PL2841425T3 - Antybakteryjne pochodne chinoliny - Google Patents
Antybakteryjne pochodne chinolinyInfo
- Publication number
- PL2841425T3 PL2841425T3 PL13719524.4T PL13719524T PL2841425T3 PL 2841425 T3 PL2841425 T3 PL 2841425T3 PL 13719524 T PL13719524 T PL 13719524T PL 2841425 T3 PL2841425 T3 PL 2841425T3
- Authority
- PL
- Poland
- Prior art keywords
- quinoline derivatives
- antibacterial quinoline
- antibacterial
- derivatives
- quinoline
- Prior art date
Links
- 230000000844 anti-bacterial effect Effects 0.000 title 1
- 229940027991 antiseptic and disinfectant quinoline derivative Drugs 0.000 title 1
- 125000002943 quinolinyl group Chemical class N1=C(C=CC2=CC=CC=C12)* 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12165934 | 2012-04-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2841425T3 true PL2841425T3 (pl) | 2016-10-31 |
Family
ID=48227271
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL13719524.4T PL2841425T3 (pl) | 2012-04-27 | 2013-04-26 | Antybakteryjne pochodne chinoliny |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US9133167B2 (enExample) |
| EP (1) | EP2841425B1 (enExample) |
| JP (1) | JP6153604B2 (enExample) |
| KR (1) | KR102110355B1 (enExample) |
| CN (1) | CN104254527B (enExample) |
| AU (1) | AU2013254674B2 (enExample) |
| CA (1) | CA2869718C (enExample) |
| DK (1) | DK2841425T3 (enExample) |
| EA (1) | EA035443B1 (enExample) |
| ES (1) | ES2576491T3 (enExample) |
| IN (1) | IN2014MN02364A (enExample) |
| MX (1) | MX355050B (enExample) |
| PL (1) | PL2841425T3 (enExample) |
| WO (1) | WO2013160435A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013160431A1 (en) * | 2012-04-27 | 2013-10-31 | Janssen Pharmaceutica Nv | Antibacterial quinoline derivatives |
| JP2017523213A (ja) * | 2014-08-06 | 2017-08-17 | ノバルティス アーゲー | 抗菌薬としてのキノロン誘導体 |
| US10508097B2 (en) | 2016-03-07 | 2019-12-17 | The Global Alliance For Tb Drug Development, Inc. | Antibacterial compounds and uses thereof |
| KR102574912B1 (ko) * | 2016-08-17 | 2023-09-07 | 덕산네오룩스 주식회사 | 유기전기 소자용 화합물, 이를 이용한 유기전기소자 및 그 전자 장치 |
| WO2018048882A1 (en) | 2016-09-06 | 2018-03-15 | The Research Foundation For The State University Of New York | Positron imaging tomography imaging agent composition and method for bacterial infection |
| KR102695633B1 (ko) * | 2021-12-17 | 2024-08-14 | 한국화학연구원 | 피리미딘을 포함하는 테트라하이드로이소퀴놀린 유도체 및 이의 결핵 치료제 용도 |
| EP4493551A1 (en) | 2022-03-14 | 2025-01-22 | Slap Pharmaceuticals LLC | Multicyclic compounds |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2270123A1 (en) | 1996-10-28 | 1998-05-07 | Department Of The Army, U.S. Government | Compounds, compositions and methods for treating antibiotic-resistant infections |
| US6103905A (en) | 1997-06-19 | 2000-08-15 | Sepracor, Inc. | Quinoline-indole antimicrobial agents, uses and compositions related thereto |
| GB0118238D0 (en) * | 2001-07-26 | 2001-09-19 | Smithkline Beecham Plc | Medicaments |
| ATE463482T1 (de) | 2002-07-25 | 2010-04-15 | Janssen Pharmaceutica Nv | Chinolinderivate und deren verwendung als mycobakterielle inhibitoren |
| KR101150172B1 (ko) * | 2004-01-23 | 2012-05-25 | 얀센 파마슈티카 엔.브이. | 치환된 퀴놀린 및 마이코박테리아 저해제로서의 용도 |
| AP2507A (en) | 2004-01-23 | 2012-11-16 | Janssen Pharmaceutica Nv | Quinoline derivatives and use thereof as mycobacterial inhibitors. |
| AU2005210036B2 (en) | 2004-01-29 | 2010-12-23 | Janssen Pharmaceutica N.V. | Quinoline derivatives for use as mycobacterial inhibitors |
| ATE390925T1 (de) | 2004-05-28 | 2008-04-15 | Janssen Pharmaceutica Nv | Verwendung von substituierten chinolin-derivaten zur behandlung von arzneimittelresistenten mycobakteriellen erkrankungen |
| WO2005123081A2 (en) | 2004-06-22 | 2005-12-29 | Janssen Pharmaceutica N.V. | (2-benzyl-4-{4-[1-(tetrahydrofuran-3-carbonyl)-pyrrolidin-3-yl]-piperazin-1-yl}-piperidin-1-yl)-(3,5-trifluoromethyl-phenyl))-methanone for the treatment of schizophrenia |
| JP2008515395A (ja) | 2004-09-28 | 2008-05-15 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | 細菌のａｔｐ合成酵素の結合ドメイン |
| EE05394B1 (et) | 2004-12-24 | 2011-04-15 | Janssen Pharmaceutica N.V. | Kinoliinihendid kasutamiseks latentse tuberkuloosi ravis |
| EE05697B1 (et) | 2005-06-08 | 2014-02-17 | Janssen Pharmaceutica N.V. | Kinoliini derivaadid kui antibakteriaalsed toimeained |
| JO3270B1 (ar) | 2005-06-28 | 2018-09-16 | Janssen Pharmaceutica Nv | مشتقات كوينولين بصفة عوامل مضادة للبكتيريا |
| NZ564340A (en) | 2005-06-28 | 2011-02-25 | Janssen Pharmaceutica Nv | Quinoline derivatives as antibacterial agents |
| JO2752B1 (en) | 2005-06-28 | 2014-03-15 | شركة جانسين فارماسوتيكا ان. في | Quinoline derivatives acting as antibacterial agents |
| JO3077B1 (ar) | 2005-07-28 | 2017-03-15 | Janssen Pharmaceutica Nv | مشتقات كوينولين مضادة للبكتيريا |
| JO2837B1 (en) | 2005-08-03 | 2014-09-15 | جانسن فارمسيتكا ان في | Quinoline derivatives acting as antibacterial agents |
| JO2855B1 (en) | 2005-08-03 | 2015-03-15 | شركة جانسين فارماسوتيكا ان. في | Quinoline derivatives acting as antibacterial agents |
| JO2952B1 (en) | 2005-08-03 | 2016-03-15 | جانسين فارماسوتيكا ان. في | Quinoline derivatives acting as antibacterial agents |
| JO2685B1 (en) | 2006-12-06 | 2013-03-03 | جانسين فارماسوتيكا ان في | Quinoline antibacterial derivatives |
| JO2683B1 (en) | 2006-12-06 | 2013-03-03 | جانسين فارماسوتيكا ان. في | Quinoline antibacterial derivatives |
| JO2684B1 (en) | 2006-12-06 | 2013-03-03 | جانسين فارماسوتيكا ان في | Quinoline antibacterial derivatives |
| JO3271B1 (ar) | 2006-12-06 | 2018-09-16 | Janssen Pharmaceutica Nv | مشتقات الكوينولين المضادة للجراثيم |
| JO2725B1 (en) | 2006-12-06 | 2013-09-15 | جانسين فارماسوتيكا ان. في | Quinoline antibacterial derivatives |
| JO2970B1 (en) | 2006-12-06 | 2016-03-15 | جانسين فارماسوتيكا ان. في | Quinoline antibacterial derivatives |
| US20110059948A1 (en) * | 2008-01-14 | 2011-03-10 | Jyoti Chattopadhyaya | Quinoline, naphthalene and conformationally constrained quinoline or naphthalene derivatives as anti-mycobacterial agents |
| WO2013160431A1 (en) * | 2012-04-27 | 2013-10-31 | Janssen Pharmaceutica Nv | Antibacterial quinoline derivatives |
-
2013
- 2013-04-26 WO PCT/EP2013/058703 patent/WO2013160435A1/en not_active Ceased
- 2013-04-26 IN IN2364MUN2014 patent/IN2014MN02364A/en unknown
- 2013-04-26 JP JP2015507549A patent/JP6153604B2/ja active Active
- 2013-04-26 CN CN201380021790.5A patent/CN104254527B/zh active Active
- 2013-04-26 MX MX2014013056A patent/MX355050B/es active IP Right Grant
- 2013-04-26 KR KR1020147031040A patent/KR102110355B1/ko active Active
- 2013-04-26 DK DK13719524.4T patent/DK2841425T3/en active
- 2013-04-26 US US14/391,045 patent/US9133167B2/en active Active
- 2013-04-26 PL PL13719524.4T patent/PL2841425T3/pl unknown
- 2013-04-26 AU AU2013254674A patent/AU2013254674B2/en not_active Ceased
- 2013-04-26 ES ES13719524.4T patent/ES2576491T3/es active Active
- 2013-04-26 EP EP13719524.4A patent/EP2841425B1/en active Active
- 2013-04-26 CA CA2869718A patent/CA2869718C/en active Active
- 2013-04-26 EA EA201491982A patent/EA035443B1/ru not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2013254674A1 (en) | 2014-10-16 |
| EP2841425A1 (en) | 2015-03-04 |
| US20150065502A1 (en) | 2015-03-05 |
| MX2014013056A (es) | 2014-12-10 |
| KR102110355B1 (ko) | 2020-05-14 |
| EA035443B1 (ru) | 2020-06-17 |
| MX355050B (es) | 2018-04-02 |
| HK1205514A1 (en) | 2015-12-18 |
| KR20150013156A (ko) | 2015-02-04 |
| US9133167B2 (en) | 2015-09-15 |
| IN2014MN02364A (enExample) | 2015-08-14 |
| ES2576491T3 (es) | 2016-07-07 |
| CA2869718C (en) | 2021-05-11 |
| EP2841425B1 (en) | 2016-03-23 |
| CN104254527A (zh) | 2014-12-31 |
| CA2869718A1 (en) | 2013-10-31 |
| JP2015518003A (ja) | 2015-06-25 |
| DK2841425T3 (en) | 2016-06-27 |
| WO2013160435A1 (en) | 2013-10-31 |
| EA201491982A1 (ru) | 2015-02-27 |
| CN104254527B (zh) | 2017-05-31 |
| JP6153604B2 (ja) | 2017-06-28 |
| AU2013254674B2 (en) | 2017-02-02 |
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