PL2305275T3 - Ciekła kompozycja zawierająca koordynacyjny związek cisplatyny - Google Patents

Ciekła kompozycja zawierająca koordynacyjny związek cisplatyny

Info

Publication number
PL2305275T3
PL2305275T3 PL09769989T PL09769989T PL2305275T3 PL 2305275 T3 PL2305275 T3 PL 2305275T3 PL 09769989 T PL09769989 T PL 09769989T PL 09769989 T PL09769989 T PL 09769989T PL 2305275 T3 PL2305275 T3 PL 2305275T3
Authority
PL
Poland
Prior art keywords
cisplatin
liquid composition
coordinating compound
coordinating
compound
Prior art date
Application number
PL09769989T
Other languages
English (en)
Inventor
Kazunori Kataoka
Nobuhiro Nishiyama
Chieko Tsuchiya
Tatsuyuki Hayashi
Original Assignee
Nanocarrier Co Ltd
Univ Tokyo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nanocarrier Co Ltd, Univ Tokyo filed Critical Nanocarrier Co Ltd
Publication of PL2305275T3 publication Critical patent/PL2305275T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/243Platinum; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6905Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion
    • A61K47/6907Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion the form being a microemulsion, nanoemulsion or micelle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
    • C08G69/02Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
    • C08G69/08Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids derived from amino-carboxylic acids
    • C08G69/10Alpha-amino-carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
    • C08G69/40Polyamides containing oxygen in the form of ether groups
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02Polyamines
    • C08G73/0233Polyamines derived from (poly)oxazolines, (poly)oxazines or having pendant acyl groups
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08KUse of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00Use of organic ingredients
    • C08K5/0091Complexes with metal-heteroatom-bonds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Dispersion Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Biophysics (AREA)
  • Nanotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polyamides (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL09769989T 2008-06-24 2009-05-27 Ciekła kompozycja zawierająca koordynacyjny związek cisplatyny PL2305275T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2008164814 2008-06-24
PCT/JP2009/060102 WO2009157279A1 (ja) 2008-06-24 2009-05-27 シスプラチン配位化合物の液体組成物
EP09769989.6A EP2305275B1 (en) 2008-06-24 2009-05-27 Liquid composition comprising cisplatin-coordinating compound

Publications (1)

Publication Number Publication Date
PL2305275T3 true PL2305275T3 (pl) 2013-12-31

Family

ID=41444348

Family Applications (1)

Application Number Title Priority Date Filing Date
PL09769989T PL2305275T3 (pl) 2008-06-24 2009-05-27 Ciekła kompozycja zawierająca koordynacyjny związek cisplatyny

Country Status (13)

Country Link
US (1) US8895076B2 (pl)
EP (1) EP2305275B1 (pl)
JP (1) JP5458255B2 (pl)
KR (1) KR101650907B1 (pl)
CN (1) CN102076345B (pl)
AU (1) AU2009263529B2 (pl)
CA (1) CA2728502C (pl)
DK (1) DK2305275T3 (pl)
ES (1) ES2425772T3 (pl)
HK (1) HK1154801A1 (pl)
PL (1) PL2305275T3 (pl)
TW (1) TWI428145B (pl)
WO (1) WO2009157279A1 (pl)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011105792A (ja) * 2009-11-12 2011-06-02 Japan Science & Technology Agency ブロックコポリマー、ブロックコポリマー−金属錯体複合体、及びそれを用いた中空構造体キャリア
TWI568453B (zh) * 2011-11-22 2017-02-01 原創生醫股份有限公司 具有螯合型複合微胞之藥物載體及其應用
CN102604082B (zh) * 2012-02-15 2013-12-11 中国科学院长春应用化学研究所 顺铂配合物及其制备方法
CN103272244A (zh) * 2013-01-21 2013-09-04 长春理工大学 一种药物键合物、制法及其在治疗肿瘤的应用
AU2015369185B2 (en) 2014-12-26 2020-10-22 Nippon Kayaku Kabushiki Kaisha Pharmaceutical preparation of camptothecin-containing polymer derivative
CA2990369A1 (en) 2015-06-24 2016-12-29 Nippon Kayaku Kabushiki Kaisha Novel platinum (iv) complex
KR20180039628A (ko) * 2015-09-03 2018-04-18 니폰 가야꾸 가부시끼가이샤 캄프토테신류 고분자 유도체를 함유하는 의약 조성물
JP6725520B2 (ja) 2015-09-14 2020-07-22 日本化薬株式会社 6配位白金錯体の高分子結合体
EP3395857B1 (en) 2015-12-22 2021-05-26 Nippon Kayaku Kabushiki Kaisha Polymer conjugate of sulfoxide derivative-coordinated platinum(ii) complex
JPWO2018038240A1 (ja) * 2016-08-26 2019-06-24 公益財団法人川崎市産業振興財団 金属とブロック共重合体との錯体を含むミセルを安定化させる方法および安定化されたミセル、並びにミセルからの金属の放出制御法
WO2019217328A1 (en) 2018-05-07 2019-11-14 California Institute Of Technology Gel and polymer based flow meters
CN109908084B (zh) * 2019-04-11 2021-06-25 临沂大学 一种铂交联喜树碱前药胶束纳米药物及其制备方法和应用
US11668613B2 (en) * 2019-05-06 2023-06-06 California Institute Of Technology ABA type block co-polymers for temperature sensing and flow meters
CN112121176B (zh) * 2019-06-24 2022-07-01 山东华铂凯盛生物科技有限公司 一种顺铂微粒组成、制备方法及应用
US11912807B2 (en) 2020-03-25 2024-02-27 Samsung Electronics Co., Ltd. Composite for sensing heat or infrared light and device including same

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9604895A (pt) 1995-04-14 1999-11-30 Kazunori Kataoka Polioxietileno tendo um açúcar em uma extremidade e um grupo funcional diferente na outra extremidade, e um processo para a produção do mesmo
NZ305471A (en) 1995-04-19 2000-02-28 Kazunori Kataoka Use of heterotelechelic block copolymers as carriers for medicaments
BR9610053A (pt) 1995-08-10 1999-07-06 Katoaka Kazunori Polímetro de blocos tendo grupos funcionais sobre ambas extremidades
DE60121016T2 (de) 2000-09-26 2006-12-21 Toudai Tlo, Ltd. Polymere mizelle mit darin eingeschlossenem cisplatin und ihre verwendung
US7094810B2 (en) * 2001-06-08 2006-08-22 Labopharm, Inc. pH-sensitive block copolymers for pharmaceutical compositions
JP2003012505A (ja) * 2001-07-06 2003-01-15 Nano Career Kk 薬物含有高分子ミセルの凍結乾燥
WO2006057429A1 (ja) * 2004-11-24 2006-06-01 Nanocarrier Co., Ltd. ブロックコポリマーのモーフォロジ-の変化方法
WO2007066781A1 (ja) * 2005-12-05 2007-06-14 Nanocarrier Co., Ltd. フッ素系有機溶媒を用いた薬物封入ポリマーミセルを含有する医薬組成物の製造方法

Also Published As

Publication number Publication date
US20110110881A1 (en) 2011-05-12
CA2728502C (en) 2017-01-03
AU2009263529B2 (en) 2013-09-26
JPWO2009157279A1 (ja) 2011-12-08
ES2425772T3 (es) 2013-10-17
KR20110038629A (ko) 2011-04-14
TWI428145B (zh) 2014-03-01
HK1154801A1 (en) 2012-05-04
WO2009157279A1 (ja) 2009-12-30
DK2305275T3 (da) 2013-10-07
CN102076345A (zh) 2011-05-25
JP5458255B2 (ja) 2014-04-02
US8895076B2 (en) 2014-11-25
EP2305275A1 (en) 2011-04-06
EP2305275A4 (en) 2012-07-18
KR101650907B1 (ko) 2016-08-24
EP2305275B1 (en) 2013-07-10
TW201006497A (en) 2010-02-16
CN102076345B (zh) 2013-05-08
CA2728502A1 (en) 2009-12-30
AU2009263529A1 (en) 2009-12-30

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