PL2280717T3 - Środek terapeutyczny dla chorób beztlenowych - Google Patents

Środek terapeutyczny dla chorób beztlenowych

Info

Publication number
PL2280717T3
PL2280717T3 PL09733604T PL09733604T PL2280717T3 PL 2280717 T3 PL2280717 T3 PL 2280717T3 PL 09733604 T PL09733604 T PL 09733604T PL 09733604 T PL09733604 T PL 09733604T PL 2280717 T3 PL2280717 T3 PL 2280717T3
Authority
PL
Poland
Prior art keywords
therapeutic agent
anaerobic diseases
anaerobic
diseases
therapeutic
Prior art date
Application number
PL09733604T
Other languages
English (en)
Inventor
Takayuki Sasaki
Hitomi Shimizu
Yuko Shimatani-Shibata
Hiromi Yonekura
Original Assignee
Anaeropharma Science, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anaeropharma Science, Inc. filed Critical Anaeropharma Science, Inc.
Publication of PL2280717T3 publication Critical patent/PL2280717T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7016—Disaccharides, e.g. lactose, lactulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/746—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for lactic acid bacteria (Streptococcus; Lactococcus; Lactobacillus; Pediococcus; Enterococcus; Leuconostoc; Propionibacterium; Bifidobacterium; Sporolactobacillus)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Mycology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL09733604T 2008-04-17 2009-04-17 Środek terapeutyczny dla chorób beztlenowych PL2280717T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12452808P 2008-04-17 2008-04-17
PCT/JP2009/001776 WO2009128275A1 (en) 2008-04-17 2009-04-17 Therapeutic agent for anaerobic diseases
EP09733604.4A EP2280717B1 (en) 2008-04-17 2009-04-17 Therapeutic agent for anaerobic diseases

Publications (1)

Publication Number Publication Date
PL2280717T3 true PL2280717T3 (pl) 2018-10-31

Family

ID=40792658

Family Applications (2)

Application Number Title Priority Date Filing Date
PL09733074T PL2274422T3 (pl) 2008-04-17 2009-04-16 Wektor ekspresyjny
PL09733604T PL2280717T3 (pl) 2008-04-17 2009-04-17 Środek terapeutyczny dla chorób beztlenowych

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL09733074T PL2274422T3 (pl) 2008-04-17 2009-04-16 Wektor ekspresyjny

Country Status (12)

Country Link
US (3) US8383398B2 (pl)
EP (2) EP2274422B1 (pl)
JP (3) JP5735804B2 (pl)
KR (3) KR101674977B1 (pl)
CN (2) CN102046791B (pl)
CA (2) CA2721653C (pl)
DK (2) DK2274422T3 (pl)
ES (2) ES2628378T3 (pl)
HU (2) HUE033561T2 (pl)
PL (2) PL2274422T3 (pl)
PT (2) PT2274422T (pl)
WO (2) WO2009128272A1 (pl)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9730968B2 (en) 2008-04-17 2017-08-15 Anaeropharma Science, Inc. Therapeutic agent for ischemic diseases
US20130095072A1 (en) * 2010-01-29 2013-04-18 Anaeropharma Science, Inc. Therapeutic agent for ischemic diseases
WO2009128272A1 (en) * 2008-04-17 2009-10-22 Anaeropharma Science, Inc. Expression vector
US8338162B2 (en) * 2009-04-17 2012-12-25 Anaeropharma Science, Inc. Obligately anaerobic mutant lactic acid bacterium and preparation method therefor, and expression vector functioning in obligately anaerobic lactic acid bacterium
EP2896695A3 (en) 2010-01-29 2015-09-23 Anaeropharma Science, Inc. Transformation plasmid
WO2013008881A1 (ja) 2011-07-13 2013-01-17 株式会社アネロファーマ・サイエンス 虚血性疾患治療薬
JP6755465B2 (ja) 2014-12-03 2020-09-16 株式会社アネロファーマ・サイエンス 共発現プラスミド
JP6258526B2 (ja) * 2015-01-19 2018-01-10 国立大学法人信州大学 虚血性疾患治療薬
LU100900B1 (de) * 2018-08-10 2020-02-17 Thomas Melchior Homann Verbindungen zur modulation von a-ketoglutarsäure (2kg)-abhängigen oxygenasen
US20220281998A1 (en) 2019-08-28 2022-09-08 Azusapharma Sciences, Inc. Bifidobacterium spp. expressing and secreting diabody-type bsab
CN112999215B (zh) * 2019-12-20 2024-06-21 复旦大学 呋喃酮糖苷类化合物的应用
CN115400154A (zh) * 2022-08-10 2022-11-29 深圳未知君生物科技有限公司 长双歧杆菌在制备治疗自闭症谱系障碍的药物中的应用
WO2024187069A1 (en) * 2023-03-08 2024-09-12 University Of Florida Research Foundation, Incorporated Engineering enterobacteria to site-specifically activate the anticancer prodrug 5-fluorocytosine for treating colon cancer

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8713601D0 (en) * 1987-06-10 1987-07-15 Unilever Plc Fermentation
WO1991009131A1 (en) * 1989-12-20 1991-06-27 Valio Finnish Cooperative Dairies Association Cloning vector for use in lactic acid bacteria
US6416754B1 (en) 1994-03-03 2002-07-09 The Board Of Trustees Of The Leland Stanford Junior University Anaerobe targeted enzyme-mediated prodrug therapy
US6984513B2 (en) * 1994-03-03 2006-01-10 The Board Of Trustees Of The Leland Stanford Junior University Anaerobe targeted enzyme-mediated prodrug therapy
TW357191B (en) * 1996-06-04 1999-05-01 Food Industry Development Res Institute Bifidobacteria strains with acid, bile salt and oxygen tolerance and their culture method the invention relates to bifidobacteria strains with acid, bile salt and oxygen tolerance and their culture method
JP2000060541A (ja) * 1998-08-27 2000-02-29 Fuyuki Mitsuyama ビフィズス菌増殖促進物質と整腸物質とビフィズス菌製剤
JP3642755B2 (ja) * 2000-09-21 2005-04-27 純 天野 嫌気性菌を用いた遺伝子治療用医薬
CA2342040C (en) * 2000-09-21 2012-07-10 Kyowa Hakko Kogyo Co., Ltd. Anaerobic bacterium as a drug for cancer gene therapy
JP2004528278A (ja) * 2000-12-18 2004-09-16 ボード オブ レジェンツ，ザ ユニバーシティー オブ テキサス システム インサイチュヒドロゲルを用いた、局所領域の化学療法および放射線治療
KR100457879B1 (ko) * 2001-02-24 2004-11-18 주식회사 비피도 비피도박테리움 유래 신규 플라스미드, 이를 이용한 재조합 발현 벡터 및 형질전환 방법
ATE495246T1 (de) 2004-11-24 2011-01-15 Anaeropharma Science Inc Neuartiger shuttle-vektor
PL1846022T3 (pl) * 2005-01-21 2016-06-30 Univ New York State Res Found Sposoby leczenia zarostowego zapalenia torebki stawowej
US8734779B2 (en) * 2005-04-08 2014-05-27 Anaeropharma Science Inc. 5-fluorouracil-resistant bacteria and method for production thereof
AU2007230844A1 (en) * 2006-03-27 2007-10-04 Government Of The United States Of America, As Represented By The Secretary Tetracycline compounds and methods of treatment
WO2007121100A2 (en) * 2006-04-13 2007-10-25 Ambrozea, Inc. Compositions and methods for producing fermentation products and residuals
US8911721B2 (en) * 2006-05-24 2014-12-16 Anaeropharma Science, Inc. Method of constructing gene transport support
WO2009128272A1 (en) * 2008-04-17 2009-10-22 Anaeropharma Science, Inc. Expression vector

Also Published As

Publication number Publication date
WO2009128275A9 (en) 2010-11-11
KR20160102584A (ko) 2016-08-30
US20110110893A1 (en) 2011-05-12
EP2274422B1 (en) 2017-03-15
CN102046791B (zh) 2013-09-18
EP2280717B1 (en) 2018-05-30
PL2274422T3 (pl) 2017-09-29
HUE033561T2 (hu) 2017-12-28
EP2280717A1 (en) 2011-02-09
JP2011517929A (ja) 2011-06-23
JP5514735B2 (ja) 2014-06-04
US20090264513A1 (en) 2009-10-22
US8470311B2 (en) 2013-06-25
KR20100134765A (ko) 2010-12-23
KR101674977B1 (ko) 2016-11-10
KR20110021784A (ko) 2011-03-04
WO2009128275A4 (en) 2010-02-18
WO2009128272A4 (en) 2010-02-18
DK2274422T3 (en) 2017-07-03
KR101671283B1 (ko) 2016-11-02
EP2274422A1 (en) 2011-01-19
CA2721653C (en) 2018-03-20
JP2011518112A (ja) 2011-06-23
PT2280717T (pt) 2018-10-04
ES2686080T3 (es) 2018-10-16
CA2721664C (en) 2018-01-23
PT2274422T (pt) 2017-06-28
JP2015091243A (ja) 2015-05-14
CA2721653A1 (en) 2009-10-22
HUE039768T2 (hu) 2019-02-28
WO2009128275A1 (en) 2009-10-22
US20130122582A1 (en) 2013-05-16
ES2628378T3 (es) 2017-08-02
WO2009128272A1 (en) 2009-10-22
JP6089025B2 (ja) 2017-03-01
CN102046791A (zh) 2011-05-04
JP5735804B2 (ja) 2015-06-17
CA2721664A1 (en) 2009-10-22
US8383398B2 (en) 2013-02-26
WO2009128272A9 (en) 2010-11-11
DK2280717T3 (en) 2018-09-10
CN102046190B (zh) 2013-03-13
CN102046190A (zh) 2011-05-04

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