PT2841593T - Desidrogenase e toxina de clostridium difficile como um biomarcador - Google Patents
Desidrogenase e toxina de clostridium difficile como um biomarcadorInfo
- Publication number
- PT2841593T PT2841593T PT128386356T PT12838635T PT2841593T PT 2841593 T PT2841593 T PT 2841593T PT 128386356 T PT128386356 T PT 128386356T PT 12838635 T PT12838635 T PT 12838635T PT 2841593 T PT2841593 T PT 2841593T
- Authority
- PT
- Portugal
- Prior art keywords
- biomarker
- toxin
- clostridium difficile
- dehydrogenase
- difficile dehydrogenase
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
- G01N2333/33—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Clostridium (G)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/79—Transferrins, e.g. lactoferrins, ovotransferrins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/902—Oxidoreductases (1.)
- G01N2333/906—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.7)
- G01N2333/90605—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.7) acting on the CH-NH2 group of donors (1.4)
- G01N2333/90611—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.7) acting on the CH-NH2 group of donors (1.4) with NAD or NADP as acceptor (1.4.1) in general
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/902—Oxidoreductases (1.)
- G01N2333/906—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.7)
- G01N2333/90605—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.7) acting on the CH-NH2 group of donors (1.4)
- G01N2333/90611—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.7) acting on the CH-NH2 group of donors (1.4) with NAD or NADP as acceptor (1.4.1) in general
- G01N2333/90616—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.7) acting on the CH-NH2 group of donors (1.4) with NAD or NADP as acceptor (1.4.1) in general with a definite EC number (1.4.1.-)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/56—Staging of a disease; Further complications associated with the disease
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13/457,049 US20120276059A1 (en) | 2011-04-29 | 2012-04-26 | Fecal lactoferrin as a biomarker for determining disease severity and for monitoring infection in patients with clostridium difficile disease |
| US13/664,383 US10295535B2 (en) | 2011-04-29 | 2012-10-30 | Clostridium difficile dehydrogenase and toxin as a biomarker for monitoring infection in patients with clostridium difficile disease and differentiating carrier state from active disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2841593T true PT2841593T (pt) | 2020-01-17 |
Family
ID=48044233
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT128386356T PT2841593T (pt) | 2012-04-26 | 2012-10-31 | Desidrogenase e toxina de clostridium difficile como um biomarcador |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US10295535B2 (pt) |
| EP (1) | EP2841593B1 (pt) |
| JP (1) | JP6193976B2 (pt) |
| AU (1) | AU2012318345B2 (pt) |
| CA (1) | CA2871613C (pt) |
| ES (1) | ES2764080T3 (pt) |
| HU (1) | HUE049421T2 (pt) |
| PL (1) | PL2841593T3 (pt) |
| PT (1) | PT2841593T (pt) |
| WO (1) | WO2013052973A1 (pt) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10444123B2 (en) | 2014-08-01 | 2019-10-15 | The Brigham And Women's Hospital, Inc. | Volatile organic compounds (VOCs) for the diagnosis of Clostridium difficile-associated diarrhea (CDAD) |
| CN108445212B (zh) * | 2018-03-21 | 2019-03-26 | 杭州观梓健康科技有限公司 | 一种用于检测艰难梭菌的胶体金试纸条和试剂盒 |
| US20230184779A1 (en) * | 2019-05-29 | 2023-06-15 | Washington University | Methods of detecting clostridium difficile infections |
| CN113402605B (zh) * | 2021-06-18 | 2021-12-14 | 佛山迪安医学检验实验室有限公司 | 一种快速炎症检测试剂盒 |
| CN113278075B (zh) * | 2021-06-18 | 2021-12-14 | 芜湖森爱驰生物科技有限公司 | 一种炎症检测试剂盒 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5965375A (en) | 1997-04-04 | 1999-10-12 | Biosite Diagnostics | Diagnostic tests and kits for Clostridium difficile |
| JP2000155121A (ja) | 1998-11-18 | 2000-06-06 | Nitto Denko Corp | 免疫学的検査法 |
| US20030157113A1 (en) | 1999-12-28 | 2003-08-21 | Terman David S. | Compositions and methods for treatment of neoplastic disease |
| AU2002902A (en) | 2000-11-14 | 2002-05-27 | Techlab Inc | Method for differentiating irritable bowel syndrome from inflammatory bowel disease (ibd) and for monitoring persons with ibd using total endogenous lactoferrinas a marker |
| US7960100B1 (en) | 2004-04-30 | 2011-06-14 | Celera Corporation | Colon cancer targets and uses thereof |
| ES2564169T3 (es) | 2004-11-24 | 2016-03-18 | Techlab, Inc. | Dispositivo y método para la detección de analitos |
| EP2252702B1 (en) | 2008-02-08 | 2014-01-29 | Mayo Foundation for Medical Education and Research | Detection of clostridium difficile |
| CA2714720A1 (en) | 2008-02-28 | 2009-09-03 | 3M Innovative Properties Company | Antibodies to clostridium difficile spores and uses thereof |
| JP5324534B2 (ja) | 2010-07-29 | 2013-10-23 | 株式会社日立ハイテクノロジーズ | 検査方法及び装置 |
| US20120276060A1 (en) * | 2011-04-29 | 2012-11-01 | Techlab, Inc. | Fecal lactoferrin as a biomarker for determining disease severity and for treating infection in patients with clostridium difficile disease |
-
2012
- 2012-10-30 US US13/664,383 patent/US10295535B2/en active Active
- 2012-10-31 EP EP12838635.6A patent/EP2841593B1/en active Active
- 2012-10-31 AU AU2012318345A patent/AU2012318345B2/en active Active
- 2012-10-31 JP JP2015508933A patent/JP6193976B2/ja active Active
- 2012-10-31 PL PL12838635T patent/PL2841593T3/pl unknown
- 2012-10-31 PT PT128386356T patent/PT2841593T/pt unknown
- 2012-10-31 WO PCT/US2012/062757 patent/WO2013052973A1/en active Application Filing
- 2012-10-31 HU HUE12838635A patent/HUE049421T2/hu unknown
- 2012-10-31 CA CA2871613A patent/CA2871613C/en active Active
- 2012-10-31 ES ES12838635T patent/ES2764080T3/es active Active
Also Published As
| Publication number | Publication date |
|---|---|
| NZ701004A (en) | 2016-09-30 |
| HUE049421T2 (hu) | 2020-09-28 |
| CA2871613A1 (en) | 2013-04-11 |
| AU2012318345A1 (en) | 2014-11-06 |
| EP2841593A1 (en) | 2015-03-04 |
| JP6193976B2 (ja) | 2017-09-06 |
| EP2841593B1 (en) | 2019-12-18 |
| US10295535B2 (en) | 2019-05-21 |
| CA2871613C (en) | 2018-04-17 |
| ES2764080T3 (es) | 2020-06-02 |
| JP2015515634A (ja) | 2015-05-28 |
| EP2841593A4 (en) | 2015-11-11 |
| PL2841593T3 (pl) | 2020-05-18 |
| US20130052640A1 (en) | 2013-02-28 |
| WO2013052973A1 (en) | 2013-04-11 |
| AU2012318345B2 (en) | 2018-10-04 |
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