PL2252575T3 - Pochodne 2-amino-2-fenyloalkanolu, ich wytwarzanie i kompozycje farmaceutyczne, które je zawierają - Google Patents

Pochodne 2-amino-2-fenyloalkanolu, ich wytwarzanie i kompozycje farmaceutyczne, które je zawierają

Info

Publication number
PL2252575T3
PL2252575T3 PL09720924T PL09720924T PL2252575T3 PL 2252575 T3 PL2252575 T3 PL 2252575T3 PL 09720924 T PL09720924 T PL 09720924T PL 09720924 T PL09720924 T PL 09720924T PL 2252575 T3 PL2252575 T3 PL 2252575T3
Authority
PL
Poland
Prior art keywords
amino
preparation
pharmaceutical compositions
compositions containing
containing same
Prior art date
Application number
PL09720924T
Other languages
English (en)
Inventor
Alexis Denis
Jean Pachot
Christophe Dini
Original Assignee
Oroxcell
Alexis Denis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oroxcell, Alexis Denis filed Critical Oroxcell
Publication of PL2252575T3 publication Critical patent/PL2252575T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/16—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C219/02—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C219/20—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C219/22—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/40—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings
    • C07C271/42—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/48—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C333/00—Derivatives of thiocarbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C333/02—Monothiocarbamic acids; Derivatives thereof
    • C07C333/04—Monothiocarbamic acids; Derivatives thereof having nitrogen atoms of thiocarbamic groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/32—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D317/34—Oxygen atoms
    • C07D317/40—Vinylene carbonate; Substituted vinylene carbonates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
PL09720924T 2008-01-31 2009-01-30 Pochodne 2-amino-2-fenyloalkanolu, ich wytwarzanie i kompozycje farmaceutyczne, które je zawierają PL2252575T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR0800521A FR2927076B1 (fr) 2008-01-31 2008-01-31 Derives de 2-amino-2-phenyl-alkanol, leur preparation et les compositions pharmaceutiques qui les contiennent
US8482908P 2008-07-30 2008-07-30
EP09720924A EP2252575B1 (fr) 2008-01-31 2009-01-30 Derives de 2-amino-2-phenyl-alkanol, leur preparation et les compositions pharmaceutiques qui les contiennent
PCT/FR2009/000106 WO2009112703A1 (fr) 2008-01-31 2009-01-30 Derives de 2-amino-2-phenyl-alkanol, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
PL2252575T3 true PL2252575T3 (pl) 2013-05-31

Family

ID=39273809

Family Applications (1)

Application Number Title Priority Date Filing Date
PL09720924T PL2252575T3 (pl) 2008-01-31 2009-01-30 Pochodne 2-amino-2-fenyloalkanolu, ich wytwarzanie i kompozycje farmaceutyczne, które je zawierają

Country Status (24)

Country Link
US (1) US8217075B2 (pl)
EP (1) EP2252575B1 (pl)
JP (1) JP5497665B2 (pl)
KR (1) KR20110103834A (pl)
CN (1) CN101932552B (pl)
AU (1) AU2009224558B2 (pl)
BR (1) BRPI0907097A2 (pl)
CA (1) CA2712489A1 (pl)
DK (1) DK2252575T3 (pl)
ES (1) ES2400080T3 (pl)
FR (1) FR2927076B1 (pl)
GE (1) GEP20125563B (pl)
IL (1) IL206936A (pl)
MA (1) MA32125B1 (pl)
MX (1) MX2010008430A (pl)
MY (1) MY152406A (pl)
NZ (1) NZ587677A (pl)
PL (1) PL2252575T3 (pl)
PT (1) PT2252575E (pl)
RU (1) RU2486174C2 (pl)
TW (1) TWI393561B (pl)
UA (1) UA101013C2 (pl)
WO (1) WO2009112703A1 (pl)
ZA (1) ZA201005316B (pl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2948660B1 (fr) 2009-07-30 2011-08-19 Oroxcell Derives de 2-amino-2-phenyl-alkanol, leur preparation et les compositions pharmaceutiques qui les contiennent
CN102276487B (zh) * 2011-06-29 2013-06-12 岳阳亚王精细化工有限公司 一种曲美布汀的制备方法
WO2022225427A1 (ru) * 2021-04-22 2022-10-27 Общество С Ограниченной Ответственностью "Валента-Интеллект" Новые соли [2-(диметиламино)-2-фенилбутил]-3,4,5-триметоксибензоата и их применение

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1434826A (en) * 1973-11-14 1976-05-05 Gallardo Antonio Sa Esters and carbamates of aminoalkanols
FR2669333B1 (fr) 1990-11-16 1993-03-19 Univ Rouen Procede de separation des enantiomeres des 5-aryl-5-alkylhydantouines.
DE4426245A1 (de) * 1994-07-23 1996-02-22 Gruenenthal Gmbh 1-Phenyl-3-dimethylamino-propanverbindungen mit pharmakologischer Wirkung
FR2765218B1 (fr) 1997-06-30 1999-08-13 Jouveinal Inst Rech Le (s) 3,4,5-trimethoxybenzoate de 2-methylamino-2-phenyl-n- butyle, son application au traitement des douleurs chroniques
EP1110549A1 (en) * 1999-12-23 2001-06-27 Warner-Lambert Company Use of trimebutine for treating pain
SV2001000242A (es) * 1999-12-23 2001-10-25 Warner Lambert Co Combinacion de trimebutina con un analgesico derivado del opio
TW200524868A (en) * 2003-07-31 2005-08-01 Zeria Pharm Co Ltd Benzylamine derivatives
EP2024323B1 (en) * 2006-06-06 2013-03-27 Gicare Pharma Inc. Salts of trimebutine and n-desmethyl trimebutine

Also Published As

Publication number Publication date
JP2011510961A (ja) 2011-04-07
US20090197924A1 (en) 2009-08-06
RU2010136307A (ru) 2012-03-10
MA32125B1 (fr) 2011-03-01
EP2252575B1 (fr) 2012-12-19
KR20110103834A (ko) 2011-09-21
DK2252575T3 (da) 2013-02-18
AU2009224558B2 (en) 2013-05-02
ES2400080T3 (es) 2013-04-05
IL206936A0 (en) 2010-12-30
TW200942230A (en) 2009-10-16
CN101932552A (zh) 2010-12-29
UA101013C2 (ru) 2013-02-25
CA2712489A1 (en) 2009-09-17
FR2927076A1 (fr) 2009-08-07
TWI393561B (zh) 2013-04-21
ZA201005316B (en) 2011-10-26
PT2252575E (pt) 2013-03-05
MY152406A (en) 2014-09-30
NZ587677A (en) 2012-06-29
MX2010008430A (es) 2010-12-07
US8217075B2 (en) 2012-07-10
AU2009224558A1 (en) 2009-09-17
FR2927076B1 (fr) 2010-03-26
GEP20125563B (en) 2012-06-25
IL206936A (en) 2013-08-29
BRPI0907097A2 (pt) 2015-07-07
RU2486174C2 (ru) 2013-06-27
EP2252575A1 (fr) 2010-11-24
WO2009112703A1 (fr) 2009-09-17
JP5497665B2 (ja) 2014-05-21
HK1147090A1 (en) 2011-07-29
WO2009112703A8 (fr) 2009-12-03
CN101932552B (zh) 2014-06-18

Similar Documents

Publication Publication Date Title
IL214175A (en) Derivatives of aminotetralin, their pharmaceutical compositions and their use
IL204521A0 (en) Oxadiazole derivatives, their preparation and pharmaceutical compositions containing them
IL200206A (en) The history of quinaxaline, their preparation and their pharmaceutical preparations
IL208203A (en) Annotations of 3,2-Dihydro-Pyrido-4,1-Exazine and 3,2-Dihydro-4-Oxa-9,1-Diazapananthrene, Preparation Processes and Pharmaceutical Preparations
IL206808A (en) Indolyl-pyridone history, their pharmaceutical preparations and their uses
IL216254A (en) Compounds, pharmaceutical compositions and their uses
IL219602A0 (en) Tricylic pyrazol amine derivatives, their preparation and pharmaceutical compositions containing them
IL193772A0 (en) 4-oxoquinoline derivatives,methods for the preparation thereof and pharmaceutical compositions containing the same
IL206594A (en) The history of azinone-tetrahydropyridoindole and its containing pharmaceutical preparations
IL192826A0 (en) Thiazole derivatives, their preparation and pharmaceutical compositions containing them
IL213452A0 (en) Phenylpyrimidone compounds, pharmaceutical compositions, preparation methods and uses thereof
IL225626A0 (en) The history of pyrrolidinone, their preparation and remote preparations containing them
IL216113A (en) Processed derivatives of indazole and azaza-indazole, pharmaceutical preparations containing them and their uses
IL211018A (en) Inhibitors, processes for making them, medicinal preparations containing them and their use
EP2447253A4 (en) DIHYDROPYRIMIDIN COMPOUNDS AND MANUFACTURING METHOD, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF
IL215497A0 (en) Oxadiazile derivatives and pharmaceutical compositions containing them
IL210377A (en) History of Naphthyridone, their preparation and their pharmaceutical preparations
IL213570A (en) History 8 - Alkoxy - s - Triazolo [5,1 - a] pyridine and pharmaceutical preparations containing them
IL217500A0 (en) Tetrazole derivatives, their preparartion and pharmaceutical compositions containing them
IL210316A (en) History of Triazol Pharmacopoeias that contain them and their uses
EP2261221A4 (en) EPOTHILONE ANALOGUES, THEIR PHARMACEUTICAL COMPOSITIONS, THEIR USE AND PREPARATIONS
PL394605A1 (pl) Trwała złożona kompozycja farmaceutyczna
IL212942A (en) History of Rifamycin, Methods of Preparation, Pharmaceutical Preparations Containing Them and Their Uses
PT2504331E (pt) Composto, novas formas desse composto, composições farmacêuticas desse composto e métodos de preparação e utilização
SI2231598T1 (sl) Novi derivati diazeniumdiolata postopek pripravele teh in njihovi farmacevtski sestavki