PL2768807T3 - Sposoby wytwarzania 6-chloro-2,3,4,9-tetrahydro-1H-karbazolo-1-karboksyamidu oraz jego prekursorów - Google Patents
Sposoby wytwarzania 6-chloro-2,3,4,9-tetrahydro-1H-karbazolo-1-karboksyamidu oraz jego prekursorówInfo
- Publication number
- PL2768807T3 PL2768807T3 PL12783161T PL12783161T PL2768807T3 PL 2768807 T3 PL2768807 T3 PL 2768807T3 PL 12783161 T PL12783161 T PL 12783161T PL 12783161 T PL12783161 T PL 12783161T PL 2768807 T3 PL2768807 T3 PL 2768807T3
- Authority
- PL
- Poland
- Prior art keywords
- carbazole
- carboxamide
- tetrahydro
- precursors
- chloro
- Prior art date
Links
- FUZYTVDVLBBXDL-UHFFFAOYSA-N 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide Chemical compound N1C2=CC=C(Cl)C=C2C2=C1C(C(=O)N)CCC2 FUZYTVDVLBBXDL-UHFFFAOYSA-N 0.000 title 1
- 239000002243 precursor Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11185959 | 2011-10-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2768807T3 true PL2768807T3 (pl) | 2017-03-31 |
Family
ID=47143859
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL12783161T PL2768807T3 (pl) | 2011-10-20 | 2012-10-19 | Sposoby wytwarzania 6-chloro-2,3,4,9-tetrahydro-1H-karbazolo-1-karboksyamidu oraz jego prekursorów |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US20140303382A1 (pl) |
| EP (1) | EP2768807B1 (pl) |
| JP (1) | JP6142459B2 (pl) |
| CN (1) | CN103958467B (pl) |
| AR (1) | AR088377A1 (pl) |
| AU (1) | AU2012324824B2 (pl) |
| BR (1) | BR112014009297A2 (pl) |
| CA (1) | CA2852797C (pl) |
| ES (1) | ES2585077T3 (pl) |
| HR (1) | HRP20160918T1 (pl) |
| HU (1) | HUE029282T2 (pl) |
| IL (1) | IL232058A (pl) |
| PL (1) | PL2768807T3 (pl) |
| PT (1) | PT2768807T (pl) |
| SI (1) | SI2768807T1 (pl) |
| WO (1) | WO2013057258A1 (pl) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3248174B2 (ja) | 1992-10-02 | 2002-01-21 | 日本電信電話株式会社 | 光通信方式 |
| JP3252303B2 (ja) | 1993-03-11 | 2002-02-04 | 日本電信電話株式会社 | 光通信方式 |
| GB201312768D0 (en) * | 2013-07-17 | 2013-08-28 | Ge Healthcare Ltd | Work-up procedure |
| TW202515536A (zh) | 2023-05-16 | 2025-04-16 | 列支敦斯登商Ａｏｐ孤兒藥智慧財產股份有限公司 | 以解析方法來製備富含鏡像異構型態的（ｓ）－６－氯－２，３，４，９－四氫－１ｈ－咔唑－甲醯胺 |
| AU2024273952A1 (en) | 2023-05-16 | 2025-11-06 | Aop Orphan Ip Ag | New polymorphs of (s)-6-chloro-2,3,4,9-tetrahydro-1h-carbazole-1-carboxamide in crystalline form |
| CN120118019A (zh) * | 2023-12-08 | 2025-06-10 | 苏州湃芮生物科技有限公司 | 一种RNA m6A调控剂的共晶形式及其制备方法与应用 |
| CN120136769A (zh) * | 2023-12-11 | 2025-06-13 | 苏州湃芮生物科技有限公司 | 一种RNA m6A调控剂的结晶形式及其制备方法与应用 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3769298A (en) * | 1971-04-02 | 1973-10-30 | Pfizer | Substituted aminomethylcarbazoles |
| DE2431292A1 (de) * | 1974-06-27 | 1976-01-15 | Schering Ag | Neue carbazol-derivate |
| DE2337154C2 (de) * | 1973-07-18 | 1986-04-24 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue Carbazolderivate |
| US4057640A (en) * | 1973-07-18 | 1977-11-08 | Schering Aktiengesellschaft | 5,6,7,8:Tetrahydrocarbazole-1-carboxylic acid derivatives |
| BG25793A3 (bg) * | 1973-07-18 | 1978-12-12 | Schering Aktiengesellschaft | Метод за получаване на карбазолови деривати |
| US3907054A (en) | 1974-06-13 | 1975-09-23 | Caterpillar Tractor Co | Diagonal brace bearing for crawler-type tractors |
| GB1504707A (en) | 1974-08-07 | 1978-03-22 | Bellon Labor Sa Roger | 1-aryl-2-oxo-2,4,5,6,7,7a-hexahydroindoles |
| DZ2770A1 (fr) | 1998-04-17 | 2003-12-01 | Lilly Co Eli | Procédé de préparation de 1h-indol-3 glyoxamides substituées en position 4. |
| DZ2769A1 (fr) | 1998-04-17 | 2003-12-01 | Lilly Co Eli | Composés tricycliques substitués. |
| AR038136A1 (es) * | 2002-01-24 | 2004-12-29 | Merck Frosst Canada Inc | Cicloalcanindoles con sustitucion con fluor composiciones que contienen estos compuestos y metodos de tratamiento |
| WO2004063155A1 (en) | 2003-01-06 | 2004-07-29 | Eli Lilly And Company | Fused heterocyclic derivatives as ppar modulators |
| FR2849811B1 (fr) | 2003-01-10 | 2006-01-21 | Renault Sas | Systeme de controle longitudinal pour le maintien a l'arret d'un vehicule equipe d'une boite de vitesses automatique |
| US20060074124A1 (en) * | 2003-09-12 | 2006-04-06 | Andrew Napper | Methods of treating a disorder |
| EP1677794B1 (en) * | 2003-09-12 | 2014-12-03 | Elixir Pharmaceuticals, Inc. | Methods of treating disorder |
| US7534264B2 (en) * | 2004-01-28 | 2009-05-19 | Ultradent Products, Inc. | Delivery system for bone growth promoting material |
| US20050256181A1 (en) * | 2004-01-29 | 2005-11-17 | Elixir Pharmaceuticals, Inc. | Treating a viral disorder |
| US7104702B2 (en) | 2004-03-24 | 2006-09-12 | Corning Cable Systems Llc | Field installable optical fiber connector |
| US20060003065A1 (en) | 2004-07-01 | 2006-01-05 | Kateman Paul R | Dry-base aerated food product dispensing method and apparatus |
| EP1824821A2 (en) * | 2004-11-23 | 2007-08-29 | PTC Therapeutics, Inc. | Carbazole, carboline and indole derivatives useful in the inhibition of vegf production |
| TW200640931A (en) * | 2005-02-17 | 2006-12-01 | Wyeth Corp | Cycloalkylfused indole, benzothiophene, benzofuran and indene derivatives |
| WO2006099245A1 (en) * | 2005-03-11 | 2006-09-21 | Elixir Pharmaceuticals, Inc. | Sirt inhibitors that bind to nad |
| WO2007047604A2 (en) * | 2005-10-18 | 2007-04-26 | Elixir Pharmaceuticals, Inc. | Sirt1 inhibition |
| DE102006029320B3 (de) * | 2006-06-23 | 2007-10-11 | Röhm Gmbh | Verfahren zur kontinuierlichen Herstellung von ungesättigten Carbonsäureanhydriden |
| WO2008019825A1 (en) * | 2006-08-14 | 2008-02-21 | Santhera Pharmaceuticals (Schweiz) Ag | Use of tricyclic indole derivatives for the treatment of muscular diseases |
-
2012
- 2012-10-18 AR ARP120103882A patent/AR088377A1/es active IP Right Grant
- 2012-10-19 HR HRP20160918TT patent/HRP20160918T1/hr unknown
- 2012-10-19 BR BR112014009297A patent/BR112014009297A2/pt not_active Application Discontinuation
- 2012-10-19 CN CN201280050969.9A patent/CN103958467B/zh active Active
- 2012-10-19 CA CA2852797A patent/CA2852797C/en active Active
- 2012-10-19 PT PT127831618T patent/PT2768807T/pt unknown
- 2012-10-19 PL PL12783161T patent/PL2768807T3/pl unknown
- 2012-10-19 JP JP2014536256A patent/JP6142459B2/ja active Active
- 2012-10-19 AU AU2012324824A patent/AU2012324824B2/en active Active
- 2012-10-19 US US14/352,623 patent/US20140303382A1/en not_active Abandoned
- 2012-10-19 SI SI201230655A patent/SI2768807T1/sl unknown
- 2012-10-19 EP EP12783161.8A patent/EP2768807B1/en active Active
- 2012-10-19 HU HUE12783161A patent/HUE029282T2/en unknown
- 2012-10-19 WO PCT/EP2012/070769 patent/WO2013057258A1/en not_active Ceased
- 2012-10-19 ES ES12783161.8T patent/ES2585077T3/es active Active
-
2014
- 2014-04-10 IL IL232058A patent/IL232058A/en active IP Right Grant
-
2016
- 2016-04-20 US US15/134,028 patent/US10329254B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| HUE029282T2 (en) | 2017-02-28 |
| EP2768807A1 (en) | 2014-08-27 |
| US20140303382A1 (en) | 2014-10-09 |
| AU2012324824B2 (en) | 2016-08-11 |
| BR112014009297A2 (pt) | 2017-04-11 |
| CA2852797C (en) | 2020-02-04 |
| AU2012324824A1 (en) | 2014-05-08 |
| CN103958467B (zh) | 2016-10-12 |
| CN103958467A (zh) | 2014-07-30 |
| PT2768807T (pt) | 2016-08-08 |
| ES2585077T3 (es) | 2016-10-03 |
| IL232058A0 (en) | 2014-05-28 |
| HK1200452A1 (en) | 2015-08-07 |
| AR088377A1 (es) | 2014-05-28 |
| JP2014530839A (ja) | 2014-11-20 |
| HRP20160918T1 (hr) | 2016-09-23 |
| IL232058A (en) | 2016-02-29 |
| WO2013057258A1 (en) | 2013-04-25 |
| US20160304455A1 (en) | 2016-10-20 |
| JP6142459B2 (ja) | 2017-06-07 |
| US10329254B2 (en) | 2019-06-25 |
| SI2768807T1 (sl) | 2016-09-30 |
| EP2768807B1 (en) | 2016-05-04 |
| CA2852797A1 (en) | 2013-04-25 |
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