PL2094699T3 - Nowe pochodne imidazolonów, ich wytwarzanie jako leków, kompozycje farmaceutyczne i zastosowanie jako inhibitorów kinaz białkowych, zwłaszcza cdc7 - Google Patents
Nowe pochodne imidazolonów, ich wytwarzanie jako leków, kompozycje farmaceutyczne i zastosowanie jako inhibitorów kinaz białkowych, zwłaszcza cdc7Info
- Publication number
- PL2094699T3 PL2094699T3 PL07858418T PL07858418T PL2094699T3 PL 2094699 T3 PL2094699 T3 PL 2094699T3 PL 07858418 T PL07858418 T PL 07858418T PL 07858418 T PL07858418 T PL 07858418T PL 2094699 T3 PL2094699 T3 PL 2094699T3
- Authority
- PL
- Poland
- Prior art keywords
- drugs
- preparation
- pharmaceutical compositions
- protein kinase
- kinase inhibitors
- Prior art date
Links
- WZELXJBMMZFDDU-UHFFFAOYSA-N Imidazol-2-one Chemical class O=C1N=CC=N1 WZELXJBMMZFDDU-UHFFFAOYSA-N 0.000 title 1
- 229940045988 antineoplastic drug protein kinase inhibitors Drugs 0.000 title 1
- 101150065030 cdc7 gene Proteins 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 239000003909 protein kinase inhibitor Substances 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Physical Education & Sports Medicine (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Obesity (AREA)
- Rheumatology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Ophthalmology & Optometry (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0608924A FR2907120B1 (fr) | 2006-10-12 | 2006-10-12 | Nouveaux derives imidazolones,leur preparation a titre de medicaments,compositions pharmaceutiques,utilisation comme inhibiteurs de proteines kinases notamment cdc7 |
| EP07858418A EP2094699B1 (fr) | 2006-10-12 | 2007-10-10 | Nouveaux derives imidazolones, leur preparation a titre de medicaments, compositions pharmaceutiques, utilisation comme inhibiteurs de proteines kinases notamment cdc7 |
| PCT/FR2007/001651 WO2008046982A2 (fr) | 2006-10-12 | 2007-10-10 | Nouveaux derives imidazolones, leur preparation a titre de medicaments, compositions pharmaceutiques, utilisation comme inhibiteurs de proteines kinases notamment cdc7 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2094699T3 true PL2094699T3 (pl) | 2011-12-30 |
Family
ID=37964098
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL07858418T PL2094699T3 (pl) | 2006-10-12 | 2007-10-10 | Nowe pochodne imidazolonów, ich wytwarzanie jako leków, kompozycje farmaceutyczne i zastosowanie jako inhibitorów kinaz białkowych, zwłaszcza cdc7 |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US8314121B2 (pl) |
| EP (1) | EP2094699B1 (pl) |
| JP (1) | JP2010505922A (pl) |
| KR (1) | KR101552361B1 (pl) |
| CN (1) | CN101522678A (pl) |
| AR (1) | AR063249A1 (pl) |
| AT (1) | ATE517105T1 (pl) |
| AU (1) | AU2007311833B2 (pl) |
| BR (1) | BRPI0719790A2 (pl) |
| CA (1) | CA2660166C (pl) |
| CL (1) | CL2007002934A1 (pl) |
| CO (1) | CO6160310A2 (pl) |
| CY (1) | CY1112066T1 (pl) |
| DK (1) | DK2094699T3 (pl) |
| EA (1) | EA018496B1 (pl) |
| ES (1) | ES2370049T3 (pl) |
| FR (1) | FR2907120B1 (pl) |
| HR (1) | HRP20110759T1 (pl) |
| IL (1) | IL197452A (pl) |
| MA (1) | MA30877B1 (pl) |
| MX (1) | MX2009003283A (pl) |
| NO (1) | NO20091486L (pl) |
| PL (1) | PL2094699T3 (pl) |
| PT (1) | PT2094699E (pl) |
| RS (1) | RS51985B (pl) |
| SI (1) | SI2094699T1 (pl) |
| TW (1) | TW200821310A (pl) |
| UY (1) | UY30642A1 (pl) |
| WO (1) | WO2008046982A2 (pl) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20120024619A (ko) | 2009-04-20 | 2012-03-14 | 에스비아이 바이오테크 가부시키가이샤 | 티아졸리디논 유도체 |
| CA2767089A1 (en) | 2009-07-15 | 2011-01-20 | Abbott Laboratories | Pyrrolopyridine inhibitors of kinases |
| KR101851130B1 (ko) * | 2009-12-04 | 2018-04-23 | 센화 바이오사이언시즈 인코포레이티드 | Ｃｋ2 억제제로서 피라졸로피리미딘 및 관련된 헤테로사이클 |
| EP2560971B1 (en) | 2010-04-19 | 2014-04-09 | Abbvie Inc. | Pyrrolopyridines as inhibitors of kinases |
| US8742113B2 (en) | 2011-03-31 | 2014-06-03 | Sbi Biotech Co., Ltd. | Furanone derivative |
| JP6569908B2 (ja) | 2014-01-31 | 2019-09-04 | カルナバイオサイエンス株式会社 | 抗がん剤組成物 |
| GB201807147D0 (en) | 2018-05-01 | 2018-06-13 | Oncologica Uk Ltd | Therapeutic combination |
| US12533353B2 (en) | 2018-09-24 | 2026-01-27 | Carna Biosciences, Inc. | Methods of treatment of cancer comprising CDC7 inhibitors |
| EP4083037A4 (en) * | 2019-12-26 | 2024-01-24 | Yonsei University, University-Industry Foundation(UIF). | Pyrrolidine derivative, and pharmaceutical composition for preventing or treating beta-amyloid or tau protein-associated diseases containing same |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6335342B1 (en) | 2000-06-19 | 2002-01-01 | Pharmacia & Upjohn S.P.A. | Azaindole derivatives, process for their preparation, and their use as antitumor agents |
| EP2295433A3 (en) | 2003-03-06 | 2011-07-06 | Eisai R&D Management Co., Ltd. | JNK inhibitors |
| DE602004014163D1 (de) * | 2003-08-08 | 2008-07-10 | Pfizer Italia Srl | Pyrimidylpyrrolderivate, die als kinaseinhibitoren wirken |
| TW200604168A (en) | 2004-04-02 | 2006-02-01 | Vertex Pharma | Azaindoles useful as inhibitors of rock and other protein kinases |
| AU2005293831B2 (en) * | 2004-10-14 | 2011-01-06 | F. Hoffmann-La Roche Ag | Novel Azaindole thiazolinones as anti-cancer agents |
| US7371862B2 (en) * | 2005-11-11 | 2008-05-13 | Pfizer Italia S.R.L. | Azaindolylidene derivatives as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them |
-
2006
- 2006-10-12 FR FR0608924A patent/FR2907120B1/fr not_active Expired - Fee Related
-
2007
- 2007-10-10 EA EA200970364A patent/EA018496B1/ru not_active IP Right Cessation
- 2007-10-10 JP JP2009531874A patent/JP2010505922A/ja not_active Revoked
- 2007-10-10 CA CA2660166A patent/CA2660166C/fr not_active Expired - Fee Related
- 2007-10-10 ES ES07858418T patent/ES2370049T3/es active Active
- 2007-10-10 AT AT07858418T patent/ATE517105T1/de active
- 2007-10-10 WO PCT/FR2007/001651 patent/WO2008046982A2/fr not_active Ceased
- 2007-10-10 RS RS20110456A patent/RS51985B/sr unknown
- 2007-10-10 EP EP07858418A patent/EP2094699B1/fr active Active
- 2007-10-10 PL PL07858418T patent/PL2094699T3/pl unknown
- 2007-10-10 CN CNA2007800378600A patent/CN101522678A/zh active Pending
- 2007-10-10 SI SI200730750T patent/SI2094699T1/sl unknown
- 2007-10-10 AU AU2007311833A patent/AU2007311833B2/en not_active Ceased
- 2007-10-10 BR BRPI0719790-0A2A patent/BRPI0719790A2/pt not_active IP Right Cessation
- 2007-10-10 DK DK07858418.2T patent/DK2094699T3/da active
- 2007-10-10 MX MX2009003283A patent/MX2009003283A/es active IP Right Grant
- 2007-10-10 PT PT07858418T patent/PT2094699E/pt unknown
- 2007-10-10 KR KR1020097007392A patent/KR101552361B1/ko not_active Expired - Fee Related
- 2007-10-10 HR HR20110759T patent/HRP20110759T1/hr unknown
- 2007-10-11 CL CL200702934A patent/CL2007002934A1/es unknown
- 2007-10-11 AR ARP070104500A patent/AR063249A1/es unknown
- 2007-10-12 TW TW096138357A patent/TW200821310A/zh unknown
- 2007-10-12 UY UY30642A patent/UY30642A1/es not_active Application Discontinuation
-
2009
- 2009-03-05 IL IL197452A patent/IL197452A/en not_active IP Right Cessation
- 2009-03-31 US US12/415,391 patent/US8314121B2/en not_active Expired - Fee Related
- 2009-04-08 CO CO09036259A patent/CO6160310A2/es unknown
- 2009-04-16 NO NO20091486A patent/NO20091486L/no not_active Application Discontinuation
- 2009-05-08 MA MA31856A patent/MA30877B1/fr unknown
-
2011
- 2011-10-20 CY CY20111100996T patent/CY1112066T1/el unknown
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