 PL2841593 T3 PL 2841593T3 PL 12838635 T PL12838635 T PL 12838635T PL 12838635 T PL12838635 T PL 12838635T PL 2841593 T3 PL2841593 T3 PL 2841593T3
Authority
PL
Poland
Prior art keywords
biomarker
toxin
clostridium difficile
dehydrogenase
difficile dehydrogenase
Prior art date
Application number
PL12838635T
Other languages
English (en)
Inventor
James Hunter Boone
David M. Lyerly
Robert J. Carman
Original Assignee
Techlab, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US13/457,049 external-priority patent/US20120276059A1/en
Application filed by Techlab, Inc. filed Critical Techlab, Inc.
Publication of PL2841593T3 publication Critical patent/PL2841593T3/pl

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/33—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Clostridium (G)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/79—Transferrins, e.g. lactoferrins, ovotransferrins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/902—Oxidoreductases (1.)
    • G01N2333/906—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.7)
    • G01N2333/90605—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.7) acting on the CH-NH2 group of donors (1.4)
    • G01N2333/90611—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.7) acting on the CH-NH2 group of donors (1.4) with NAD or NADP as acceptor (1.4.1) in general
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/902—Oxidoreductases (1.)
    • G01N2333/906—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.7)
    • G01N2333/90605—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.7) acting on the CH-NH2 group of donors (1.4)
    • G01N2333/90611—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.7) acting on the CH-NH2 group of donors (1.4) with NAD or NADP as acceptor (1.4.1) in general
    • G01N2333/90616—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.7) acting on the CH-NH2 group of donors (1.4) with NAD or NADP as acceptor (1.4.1) in general with a definite EC number (1.4.1.-)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/56—Staging of a disease; Further complications associated with the disease

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
PL12838635T 2012-04-26 2012-10-31 Dehydrogenaza i toksyna clostridium difficile jako biomarker PL2841593T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US13/457,049 US20120276059A1 (en) 2011-04-29 2012-04-26 Fecal lactoferrin as a biomarker for determining disease severity and for monitoring infection in patients with clostridium difficile disease
US13/664,383 US10295535B2 (en) 2011-04-29 2012-10-30 Clostridium difficile dehydrogenase and toxin as a biomarker for monitoring infection in patients with clostridium difficile disease and differentiating carrier state from active disease
PCT/US2012/062757 WO2013052973A1 (en) 2012-04-26 2012-10-31 Clostridium difficile dehydrogenase and toxin as a biomarker
EP12838635.6A EP2841593B1 (en) 2012-04-26 2012-10-31 Clostridium difficile dehydrogenase and toxin as a biomarker

Publications (1)

Publication Number Publication Date
PL2841593T3 true PL2841593T3 (pl) 2020-05-18

Family

ID=48044233

Family Applications (1)

Application Number Title Priority Date Filing Date
PL12838635T PL2841593T3 (pl) 2012-04-26 2012-10-31 Dehydrogenaza i toksyna clostridium difficile jako biomarker

Country Status (10)

Country Link
US (1) US10295535B2 (pl)
EP (1) EP2841593B1 (pl)
JP (1) JP6193976B2 (pl)
AU (1) AU2012318345B2 (pl)
CA (1) CA2871613C (pl)
ES (1) ES2764080T3 (pl)
HU (1) HUE049421T2 (pl)
PL (1) PL2841593T3 (pl)
PT (1) PT2841593T (pl)
WO (1) WO2013052973A1 (pl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10444123B2 (en) 2014-08-01 2019-10-15 The Brigham And Women's Hospital, Inc. Volatile organic compounds (VOCs) for the diagnosis of Clostridium difficile-associated diarrhea (CDAD)
CN108445212B (zh) * 2018-03-21 2019-03-26 杭州观梓健康科技有限公司 一种用于检测艰难梭菌的胶体金试纸条和试剂盒
US20230184779A1 (en) * 2019-05-29 2023-06-15 Washington University Methods of detecting clostridium difficile infections
CN113278075B (zh) * 2021-06-18 2021-12-14 芜湖森爱驰生物科技有限公司 一种炎症检测试剂盒
CN113402605B (zh) * 2021-06-18 2021-12-14 佛山迪安医学检验实验室有限公司 一种快速炎症检测试剂盒

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5965375A (en) 1997-04-04 1999-10-12 Biosite Diagnostics Diagnostic tests and kits for Clostridium difficile
JP2000155121A (ja) 1998-11-18 2000-06-06 Nitto Denko Corp 免疫学的検査法
US20030157113A1 (en) 1999-12-28 2003-08-21 Terman David S. Compositions and methods for treatment of neoplastic disease
DE60138829D1 (de) 2000-11-14 2009-07-09 Techlab Inc Verfahren zur unterscheidung des reizkolons von der entzündlichen darmerkrankung (inflammatory bowel disease, ibd) und zur überwachung von patienten mit ibd unter verwendung von endogenem gesamt-lactoferrin als marker
US7960100B1 (en) 2004-04-30 2011-06-14 Celera Corporation Colon cancer targets and uses thereof
CA2588420C (en) * 2004-11-24 2014-12-23 Techlab, Inc. Device and method for detection of analytes
EP2252702B1 (en) 2008-02-08 2014-01-29 Mayo Foundation for Medical Education and Research Detection of clostridium difficile
CA2714720A1 (en) 2008-02-28 2009-09-03 3M Innovative Properties Company Antibodies to clostridium difficile spores and uses thereof
JP5324534B2 (ja) 2010-07-29 2013-10-23 株式会社日立ハイテクノロジーズ 検査方法及び装置
US20120276060A1 (en) * 2011-04-29 2012-11-01 Techlab, Inc. Fecal lactoferrin as a biomarker for determining disease severity and for treating infection in patients with clostridium difficile disease

Also Published As

Publication number Publication date
AU2012318345B2 (en) 2018-10-04
EP2841593A4 (en) 2015-11-11
HUE049421T2 (hu) 2020-09-28
AU2012318345A1 (en) 2014-11-06
US20130052640A1 (en) 2013-02-28
WO2013052973A1 (en) 2013-04-11
JP6193976B2 (ja) 2017-09-06
PT2841593T (pt) 2020-01-17
US10295535B2 (en) 2019-05-21
JP2015515634A (ja) 2015-05-28
NZ701004A (en) 2016-09-30
EP2841593A1 (en) 2015-03-04
ES2764080T3 (es) 2020-06-02
EP2841593B1 (en) 2019-12-18
CA2871613C (en) 2018-04-17
CA2871613A1 (en) 2013-04-11

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