PL2409963T3 - Zastosowanie pochodnych wielonienasyconych kwasów tłuszczowych jako leki - Google Patents

Zastosowanie pochodnych wielonienasyconych kwasów tłuszczowych jako leki

Info

Publication number
PL2409963T3
PL2409963T3 PL10753158T PL10753158T PL2409963T3 PL 2409963 T3 PL2409963 T3 PL 2409963T3 PL 10753158 T PL10753158 T PL 10753158T PL 10753158 T PL10753158 T PL 10753158T PL 2409963 T3 PL2409963 T3 PL 2409963T3
Authority
PL
Poland
Prior art keywords
medicaments
derivatives
fatty acids
polyunsaturated fatty
polyunsaturated
Prior art date
Application number
PL10753158T
Other languages
English (en)
Inventor
Ruiz Pablo Vicente Escribá
Xaubet Xavier Busquets
Jiménez Silvia Terés
Coblijn Gwendolyn Barceló
Cañellas Victoria Lladó
Etxenike Amaia Marcilla
María Laura Martín
Urbano Mónica Higuera
Martínez Rafael Álvarez
Daniel Horacio López
Original Assignee
Lipopharma Therapeutics, S.L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lipopharma Therapeutics, S.L filed Critical Lipopharma Therapeutics, S.L
Publication of PL2409963T3 publication Critical patent/PL2409963T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/42Unsaturated compounds containing hydroxy or O-metal groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/201Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/661Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Emergency Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL10753158T 2009-03-16 2010-03-15 Zastosowanie pochodnych wielonienasyconych kwasów tłuszczowych jako leki PL2409963T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200900725A ES2345241B1 (es) 2009-03-16 2009-03-16 Uso de 2-hidroxiderivados de acidos grasos poliinsaturados como medicamentos.
EP10753158.4A EP2409963B1 (en) 2009-03-16 2010-03-15 Use of derivatives of polyunsaturated fatty acids as medicaments

Publications (1)

Publication Number Publication Date
PL2409963T3 true PL2409963T3 (pl) 2017-05-31

Family

ID=42673244

Family Applications (1)

Application Number Title Priority Date Filing Date
PL10753158T PL2409963T3 (pl) 2009-03-16 2010-03-15 Zastosowanie pochodnych wielonienasyconych kwasów tłuszczowych jako leki

Country Status (19)

Country Link
US (7) US9161928B2 (pl)
EP (2) EP3159329B1 (pl)
JP (1) JP5904592B2 (pl)
KR (4) KR20180021931A (pl)
CN (4) CN106420686B (pl)
AU (6) AU2010224749B2 (pl)
BR (1) BRPI1009860A8 (pl)
CA (1) CA2754963C (pl)
CL (1) CL2011002268A1 (pl)
DK (2) DK3159329T3 (pl)
ES (3) ES2345241B1 (pl)
HK (1) HK1232207A1 (pl)
HU (2) HUE032027T2 (pl)
MX (1) MX2011009614A (pl)
PL (1) PL2409963T3 (pl)
PT (2) PT2409963T (pl)
RU (1) RU2513995C2 (pl)
SI (1) SI3159329T1 (pl)
WO (1) WO2010106211A1 (pl)

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ES2345241B1 (es) 2009-03-16 2011-09-08 Lipopharma Therapeutics Uso de 2-hidroxiderivados de acidos grasos poliinsaturados como medicamentos.
WO2011053870A1 (en) 2009-10-30 2011-05-05 Retrotope, Inc. Alleviating oxidative stress disorders with pufa derivatives
WO2012148930A2 (en) 2011-04-26 2012-11-01 Retrotope, Inc. Oxidative retinal diseases
KR102111997B1 (ko) 2011-04-26 2020-05-18 레트로토프 인코포레이티드 Pufa와 관련된 신경퇴행성 질환 및 근육 질환
US10154978B2 (en) 2011-04-26 2018-12-18 Retrotope, Inc. Disorders implicating PUFA oxidation
KR102020579B1 (ko) 2011-04-26 2019-09-10 레트로토프 인코포레이티드 에너지 프로세싱 손상 장애 및 미토콘드리아 결함
ES2401629B1 (es) * 2011-10-07 2014-03-04 Universitat De Les Illes Balears Enantiómeros de 2-hidroxiderivados de ácidos grasos y su uso como medicamentos.
WO2016062746A1 (en) * 2014-10-21 2016-04-28 Universitat De Les Illes Balears Method for the synthesis of hydroxy-triglycerides and uses thereof for the prevention and treatment of diseases
US20180024150A1 (en) * 2015-03-06 2018-01-25 Niigata University Biomarker of dementia with lewy bodies
JP7048976B2 (ja) 2015-11-23 2022-04-06 レトロトップ、 インコーポレイテッド 1,4-ジエン系の部位特異的同位体標識
GB201521085D0 (en) * 2015-11-30 2016-01-13 Biozep As Use
BR112019023944A2 (pt) 2017-05-16 2020-06-09 Ability Pharmaceuticals S L combinação farmacêutica para o tratamento de um câncer
US10596165B2 (en) 2018-02-12 2020-03-24 resTORbio, Inc. Combination therapies
SG11202012447YA (en) 2018-06-15 2021-01-28 Navitor Pharm Inc Rapamycin analogs and uses thereof
IL293549A (en) 2019-12-05 2022-08-01 Anakuria Therapeutics Inc Rapamycin analogs and their uses
ES2846824B2 (es) * 2020-01-29 2022-01-19 Univ Illes Balears Profarmacos de acidos grasos poliinsaturados y usos medicos de los mismos
EP4098649A4 (en) * 2020-01-29 2024-04-17 Universitat de les Illes Balears METABOLITES OF ALPHA-HYDROXYLATED FATTY ACIDS, THEIR MEDICAL USES AND THEIR USE AS BIOMARKERS
CN114980879A (zh) 2020-02-10 2022-08-30 能力制药公司 用于治疗癌症的药物组合
EP4107163A4 (en) 2020-02-21 2024-06-19 Retrotope, Inc. PROCESS FOR ISOTOPIC MODIFICATION OF POLYUNSATURATED FATTY ACIDS AND THEIR DERIVATIVES

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GB2218984B (en) * 1988-05-27 1992-09-23 Renafield Limited Process for preparing high-concentration mixtures of polyunsaturated fatty acids & their esters and their prophylactic or therapeutic uses
JPH05974A (ja) * 1991-06-21 1993-01-08 Sagami Chem Res Center ハロゲン化不飽和アルキル化合物及びその前駆体
ES2161146B1 (es) * 1999-06-29 2002-07-01 Consejo Superior Investigacion Compuestos antimicrobianos, uso y metodo para inducir resistencia a infecciones de bacterias en plantas.
US6344574B1 (en) 2000-07-20 2002-02-05 The United States Of America As Represented By The Secretary Of Agriculture Solvent fractionation of chicken fat for making lipid compositions enriched in unsaturated fatty acid-containing triacylglycerols
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ES2186576B1 (es) * 2001-10-11 2004-09-16 Universitat De Les Illes Balears Acido 2-hidroxioleico para utilizar como medicamento.
ES2527753T3 (es) * 2002-04-01 2015-01-29 University Of Southern California Eicosanoides trihidroxi poliinsaturados
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US7550613B2 (en) * 2005-05-04 2009-06-23 Pronova Biopharma Norge As Compounds
CN101213281B (zh) * 2005-05-04 2013-03-13 普罗诺瓦生物医药挪威公司 新的dha衍生物及其作为药物的用途
US8059805B2 (en) * 2005-06-30 2011-11-15 Emc Corporation Enhanced services provided using communication redirection and processing
CA2614473C (en) 2005-07-08 2016-05-03 Martek Biosciences Corporation Polyunsaturated fatty acids for treatment of dementia and pre-dementia-related conditions
EP1772146A1 (en) 2005-10-03 2007-04-11 Neuropharma, S.A. Polyunsaturated fatty acids as bace inhibitors
WO2007058523A1 (en) * 2005-11-17 2007-05-24 N.V. Nutricia Composition with docosapentaenoic acid
EP1800675B1 (en) * 2005-12-23 2011-05-18 N.V. Nutricia Composition comprising polyunsaturated fatty acids, proteins, manganese and/or molybden and nucleosides/nucleotides for treating dementia
JP5552313B2 (ja) * 2006-11-01 2014-07-16 プロノヴァ・バイオファーマ・ノルゲ・アーエス 脂質化合物
BRPI0717883A2 (pt) 2006-11-01 2013-10-29 Pronova Biopharma Norge As Compostos lipídicos, composição contendo os mesmos e uso dos referidos compostos
WO2008053340A1 (en) * 2006-11-03 2008-05-08 Pronova Biopharma Norge As A combination product comprising at least one lipid substituted in the alpha position and at least one hypoglycemic agent
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ES2345241B1 (es) 2009-03-16 2011-09-08 Lipopharma Therapeutics Uso de 2-hidroxiderivados de acidos grasos poliinsaturados como medicamentos.
ES2401629B1 (es) * 2011-10-07 2014-03-04 Universitat De Les Illes Balears Enantiómeros de 2-hidroxiderivados de ácidos grasos y su uso como medicamentos.

Also Published As

Publication number Publication date
KR101833772B1 (ko) 2018-03-02
BRPI1009860A8 (pt) 2019-12-17
AU2016238970A1 (en) 2016-11-03
RU2011141850A (ru) 2013-04-27
AU2019226257A1 (en) 2019-09-26
US10201515B2 (en) 2019-02-12
KR20180021931A (ko) 2018-03-05
PT2409963T (pt) 2017-02-15
KR20200024953A (ko) 2020-03-09
PT3159329T (pt) 2020-11-13
CN102356057A (zh) 2012-02-15
CN109999018A (zh) 2019-07-12
CN106420686A (zh) 2017-02-22
JP2012520344A (ja) 2012-09-06
HK1232207A1 (zh) 2018-01-05
US9907772B2 (en) 2018-03-06
DK3159329T3 (da) 2020-11-09
WO2010106211A1 (es) 2010-09-23
MX2011009614A (es) 2012-01-20
HUE032027T2 (en) 2017-08-28
CA2754963C (en) 2022-02-08
AU2020205213A1 (en) 2020-07-30
KR20110137365A (ko) 2011-12-22
AU2020205214B2 (en) 2021-02-18
RU2513995C2 (ru) 2014-04-27
US20200352891A1 (en) 2020-11-12
CL2011002268A1 (es) 2012-01-27
DK2409963T3 (en) 2017-02-27
ES2820025T3 (es) 2021-04-19
US11253497B2 (en) 2022-02-22
AU2020205213B2 (en) 2021-02-25
AU2010224749B2 (en) 2016-07-07
US20160158181A1 (en) 2016-06-09
ES2345241A1 (es) 2010-09-17
ES2613606T3 (es) 2017-05-24
EP3159329A1 (en) 2017-04-26
AU2018203976B2 (en) 2019-06-06
BRPI1009860A2 (pt) 2016-03-08
AU2020205214A1 (en) 2020-07-30
US9763907B2 (en) 2017-09-19
SI3159329T1 (sl) 2021-01-29
CN106349058A (zh) 2017-01-25
AU2018203976A1 (en) 2018-06-21
US20190365690A1 (en) 2019-12-05
US20120108550A1 (en) 2012-05-03
AU2019226257B2 (en) 2020-05-07
US9161928B2 (en) 2015-10-20
EP2409963B1 (en) 2017-01-04
KR20190018754A (ko) 2019-02-25
CN106349058B (zh) 2020-01-14
US9763906B2 (en) 2017-09-19
EP2409963A4 (en) 2013-10-02
CA2754963A1 (en) 2010-09-23
KR102233102B1 (ko) 2021-03-26
AU2016238970B2 (en) 2018-03-08
AU2010224749A1 (en) 2011-10-13
US20170035720A1 (en) 2017-02-09
ES2345241B1 (es) 2011-09-08
CN106420686B (zh) 2020-05-22
US20160158180A1 (en) 2016-06-09
JP5904592B2 (ja) 2016-04-13
EP2409963A1 (en) 2012-01-25
US20180085332A1 (en) 2018-03-29
HUE051850T2 (hu) 2021-03-29
EP3159329B1 (en) 2020-08-12

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