PL2643344T3 - Peptyd pochodzący z ludzkiej laktoferyny do zastosowania jako środek maskujący antygen - Google Patents

Peptyd pochodzący z ludzkiej laktoferyny do zastosowania jako środek maskujący antygen

Info

Publication number
PL2643344T3
PL2643344T3 PL10784307T PL10784307T PL2643344T3 PL 2643344 T3 PL2643344 T3 PL 2643344T3 PL 10784307 T PL10784307 T PL 10784307T PL 10784307 T PL10784307 T PL 10784307T PL 2643344 T3 PL2643344 T3 PL 2643344T3
Authority
PL
Poland
Prior art keywords
masking agent
derived peptide
human lactoferrin
lactoferrin derived
antigen masking
Prior art date
Application number
PL10784307T
Other languages
English (en)
Inventor
Benedikt Hartwig
Alcalde Juan Tome
Norbert Windhab
PANZANO María del Pilar ANSUATEGUI
CARRERA Matías Javier VARA
Original Assignee
Evonik Röhm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evonik Röhm Gmbh filed Critical Evonik Röhm Gmbh
Publication of PL2643344T3 publication Critical patent/PL2643344T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/644Transferrin, e.g. a lactoferrin or ovotransferrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6811Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/79Transferrins, e.g. lactoferrins, ovotransferrins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/40Transferrins, e.g. lactoferrins, ovotransferrins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
PL10784307T 2010-11-26 2010-11-26 Peptyd pochodzący z ludzkiej laktoferyny do zastosowania jako środek maskujący antygen PL2643344T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/EP2010/068302 WO2012069089A1 (en) 2010-11-26 2010-11-26 Human lactoferrin derived peptide for use as an antigen masking agent
EP10784307.0A EP2643344B1 (en) 2010-11-26 2010-11-26 Human lactoferrin derived peptide for use as an antigen masking agent

Publications (1)

Publication Number Publication Date
PL2643344T3 true PL2643344T3 (pl) 2017-09-29

Family

ID=43837881

Family Applications (1)

Application Number Title Priority Date Filing Date
PL10784307T PL2643344T3 (pl) 2010-11-26 2010-11-26 Peptyd pochodzący z ludzkiej laktoferyny do zastosowania jako środek maskujący antygen

Country Status (17)

Country Link
US (1) US9724422B2 (pl)
EP (1) EP2643344B1 (pl)
JP (1) JP6073239B2 (pl)
KR (1) KR101765364B1 (pl)
CN (1) CN103906760B (pl)
AU (1) AU2010364538B2 (pl)
BR (1) BR112013012811B8 (pl)
CA (1) CA2818951C (pl)
ES (1) ES2627960T3 (pl)
HK (1) HK1196379A1 (pl)
HU (1) HUE033501T2 (pl)
IL (1) IL226198B (pl)
MX (1) MX348337B (pl)
PL (1) PL2643344T3 (pl)
RU (1) RU2573422C2 (pl)
SI (1) SI2643344T1 (pl)
WO (1) WO2012069089A1 (pl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2767501T3 (es) 2014-05-28 2020-06-17 Evonik Operations Gmbh Nanopartícula
JP2019508036A (ja) 2016-02-16 2019-03-28 ダナ−ファーバー キャンサー インスティテュート,インコーポレイテッド 免疫療法組成物及び方法
DE102016008601B4 (de) 2016-07-14 2019-05-23 Giesecke+Devrient Currency Technology Gmbh Sicherheitselement mit reversibel veränderbarem Farbbereich
US11021529B2 (en) 2017-03-03 2021-06-01 Massachusetts Institute Of Technology Antimicrobial constructs and uses thereof
CN107226860B (zh) * 2017-07-06 2020-04-10 浙江辉肽生命健康科技有限公司 一种生物活性多肽skhssldcvl及其制备方法和应用
JP2021523137A (ja) 2018-05-08 2021-09-02 エボニック オペレーションズ ゲーエムベーハー 生体吸収性ポリエステル、親水性ポリマーおよびアシル化ヒトラクトフェリン由来ペプチドを含むナノ粒子

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6066469A (en) * 1990-03-08 2000-05-23 Ferro Dynamics, Inc. Cloning, expression, and uses of human lactoferrin
US5977337A (en) 1997-06-03 1999-11-02 Connaught Laboratories Limited Lactoferrin receptor genes of Moraxella
JP3681982B2 (ja) 1998-07-15 2005-08-10 サムヤン ジェネックス コーポレイション 酵母からラクトフェリンポリペプチドを大量生産する方法及びそれに有用な微生物菌株
JP2000045182A (ja) 1998-07-23 2000-02-15 Peptide Science:Kk 抗菌性繊維および繊維・皮革用抗菌加工剤
US20070259007A1 (en) * 1999-10-19 2007-11-08 Kruzel Marian L Lactoferrin: an adjuvant for vaccines
RU2165769C1 (ru) 2000-07-13 2001-04-27 Якубовская Раиса Ивановна Антибактериальный, антиоксидантный, иммуномодулирующий и антиканцерогенный препарат и способ его применения
ATE395596T1 (de) 2002-10-25 2008-05-15 Techlab Inc Diagnostisches panel ibd-first chek fur entzundliche darmerkrankung (ibd) und reizkolon
WO2004052305A2 (en) 2002-12-10 2004-06-24 Agennix Incorporated Lactoferrin as an agent in the prevention of organ transplant rejection and graft-versus-host-disease
DE102005051366A1 (de) 2005-10-25 2007-04-26 Degussa Gmbh Drug Delivery Systeme
CN101395180B (zh) * 2005-12-30 2016-06-22 赢创罗姆有限责任公司 用作细胞穿膜肽的肽

Also Published As

Publication number Publication date
KR101765364B1 (ko) 2017-08-08
CA2818951C (en) 2018-03-13
WO2012069089A1 (en) 2012-05-31
BR112013012811A2 (pt) 2016-09-13
JP2014501723A (ja) 2014-01-23
RU2573422C2 (ru) 2016-01-20
BR112013012811B8 (pt) 2022-07-05
EP2643344B1 (en) 2017-03-22
AU2010364538A1 (en) 2013-07-11
US20130302342A1 (en) 2013-11-14
CN103906760B (zh) 2017-02-22
HK1196379A1 (zh) 2014-12-12
SI2643344T1 (sl) 2017-07-31
ES2627960T3 (es) 2017-08-01
KR20130119955A (ko) 2013-11-01
HUE033501T2 (en) 2017-12-28
IL226198A0 (en) 2013-07-31
EP2643344A1 (en) 2013-10-02
US9724422B2 (en) 2017-08-08
BR112013012811B1 (pt) 2021-07-06
CA2818951A1 (en) 2012-05-31
JP6073239B2 (ja) 2017-02-01
MX2013005820A (es) 2013-07-12
MX348337B (es) 2017-06-07
RU2013128884A (ru) 2015-01-10
AU2010364538B2 (en) 2016-04-14
CN103906760A (zh) 2014-07-02
IL226198B (en) 2019-01-31

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