PL2841425T3 - Antybakteryjne pochodne chinoliny - Google Patents

Antybakteryjne pochodne chinoliny

Info

Publication number
PL2841425T3
PL2841425T3 PL13719524.4T PL13719524T PL2841425T3 PL 2841425 T3 PL2841425 T3 PL 2841425T3 PL 13719524 T PL13719524 T PL 13719524T PL 2841425 T3 PL2841425 T3 PL 2841425T3
Authority
PL
Poland
Prior art keywords
quinoline derivatives
antibacterial quinoline
antibacterial
derivatives
quinoline
Prior art date
Application number
PL13719524.4T
Other languages
English (en)
Polish (pl)
Inventor
Jerôme Emile Georges Guillemont
Magali Madeleine Simone Motte
David Francis Alain Lançois
Wendy Mia Albert Balemans
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of PL2841425T3 publication Critical patent/PL2841425T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4709Non-condensed quinolines and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/06Antibacterial agents for tuberculosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL13719524.4T 2012-04-27 2013-04-26 Antybakteryjne pochodne chinoliny PL2841425T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP12165934 2012-04-27

Publications (1)

Publication Number Publication Date
PL2841425T3 true PL2841425T3 (pl) 2016-10-31

Family

ID=48227271

Family Applications (1)

Application Number Title Priority Date Filing Date
PL13719524.4T PL2841425T3 (pl) 2012-04-27 2013-04-26 Antybakteryjne pochodne chinoliny

Country Status (14)

Country Link
US (1) US9133167B2 (OSRAM)
EP (1) EP2841425B1 (OSRAM)
JP (1) JP6153604B2 (OSRAM)
KR (1) KR102110355B1 (OSRAM)
CN (1) CN104254527B (OSRAM)
AU (1) AU2013254674B2 (OSRAM)
CA (1) CA2869718C (OSRAM)
DK (1) DK2841425T3 (OSRAM)
EA (1) EA035443B1 (OSRAM)
ES (1) ES2576491T3 (OSRAM)
IN (1) IN2014MN02364A (OSRAM)
MX (1) MX355050B (OSRAM)
PL (1) PL2841425T3 (OSRAM)
WO (1) WO2013160435A1 (OSRAM)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2841426T (pt) * 2012-04-27 2016-11-23 Janssen Pharmaceutica Nv Derivados de quinolina antibacterianos
WO2016020836A1 (en) * 2014-08-06 2016-02-11 Novartis Ag Quinolone derivatives as antibacterials
KR102480410B1 (ko) * 2016-03-07 2022-12-22 더 글로벌 얼라이언스 포 티비 드러그 디벨롭먼트, 잉크. 항박테리아 화합물 및 그의 용도
KR102574912B1 (ko) * 2016-08-17 2023-09-07 덕산네오룩스 주식회사 유기전기 소자용 화합물, 이를 이용한 유기전기소자 및 그 전자 장치
US11857352B2 (en) 2016-09-06 2024-01-02 The Research Foundation For The State University Of New York Positron imaging tomography imaging agent composition and method for bacterial infection
KR102695633B1 (ko) * 2021-12-17 2024-08-14 한국화학연구원 피리미딘을 포함하는 테트라하이드로이소퀴놀린 유도체 및 이의 결핵 치료제 용도
JP2025510646A (ja) 2022-03-14 2025-04-15 スラップ ファーマシューティカルズ エルエルシー 多環式化合物

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2270123A1 (en) 1996-10-28 1998-05-07 Department Of The Army, U.S. Government Compounds, compositions and methods for treating antibiotic-resistant infections
US6103905A (en) 1997-06-19 2000-08-15 Sepracor, Inc. Quinoline-indole antimicrobial agents, uses and compositions related thereto
GB0118238D0 (en) * 2001-07-26 2001-09-19 Smithkline Beecham Plc Medicaments
EA008937B1 (ru) 2002-07-25 2007-10-26 Янссен Фармацевтика Н.В. Производные хинолина и их применение в качестве микобактериальных ингибиторов
CA2553266C (en) * 2004-01-23 2013-03-12 Janssen Pharmaceutica N.V. Substituted quinolines and their use as mycobacterial inhibitors
CN1909907B (zh) 2004-01-23 2010-06-23 詹森药业有限公司 喹啉衍生物及其在制备分枝杆菌抑制剂中的用途
BRPI0507312A (pt) 2004-01-29 2007-06-26 Janssen Pharmaceutica Nv derivados de quinolina para uso como inibidores micobacterianos
RS50585B (sr) 2004-05-28 2010-05-07 Janssen Pharmaceutica N.V. Upotreba supstituisanih kinolinskih derivata za tretman bolesti uzrokovanih mikobakterijama otpornima na lekove
WO2005123081A2 (en) 2004-06-22 2005-12-29 Janssen Pharmaceutica N.V. (2-benzyl-4-{4-[1-(tetrahydrofuran-3-carbonyl)-pyrrolidin-3-yl]-piperazin-1-yl}-piperidin-1-yl)-(3,5-trifluoromethyl-phenyl))-methanone for the treatment of schizophrenia
AU2005288848A1 (en) 2004-09-28 2006-04-06 Janssen Pharmaceutica N.V. A bacterial ATP synthase binding domain
EE05394B1 (et) 2004-12-24 2011-04-15 Janssen Pharmaceutica N.V. Kinoliinihendid kasutamiseks latentse tuberkuloosi ravis
EE05697B1 (et) 2005-06-08 2014-02-17 Janssen Pharmaceutica N.V. Kinoliini derivaadid kui antibakteriaalsed toimeained
HRP20170044T1 (hr) 2005-06-28 2017-03-10 Janssen Pharmaceutica Nv Derivati kinolina kao antibakterijska sredstva
JO3270B1 (ar) 2005-06-28 2018-09-16 Janssen Pharmaceutica Nv مشتقات كوينولين بصفة عوامل مضادة للبكتيريا
JO2752B1 (en) 2005-06-28 2014-03-15 شركة جانسين فارماسوتيكا ان. في Quinoline derivatives acting as antibacterial agents
JO3077B1 (ar) 2005-07-28 2017-03-15 Janssen Pharmaceutica Nv مشتقات كوينولين مضادة للبكتيريا
JO2837B1 (en) 2005-08-03 2014-09-15 جانسن فارمسيتكا ان في Quinoline derivatives acting as antibacterial agents
JO2855B1 (en) 2005-08-03 2015-03-15 شركة جانسين فارماسوتيكا ان. في Quinoline derivatives acting as antibacterial agents
JO2952B1 (en) 2005-08-03 2016-03-15 جانسين فارماسوتيكا ان. في Quinoline derivatives acting as antibacterial agents
JO2684B1 (en) 2006-12-06 2013-03-03 جانسين فارماسوتيكا ان في Quinoline antibacterial derivatives
JO2685B1 (en) 2006-12-06 2013-03-03 جانسين فارماسوتيكا ان في Quinoline antibacterial derivatives
JO2970B1 (en) 2006-12-06 2016-03-15 جانسين فارماسوتيكا ان. في Quinoline antibacterial derivatives
JO2725B1 (en) * 2006-12-06 2013-09-15 جانسين فارماسوتيكا ان. في Quinoline antibacterial derivatives
JO3271B1 (ar) 2006-12-06 2018-09-16 Janssen Pharmaceutica Nv مشتقات الكوينولين المضادة للجراثيم
JO2683B1 (en) 2006-12-06 2013-03-03 جانسين فارماسوتيكا ان. في Quinoline antibacterial derivatives
US20110059948A1 (en) * 2008-01-14 2011-03-10 Jyoti Chattopadhyaya Quinoline, naphthalene and conformationally constrained quinoline or naphthalene derivatives as anti-mycobacterial agents
PT2841426T (pt) * 2012-04-27 2016-11-23 Janssen Pharmaceutica Nv Derivados de quinolina antibacterianos

Also Published As

Publication number Publication date
JP6153604B2 (ja) 2017-06-28
EP2841425B1 (en) 2016-03-23
JP2015518003A (ja) 2015-06-25
MX2014013056A (es) 2014-12-10
AU2013254674B2 (en) 2017-02-02
IN2014MN02364A (OSRAM) 2015-08-14
ES2576491T3 (es) 2016-07-07
EA035443B1 (ru) 2020-06-17
EA201491982A1 (ru) 2015-02-27
CA2869718C (en) 2021-05-11
WO2013160435A1 (en) 2013-10-31
KR102110355B1 (ko) 2020-05-14
DK2841425T3 (en) 2016-06-27
KR20150013156A (ko) 2015-02-04
AU2013254674A1 (en) 2014-10-16
US9133167B2 (en) 2015-09-15
EP2841425A1 (en) 2015-03-04
CN104254527A (zh) 2014-12-31
US20150065502A1 (en) 2015-03-05
CA2869718A1 (en) 2013-10-31
MX355050B (es) 2018-04-02
HK1205514A1 (en) 2015-12-18
CN104254527B (zh) 2017-05-31

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