PL2144611T3 - Aktywność przeciwnowotworowa temsyrolimus wobec brodawkowatego raka nerkowokomórkowego - Google Patents

Aktywność przeciwnowotworowa temsyrolimus wobec brodawkowatego raka nerkowokomórkowego

Info

Publication number
PL2144611T3
PL2144611T3 PL08742616T PL08742616T PL2144611T3 PL 2144611 T3 PL2144611 T3 PL 2144611T3 PL 08742616 T PL08742616 T PL 08742616T PL 08742616 T PL08742616 T PL 08742616T PL 2144611 T3 PL2144611 T3 PL 2144611T3
Authority
PL
Poland
Prior art keywords
temsirolimus
renal cell
tumor activity
cell cancer
papillary renal
Prior art date
Application number
PL08742616T
Other languages
English (en)
Inventor
Gary Dukart
James Joseph Gibbons Jr
Anna Berkenblit
Jay Marshall Feingold
Original Assignee
Wyeth Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39619123&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2144611(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wyeth Llc filed Critical Wyeth Llc
Publication of PL2144611T3 publication Critical patent/PL2144611T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
PL08742616T 2007-04-10 2008-04-08 Aktywność przeciwnowotworowa temsyrolimus wobec brodawkowatego raka nerkowokomórkowego PL2144611T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US92275907P 2007-04-10 2007-04-10
PCT/US2008/004501 WO2008124125A1 (en) 2007-04-10 2008-04-08 Anti-tumor activity of temsirolimus in papillary renal cell cancer
EP08742616.9A EP2144611B9 (en) 2007-04-10 2008-04-08 Anti-tumor activity of temsirolimus in papillary renal cell cancer

Publications (1)

Publication Number Publication Date
PL2144611T3 true PL2144611T3 (pl) 2015-10-30

Family

ID=39619123

Family Applications (2)

Application Number Title Priority Date Filing Date
PL08742616T PL2144611T3 (pl) 2007-04-10 2008-04-08 Aktywność przeciwnowotworowa temsyrolimus wobec brodawkowatego raka nerkowokomórkowego
PL12153823.5T PL2462934T3 (pl) 2007-04-10 2008-04-08 Aktywność przeciwnowotworowa temsyrolimus wobec brodawkowatego raka nerkowokomórkowego

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL12153823.5T PL2462934T3 (pl) 2007-04-10 2008-04-08 Aktywność przeciwnowotworowa temsyrolimus wobec brodawkowatego raka nerkowokomórkowego

Country Status (24)

Country Link
US (1) US8791097B2 (pl)
EP (5) EP2144611B9 (pl)
JP (2) JP5908669B2 (pl)
KR (2) KR20150002887A (pl)
CN (2) CN105769861A (pl)
AU (1) AU2008236621B2 (pl)
BR (1) BRPI0809322A2 (pl)
CA (1) CA2681451C (pl)
CL (1) CL2008001009A1 (pl)
CY (2) CY1116492T1 (pl)
DK (2) DK2462934T3 (pl)
ES (2) ES2586739T3 (pl)
HR (2) HRP20150678T1 (pl)
HU (2) HUE029052T2 (pl)
IL (1) IL200835A (pl)
MX (1) MX2009010954A (pl)
PA (1) PA8776101A1 (pl)
PL (2) PL2144611T3 (pl)
PT (2) PT2462934T (pl)
RU (1) RU2501559C2 (pl)
SI (2) SI2462934T1 (pl)
TW (1) TW200901989A (pl)
WO (1) WO2008124125A1 (pl)
ZA (1) ZA200907063B (pl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200901989A (en) * 2007-04-10 2009-01-16 Wyeth Corp Anti-tumor activity of CCI-779 in papillary renal cell cancer
EP2550964A1 (en) * 2011-07-26 2013-01-30 Universitat Pompeu-Fabra Temsirolimus for use in the prevention and/or treatment of a delta 9-tetrahydrocannabinol-induced anxiety disorder
US10765665B2 (en) 2015-11-24 2020-09-08 Melin Jeffrey Composition comprising combination of rapamycin and an activator of AMP kinase and use thereof for treating diseases
CN108143732A (zh) * 2017-12-19 2018-06-12 江南大学 雷帕霉素和ω-3脂肪酸在制备治疗肾癌的药物中的用途

Family Cites Families (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4316885A (en) 1980-08-25 1982-02-23 Ayerst, Mckenna And Harrison, Inc. Acyl derivatives of rapamycin
US4650803A (en) 1985-12-06 1987-03-17 University Of Kansas Prodrugs of rapamycin
US5023264A (en) 1990-07-16 1991-06-11 American Home Products Corporation Rapamycin oximes
US5023263A (en) 1990-08-09 1991-06-11 American Home Products Corporation 42-oxorapamycin
US5221670A (en) 1990-09-19 1993-06-22 American Home Products Corporation Rapamycin esters
US5233036A (en) 1990-10-16 1993-08-03 American Home Products Corporation Rapamycin alkoxyesters
US5120842A (en) 1991-04-01 1992-06-09 American Home Products Corporation Silyl ethers of rapamycin
US5100883A (en) 1991-04-08 1992-03-31 American Home Products Corporation Fluorinated esters of rapamycin
US5118678A (en) 1991-04-17 1992-06-02 American Home Products Corporation Carbamates of rapamycin
US5118677A (en) 1991-05-20 1992-06-02 American Home Products Corporation Amide esters of rapamycin
US5162333A (en) 1991-09-11 1992-11-10 American Home Products Corporation Aminodiesters of rapamycin
US5177203A (en) 1992-03-05 1993-01-05 American Home Products Corporation Rapamycin 42-sulfonates and 42-(N-carboalkoxy) sulfamates useful as immunosuppressive agents
US5256790A (en) 1992-08-13 1993-10-26 American Home Products Corporation 27-hydroxyrapamycin and derivatives thereof
GB9221220D0 (en) 1992-10-09 1992-11-25 Sandoz Ag Organic componds
US5434260A (en) 1992-10-13 1995-07-18 American Home Products Corporation Carbamates of rapamycin
US5302584A (en) 1992-10-13 1994-04-12 American Home Products Corporation Carbamates of rapamycin
US5480989A (en) 1992-10-13 1996-01-02 American Home Products Corporation Carbamates of rapamycin
US5480988A (en) 1992-10-13 1996-01-02 American Home Products Corporation Carbamates of rapamycin
US5489680A (en) 1992-10-13 1996-02-06 American Home Products Corporation Carbamates of rapamycin
US5411967A (en) 1992-10-13 1995-05-02 American Home Products Corporation Carbamates of rapamycin
US5262423A (en) 1992-10-29 1993-11-16 American Home Products Corporation Rapamycin arylcarbonyl and alkoxycarbonyl carbamates as immunosuppressive and antifungal agents
US5258389A (en) 1992-11-09 1993-11-02 Merck & Co., Inc. O-aryl, O-alkyl, O-alkenyl and O-alkynylrapamycin derivatives
US5260300A (en) 1992-11-19 1993-11-09 American Home Products Corporation Rapamycin carbonate esters as immuno-suppressant agents
US5504091A (en) 1993-04-23 1996-04-02 American Home Products Corporation Biotin esters of rapamycin
US5378836A (en) 1993-10-08 1995-01-03 American Home Products Corporation Rapamycin oximes and hydrazones
US5391730A (en) 1993-10-08 1995-02-21 American Home Products Corporation Phosphorylcarbamates of rapamycin and oxime derivatives thereof
US5373014A (en) 1993-10-08 1994-12-13 American Home Products Corporation Rapamycin oximes
US5385909A (en) 1993-11-22 1995-01-31 American Home Products Corporation Heterocyclic esters of rapamycin
US5385908A (en) 1993-11-22 1995-01-31 American Home Products Corporation Hindered esters of rapamycin
US5385910A (en) 1993-11-22 1995-01-31 American Home Products Corporation Gem-distributed esters of rapamycin
US5389639A (en) 1993-12-29 1995-02-14 American Home Products Company Amino alkanoic esters of rapamycin
US5362718A (en) 1994-04-18 1994-11-08 American Home Products Corporation Rapamycin hydroxyesters
US5463048A (en) 1994-06-14 1995-10-31 American Home Products Corporation Rapamycin amidino carbamates
US5491231A (en) 1994-11-28 1996-02-13 American Home Products Corporation Hindered N-oxide esters of rapamycin
US5563145A (en) 1994-12-07 1996-10-08 American Home Products Corporation Rapamycin 42-oximes and hydroxylamines
US5780462A (en) 1995-12-27 1998-07-14 American Home Products Corporation Water soluble rapamycin esters
EP0937082A2 (en) 1996-07-12 1999-08-25 Ariad Pharmaceuticals, Inc. Materials and method for treating or preventing pathogenic fungal infection
TW557297B (en) 1997-09-26 2003-10-11 Abbott Lab Rapamycin analogs having immunomodulatory activity, and pharmaceutical compositions containing same
DE60041291D1 (de) * 1999-04-08 2009-02-12 Schering Corp Behandlung von Nierenzellen-Karzinom
AU783158B2 (en) 1999-08-24 2005-09-29 Ariad Pharmaceuticals, Inc. 28-epirapalogs
US6277983B1 (en) 2000-09-27 2001-08-21 American Home Products Corporation Regioselective synthesis of rapamycin derivatives
TWI286074B (en) * 2000-11-15 2007-09-01 Wyeth Corp Pharmaceutical composition containing CCI-779 as an antineoplastic agent
TWI233359B (en) 2001-04-06 2005-06-01 Wyeth Corp Pharmaceutical composition for treating neoplasm
TWI296196B (en) 2001-04-06 2008-05-01 Wyeth Corp Antineoplastic combinations
US20020198137A1 (en) 2001-06-01 2002-12-26 Wyeth Antineoplastic combinations
UA77200C2 (en) 2001-08-07 2006-11-15 Wyeth Corp Antineoplastic combination of cci-779 and bkb-569
ATE385795T1 (de) 2002-07-30 2008-03-15 Wyeth Corp Parenterale formulierungen mit einem rapamycin hydroxyester
DK1635830T3 (da) 2002-09-17 2009-02-23 Wyeth Corp Granulatformulering af rapamycinesteren CCI-779
UA83484C2 (uk) 2003-03-05 2008-07-25 Уайт Спосіб лікування раку грудей комбінацією похідного рапаміцину і інгібітора ароматази - летрозолу, фармацевтична композиція
JP2006524246A (ja) * 2003-04-22 2006-10-26 ワイス 抗新生物組み合わせ
CA2523798A1 (en) * 2003-04-29 2004-11-11 Wyeth Methods for prognosis and treatment of solid tumors
MXPA06000951A (es) 2003-08-07 2006-03-30 Wyeth Corp Sintesis regioselectiva de cci-779.
AR047988A1 (es) 2004-03-11 2006-03-15 Wyeth Corp Combinaciones antineoplásicas de cci-779 y rituximab
TW200901989A (en) * 2007-04-10 2009-01-16 Wyeth Corp Anti-tumor activity of CCI-779 in papillary renal cell cancer

Also Published As

Publication number Publication date
SI2144611T1 (sl) 2015-08-31
EP3106164A1 (en) 2016-12-21
PL2462934T3 (pl) 2016-10-31
CA2681451A1 (en) 2008-10-16
WO2008124125A1 (en) 2008-10-16
KR20090130040A (ko) 2009-12-17
DK2462934T3 (en) 2016-08-15
SI2462934T1 (sl) 2016-07-29
HUE029052T2 (hu) 2017-01-30
US8791097B2 (en) 2014-07-29
MX2009010954A (es) 2009-10-29
KR101544222B1 (ko) 2015-08-12
CL2008001009A1 (es) 2008-10-17
PT2462934T (pt) 2016-08-17
EP3248601A1 (en) 2017-11-29
HUE026022T4 (hu) 2017-09-28
EP2462934B1 (en) 2016-06-08
JP5908669B2 (ja) 2016-04-26
RU2501559C2 (ru) 2013-12-20
EP3398597A1 (en) 2018-11-07
RU2009134479A (ru) 2011-05-20
ES2543853T3 (es) 2015-08-24
JP2010523660A (ja) 2010-07-15
HRP20150678T1 (hr) 2015-08-14
TW200901989A (en) 2009-01-16
ZA200907063B (en) 2011-03-30
AU2008236621A1 (en) 2008-10-16
IL200835A (en) 2015-09-24
EP2144611A1 (en) 2010-01-20
PT2144611E (pt) 2015-09-11
EP2144611B1 (en) 2015-06-17
IL200835A0 (en) 2010-05-17
US20080255177A1 (en) 2008-10-16
CY1116492T1 (el) 2017-03-15
HRP20160698T1 (hr) 2016-07-15
EP2462934A1 (en) 2012-06-13
HUE026022T2 (hu) 2016-05-30
ES2586739T3 (es) 2016-10-18
CA2681451C (en) 2016-08-02
EP2144611B9 (en) 2016-05-18
JP2015083595A (ja) 2015-04-30
CN101678008A (zh) 2010-03-24
CN105769861A (zh) 2016-07-20
DK2144611T3 (en) 2015-08-10
KR20150002887A (ko) 2015-01-07
PA8776101A1 (es) 2009-03-31
CY1117701T1 (el) 2017-05-17
BRPI0809322A2 (pt) 2014-09-23
AU2008236621B2 (en) 2013-06-27

Similar Documents

Publication Publication Date Title
TWI367949B (en) Predicting post-treatment survival in cancer patients with microrn
EP2115161A4 (en) GENETIC METHYLATION IN THE DIAGNOSIS OF CANCERS
IL225351A0 (en) Methods to inhibit the rapid proliferation of cells in cancers driven by egfr
EP2227691A4 (en) METHOD FOR THE DIAGNOSIS OF LUNG CANCER DISORDERS USING GENE EXPRESSION PROFILES IN MONONUCLEAR CELLS OF PERIPHERAL BLOOD
EP2201134A4 (en) GENE EXPRESSION SIGNATURES IN ENRICHED TUMOR CELL SAMPLES
IL199836A0 (en) Human cancer stem cells
EP2203746A4 (en) SUB-POPULATIONS OF LYMPHOCYTES T CAPABLE OF TREATING CANCER
HK1197267A1 (en) Isolated renal cells and uses thereof
IL202329A0 (en) Methods and compositions for stimulating cells
GB0720484D0 (en) Cells
EP2024515A4 (en) METHYLATION OF GENES IN THE DIAGNOSIS OF CANCER
ZA200907300B (en) Methods for counting cells
IL205831A0 (en) Kinesin inhibitors as cancer therapeutics
EP2172507A4 (en) POLYETHER Polycarbonate
EP2227540A4 (en) DIFFERENTIATION OF HUMAN CELLS
HK1137929A1 (en) Therapeutics for treating cancer using 3-bromopyruvate 3-
EP2188383A4 (en) SYSTEMS AND METHODS FOR MEASURING TRANSLATION ACTIVITY IN VIABLE CELLS
PL2102354T3 (pl) Urządzenie i sposoby osmotycznego szokowania komórek
GB0713672D0 (en) Method for cell manipulation
ZA200907063B (en) Anti-tumor activity of temsirolimus in papillary renal cell cancer
EP2155856A4 (en) SYSTEMS AND METHODS OF CELL TRAY
GB0606764D0 (en) Three dimensional cell culture
WO2011059926A9 (en) Methods and materials for treating renal cell carcinoma
EP2321641A4 (en) GENE METHYLATION IN THE DIAGNOSIS OF CANCER
EP2134365A4 (en) COMPOSITIONS AND METHODS FOR INHIBITING TUMOR CELL GROWTH