PL2766040T3 - Pertuzumab, trastuzumab, docetaksel i karboplatyna w leczeniu wczesnego stadium raka piersi - Google Patents
Pertuzumab, trastuzumab, docetaksel i karboplatyna w leczeniu wczesnego stadium raka piersiInfo
- Publication number
- PL2766040T3 PL2766040T3 PL12778010T PL12778010T PL2766040T3 PL 2766040 T3 PL2766040 T3 PL 2766040T3 PL 12778010 T PL12778010 T PL 12778010T PL 12778010 T PL12778010 T PL 12778010T PL 2766040 T3 PL2766040 T3 PL 2766040T3
- Authority
- PL
- Poland
- Prior art keywords
- pertuzumab
- trastuzumab
- docetaxel
- carboplatin
- treatment
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A61K2039/507—Comprising a combination of two or more separate antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Packages (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161547535P | 2011-10-14 | 2011-10-14 | |
| US201161567015P | 2011-12-05 | 2011-12-05 | |
| US201261657669P | 2012-06-08 | 2012-06-08 | |
| US201261682037P | 2012-08-10 | 2012-08-10 | |
| US201261694584P | 2012-08-29 | 2012-08-29 | |
| EP12778010.4A EP2766040B1 (en) | 2011-10-14 | 2012-10-11 | Pertuzumab, trastuzumab, docetaxel and carboplatin for the treatment of early-stage breast cancer |
| PCT/US2012/059683 WO2013055874A2 (en) | 2011-10-14 | 2012-10-11 | Uses for and article of manufacture including her2 dimerization inhibitor pertuzumab |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2766040T3 true PL2766040T3 (pl) | 2019-11-29 |
Family
ID=47073543
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL24174637.9T PL4403228T3 (pl) | 2011-10-14 | 2012-10-11 | Zastosowania i wyrób przemysłowy zawierający pertuzumab, inhibitor dimeryzacji HER2 |
| PL12778010T PL2766040T3 (pl) | 2011-10-14 | 2012-10-11 | Pertuzumab, trastuzumab, docetaksel i karboplatyna w leczeniu wczesnego stadium raka piersi |
| PL23172847.8T PL4241849T3 (pl) | 2011-10-14 | 2012-10-11 | Zastosowania i wyrób przemysłowy zawierający pertuzumab, inhibitor dimeryzacji HER2 |
| PL23172794.2T PL4234033T3 (pl) | 2011-10-14 | 2012-10-11 | Zastosowania i wyrób przemysłowy zawierający pertuzumab, inhibitor dimeryzacji HER2 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL24174637.9T PL4403228T3 (pl) | 2011-10-14 | 2012-10-11 | Zastosowania i wyrób przemysłowy zawierający pertuzumab, inhibitor dimeryzacji HER2 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL23172847.8T PL4241849T3 (pl) | 2011-10-14 | 2012-10-11 | Zastosowania i wyrób przemysłowy zawierający pertuzumab, inhibitor dimeryzacji HER2 |
| PL23172794.2T PL4234033T3 (pl) | 2011-10-14 | 2012-10-11 | Zastosowania i wyrób przemysłowy zawierający pertuzumab, inhibitor dimeryzacji HER2 |
Country Status (30)
| Country | Link |
|---|---|
| US (9) | US20130095172A1 (pl) |
| EP (7) | EP3598981A3 (pl) |
| JP (9) | JP2014530235A (pl) |
| KR (5) | KR20240109285A (pl) |
| CN (8) | CN109908341B (pl) |
| AU (4) | AU2012322797B2 (pl) |
| BR (1) | BR112014007521A8 (pl) |
| CL (1) | CL2014000889A1 (pl) |
| DK (4) | DK4234033T3 (pl) |
| EA (1) | EA034390B1 (pl) |
| ES (4) | ES3023516T3 (pl) |
| FI (3) | FI4241849T3 (pl) |
| HK (1) | HK1202242A1 (pl) |
| HR (1) | HRP20191247T1 (pl) |
| HU (1) | HUE044352T2 (pl) |
| IL (5) | IL309917A (pl) |
| IN (1) | IN2014CN02703A (pl) |
| LT (4) | LT4241849T (pl) |
| MX (2) | MX2014004021A (pl) |
| MY (2) | MY194408A (pl) |
| PE (1) | PE20142363A1 (pl) |
| PH (2) | PH12014500733B1 (pl) |
| PL (4) | PL4403228T3 (pl) |
| PT (4) | PT4241849T (pl) |
| RS (1) | RS58944B1 (pl) |
| SG (3) | SG11201401432XA (pl) |
| SI (4) | SI4403228T1 (pl) |
| UA (2) | UA123092C2 (pl) |
| WO (1) | WO2013055874A2 (pl) |
| ZA (1) | ZA201401259B (pl) |
Families Citing this family (37)
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| JO3000B1 (ar) | 2004-10-20 | 2016-09-05 | Genentech Inc | مركبات أجسام مضادة . |
| DK1850874T3 (da) | 2005-02-23 | 2013-11-11 | Genentech Inc | Forlængelse af tid til sygdomsprogression eller overlevelse for ovariecancer ved anvendelse af pertuzumab |
| BRPI0808418A2 (pt) | 2007-03-02 | 2014-07-22 | Genentech, Inc | Predição de resposta a um inibidor de her |
| US9901567B2 (en) | 2007-08-01 | 2018-02-27 | Syntarga B.V. | Substituted CC-1065 analogs and their conjugates |
| TWI472339B (zh) | 2008-01-30 | 2015-02-11 | Genentech Inc | 包含結合至her2結構域ii之抗體及其酸性變異體的組合物 |
| BRPI0812682A2 (pt) | 2008-06-16 | 2010-06-22 | Genentech Inc | tratamento de cáncer de mama metastático |
| CA2742568C (en) | 2008-11-03 | 2017-09-26 | Syntarga B.V. | Novel cc-1065 analogs and their conjugates |
| US9345661B2 (en) | 2009-07-31 | 2016-05-24 | Genentech, Inc. | Subcutaneous anti-HER2 antibody formulations and uses thereof |
| EP3108886B1 (en) | 2010-04-21 | 2020-06-17 | Syntarga B.V. | Conjugates of cc-1065 analogs and bifunctional linkers |
| MY194408A (en) | 2011-10-14 | 2022-11-30 | Genentech Inc | Uses for and Article of Manufacture Including Her2 Dimerization Inhibitor Pertuzumab |
| US9180185B2 (en) | 2013-01-11 | 2015-11-10 | Hoffman-La Roche Inc. | Combination therapy of anti-HER3 antibodies |
| TWI554284B (zh) | 2013-04-16 | 2016-10-21 | 建南德克公司 | 帕妥珠單抗(pertuzumab)變體及其評估 |
| BR112015031903A8 (pt) * | 2013-06-19 | 2019-12-31 | Seragon Pharmaceuticals Inc | composto, sal farmaceuticamente aceitável, composição farmacêutica e uso de um composto |
| NZ760065A (en) | 2013-12-17 | 2022-12-23 | Genentech Inc | Methods of treating cancers using pd-1 axis binding antagonists and taxanes |
| CN104726462A (zh) * | 2013-12-20 | 2015-06-24 | 北京天广实生物技术股份有限公司 | 抗her2人源化抗体mil41、其制备方法及用途 |
| TR201810856T4 (tr) | 2014-01-10 | 2018-08-27 | Synthon Biopharmaceuticals Bv | CYS'le bağlı antikor-ilaç konjugatlarını saflaştırmak için usul. |
| RU2686085C2 (ru) * | 2014-01-10 | 2019-04-24 | Синтон Байофармасьютикалс Б. В. | Конъюгаты антитело-лекарственное средство (adc) с дуокармицином, применяемые для лечения рака эндометрия |
| JP6342517B2 (ja) * | 2014-01-10 | 2018-06-13 | シントン・バイオファーマシューティカルズ・ビー.ブイ.Synthon Biopharmaceuticals B.V. | 改善されたインビボ抗腫瘍活性を示すデュオカルマイシンadc |
| WO2016094341A1 (en) * | 2014-12-08 | 2016-06-16 | Synta Pharmaceuticals Corp. | Triple combination therapy, comprising ganetespib, a taxane and an antibody, for use in the treatment of her2 positive breast cancer |
| AU2016270686B2 (en) * | 2015-05-29 | 2019-12-19 | Expression Pathology, Inc. | Quantifying Her2 protein for optimal cancer therapy |
| IL256080B2 (en) | 2015-06-17 | 2025-06-01 | Genentech Inc | Methods of treating locally advanced or metastatic breast cancers using pd-1 axis binding antagonists and taxanes |
| EP3313890A1 (en) | 2015-06-24 | 2018-05-02 | H. Hoffnabb-La Roche Ag | Trispecific antibodies specific for her2 and a blood brain barrier receptor and methods of use |
| KR20220157515A (ko) * | 2016-03-15 | 2022-11-29 | 씨젠 인크. | Liv1-adc와 화학요법제를 사용한 병용 요법 |
| WO2018085513A1 (en) * | 2016-11-04 | 2018-05-11 | Genentech, Inc. | Treatment of her2-positive breast cancer |
| JP6914336B2 (ja) * | 2016-12-28 | 2021-08-04 | ジェネンテック, インコーポレイテッド | 進行したher2発現がんの治療 |
| CN117752782A (zh) * | 2017-01-17 | 2024-03-26 | 豪夫迈·罗氏有限公司 | 皮下her2抗体配制剂 |
| CN116531511A (zh) * | 2017-03-02 | 2023-08-04 | 豪夫迈·罗氏有限公司 | Her2阳性乳腺癌的辅助治疗 |
| KR102267593B1 (ko) * | 2018-10-19 | 2021-06-21 | 주식회사 프로티나 | Her2 및 her3의 헤테로다이머를 표적으로 하는 약물 및 이의 스크리닝 방법 |
| WO2020150702A1 (en) * | 2019-01-18 | 2020-07-23 | University Of Southern California | Methods and compositions to improve the safety and efficacy of cellular therapies |
| EA202193257A1 (ru) * | 2019-05-27 | 2022-03-10 | Толмар Интернэшнл Лимитед | Композиции ацетата лейпролида и способы их применения для лечения рака молочной железы |
| AU2020303572A1 (en) | 2019-06-28 | 2022-01-20 | Board Of Regents, The University Of Texas System | Preparation of preliposomal Annamycin lyophilizate |
| MX2021015667A (es) * | 2019-06-28 | 2022-04-18 | Univ Texas | Metodo de reconstitucion de anamicina liposomica. |
| AU2020381495A1 (en) * | 2019-11-15 | 2022-05-19 | Seagen Inc. | Methods of treating HER2 positive breast cancer with tucatinib in combination with an anti-HER2 antibody-drug conjugate |
| WO2021222068A1 (en) * | 2020-04-29 | 2021-11-04 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Compositions and methods for detecting gene fusions of esr1 and ccdc170 for determining increased resistance to endocrine therapy and for cancer treatment |
| CN111710425A (zh) * | 2020-06-19 | 2020-09-25 | 复旦大学附属中山医院 | 一种免疫检查点抑制剂心脏毒性评估方法,系统及装置 |
| KR20250151568A (ko) * | 2020-06-29 | 2025-10-21 | 제넨테크, 인크. | 퍼투주맙 + 트라스투주맙 고정 용량 조합 |
| KR20240119103A (ko) * | 2021-12-07 | 2024-08-06 | 아이오 테라퓨틱스, 인크. | Her2+ 암 치료에서의 rxr 작용제 및 탁산의 용도 |
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